Works by Rasmussen, Michael Højby

Results: 44

Once-weekly Somapacitan is Effective and Well Tolerated in Adults with GH Deficiency: A Randomized Phase 3 Trial.

Published in:

2020

By:

Johannsson, Gudmundur;
Gordon, Murray B;
Rasmussen, Michael Højby;
Holme Håkonsson, Ida;
Karges, Wolfram;
Sværke, Claus;
Tahara, Shigeyuki;
Takano, Koji;
Biller, Beverly M K;
Højby Rasmussen, Michael;
Håkonsson, Ida Holme

Publication type:

journal article

Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial.

Published in:

2020

By:

Sävendahl, Lars;
Battelino, Tadej;
Brod, Meryl;
Rasmussen, Michael Højby;
Horikawa, Reiko;
Juul, Rasmus Vestergaard;
Saenger, Paul;
Højby Rasmussen, Michael;
REAL 3 study group

Publication type:

journal article

Efficacy in Japanese adults with growth hormone deficiency receiving weekly somapacitan or daily growth hormone: results from phase 3 REAL 1 trial.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1534891

By:

Otsuka, Fumio;
Rasmussen, Michael Højby;
Endo, Takaaki;
Sværke, Claus;
Tahara, Shigeyuki;
Johannsson, Gudmundur

Publication type:

Article

Normal Sweat Secretion Despite Impaired Growth Hormone-Insulin-Like Growth Factor-I Axis in Obese Subjects.

Published in:

International Journal of Endocrinology, 2011, p. 1, doi. 10.1155/2011/493840

By:

Rasmussen, Michael Højby;
Juul, Anders;
Main, Katharina M.;
Hilsted, Jannik

Publication type:

Article

Similar safety and efficacy in previously treated adults with growth hormone deficiency randomized to once‐weekly somapacitan or daily growth hormone.

Published in:

Clinical Endocrinology, 2020, v. 93, n. 5, p. 620, doi. 10.1111/cen.14273

By:

Otsuka, Fumio;
Takahashi, Yutaka;
Tahara, Shigeyuki;
Ogawa, Yoshihisa;
Højby Rasmussen, Michael;
Takano, Koji

Publication type:

Article

Somapacitan, a once-weekly reversible albumin-binding GH derivative, in children with GH deficiency: A randomized dose-escalation trial.

Published in:

Clinical Endocrinology, 2017, v. 87, n. 4, p. 350, doi. 10.1111/cen.13409

By:

Battelino, Tadej;
Rasmussen, Michael Højby;
De Schepper, Jean;
Zuckerman‐Levin, Nehama;
Gucev, Zoran;
Sävendahl, Lars;
Fröhlich‐Reiterer, E;
Schmitt, K;
Furthner, D;
Beauloye, V;
Zumsteg, U;
Schwitzgebel, V;
Ibañez, L;
Yeste, D;
López, I;
Barreiro, J;
Tauber, M;
Polak, M;
Hershkovitz, E;
Hamiel, O

Publication type:

Article

Cover Image, Volume 87, Issue 4.

Published in:

Clinical Endocrinology, 2017, v. 87, n. 4, p. i, doi. 10.1111/cen.13471

By:

Battelino, Tadej;
Rasmussen, Michael Højby;
De Schepper, Jean;
Zuckerman‐Levin, Nehama;
Gucev, Zoran;
Sävendahl, Lars

Publication type:

Article

Multiple doses of pegylated long-acting growth hormone are well tolerated in healthy male volunteers and possess a potential once-weekly treatment profile M.H. Rasmussen et al. Tolerability, PK and IGF-I response of a long-acting GH.

Published in:

Clinical Endocrinology, 2010, v. 73, n. 6, p. 769, doi. 10.1111/j.1365-2265.2010.03863.x

By:

Rasmussen, Michael Højby;
Jensen, Lene;
Anderson, Thomas W.;
Klitgaard, Thomas;
Madsen, Jesper

Publication type:

Article

GH administration and discontinuation in healthy elderly men: effects on body composition, GH-related serum markers, resting heart rate and resting oxygen uptake.

Published in:

Clinical Endocrinology, 2001, v. 55, n. 1, p. 77, doi. 10.1046/j.1365-2265.2001.01344.x

By:

Lange, Kai Henrik Wiborg;
Isaksson, Fredrik;
Rasmussen, Michael Højby;
Juul, Anders;
Bülow, Jens;
Kjær, Michael

Publication type:

Article

Efficacy, safety, and insulin-like growth factor I of weekly somapacitan in children with growth hormone deficiency: 3-year results from REAL4 Open Access.

Published in:

European Journal of Endocrinology, 2025, v. 192, n. 5, p. 651, doi. 10.1093/ejendo/lvaf096

By:

Miller, Bradley S;
Blair, Joanne C;
Rasmussen, Michael Højby;
Frystyk, Jan;
Lemminger, Anders Krogh;
Maniatis, Aristides;
Mori, Jun;
Böttcher, Volker;
Kim, Ho-Seong;
Polak, Michel;
Horikawa, Reiko

Publication type:

Article

No effect of growth hormone administration on substrate oxidation during exercise in young, lean men.

Published in:

Journal of Physiology, 2005, v. 567, n. 3, p. 1035, doi. 10.1113/jphysiol.2005.089524

By:

Hansen, Mette;
Morthorst, Rikke;
Larsson, Benny;
Dall, Rolf;
Flyvbjerg, Allan;
Rasmussen, Michael Højby;
Ørskov, Hans;
Kjær, Michael;
Lange, Kai Henrik Wiborg

Publication type:

Article

Acute Growth Hormone Administration Causes Exaggerated Increases in Plasma Lactate and Glycerol during Moderate to High Intensity Bicycling in Trained Young Men.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 11, p. 4966, doi. 10.1210/jc.2001-011797

By:

WIBORG LANGE, KAI HENRIK;
LARSSON, BENNY;
FLYVBJERG, ALLAN;
DALL, ROLF;
BENNEKOU, MORTEN;
RASMUSSEN, MICHAEL HØJBY;
ØRSKOV, HANS;
KJÆR, MICHAEL

Publication type:

Article

Dose Dependency of the Pharmacokinetics and Acute Lipolytic Actions of Growth Hormone.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 10, p. 4691, doi. 10.1210/jc.2002-020563

By:

HANSEN, TROELS KRARUP;
GRAVHOLT, CLAUS HØJBJERG;
ØRSKOV, HANS;
RASMUSSEN, MICHAEL HØJBY;
CHRISTIANSEN, JENS SANDAHL;
JØRGENSEN, JENS OTTO L.

Publication type:

Article

GH Administration Changes Myosin Heavy Chain Isoforms in Skeletal Muscle But Does Not Augment Muscle Strength or Hypertrophy, Either Alone or Combined with Resistance Exercise Training in Healthy Elderly Men.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 2, p. 513, doi. 10.1210/jcem.87.2.8206

By:

WIBORG LANGE, KAI HENRIK;
ANDERSEN, JESPER LØVIND;
BEYER, NINA;
ISAKSSON, FREDRIK;
LARSSON, BENNY;
RASMUSSEN, MICHAEL HØJBY;
JUUL, ANDERS;
BÜLOW, JENS;
KJÆR, MICHAEL

Publication type:

Article

The Acid-Labile Subunit of Human Ternary Insulin-Like Growth Factor Binding Protein Complex in Serum: Hepatosplanchnic Release, Diurnal Variation, Circulating Concentrations in Healthy Subjects...

Published in:

Journal of Clinical Endocrinology & Metabolism, 1998, v. 83, n. 12, p. 4408, doi. 10.1210/jcem.83.12.5311

By:

JUUL, ANDERS;
MØLLER, SØREN;
MOSFELDT-LAURSEN, EVA;
RASMUSSEN, MICHAEL HØJBY;
SCHEIKE, THOMAS;
PEDERSEN, SØREN A.;
KASTRUP, KNUD W.;
YU, HERBERT;
MISTRY, JEHANGIR;
RASMUSSEN, SUSANNE;
MÜLLER, JØRN;
HENRIKSEN, JENS;
SKAKKEBÆK, NIELS E.

Publication type:

Article

Serum Growth Hormone-Binding Protein in Obesity: Effect of a Short-Term, Very Low Calorie Diet and Diet-Induced Weight Loss.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1996, v. 81, n. 4, p. 1519, doi. 10.1210/jc.81.4.1519

By:

RASMUSSEN, MICHAEL HØJBY;
HO, KEN K. Y.;
KJEMS, LISE;
HILSTED, JANNIK

Publication type:

Article

Investigating the Bioavailability and Insulin-like Growth Factor-I Release of Two Different Strengths of Somapacitan: A Randomised, Double-Blind Crossover Trial.

Published in:

Clinical Pharmacokinetics, 2024, v. 63, n. 7, p. 1015, doi. 10.1007/s40262-024-01395-y

By:

Dombernowsky, Sarah Louise;
Damholt, Birgitte Bentz;
Højby Rasmussen, Michael;
Sværke, Claus;
Kildemoes, Rasmus Juul

Publication type:

Article

Population Pharmacokinetics and Pharmacodynamics of Once-Daily Growth Hormone Norditropin<sup>®</sup> in Children and Adults.

Published in:

Clinical Pharmacokinetics, 2021, v. 60, n. 9, p. 1217, doi. 10.1007/s40262-021-01011-3

By:

Papathanasiou, Theodoros;
Agersø, Henrik;
Damholt, Birgitte Bentz;
Højby Rasmussen, Michael;
Kildemoes, Rasmus Juul

Publication type:

Article

Effect of Kidney or Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Somapacitan: Two Open-Label, Parallel-Group Trials.

Published in:

Clinical Pharmacokinetics, 2021, v. 60, n. 8, p. 1015, doi. 10.1007/s40262-021-00990-7

By:

Bentz Damholt, Birgitte;
Dombernowsky, Sarah Louise;
Dahl Bendtsen, Mette;
Bisgaard, Charlotte;
Højby Rasmussen, Michael

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Once-Weekly Somapacitan in Children and Adults: Supporting Dosing Rationales with a Model-Based Analysis of Three Phase I Trials.

Published in:

2019

By:

Juul, Rasmus Vestergaard;
Rasmussen, Michael Højby;
Agersø, Henrik;
Overgaard, Rune Viig

Publication type:

journal article

Reversible Albumin-Binding GH Possesses a Potential Once-Weekly Treatment Profile in Adult Growth Hormone Deficiency.

Published in:

2016

By:

Rasmussen, Michael Højby;
Janukonyté, Jurgita;
Klose, Marianne;
Marina, Djordje;
Tanvig, Mette;
Nielsen, Lene F;
Höybye, Charlotte;
Andersen, Marianne;
Feldt-Rasmussen, Ulla;
Christiansen, Jens Sandahl

Publication type:

journal article

A Reversible Albumin-Binding Growth Hormone Derivative is Well Tolerated and Possesses a Potential Once-Weekly Treatment Profile.

Published in:

2014

By:

Rasmussen, Michael Højby;
Olsen, Minna W Brændholt;
Alifrangis, Lene;
Klim, Søren;
Suntum, Mette

Publication type:

Journal Article

Assessing the impact of growth hormone deficiency and treatment in adults: development of a new disease-specific measure.

Published in:

2014

By:

Brod, Meryl;
Højbjerre, Lise;
Adalsteinsson, Johan Erpur;
Rasmussen, Michael Højby

Publication type:

Journal Article

Pegylated long-acting human growth hormone possesses a promising once-weekly treatment profile, and multiple dosing is well tolerated in adult patients with growth hormone deficiency.

Published in:

2011

By:

Søndergaard, Esben;
Klose, Marianne;
Hansen, Mette;
Hansen, Birgit Sehested;
Andersen, Marianne;
Feldt-Rasmussen, Ulla;
Laursen, Torben;
Rasmussen, Michael Højby;
Christiansen, Jens Sandahl

Publication type:

journal article

Pegylated Long-Acting Human Growth Hormone Is Well-Tolerated in Healthy Subjects and Possesses a Potential Once-Weekly Pharmacokinetic and Pharmacodynamic Treatment Profile.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2010, v. 95, n. 7, p. 3411, doi. 10.1210/jc.2009-2813

By:

Rasmussen, Michael Højby;
Bysted, Britta V.;
Anderson, Thomas W.;
Klitgaard, Thomas;
Madsen, Jesper

Publication type:

Article

Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis.

Published in:

Journal of Physiology, 2010, v. 588, n. 2, p. 341, doi. 10.1113/jphysiol.2009.179325

By:

Doessing, Simon;
Heinemeier, Katja M.;
Holm, Lars;
Mackey, Abigail L.;
Schjerling, Peter;
Rennie, Michael;
Smith, Kenneth;
Reitelseder, Søren;
Kappelgaard, Anne-Marie;
Rasmussen, Michael Højby;
Flyvbjerg, Allan;
Kjaer, Michael

Publication type:

Article

Dose-exposure-IGF-I response of once-weekly somapacitan in adults with GH deficiency.

Published in:

European Journal of Endocrinology, 2022, v. 187, n. 1, p. 27, doi. 10.1530/EJE-21-1167

By:

Kildemoes, Rasmus Juul;
Hollensen, Christian;
Biller, Beverly M. K.;
Johannsson, Gudmundur;
Yutaka Takahashi;
Rasmussen, Michael Højby

Publication type:

Article

Safety and convenience of once-weekly somapacitan in adult GH deficiency: a 26-week randomized, controlled trial.

Published in:

European Journal of Endocrinology, 2018, v. 178, n. 5, p. 491, doi. 10.1530/EJE-17-1073

By:

Johannsson, Gudmundur;
Feldt-Rasmussen, Ulla;
Håkonsson, Ida Holme;
Biering, Henrik;
Rodien, Patrice;
Tahara, Shigeyuki;
Toogood, Andrew;
Rasmussen, Michael Højby

Publication type:

Article

Effects of short-term caloric restriction on circulating free IGF-I, acid-labile subunit, IGF-binding proteins (IGFBPs)-1–4, and IGFBPs-1–3 protease activity in obese subjects.

Published in:

European Journal of Endocrinology, 2006, v. 155, n. 4, p. 575, doi. 10.1530/eje.1.02246

By:

Michael Højby Rasmussen

Publication type:

Article

Understanding burden of illness for child growth hormone deficiency.

Published in:

2017

By:

Brod, Meryl;
Alolga, Suzanne;
Beck, Jane;
Wilkinson, Lars;
Højbjerre, Lise;
Rasmussen, Michael;
Alolga, Suzanne Lessard;
Beck, Jane F;
Rasmussen, Michael Højby

Publication type:

journal article

Weekly somapacitan had no adverse effects on glucose metabolism in adults with growth hormone deficiency.

Published in:

Pituitary, 2023, v. 26, n. 1, p. 57, doi. 10.1007/s11102-022-01283-3

By:

Takahashi, Yutaka;
Biller, Beverly M. K.;
Fukuoka, Hidenori;
Ho, Ken K. Y.;
Rasmussen, Michael Højby;
Nedjatian, Navid;
Sværke, Claus;
Yuen, Kevin C. J.;
Johannsson, Gudmundur

Publication type:

Article

Impact of adult growth hormone deficiency on daily functioning and well-being.

Published in:

BMC Research Notes, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-0500-7-813

By:

Brod, Meryl;
Pohlman, Betsy;
Højbjerre, Lise;
Adalsteinsson, Johan Erpur;
Rasmussen, Michael Højby

Publication type:

Article

Cover Image, Volume 100, Number 4, April 2024.

Published in:

Clinical Endocrinology, 2024, v. 100, n. 4, p. i, doi. 10.1111/cen.15113

By:

Mori, Jun;
Ohata, Yasuhisa;
Fujisawa, Yasuko;
Sato, Yukihito;
Röhrich, Sebastian;
Rasmussen, Michael Højby;
Bang, Rikke Beck;
Horikawa, Reiko

Publication type:

Article

Effective growth hormone replacement with once‐weekly somapacitan in Japanese children with growth hormone deficiency: Results from REAL4, a phase 3 clinical trial.

Published in:

Clinical Endocrinology, 2024, v. 100, n. 4, p. 389, doi. 10.1111/cen.15025

By:

Mori, Jun;
Ohata, Yasuhisa;
Fujisawa, Yasuko;
Sato, Yukihito;
Röhrich, Sebastian;
Rasmussen, Michael Højby;
Bang, Rikke Beck;
Horikawa, Reiko

Publication type:

Article

Efficacy in Japanese adults with growth hormone deficiency receiving weekly somapacitan or daily growth hormone: results from phase 3 REAL 1 trial.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1534891

By:

Otsuka, Fumio;
Rasmussen, Michael Højby;
Endo, Takaaki;
Sværke, Claus;
Tahara, Shigeyuki;
Johannsson, Gudmundur

Publication type:

Article

Effective GH Replacement With Somapacitan in Children With GHD: REAL4 2-year Results and After Switch From Daily GH.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 12, p. 3090, doi. 10.1210/clinem/dgad394

By:

Miller, Bradley S.;
Blair, Joanne C.;
Rasmussen, Michael Højby;
Maniatis, Aristides;
Mori, Jun;
Böttcher, Volker;
Ho-Seong Kim;
Bang, Rikke Beck;
Polak, Michel;
Reiko Horikawa

Publication type:

Article

Weekly Somapacitan in GH Deficiency: 4-Year Efficacy, Safety, and Treatment/Disease Burden Results From REAL 3.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 10, p. 2569, doi. 10.1210/clinem/dgad183

By:

Sävendahl, Lars;
Battelino, Tadej;
Rasmussen, Michael Højby;
Brod, Meryl;
Röhrich, Sebastian;
Saenger, Paul;
Horikawa, Reiko

Publication type:

Article

Response to Letter to the Editor From Chatelain et al: 'Weekly Somapacitan Is Effective and Well Tolerated in Children With GH Deficiency: The Randomized Phase 3 REAL4 Trial'.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 8, p. e647, doi. 10.1210/clinem/dgad095

By:

Miller, Bradley S.;
Blair, Joanne C.;
Rasmussen, Michael Højby;
Maniatis, Aristides;
Kildemoes, Rasmus Juul;
Jun Mori;
Polak, Michel;
Bang, Rikke Beck;
Böttcher, Volker;
Stagi, Stefano;
Reiko Horikawa

Publication type:

Article

Weekly Somapacitan is Effective and Well Tolerated in Children With GH Deficiency: The Randomized Phase 3 REAL4 Trial.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 12, p. 3378, doi. 10.1210/clinem/dgac513

By:

Miller, Bradley S.;
Blair, Joanne C.;
Rasmussen, Michael Højby;
Maniatis, Aristides;
Kildemoes, Rasmus Juul;
Jun Mori;
Polak, Michel;
Bang, Rikke Beck;
Böttcher, Volker;
Stagi, Stefano;
Reiko Horikawa

Publication type:

Article

Effective GH Replacement With Once-weekly Somapacitan vs Daily GH in Children With GHD: 3-year Results From REAL 3.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 5, p. 1357, doi. 10.1210/clinem/dgab928

By:

Sävendahl, Lars;
Battelino, Tadej;
Rasmussen, Michael Højby;
Brod, Meryl;
Saenger, Paul;
Reiko Horikawa

Publication type:

Article

Letter to the Editor From Sävendahl et al.: “Weekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial”.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 2, p. e888, doi. 10.1210/clinem/dgab736

By:

Sävendahl, Lars;
Battelino, Tadej;
Brod, Meryl;
Højby Rasmussen, Michael;
Kildemoes, Rasmus Juul;
Saenger, Paul

Publication type:

Article

Optimal Monitoring of Weekly IGF-I Levels During Growth Hormone Therapy With Once- Weekly Somapacitan.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2021, v. 106, n. 2, p. 567, doi. 10.1210/clinem/dgaa775

By:

Kildemoes, Rasmus Juul;
Rasmussen, Michael Højby;
Agersø, Henrik;
Overgaard, Rune Viig

Publication type:

Article

Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2020, v. 105, n. 4, p. e1847, doi. 10.1210/clinem/dgz310

By:

Sävendahl, Lars;
Battelino, Tadej;
Brod, Meryl;
Rasmussen, Michael Højby;
Horikawa, Reiko;
Juul, Rasmus Vestergaard;
Saenger, Paul

Publication type:

Article

Once-weekly Somapacitan is Effective and Well Tolerated in Adults with GH Deficiency: A Randomized Phase 3 Trial.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2020, v. 105, n. 4, p. e1358, doi. 10.1210/clinem/dgaa049

By:

Johannsson, Gudmundur;
Gordon, Murray B.;
Rasmussen, Michael Højby;
Håkonsson, Ida Holme;
Karges, Wolfram;
Sværke, Claus;
Shigeyuki Tahara;
Koji Takano;
Biller, Beverly M. K.

Publication type:

Article