Works matching AU Reddy, P. Hemachandra

Results: 122

A Combinational Therapy for Preventing and Delaying the Onset of Alzheimer's Disease: A Focus on Probiotic and Vitamin Co-Supplementation.

Published in:

Antioxidants, 2024, v. 13, n. 2, p. 202, doi. 10.3390/antiox13020202

By:

Sultana, Omme Fatema;
Hia, Raksa Andalib;
Reddy, P. Hemachandra

Publication type:

Article

Current Status of Obesity: Protective Role of Catechins.

Published in:

Antioxidants, 2023, v. 12, n. 2, p. 474, doi. 10.3390/antiox12020474

By:

Basu, Tanisha;
Selman, Ashley;
Reddy, Arubala P.;
Reddy, P. Hemachandra

Publication type:

Article

Therapeutics of Alzheimer's Disease: Recent Developments.

Published in:

Antioxidants, 2022, v. 11, n. 12, p. 2402, doi. 10.3390/antiox11122402

By:

Burns, Scott;
Selman, Ashley;
Sehar, Ujala;
Rawat, Priyanka;
Reddy, Arubala P.;
Reddy, P. Hemachandra

Publication type:

Article

Defective Autophagy and Mitophagy in Aging and Alzheimer's Disease.

Published in:

Frontiers in Neuroscience, 2021, p. N.PAG, doi. 10.3389/fnins.2020.612757

By:

Tran, Michael;
Reddy, P. Hemachandra

Publication type:

Article

Advancing Cancer Immunotherapy: The Potential of mRNA Vaccines As a Promising Therapeutic Approach.

Published in:

Advanced Therapeutics, 2024, v. 7, n. 2, p. 1, doi. 10.1002/adtp.202300255

By:

Goyal, Falak;
Chattopadhyay, Anandini;
Navik, Umashanker;
Jain, Aklank;
Reddy, P. Hemachandra;
Bhatti, Gurjit Kaur;
Bhatti, Jasvinder Singh

Publication type:

Article

Exploring the Complex Relationship between Diabetes and Cardiovascular Complications: Understanding Diabetic Cardiomyopathy and Promising Therapies.

Published in:

Biomedicines, 2023, v. 11, n. 4, p. 1126, doi. 10.3390/biomedicines11041126

By:

Ghosh, Nilanjan;
Chacko, Leena;
Bhattacharya, Hiranmoy;
Vallamkondu, Jayalakshmi;
Nag, Sagnik;
Dey, Abhijit;
Karmakar, Tanushree;
Reddy, P. Hemachandra;
Kandimalla, Ramesh;
Dewanjee, Saikat

Publication type:

Article

Hormonal and Genetic Regulatory Events in Breast Cancer and Its Therapeutics: Importance of the Steroidogenic Acute Regulatory Protein.

Published in:

Biomedicines, 2022, v. 10, n. 6, p. 1313, doi. 10.3390/biomedicines10061313

By:

Manna, Pulak R.;
Ahmed, Ahsen U.;
Molehin, Deborah;
Narasimhan, Madhusudhanan;
Pruitt, Kevin;
Reddy, P. Hemachandra

Publication type:

Article

Counting on COVID-19 Vaccine: Insights into the Current Strategies, Progress and Future Challenges.

Published in:

Biomedicines, 2021, v. 9, n. 11, p. 1740, doi. 10.3390/biomedicines9111740

By:

Kandimalla, Ramesh;
Chakraborty, Pratik;
Vallamkondu, Jayalakshmi;
Chaudhary, Anupama;
Samanta, Sonalinandini;
Reddy, P. Hemachandra;
De Feo, Vincenzo;
Dewanjee, Saikat

Publication type:

Article

Mitochondria in Aging and Alzheimer's Disease: Focus on Mitophagy.

Published in:

Neuroscientist, 2024, v. 30, n. 4, p. 440, doi. 10.1177/10738584221139761

By:

Pradeepkiran, Jangampalli Adi;
Baig, Javaria;
Seman, Ashley;
Reddy, P. Hemachandra

Publication type:

Article

Correction: Reddy et al. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights. Cells 2023, 12 , 1646.

Published in:

2024

By:

Reddy, P. Hemachandra;
Kshirsagar, Sudhir;
Bose, Chhanda;
Pradeepkiran, Jangampalli Adi;
Hindle, Ashly;
Singh, Sharda P.;
Reddy, Arubala P.;
Baig, Javaria

Publication type:

Correction Notice

Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights.

Published in:

Cells (2073-4409), 2023, v. 12, n. 12, p. 1646, doi. 10.3390/cells12121646

By:

Reddy, P. Hemachandra;
Kshirsagar, Sudhir;
Bose, Chhanda;
Pradeepkiran, Jangampalli Adi;
Hindle, Ashly;
Singh, Sharda P.;
Reddy, Arubala P.;
Baig, Javaria

Publication type:

Article

A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer's Disease.

Published in:

Cells (2073-4409), 2022, v. 11, n. 17, p. 2660, doi. 10.3390/cells11172660

By:

Kshirsagar, Sudhir;
Alvir, Rainier Vladlen;
Pradeepkiran, Jangampalli Adi;
Hindle, Ashly;
Vijayan, Murali;
Ramasubramaniam, Bhagavathi;
Kumar, Subodh;
Reddy, Arubala P.;
Reddy, P. Hemachandra

Publication type:

Article

Protective Effects of Chaya against Mitochondrial and Synaptic Toxicities in the Type 2 Diabetes Mouse Model TallyHO.

Published in:

Cells (2073-4409), 2022, v. 11, n. 4, p. 744, doi. 10.3390/cells11040744

By:

Ramasubramanian, Bhagavathi;
Griffith, Cameron;
Hanson, Madison;
Bunquin, Lloyd E.;
Reddy, Arubala P.;
Hegde, Vijay;
Reddy, P. Hemachandra

Publication type:

Article

Early Cellular, Molecular, Morphological and Behavioral Changes in the Humanized Amyloid-Beta-Knock-In Mouse Model of Late-Onset Alzheimer's Disease.

Published in:

Cells (2073-4409), 2022, v. 11, n. 4, p. 733, doi. 10.3390/cells11040733

By:

Kshirsagar, Sudhir;
Alvir, Rainier Vladlen;
Hindle, Ashly;
Kumar, Subodh;
Vijayan, Murali;
Pradeepkiran, Jangampalli Adi;
Reddy, Arubala P.;
Ramasubramanian, Bhagavathi;
Reddy, P. Hemachandra

Publication type:

Article

COVID-19 and Rheumatoid Arthritis Crosstalk: Emerging Association, Therapeutic Options and Challenges.

Published in:

Cells (2073-4409), 2021, v. 10, n. 12, p. 3291, doi. 10.3390/cells10123291

By:

Dewanjee, Saikat;
Kandimalla, Ramesh;
Kalra, Rajkumar Singh;
Valupadas, Chandrasekhar;
Vallamkondu, Jayalakshmi;
Kolli, Viswakalyan;
Dey Ray, Sarbani;
Reddy, Arubala P.;
Reddy, P. Hemachandra

Publication type:

Article

RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer's Disease.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 3113, doi. 10.3390/cells10113113

By:

Awasthi, Sanjay;
Hindle, Ashly;
Sawant, Neha A.;
George, Mathew;
Vijayan, Murali;
Kshirsagar, Sudhir;
Morton, Hallie;
Bunquin, Lloyd E.;
Palade, Philip T.;
Lawrence, J. Josh;
Khan, Hafiz;
Bose, Chhanda;
Reddy, P. Hemachandra;
Singh, Sharda P.

Publication type:

Article

The Potential Role of Cytokines and Growth Factors in the Pathogenesis of Alzheimer's Disease.

Published in:

Cells (2073-4409), 2021, v. 10, n. 10, p. 2790, doi. 10.3390/cells10102790

By:

Ogunmokun, Gilbert;
Dewanjee, Saikat;
Chakraborty, Pratik;
Valupadas, Chandrasekhar;
Chaudhary, Anupama;
Kolli, Viswakalyan;
Anand, Uttpal;
Vallamkondu, Jayalakshmi;
Goel, Parul;
Paluru, Hari Prasad Reddy;
Gill, Kiran Dip;
Reddy, P. Hemachandra;
De Feo, Vincenzo;
Kandimalla, Ramesh

Publication type:

Article

The Emerging Role of HDACs: Pathology and Therapeutic Targets in Diabetes Mellitus.

Published in:

Cells (2073-4409), 2021, v. 10, n. 6, p. 1340, doi. 10.3390/cells10061340

By:

Dewanjee, Saikat;
Vallamkondu, Jayalakshmi;
Kalra, Rajkumar Singh;
Chakraborty, Pratik;
Gangopadhyay, Moumita;
Sahu, Ranabir;
Medala, Vijaykrishna;
John, Albin;
Reddy, P. Hemachandra;
De Feo, Vincenzo;
Kandimalla, Ramesh

Publication type:

Article

All-Trans Retinoic Acid Increases DRP1 Levels and Promotes Mitochondrial Fission.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1202, doi. 10.3390/cells10051202

By:

Chidipi, Bojjibabu;
Shah, Syed Islamuddin;
Reiser, Michelle;
Kanithi, Manasa;
Garces, Amanda;
Cha, Byeong J.;
Ullah, Ghanim;
Noujaim, Sami F.;
Reddy, P. Hemachandra

Publication type:

Article

Mitochondrial MicroRNAs in Aging and Neurodegenerative Diseases.

Published in:

Cells (2073-4409), 2020, v. 9, n. 6, p. 1345, doi. 10.3390/cells9061345

By:

John, Albin;
Kubosumi, Aaron;
Reddy, P. Hemachandra

Publication type:

Article

Dynamics of Dynamin-Related Protein 1 in Alzheimer's Disease and Other Neurodegenerative Diseases.

Published in:

Cells (2073-4409), 2019, v. 8, n. 9, p. 961, doi. 10.3390/cells8090961

By:

Oliver, Darryll;
Reddy, P. Hemachandra

Publication type:

Article

Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer's Disease.

Published in:

Cells (2073-4409), 2019, v. 8, n. 5, p. 488, doi. 10.3390/cells8050488

By:

Reddy, P. Hemachandra;
Oliver, Darryll MA

Publication type:

Article

Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer's Disease.

Published in:

Cells (2073-4409), 2019, v. 8, n. 3, p. 260, doi. 10.3390/cells8030260

By:

Pradeepkiran, Jangampalli Adi;
Reddy, P. Hemachandra

Publication type:

Article

Neurotransmitter CART as a New Therapeutic Candidate for Parkinson's Disease.

Published in:

Pharmaceuticals (14248247), 2013, v. 6, n. 1, p. 108, doi. 10.3390/ph6010108

By:

Peizhong Mao;
Meshul, Charles K.;
Thuillier, Philippe;
Hemachandra Reddy, P.

Publication type:

Article

Amyloid Beta and MicroRNAs in Alzheimer’s Disease.

Published in:

Frontiers in Neuroscience, 2019, p. 1, doi. 10.3389/fnins.2019.00430

By:

Amakiri, Nnana;
Kubosumi, Aaron;
Tran, James;
Reddy, P. Hemachandra

Publication type:

Article

Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.

Published in:

Nature Genetics, 1998, v. 20, n. 2, p. 198, doi. 10.1038/2510

By:

Reddy, P. Hemachandra;
Williams, Maya;
Charles, Vinod;
Garrett, Lisa;
Pike-Buchanan, Lisa;
Whetsell, William O.;
Miller, Georgina;
Tagle, Danilo A.

Publication type:

Article

partial reduction of Drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic Tau mouse model of Alzheimer disease.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 11, p. 1788, doi. 10.1093/hmg/ddab360

By:

Kandimalla, Ramesh;
Manczak, Maria;
Pradeepkiran, Jangampalli Adi;
Morton, Hallie;
Reddy, P Hemachandra

Publication type:

Article

Protective effects of a small-molecule inhibitor DDQ against tau-induced toxicities in a transgenic tau mouse model of Alzheimer's disease.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 7, p. 1022, doi. 10.1093/hmg/ddab285

By:

Vijayan, Murali;
George, Mathew;
Bunquin, Lloyd E;
Bose, Chhanda;
Reddy, P Hemachandra

Publication type:

Article

Protective effects of mitophagy enhancers against amyloid beta-induced mitochondrial and synaptic toxicities in Alzheimer disease.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 3, p. 423, doi. 10.1093/hmg/ddab262

By:

Kshirsagar, Sudhir;
Sawant, Neha;
Morton, Hallie;
Reddy, Arubala P;
Reddy, P Hemachandra

Publication type:

Article

Protective effects of a small molecule inhibitor ligand against hyperphosphorylated tau-induced mitochondrial and synaptic toxicities in Alzheimer disease.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 2, p. 244, doi. 10.1093/hmg/ddab244

By:

Pradeepkiran, Jangampalli Adi;
Munikumar, Manne;
Reddy, Arubala P;
Reddy, P Hemachandra

Publication type:

Article

Protective effects of antidepressant citalopram against abnormal APP processing and amyloid beta-induced mitochondrial dynamics, biogenesis, mitophagy and synaptic toxicities in Alzheimer's disease.

Published in:

Human Molecular Genetics, 2021, v. 30, n. 10, p. 847, doi. 10.1093/hmg/ddab054

By:

Reddy, Arubala P;
Yin, Xiangling;
Sawant, Neha;
Reddy, P Hemachandra

Publication type:

Article

Selective serotonin reuptake inhibitor citalopram ameliorates cognitive decline and protects against amyloid beta-induced mitochondrial dynamics, biogenesis, autophagy, mitophagy and synaptic toxicities in a mouse model of Alzheimer's disease.

Published in:

Human Molecular Genetics, 2021, v. 30, n. 9, p. 789, doi. 10.1093/hmg/ddab091

By:

Reddy, Arubala P;
Sawant, Neha;
Morton, Hallie;
Kshirsagar, Sudhir;
Bunquin, Lloyd E;
Yin, Xiangling;
Reddy, P Hemachandra

Publication type:

Article

Effects of Lipotoxicity in Brain Microvascular Endothelial Cells During Sirt3 Deficiency-Potential Role in Comorbid Alzheimer's Disease.

Published in:

Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.716616

By:

Tyagi, Alpna;
Mirita, Carol;
Shah, Iman;
Reddy, P. Hemachandra;
Pugazhenthi, Subbiah

Publication type:

Article

Impact of COVID-19 on Mitochondrial-Based Immunity in Aging and Age-Related Diseases.

Published in:

Frontiers in Aging Neuroscience, 2021, v. 12, p. N.PAG, doi. 10.3389/fnagi.2020.614650

By:

Ganji, Riya;
Reddy, P. Hemachandra

Publication type:

Article

Role of mitochondria in neurodegenerative diseases: mitochondria as a therapeutic target in Alzheimer's disease.

Published in:

2009

By:

Reddy PH;
Reddy, P Hemachandra

Publication type:

journal article

Acetylation of Steroidogenic Acute Regulatory Protein Sensitizes 17β-Estradiol Regulation in Hormone-Sensitive Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8732, doi. 10.3390/ijms25168732

By:

Manna, Pulak R.;
Molehin, Deborah;
Ahmed, Ahsen U.;
Yang, Shengping;
Reddy, P. Hemachandra

Publication type:

Article

Epigenetic Dysregulation and Its Correlation with the Steroidogenic Machinery Impacting Breast Pathogenesis: Data Mining and Molecular Insights into Therapeutics.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 22, p. 16488, doi. 10.3390/ijms242216488

By:

Manna, Pulak R.;
Yang, Shengping;
Reddy, P. Hemachandra

Publication type:

Article

Support Provided by Caregivers for Community-Dwelling Diabetic Hispanic Adults with Intellectual Disabilities and Comorbid Conditions.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3848, doi. 10.3390/ijms24043848

By:

Rawat, Priyanka;
Sehar, Ujala;
Bisht, Jasbir;
Reddy, P. Hemachandra

Publication type:

Article

Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 758, doi. 10.3390/ijms24010758

By:

Manna, Pulak R.;
Ramachandran, Sabarish;
Pradeepkiran, Jangampalli Adi;
Molehin, Deborah;
Castro-Piedras, Isabel;
Pruitt, Kevin;
Ganapathy, Vadivel;
Reddy, P. Hemachandra

Publication type:

Article

Amyloid Beta in Aging and Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 12924, doi. 10.3390/ijms232112924

By:

Sehar, Ujala;
Rawat, Priyanka;
Reddy, Arubala P.;
Kopel, Jonathan;
Reddy, P. Hemachandra

Publication type:

Article

Phosphorylated Tau in Alzheimer's Disease and Other Tauopathies.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 12841, doi. 10.3390/ijms232112841

By:

Rawat, Priyanka;
Sehar, Ujala;
Bisht, Jasbir;
Selman, Ashley;
Culberson, John;
Reddy, P. Hemachandra

Publication type:

Article

The Role of Obesity and Diabetes in Dementia.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9267, doi. 10.3390/ijms23169267

By:

Selman, Ashley;
Burns, Scott;
Reddy, Arubala P.;
Culberson, John;
Reddy, P. Hemachandra

Publication type:

Article

Reduced VDAC1, Maintained Mitochondrial Dynamics and Enhanced Mitochondrial Biogenesis in a Transgenic Tau Mouse Model of Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8561, doi. 10.3390/ijms23158561

By:

Vijayan, Murali;
Reddy, P. Hemachandra

Publication type:

Article

Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer's Disease?

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 11, p. 6098, doi. 10.3390/ijms23116098

By:

Hindle, Ashly;
Singh, Sharda P.;
Pradeepkiran, Jangampalli Adi;
Bose, Chhanda;
Vijayan, Murali;
Kshirsagar, Sudhir;
Sawant, Neha A.;
Reddy, P. Hemachandra

Publication type:

Article

Behavioral Evidence for a Tau and HIV-gp120 Interaction.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5514, doi. 10.3390/ijms23105514

By:

Vijayan, Murali;
Yin, Linda;
Reddy, P. Hemachandra;
Benamar, Khalid

Publication type:

Article

Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.

Published in:

Human Molecular Genetics, 2006, v. 15, n. 9, p. 1437, doi. 10.1093/hmg/ddl066

By:

Manczak, Maria;
Anekonda, Thimmappa S.;
Henson, Edward;
Park, Byung S.;
Quinn, Joseph;
Reddy, P. Hemachandra

Publication type:

Article

Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease.

Published in:

Human Molecular Genetics, 2004, v. 13, n. 12, p. 1225, doi. 10.1093/hmg/ddh140

By:

Reddy, P. Hemachandra;
McWeeney, Shannon;
Park, Byung S.;
Manczak, Maria;
Gutala, Ramana V.;
Partovi, Dara;
Jung, Youngsin;
Yau, Vincent;
Searles, Robert;
Mori, Motomi;
Quinn, Joseph

Publication type:

Article

Lifestyle Modifications and Nutritional Interventions in Aging-Associated Cognitive Decline and Alzheimer's Disease.

Published in:

Frontiers in Aging Neuroscience, 2020, v. 11, p. 1, doi. 10.3389/fnagi.2019.00369

By:

Bhatti, Gurjit Kaur;
Reddy, Arubala P.;
Reddy, P. Hemachandra;
Bhatti, Jasvinder Singh

Publication type:

Article

The COVID-19 Effect on the Immune System and Mitochondrial Dynamics in Diabetes, Obesity, and Dementia.

Published in:

Neuroscientist, 2021, v. 27, n. 4, p. 331, doi. 10.1177/1073858420960443

By:

Holder, Katherine;
Reddy, P. Hemachandra

Publication type:

Article

Cell-Free DNA As Peripheral Biomarker of Alzheimer's Disease.

Published in:

Aging & Disease, 2025, v. 16, n. 2, p. 787, doi. 10.14336/AD.2024.0329

By:

Khemka, Sachi;
Sehar, Ujala;
Manna, Pulak R.;
Kshirsagar, Sudhir;
Reddy, P. Hemachandra

Publication type:

Article