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Enhancing gene editing specificity by attenuating DNA cleavage kinetics.
- Published in:
- Nature Biotechnology, 2019, v. 37, n. 8, p. 945, doi. 10.1038/s41587-019-0186-z
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- Article
Diversifying the structure of zinc finger nucleases for high-precision genome editing.
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- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08867-x
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- Article
Mammalian interspecies substitution of immune modulatory alleles by genome editing.
- Published in:
- Scientific Reports, 2016, p. 21645, doi. 10.1038/srep21645
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- Article
Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application.
- Published in:
- Scientific Reports, 2016, p. 21757, doi. 10.1038/srep21757
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- Article
Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing.
- Published in:
- Nature Communications, 2016, v. 7, n. 1, p. 10194, doi. 10.1038/ncomms10194
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- Publication type:
- Article
Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.
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- Molecular Therapy, 2015, v. 23, n. 8, p. 1380, doi. 10.1038/mt.2015.71
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- Publication type:
- Article
Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.
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- EMBO Molecular Medicine, 2014, v. 6, n. 4, p. 458, doi. 10.1002/emmm.201303672
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- Article
Translating dosage compensation to trisomy 21.
- Published in:
- Nature, 2013, v. 500, n. 7462, p. 296, doi. 10.1038/nature12394
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- Article
Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.
- Published in:
- Nature Methods, 2012, v. 9, n. 10, p. 993, doi. 10.1038/nmeth.2143
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- Publication type:
- Article
Transcriptional activation of Brassica napusβ-ketoacyl-ACP synthase II with an engineered zinc finger protein transcription factor.
- Published in:
- Plant Biotechnology Journal, 2012, v. 10, n. 7, p. 783, doi. 10.1111/j.1467-7652.2012.00695.x
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- Article
A Designed Zinc-finger Transcriptional Repressor of Phospholamban Improves Function of the Failing Heart.
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- Molecular Therapy, 2012, v. 20, n. 8, p. 1508, doi. 10.1038/mt.2012.80
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- Article
Genetic engineering of human pluripotent cells using TALE nucleases.
- Published in:
- Nature Biotechnology, 2011, v. 29, n. 8, p. 731, doi. 10.1038/nbt.1927
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- Article
In vivo genome editing restores haemostasis in a mouse model of haemophilia.
- Published in:
- Nature, 2011, v. 475, n. 7355, p. 217, doi. 10.1038/nature10177
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- Publication type:
- Article
DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation.
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- PLoS Genetics, 2011, v. 7, n. 6, p. 1, doi. 10.1371/journal.pgen.1002080
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- Article
Engineering HIV-Resistant Human CD4+ T Cells with CXCR4-Specific Zinc-Finger Nucleases.
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- PLoS Pathogens, 2011, v. 7, n. 4, p. 1, doi. 10.1371/journal.ppat.1002020
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- Article
Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells.
- Published in:
- Nature Cell Biology, 2011, v. 13, n. 3, p. 331, doi. 10.1038/ncb2175
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- Article
A TALE nuclease architecture for efficient genome editing.
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- Nature Biotechnology, 2011, v. 29, n. 2, p. 143, doi. 10.1038/nbt.1755
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- Publication type:
- Article
An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 49, p. 16469, doi. 10.1523/JNEUROSCI.2440-10.2010
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- Publication type:
- Article
An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 48, p. 16469, doi. 10.1523/JNEUROSCI.2440-10.2010
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- Publication type:
- Article
Genome editing with engineered zinc finger nucleases.
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- 2010
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- Publication type:
- journal article
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.
- Published in:
- Nature Biotechnology, 2009, v. 27, n. 9, p. 851, doi. 10.1038/nbt.1562
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- Publication type:
- Article
Establishment of HIV-1 resistance in CD4<sup>+</sup> T cells by genome editing using zinc-finger nucleases.
- Published in:
- Nature Biotechnology, 2008, v. 26, n. 7, p. 808, doi. 10.1038/nbt1410
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- Publication type:
- Article
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases.
- Published in:
- Nature Biotechnology, 2008, v. 26, n. 6, p. 702, doi. 10.1038/nbt1409
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- Publication type:
- Article
Enhanced protein production by engineered zinc finger proteins.
- Published in:
- Biotechnology & Bioengineering, 2007, v. 97, n. 5, p. 1180, doi. 10.1002/bit.21304
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- Publication type:
- Article
An improved zinc-finger nuclease architecture for highly specific genome editing.
- Published in:
- Nature Biotechnology, 2007, v. 25, n. 7, p. 778, doi. 10.1038/nbt1319
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- Article
387. Advantageous Properties of the piggyBac Transposon System for Gene Transfer in Human Cells.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S147, doi. 10.1016/j.ymthe.2006.08.448
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- Publication type:
- Article
555. Large-Scale, Flow-Based Electroporation To Deliver Engineered Zinc Finger Protein Nucleases That Mediate High-Efficiency Disruption of the Human CCR5 Gene.
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- Molecular Therapy, 2006, v. 13, p. S214, doi. 10.1016/j.ymthe.2006.08.627
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- Publication type:
- Article
758. Towards Gene Knock out Therapy for AIDS/HIV: Targeted Disruption of CCR5 Using Engineered Zinc Finger Protein Nucleases (ZFNs).
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- Molecular Therapy, 2006, v. 13, p. S293, doi. 10.1016/j.ymthe.2006.08.842
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- Publication type:
- Article
787. Engineered Fok I Heterodimers for Enhanced Zinc Finger Nuclease Specificity.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S305, doi. 10.1016/j.ymthe.2006.08.875
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- Publication type:
- Article
Gene Transfer of an Engineered Transcription Factor Promoting Expression of VEGF-A Protects Against Experimental Diabetic Neuropathy.
- Published in:
- Diabetes, 2006, v. 55, n. 6, p. 1847, doi. 10.2337/db05-1060
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- Publication type:
- Article
43. Targeting the Biology of Heart Disease: Engineered Zinc Finger Protein Repressors of Phospholamban as a Potential Therapy for Congestive Heart Failure
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- 2005
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- Publication type:
- Abstract
85. Development of Zinc Finger Nucleases for Therapeutic Gene Correction of Sickle Cell Anemia
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- 2005
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- Publication type:
- Abstract
379. New Zinc Finger Protein Nuclease Architectures for More Efficient Gene Modification Therapies
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- 2005
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- Publication type:
- Abstract
974. Towards Gene Knock out Therapy for AIDS/HIV: Targeted Disruption of CCR5 Using Engineered Zinc Finger Protein Nucleases (ZFNs)
- Published in:
- 2005
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- Publication type:
- Abstract
1072. Superactivation of the SRα and CMV Promoters Using Designed Zinc Finger Proteins
- Published in:
- 2005
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- Publication type:
- Abstract
Induction of angiogenesis in a mouse model using engineered transcription factors.
- Published in:
- Nature Medicine, 2002, v. 8, n. 12, p. 1427, doi. 10.1038/nm1202-795
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- Publication type:
- Article
Designed transcription factors as structural, functional and therapeutic probes of chromatin in vivo.
- Published in:
- EMBO Reports, 2002, v. 3, n. 7, p. 610, doi. 10.1093/embo-reports/kvf140
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- Publication type:
- Article