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Diverse Fab specific for acetylcholine receptor epitopes from a myasthenia gravis thymus combinatorial library.
- Published in:
- International Immunology, 1997, v. 9, n. 9, p. 1311, doi. 10.1093/intimm/9.9.1311
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- Publication type:
- Article
Autoimmune hypothyroidism: T cells caught in the act.
- Published in:
- Nature Medicine, 2004, v. 10, n. 9, p. 895, doi. 10.1038/nm0904-895
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- Publication type:
- Article
Evidence that TSH Receptor A-Subunit Multimers, Not Monomers, Drive Antibody Affinity Maturation in Graves' Disease.
- Published in:
- 2015
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- Publication type:
- journal article
Graves' hyperthyroidism is antibody-mediated but is predominantly a Th1-type cytokine disease.
- Published in:
- 2014
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- Publication type:
- journal article
Thyroid Autoantibodies Display both "Original Antigenic Sin" and epitope Spreading.
- Published in:
- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01845
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- Publication type:
- Article
Breaking Tolerance in Transgenic Mice Expressing the Human TSH Receptor A-Subunit: Thyroiditis, Epitope Spreading and Adjuvant as a 'Double Edged Sword'.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0043517
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- Publication type:
- Article
Novel Information on the Epitope of an Inverse Agonist Monoclonal Antibody Provides Insight into the Structure of the TSH Receptor.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031973
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- Publication type:
- Article
Exceptional Hyperthyroidism and a Role for both Major Histocompatibility Class I and Class II Genes in a Murine Model of Graves' Disease.
- Published in:
- PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021378
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- Publication type:
- Article
Evidence that shed thyrotropin receptor A subunits drive affinity maturation of autoantibodies causing Graves' disease.
- Published in:
- 2009
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- Publication type:
- journal article
Human Monoclonal Thyroglobulin Autoantibodies: Epitopes and Immunoglobulin Genes.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 10, p. 5116, doi. 10.1210/jc.2003-032173
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- Publication type:
- Article
Affinity-Enrichment of Thyrotropin Receptor Autoantibodies from Graves’ Patients and Normal Individuals Provides Insight into Their Properties and Possible Origin from Natural Antibodies.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 9, p. 4734, doi. 10.1210/jc.2003-032068
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- Publication type:
- Article
Thyroid Stimulation Does Not Require Antibodies with Identical Epitopes But Does Involve Recognition of a Critical Conformation at the N Terminus of the Thyrotropin Receptor A-Subunit.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 4, p. 1788, doi. 10.1210/jc.2003-031554
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- Publication type:
- Article
Thyroglobulin-Thyroperoxidase Autoantibodies Are Polyreactive, Not Bispecific: Analysis Using Human Monoclonal Autoantibodies.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 1, p. 371, doi. 10.1210/jc.2002-021073
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- Publication type:
- Article
A Prion-Like Shift between Two Conformational Forms of a Recombinant Thyrotropin Receptor A-Subunit Module: Purification and Stabilization Using Chemical Chaperones of the Form Reactive with Graves’ Autoantibodies.
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- Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 3, p. 1287, doi. 10.1210/jcem.86.3.7363
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- Publication type:
- Article
A Mouse Monoclonal Antibody to a Thyrotropin Receptor Ectodomain Variant Provides Insight into the Exquisite Antigenic Conformational Requirement, Epitopes and in Vivo Concentration of Human Autoantibodies.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 2, p. 702, doi. 10.1210/jcem.84.2.5481
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- Publication type:
- Article
The Human Thyrotropin (TSH) Receptor in a TSH Binding Inhibition Assay for TSH Receptor Autoantibodies*.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 7, p. 2129, doi. 10.1210/jcem.82.7.4092
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- Publication type:
- Article
Recombinant Thyroid Peroxidase-Specific Fab Converted to Immunoglobulin G (IgG) Molecules: Evidence for Thyroid Cell Damage by IgG1, but Not IgG4, Autoantibodies.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 3, p. 925, doi. 10.1210/jcem.82.3.3831
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- Publication type:
- Article
Thyrotropin Receptor Autoantibodies in Serum Are Present at Much Lower Levels Than Thyroid Peroxidase Autoantibodies: Analysis by Flow Cytometry.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 2, p. 500, doi. 10.1210/jcem.82.2.3740
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- Publication type:
- Article
Peri-tumor administration of controlled release anti-CTLA-4 synergizes with systemic anti-PD-1 to induce systemic antitumor immunity while sparing autoimmune toxicity.
- Published in:
- Cancer Immunology, Immunotherapy, 2020, v. 69, n. 9, p. 1737, doi. 10.1007/s00262-020-02579-8
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- Publication type:
- Article
Discoveries in Thyroid Autoimmunity in the Past Century.
- Published in:
- Thyroid, 2023, v. 33, n. 3, p. 278, doi. 10.1089/thy.2022.0275
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- Publication type:
- Article
A Mouse Thyrotropin Receptor A-Subunit Transgene Expressed in Thyroiditis-Prone Mice May Provide Insight into Why Graves' Disease Only Occurs in Humans.
- Published in:
- Thyroid, 2019, v. 29, n. 8, p. 1138, doi. 10.1089/thy.2019.0260
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- Publication type:
- Article
Structure of a Thyrotropin Receptor Monoclonal Antibody Variable Region Provides Insight into Potential Mechanisms for its Inverse Agonist Activity.
- Published in:
- Thyroid, 2018, v. 28, n. 7, p. 933, doi. 10.1089/thy.2018.0176
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- Publication type:
- Article
A Role for Satb1 in Thyroid Autoimmunity?
- Published in:
- 2018
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- Publication type:
- Letter to the Editor
Molecular Cloning and Characterization of c-erb-A mRNA Species in Mouse Neuroblastoma Cells.
- Published in:
- Journal of Neuroendocrinology, 1989, v. 1, n. 5, p. 351, doi. 10.1111/j.1365-2826.1989.tb00128.x
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- Publication type:
- Article
Cathepsin S is not crucial to TSHR processing and presentation in a murine model of Graves' disease.
- Published in:
- Immunology, 2005, v. 116, n. 4, p. 532, doi. 10.1111/j.1365-2567.2005.02255.x
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- Publication type:
- Article
Mechanisms of Autoantibody-Induced Pathology.
- Published in:
- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.00603
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- Publication type:
- Article
A transgenic mouse that spontaneously develops pathogenic TSH receptor antibodies will facilitate study of antigen-specific immunotherapy for human Graves' disease.
- Published in:
- Endocrine (1355008X), 2019, v. 66, n. 2, p. 137, doi. 10.1007/s12020-019-02083-9
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- Publication type:
- Article
Sex, Genetics, and the Control of Thyroxine and Thyrotropin in Mice.
- Published in:
- Thyroid, 2014, v. 24, n. 7, p. 1080, doi. 10.1089/thy.2014.0003
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- Publication type:
- Article
Boris Catz, MD (1923-2013).
- Published in:
- Thyroid, 2013, v. 23, n. 7, p. 777, doi. 10.1089/thy.2013.0316
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- Publication type:
- Article
Genetic Linkages for Thyroxine Released in Response to Thyrotropin Stimulation in Three Sets of Recombinant Inbred Mice Provide Evidence for Shared and Novel Genes Controlling Thyroid Function.
- Published in:
- Thyroid, 2013, v. 23, n. 3, p. 360, doi. 10.1089/thy.2012.0338
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- Publication type:
- Article
Thyrotropin-Blocking Autoantibodies and Thyroid-Stimulating Autoantibodies: Potential Mechanisms Involved in the Pendulum Swinging from Hypothyroidism to Hyperthyroidism or Vice Versa.
- Published in:
- Thyroid, 2013, v. 23, n. 1, p. 14, doi. 10.1089/thy.2012.0374
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- Publication type:
- Article
Role of Self-Tolerance and Chronic Stimulation in the Long-Term Persistence of Adenovirus-Induced Thyrotropin Receptor Antibodies in Wild-Type and Transgenic Mice.
- Published in:
- Thyroid, 2012, v. 22, n. 9, p. 931, doi. 10.1089/thy.2012.0008
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- Publication type:
- Article
Review and Hypothesis: Does Graves' Disease Develop in Non-Human Great Apes?
- Published in:
- Thyroid, 2011, v. 21, n. 12, p. 1359, doi. 10.1089/thy.2011.0209
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- Publication type:
- Article
Subclinical Nonautoimmune Hyperthyroidism in a Family Segregates with a Thyrotropin Receptor Mutation with Weakly Increased Constitutive Activity.
- Published in:
- Thyroid, 2010, v. 20, n. 11, p. 1307, doi. 10.1089/thy.2010.0261
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- Publication type:
- Article
Variable Suppression of Serum Thyroxine in Female Mice of Different Inbred Strains by Triiodothyronine Administered in Drinking Water.
- Published in:
- Thyroid, 2010, v. 20, n. 10, p. 1157, doi. 10.1089/thy.2010.0117
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- Publication type:
- Article
Thyroid Antigens, Not Central Tolerance, Control Responses to Immunization in BALB/c Versus C57BL/6 Mice.
- Published in:
- Thyroid, 2009, v. 19, n. 5, p. 503, doi. 10.1089/thy.2008.0420
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- Publication type:
- Article
Thyroid Peroxidase as an Autoantigen.
- Published in:
- Thyroid, 2007, v. 17, n. 10, p. 939, doi. 10.1089/thy.2007.0169
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- Publication type:
- Article
The Thyrotropin Receptor in Graves' Disease.
- Published in:
- Thyroid, 2007, v. 17, n. 10, p. 911, doi. 10.1089/thy.2007.0170
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- Publication type:
- Article
HLA-DR3 Transgenic Mice Immunized with Adenovirus Encoding the Thyrotropin Receptor: T Cell Epitopes and Functional Analysis of the CD40 Graves' Polymorphism.
- Published in:
- Thyroid, 2006, v. 16, n. 12, p. 1221, doi. 10.1089/thy.2006.16.1221
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- Publication type:
- Article
Blockade of Costimulation Between T Cells and Antigen-Presenting Cells: An Approach to Suppress Murine Graves' Disease Induced Using Thyrotropin Receptor-Expressing Adenovirus.
- Published in:
- Thyroid, 2006, v. 16, n. 5, p. 427
- By:
- Publication type:
- Article
Antibodies Focused on the Human Autoantibody Immunodominant Region Are Induced by B Lymphocytes that Constitutively Express Thyroid Peroxidase Diverted to the Major Histocompatibility Complex II Pathway.
- Published in:
- Thyroid, 2006, v. 16, n. 4, p. 343, doi. 10.1089/thy.2006.16.343
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- Publication type:
- Article
Gene Expression Profiles Differ Markedly in Mouse StrainsThat Are (or Are Not) Susceptible to HyperthyroidismInduced Using Thyrotropin Receptor-Expressing Adenovirus.
- Published in:
- Thyroid, 2005, v. 15, n. 11, p. 1229
- By:
- Publication type:
- Article
Evidence That the Thyrotropin Receptor Protease is Membrane-Associated and is Not Within Lipid Rafts.
- Published in:
- Thyroid, 2004, v. 14, n. 10, p. 801
- By:
- Publication type:
- Article
Why Measure Thyroglobulin Autoantibodies Rather Than Thyroid Peroxidase Autoantibodies?
- Published in:
- Thyroid, 2004, v. 14, n. 7, p. 510
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- Publication type:
- Article
Thyrotropin Receptor-DNA Vaccination of Transgenic Mice Expressing HLA-DR3 or HLA-DQ6b.
- Published in:
- Thyroid, 2003, v. 13, n. 10, p. 911
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- Publication type:
- Article
A Major Role for Non-Major Histocompatibility Complex Genes But not for Microorganisms in a Novel Murine Model of Graves' Hyperthyroidism.
- Published in:
- Thyroid, 2003, v. 13, n. 3, p. 233, doi. 10.1089/105072503321582024
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- Publication type:
- Article
Graves' Disease: The T<sub>H</sub>1/T<sub>H</sub>2 Paradigm versus the "Hygiene" Hypothesis and Defective Immune Regulation.
- Published in:
- Thyroid, 2003, v. 13, n. 2, p. 127, doi. 10.1089/105072503321319413
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- Publication type:
- Article
Evidence that the Complement Control Protein-Epidermal Growth Factor-Like Domain of Thyroid Peroxidase Lies on the Fringe of the Immunodominant Region Recognized by Autoantibodies.
- Published in:
- Thyroid, 2002, v. 12, n. 12, p. 1085, doi. 10.1089/105072502321085180
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- Publication type:
- Article
Peptide Scanning for Thyrotropin Receptor T-Cell Epitopes in Mice Vaccinated with Naked DNA.
- Published in:
- Thyroid, 2002, v. 12, n. 9, p. 755, doi. 10.1089/105072502760339316
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- Publication type:
- Article
Human Monoclonal Autoantibodies to B-Cell Epitopes Outside the Thyroid Peroxidase Autoantibody Immunodominant Region.
- Published in:
- Thyroid, 2001, v. 11, n. 4, p. 301, doi. 10.1089/10507250152039037
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- Publication type:
- Article