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Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40222-z
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- Article
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37652-0
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- Article
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli.
- Published in:
- PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194126
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- Article
The rheumatoid synovial environment alters fatty acid metabolism in human monocytes and enhances CCL20 secretion.
- Published in:
- Rheumatology, 2020, v. 59, n. 4, p. 869, doi. 10.1093/rheumatology/kez378
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- Article
ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy.
- Published in:
- Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abd5016
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- Article
Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells.
- Published in:
- EMBO Reports, 2023, v. 24, n. 10, p. 1, doi. 10.15252/embr.202256279
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- Article
Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46114-0
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- Article
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia.
- Published in:
- Science Translational Medicine, 2024, v. 16, n. 751, p. 1, doi. 10.1126/scitranslmed.adi5336
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- Publication type:
- Article
Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei.
- Published in:
- PLoS Neglected Tropical Diseases, 2018, v. 12, n. 5, p. 1, doi. 10.1371/journal.pntd.0006450
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- Article