Works by Rautio, Jarkko

Results: 27

Formulating Resveratrol and Melatonin Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Ocular Administration Using Design of Experiments.

Published in:

Pharmaceutics, 2024, v. 16, n. 1, p. 125, doi. 10.3390/pharmaceutics16010125

By:

Zingale, Elide;
Bonaccorso, Angela;
D'Amico, Agata Grazia;
Lombardo, Rosamaria;
D'Agata, Velia;
Rautio, Jarkko;
Pignatello, Rosario

Publication type:

Article

Amino Acid-Based Boron Carriers in Boron Neutron Capture Therapy (BNCT).

Published in:

Pharmaceutics, 2023, v. 15, n. 12, p. 2663, doi. 10.3390/pharmaceutics15122663

By:

Järvinen, Juulia;
Pulkkinen, Herkko;
Rautio, Jarkko;
Timonen, Juri M.

Publication type:

Article

Development of Lyophilised Eudragit ® Retard Nanoparticles for the Sustained Release of Clozapine via Intranasal Administration.

Published in:

Pharmaceutics, 2023, v. 15, n. 5, p. 1554, doi. 10.3390/pharmaceutics15051554

By:

Lombardo, Rosamaria;
Ruponen, Marika;
Rautio, Jarkko;
Ghelardini, Carla;
Di Cesare Mannelli, Lorenzo;
Calosi, Laura;
Bani, Daniele;
Lampinen, Riikka;
Kanninen, Katja M.;
Koivisto, Anne M.;
Penttilä, Elina;
Löppönen, Heikki;
Pignatello, Rosario

Publication type:

Article

Intranasal Nanoemulsions for Direct Nose-to-Brain Delivery of Actives for CNS Disorders.

Published in:

Pharmaceutics, 2020, v. 12, n. 12, p. 1230, doi. 10.3390/pharmaceutics12121230

By:

Bahadur, Shiv;
Pardhi, Dinesh M.;
Rautio, Jarkko;
Rosenholm, Jessica M.;
Pathak, Kamla

Publication type:

Article

Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS).

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 265, doi. 10.3390/ph18020265

By:

Zingale, Elide;
Masuzzo, Sebastiano;
Lajunen, Tatu;
Reinisalo, Mika;
Rautio, Jarkko;
Consoli, Valeria;
D'Amico, Agata Grazia;
Vanella, Luca;
Pignatello, Rosario

Publication type:

Article

Development of Sesamol Carbamate-L-Phenylalanine Prodrug Targeting L-Type Amino Acid Transporter1 (LAT1) as a Potential Antiproliferative Agent against Melanoma.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8446, doi. 10.3390/ijms23158446

By:

Srisongkram, Tarapong;
Bahrami, Katayun;
Järvinen, Juulia;
Timonen, Juri;
Rautio, Jarkko;
Weerapreeyakul, Natthida

Publication type:

Article

Tyrosine–Chlorambucil Conjugates Facilitate Cellular Uptake through L-Type Amino Acid Transporter 1 (LAT1) in Human Breast Cancer Cell Line MCF-7.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 6, p. 2132, doi. 10.3390/ijms21062132

By:

Pocasap, Piman;
Weerapreeyakul, Natthida;
Timonen, Juri;
Järvinen, Juulia;
Leppänen, Jukka;
Kärkkäinen, Jussi;
Rautio, Jarkko

Publication type:

Article

Prodrug Approaches for CNS Delivery.

Published in:

AAPS Journal, 2008, v. 10, n. 1, p. 92, doi. 10.1208/s12248-008-9009-8

By:

Rautio, Jarkko;
Laine, Krista;
Gynther, Mikko;
Savolainen, Jouko

Publication type:

Article

Design, Synthesis and Brain Uptake of LAT1-Targeted Amino Acid Prodrugs of Dopamine.

Published in:

Pharmaceutical Research, 2013, v. 30, n. 10, p. 2523, doi. 10.1007/s11095-012-0966-3

By:

Peura, Lauri;
Malmioja, Kalle;
Huttunen, Kristiina;
Leppänen, Jukka;
Hämäläinen, Miia;
Forsberg, Markus;
Rautio, Jarkko;
Laine, Krista

Publication type:

Article

Erratum to: Design, Synthesis and Brain Uptake of LAT1-Targeted Amino Acid Prodrugs of Dopamine.

Published in:

2013

By:

Peura, Lauri;
Malmioja, Kalle;
Huttunen, Kristiina;
Leppänen, Jukka;
Hämäläinen, Miia;
Forsberg, Markus;
Gynther, Mikko;
Rautio, Jarkko;
Laine, Krista

Publication type:

Correction Notice

Novel Cyclic Phosphate Prodrug Approach for Cytochrome P450-activated Drugs Containing an Alcohol Functionality.

Published in:

Pharmaceutical Research, 2007, v. 24, n. 4, p. 679, doi. 10.1007/s11095-006-9187-y

By:

Kristiina Huttunen;
Niina Mähönen;
Jukka Leppänen;
Jouko Vepsäläinen;
Risto Juvonen;
Hannu Raunio;
Hanna Kumpulainen;
Tomi Järvinen;
Jarkko Rautio

Publication type:

Article

Amino Acid Promoieties Alter Valproic Acid Pharmacokinetics and Enable Extended Brain Exposure.

Published in:

Neurochemical Research, 2016, v. 41, n. 10, p. 2797, doi. 10.1007/s11064-016-1996-8

By:

Gynther, Mikko;
Peura, Lauri;
Vernerová, Monika;
Leppänen, Jukka;
Kärkkäinen, Jussi;
Lehtonen, Marko;
Rautio, Jarkko;
Huttunen, Kristiina

Publication type:

Article

Quantitative Insight into the Design of Compounds Recognized by the L-Type Amino Acid Transporter 1 (LAT1).

Published in:

ChemMedChem, 2014, v. 9, n. 12, p. 2699, doi. 10.1002/cmdc.201402281

By:

Ylikangas, Henna;
Malmioja, Kalle;
Peura, Lauri;
Gynther, Mikko;
Nwachukwu, Emmanuel O.;
Leppänen, Jukka;
Laine, Krista;
Rautio, Jarkko;
Lahtela‐Kakkonen, Maija;
Huttunen, Kristiina M.;
Poso, Antti

Publication type:

Article

A novel D2-dopaminergic and α2-adrenoceptor receptor agonist induces substantial and prolonged IOP decrease in normotensive rabbits.

Published in:

Journal of Pharmacy & Pharmacology, 2003, v. 55, n. 6, p. 789

By:

Jouko Savolainen;
Jarkko Rautio;
Roberta Razzetti;
Tomi Järvinen

Publication type:

Article

Prodrugs: design and clinical applications.

Published in:

Nature Reviews Drug Discovery, 2008, v. 7, n. 3, p. 255, doi. 10.1038/nrd2468

By:

Rautio, Jarkko;
Kumpulainen, Hanna;
Heimbach, Tycho;
Oliyai, Reza;
Oh, Dooman;
Järvinen, Tomi;
Savolainen, Jouko

Publication type:

Article

Diclofenac readily penetrates the cerebrospinal fluid in children.

Published in:

British Journal of Clinical Pharmacology, 2008, v. 65, n. 6, p. 879, doi. 10.1111/j.1365-2125.2008.03126.x

By:

Kokki, Hannu;
Kumpulainen, Elina;
Laisalmi, Merja;
Savolainen, Jouko;
Rautio, Jarkko;
Lehtonen, Marko

Publication type:

Article

Plasma and Cerebrospinal Fluid Concentrations of Indomethacin in Children After Intravenous Administration.

Published in:

Journal of Clinical Pharmacology, 2007, v. 47, n. 1, p. 94, doi. 10.1177/0091270006295202

By:

Anne AM Mannila;
Elina EK Kumpulainen;
Marko ML Lehtonen;
Marja MH Heikkinen;
Merja ML Laisalmi;
Terhi TS Salo;
Jarkko JR Rautio;
Jouko JS Savolainen;
Hannu HK Kokki

Publication type:

Article

Aminocarbonyloxymethyl Ester Prodrugs of Flufenamic Acid and Diclofenac: Suppressing the Rearrangement Pathway in Aqueous Media.

Published in:

Archiv der Pharmazie, 2007, v. 340, n. 1, p. 32, doi. 10.1002/ardp.200600145

By:

Lina Ribeiro;
Nuno Silva;
Jim Iley;
Jarkko Rautio;
Tomi Järvinen;
Hélder Mota-Filipe;
Rui Moreira

Publication type:

Article

Towards New Delivery Agents for Boron Neutron Capture Therapy: Synthesis and In Vitro Evaluation of a Set of Fluorinated Carbohydrate Derivatives.

Published in:

Molecules, 2024, v. 29, n. 17, p. 4263, doi. 10.3390/molecules29174263

By:

Matović, Jelena;
Järvinen, Juulia;
Sokka, Iris K.;
Imlimthan, Surachet;
Aitio, Olli;
Sarparanta, Mirkka;
Rautio, Jarkko;
Ekholm, Filip S.

Publication type:

Article

Effects of Sucrose Palmitate on the Physico-Chemical and Mucoadhesive Properties of Buccal Films.

Published in:

Molecules, 2020, v. 25, n. 22, p. 5248, doi. 10.3390/molecules25225248

By:

Kelemen, András;
Katona, Bálint;
Módra, Szilvia;
Aigner, Zoltán;
Sebe, István;
Pintye-Hódi, Klára;
Zelkó, Romána;
Regdon Jr., Géza;
Kristó, Katalin;
Rautio, Jarkko

Publication type:

Article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6.

Published in:

2020

By:

Vanden Eynde, Jean Jacques;
Mangoni, Arduino A.;
Rautio, Jarkko;
Leprince, Jérôme;
Azuma, Yasu-Taka;
García-Sosa, Alfonso T.;
Hulme, Christopher;
Jampilek, Josef;
Karaman, Rafik;
Li, Wei;
Gomes, Paula A. C.;
Hadjipavlou-Litina, Dimitra;
Capasso, Raffaele;
Geronikaki, Athina;
Cerchia, Laura;
Sabatier, Jean-Marc;
Ragno, Rino;
Tuccinardi, Tiziano;
Trabocchi, Andrea;
Winum, Jean-Yves

Publication type:

Editorial

Role of L-Type Amino Acid Transporter 1 (LAT1) for the Selective Cytotoxicity of Sesamol in Human Melanoma Cells.

Published in:

Molecules, 2019, v. 24, n. 21, p. 3869, doi. 10.3390/molecules24213869

By:

Srisongkram, Tarapong;
Weerapreeyakul, Natthida;
Kärkkäinen, Jussi;
Rautio, Jarkko;
Sekeroglu, Nazim

Publication type:

Article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–5.

Published in:

Molecules, 2019, v. 24, n. 13, p. 2415, doi. 10.3390/molecules24132415

By:

Mangoni, Arduino A.;
Eynde, Jean Jacques Vanden;
Jampilek, Josef;
Hadjipavlou-Litina, Dimitra;
Liu, Hong;
Reynisson, Jóhannes;
Sousa, Maria Emília;
Gomes, Paula A. C.;
Prokai-Tatrai, Katalin;
Tuccinardi, Tiziano;
Sabatier, Jean-Marc;
Luque, F. Javier;
Rautio, Jarkko;
Karaman, Rafik;
Vasconcelos, M. Helena;
Gemma, Sandra;
Galdiero, Stefania;
Hulme, Christopher;
Collina, Simona;
Gütschow, Michael

Publication type:

Article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–4.

Published in:

2019

By:

Mangoni, Arduino A;
Guillou, Catherine;
Vanden Eynde, Jean Jacques;
Hulme, Christopher;
Jampilek, Josef;
Li, Wei;
Prokai-Tatrai, Katalin;
Rautio, Jarkko;
Collina, Simona;
Tuccinardi, Tiziano;
Sousa, Maria Emília;
Sabatier, Jean-Marc;
Galdiero, Stefania;
Karaman, Rafik;
Kokotos, George;
Torri, Giangiacomo;
Luque, F. Javier;
Vasconcelos, M. Helena;
Hadjipavlou-Litina, Dimitra;
Siciliano, Carlo

Publication type:

Editorial

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3.

Published in:

Molecules, 2018, v. 23, n. 7, p. 1596, doi. 10.3390/molecules23071596

By:

Mangoni, Arduino A.;
Tuccinardi, Tiziano;
Collina, Simona;
Vanden Eynde, Jean Jacques;
Muñoz-Torrero, Diego;
Karaman, Rafik;
Siciliano, Carlo;
de Sousa, Maria Emília;
Prokai-Tatrai, Katalin;
Rautio, Jarkko;
Guillou, Catherine;
Gütschow, Michael;
Galdiero, Stefania;
Hong Liu;
Agrofoglio, Luigi A.;
Sabatier, Jean-Marc;
Hulme, Christopher;
Kokotos, George;
Qong You;
Gomes, Paula A. C.

Publication type:

Article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-2.

Published in:

Molecules, 2018, v. 23, n. 1, p. 65, doi. 10.3390/molecules23010065

By:

Muñoz-Torrero, Diego;
Mangoni, Arduino A.;
Liu, Hong;
Hulme, Christopher;
Rautio, Jarkko;
Karaman, Rafik;
de Sousa, Maria Emília;
Prokai-Tatrai, Katalin;
Sabatier, Jean-Marc;
Siciliano, Carlo;
Luque, F. Javier;
Kokotos, George;
Ragno, Rino;
Collina, Simona;
Guillou, Catherine;
Gütschow, Michael;
Agrofoglio, Luigi A.

Publication type:

Article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes.

Published in:

2017

By:

Muñoz-Torrero, Diego;
Mangoni, Arduino A.;
Guillou, Catherine;
Collina, Simona;
Eynde, Jean Jacques Vanden;
Rautio, Jarkko;
Keserű, György M.;
Hulme, Christopher;
Chibale, Kelly;
Luque, F. Javier;
Karaman, Rafik;
Gütschow, Michael;
Hong Liu;
Ragno, Rino

Publication type:

Abstract