Works by Raunio, Hannu

Results: 29

Use of an online surveillance system for screening drug interactions in prescriptions in community pharmacies.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 8, p. 661, doi. 10.1007/s00228-006-0149-4

By:

Heikkilä, Tiina;
Lekander, Tuula;
Raunio, Hannu

Publication type:

Article

Pinoresinol stimulates keratinocyte proliferation and downregulates TNF‐α secretion in peripheral blood mononuclear cells: An experimental in vitro study.

Published in:

Health Science Reports, 2023, v. 6, n. 1, p. 1, doi. 10.1002/hsr2.998

By:

Haapakorva, Elias;
Raunio, Hannu;
von Wright, Atte;
Harvima, Ilkka

Publication type:

Article

Molecular docking and oxidation kinetics of 3-phenyl coumarin derivatives by human CYP2A13.

Published in:

Xenobiotica, 2021, v. 51, n. 11, p. 1207, doi. 10.1080/00498254.2021.1898700

By:

Juvonen, Risto O.;
Jokinen, Elmeri M.;
Huuskonen, Juhani;
Kärkkäinen, Olli;
Raunio, Hannu;
Pentikäinen, Olli T.

Publication type:

Article

In vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species.

Published in:

Xenobiotica, 2020, v. 50, n. 8, p. 885, doi. 10.1080/00498254.2020.1711544

By:

Juvonen, Risto O.;
Pentikäinen, Olli;
Huuskonen, Juhani;
Timonen, Juri;
Kärkkäinen, Olli;
Heikkinen, Aki;
Fashe, Muluneh;
Raunio, Hannu

Publication type:

Article

Development of new Coumarin-based profluorescent substrates for human cytochrome P450 enzymes.

Published in:

Xenobiotica, 2019, v. 49, n. 9, p. 1015, doi. 10.1080/00498254.2018.1530399

By:

Juvonen, Risto O.;
Raunio, Hannu;
Ahinko, Mira;
Pentikäinen, Olli T.;
Huuskonen, Juhani

Publication type:

Article

Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes.

Published in:

Frontiers in Pharmacology, 2015, p. 1, doi. 10.3389/fphar.2015.00123

By:

Raunio, Hannu;
Kuusisto, Mira;
Juvonen, Risto O.;
Pentikäinen, Olli T.;
Fourches, Denis;
Mumtaz, Moiz M.

Publication type:

Article

Inhibition of human CYP1 enzymes by a classical inhibitor α‐naphthoflavone and a novel inhibitor N‐(3, 5‐dichlorophenyl)cyclopropanecarboxamide: An in vitro and in silico study.

Published in:

Chemical Biology & Drug Design, 2020, v. 95, n. 5, p. 520, doi. 10.1111/cbdd.13669

By:

Juvonen, Risto Olavi;
Jokinen, Elmeri Matias;
Javaid, Adeel;
Lehtonen, Marko;
Raunio, Hannu;
Pentikäinen, Olli Taneli

Publication type:

Article

Accelerated apoptosis and low Bcl-2 expression associated with neuroendocrine differentiation predict shortened survival in operated large cell carcinoma of the lung.

Published in:

Pathology & Oncology Research, 1999, v. 5, n. 3, p. 179, doi. 10.1053/paor.1999.0198

By:

Eerola, Anna-Kaisa;
Ruokolainen, Henni;
Soini, Ylermi;
Raunio, Hannu;
PÄÄKKÖ, Paavo

Publication type:

Article

Blocking oestradiol synthesis pathways with potent and selective coumarin derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 743, doi. 10.1080/14756366.2018.1452919

By:

Niinivehmas, Sanna;
Postila, Pekka A.;
Rauhamäki, Sanna;
Manivannan, Elangovan;
Kortet, Sami;
Ahinko, Mira;
Huuskonen, Pasi;
Nyberg, Niina;
Koskimies, Pasi;
Lätti, Sakari;
Multamäki, Elina;
Juvonen, Risto O.;
Raunio, Hannu;
Pasanen, Markku;
Huuskonen, Juhani;
Pentikäinen, Olli T.

Publication type:

Article

Independent Induction and Inhibition of Ornithine Decarboxylase and Aryl Hydrocarbon Hydroxylase Activities in Rat Epidermis.

Published in:

1982

By:

Raunio, Hannu;
Pelkonen, Olavi

Publication type:

Report

CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity<sup>*</sup>.

Published in:

Clinical Pharmacology & Therapeutics, 2002, v. 71, n. 3, p. 196, doi. 10.1067/mcp.2002.121371

By:

García-Martín, Elena;
Martínez, Carmen;
Pizarro, Rosa M.;
García-Gamito, Francisco J.;
Gullsten, Harriet;
Raunio, Hannu;
Agúndez, José A. G.

Publication type:

Article

CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: Evidence for an allelic variant with altered catalytic activity.

Published in:

Clinical Pharmacology & Therapeutics, 2000, v. 67, n. 1, p. 48, doi. 10.1067/mcp.2000.104391

By:

Sata, Fumihiro;
Sapone, Andrea;
Elizondo, Guillermo;
Stocker, Penny;
Miller, Vaughn P.;
Zheng, Wei;
Raunio, Hannu;
Crespi, Charles L.;
Gonzalez, Frank J.

Publication type:

Article

A Comprehensive Evaluation of Sdox, a Promising H<sub>2</sub>S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.831791

By:

Alov, Petko;
Al Sharif, Merilin;
Aluani, Denitsa;
Chegaev, Konstantin;
Dinic, Jelena;
Divac Rankov, Aleksandra;
Fernandes, Miguel X.;
Fusi, Fabio;
García-Sosa, Alfonso T.;
Juvonen, Risto;
Kondeva-Burdina, Magdalena;
Padrón, José M.;
Pajeva, Ilza;
Pencheva, Tania;
Puerta, Adrián;
Raunio, Hannu;
Riganti, Chiara;
Tsakovska, Ivanka;
Tzankova, Virginia;
Yordanov, Yordan

Publication type:

Article

Polymorphisms of CYP2A6 and its practical consequences.

Published in:

British Journal of Clinical Pharmacology, 2001, v. 52, n. 4, p. 357, doi. 10.1046/j.0306-5251.2001.01500.x

By:

Raunio, Hannu;
Rautio, Arja;
Gullstén, Harriet;
Pelkonen, Olavi

Publication type:

Article

Novel Cyclic Phosphate Prodrug Approach for Cytochrome P450-activated Drugs Containing an Alcohol Functionality.

Published in:

Pharmaceutical Research, 2007, v. 24, n. 4, p. 679, doi. 10.1007/s11095-006-9187-y

By:

Kristiina Huttunen;
Niina Mähönen;
Jukka Leppänen;
Jouko Vepsäläinen;
Risto Juvonen;
Hannu Raunio;
Hanna Kumpulainen;
Tomi Järvinen;
Jarkko Rautio

Publication type:

Article

Cytochrome P450-Mediated Pulmonary Metabolism of Carcinogens.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2011, v. 44, n. 5, p. 583, doi. 10.1165/rcmb.2010-0189RT

By:

Anttila, Sisko;
Raunio, Hannu;
Hakkola, Jukka

Publication type:

Article

Induction and Regulation of Xenobiotic-Metabolizing Cytochrome P450s in the Human A549 Lung Adenocarcinoma Cell Line.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2000, v. 22, n. 3, p. 360, doi. 10.1165/ajrcmb.22.3.3845

By:

Hukkanen, Janne;
Lassila, Arja;
Päivärinta, Katja;
Valanne, Susanna;
Sarpo, Sari;
Hakkola, Jukka;
Pelkonen, Olavi;
Raunio, Hannu

Publication type:

Article

A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probe drugs and their corresponding metabolites in human serum and urine.

Published in:

Analytical & Bioanalytical Chemistry, 2017, v. 409, n. 1, p. 251, doi. 10.1007/s00216-016-9994-x

By:

Puris, Elena;
Pasanen, Markku;
Gynther, Mikko;
Häkkinen, Merja;
Pihlajamäki, Jussi;
Keränen, Tapani;
Honkakoski, Paavo;
Raunio, Hannu;
Petsalo, Aleksanteri

Publication type:

Article

Ultrafast protein structure-based virtual screening with Panther.

Published in:

Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 10, p. 989, doi. 10.1007/s10822-015-9870-3

By:

Niinivehmas, Sanna;
Salokas, Kari;
Lätti, Sakari;
Raunio, Hannu;
Pentikäinen, Olli

Publication type:

Article

Inhibitory effects and oxidation of 6-methylcoumarin, 7-methylcoumarin and 7-formylcoumarin via human CYP2A6 and its mouse and pig orthologous enzymes.

Published in:

Xenobiotica, 2016, v. 46, n. 1, p. 14, doi. 10.3109/00498254.2015.1048327

By:

Juvonen, Risto O.;
Kuusisto, Mira;
Fohrgrup, Carolin;
Pitkänen, Mari H.;
Nevalainen, Tapio J.;
Auriola, Seppo;
Raunio, Hannu;
Pasanen, Markku;
Pentikäinen, Olli T.

Publication type:

Article

Coumarin-Based Profluorescent and Fluorescent Substrates for Determining Xenobiotic-Metabolizing Enzyme Activities In Vitro.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 13, p. 4708, doi. 10.3390/ijms21134708

By:

Raunio, Hannu;
Pentikäinen, Olli;
Juvonen, Risto O.

Publication type:

Article

Detection of mRNA encoding xenobiotic-metabolizing cytochrome P450s in human bronchoalveolar macrophages and peripheral blood lymphocytes.

Published in:

Molecular Carcinogenesis, 1997, v. 20, n. 2, p. 224, doi. 10.1002/(SICI)1098-2744(199710)20:2<224::AID-MC9>3.0.CO;2-M

By:

Hukkanen, Janne;
Hakkola, Jukka;
Anttila, Sisko;
Piipari, Ritva;
Karjalainen, Antti;
Pelkonen, Olavi;
Raunio, Hannu

Publication type:

Article

Inhibition and induction of human cytochrome P450 enzymes: current status.

Published in:

Archives of Toxicology, 2008, v. 82, n. 10, p. 667, doi. 10.1007/s00204-008-0332-8

By:

Pelkonen, Olavi;
Turpeinen, Miia;
Hakkola, Jukka;
Honkakoski, Paavo;
Hukkanen, Janne;
Raunio, Hannu

Publication type:

Article

Expression and Regulation of Xenobiotic- Metabolizing Cytochrome P450 (CYP)Enzymes in Human Lung.

Published in:

Critical Reviews in Toxicology, 2002, v. 32, n. 5, p. 391, doi. 10.1080/20024091064273

By:

Hukkanen, Janne;
Pelkonen, Olavi;
Hakkola, Jukka;
Raunio, Hannu

Publication type:

Article

Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicity

Published in:

Critical Reviews in Toxicology, 1998, v. 28, n. 1, p. 35

By:

Pelkonen, Olavi;
Raunio, Hannu;
Pasanen, Markku;
Hakkola, Jukka

Publication type:

Article

Prediction of Drug Metabolism and Interactions on the Basis ofin vitroInvestigations.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2005, v. 96, n. 3, p. 167, doi. 10.1111/j.1742-7843.2005.pto960305.x

By:

Pelkonen, Olavi;
Turpeinen, Miia;
Uusitalo, Jouko;
Rautio, Arja;
Raunio, Hannu

Publication type:

Article

In vivo-in vitro-in silico pharmacokinetic modelling in drug development: current status and future directions.

Published in:

2011

By:

Pelkonen O;
Turpeinen M;
Raunio H;
Pelkonen, Olavi;
Turpeinen, Miia;
Raunio, Hannu

Publication type:

journal article

In Vivo-In Vitro-In Silico Pharmacokinetic Modelling in Drug Development.

Published in:

Clinical Pharmacokinetics, 2011, v. 50, n. 8, p. 483, doi. 10.2165/11592400-000000000-00000

By:

Pelkonen, Olavi;
Turpeinen, Miia;
Raunio, Hannu

Publication type:

Article

Expression of CYP1A1, CYP1B1 and CYP3A, and polycyclic aromatic hydrocarbon-DNA adduct formation in bronchoalveolar macrophages of smokers and non-smokers.

Published in:

International Journal of Cancer, 2000, v. 86, n. 5, p. 610, doi. 10.1002/(SICI)1097-0215(20000601)86:5<610::AID-IJC2>3.0.CO;2-M

By:

Piipari, Ritva;
Savela, Kirsti;
Nurminen, Tuula;
Hukkanen, Janne;
Raunio, Hannu;
Hakkola, Jukka;
Mäntylä, Timo;
Beaune, Philippe;
Edwards, Robert J.;
Boobis, Alan R.;
Anttila, Sisko

Publication type:

Article