Works by Ranum P

Results: 28

Optimized AAV capsids for basal ganglia diseases show robust potency and distribution.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60000-3

By:

Leib, D. E.;
Chen, Y. H.;
Tecedor, L.;
Ranum, P. T.;
Keiser, M. S.;
Lewandowski, B. C.;
Carrell, E. M.;
Arora, S.;
Huerta-Ocampo, I.;
Lai, D.;
Fluta, C. M.;
Cheng, C.;
Liu, X.;
Davidson, B. L.

Publication type:

Article

Staufen Impairs Autophagy in Neurodegeneration.

Published in:

Annals of Neurology, 2023, v. 93, n. 2, p. 398, doi. 10.1002/ana.26515

By:

Paul, Sharan;
Dansithong, Warunee;
Gandelman, Mandi;
Figueroa, Karla P.;
Zu, Tao;
Ranum, Laura P. W.;
Scoles, Daniel R.;
Pulst, Stefan M.

Publication type:

Article

Compound loss of muscleblind-like function in myotonic dystrophy.

Published in:

EMBO Molecular Medicine, 2013, v. 5, n. 12, p. 1887, doi. 10.1002/emmm.201303275

By:

Lee, Kuang‐Yung;
Li, Moyi;
Manchanda, Mini;
Batra, Ranjan;
Charizanis, Konstantinos;
Mohan, Apoorva;
Warren, Sonisha A.;
Chamberlain, Christopher M.;
Finn, Dustin;
Hong, Hannah;
Ashraf, Hassan;
Kasahara, Hideko;
Ranum, Laura P. W.;
Swanson, Maurice S.

Publication type:

Article

SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.

Published in:

EMBO Journal, 2018, v. 37, n. 19, p. 1, doi. 10.15252/embj.201899023

By:

Ayhan, Fatma;
Perez, Barbara A.;
Shorrock, Hannah K.;
Zu, Tao;
Banez‐Coronel, Monica;
Reid, Tammy;
Furuya, Hirokazu;
Clark, H. Brent;
Troncoso, Juan C.;
Ross, Christopher A.;
Subramony, S. H.;
Ashizawa, Tetsuo;
Wang, Eric T.;
Yachnis, Anthony T.;
Ranum, Laura P. W.

Publication type:

Article

The alternative initiation factor eIF2A plays key role in RAN translation of myotonic dystrophy type 2 CCUG•CAGG repeats.

Published in:

Human Molecular Genetics, 2021, v. 30, n. 11, p. 1020, doi. 10.1093/hmg/ddab098

By:

Tusi, Solaleh Khoramian;
Nguyen, Lien;
Thangaraju, Kiruphagaran;
Li, Jian;
Cleary, John D;
Zu, Tao;
Ranum, Laura P W

Publication type:

Article

Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 24, p. 3900, doi. 10.1093/hmg/ddaa279

By:

Pattamatta, Amrutha;
Nguyen, Lien;
Olafson, Hailey R;
Scotti, Marina M;
Laboissonniere, Lauren A;
Richardson, Jared;
Berglund, J Andrew;
Zu, Tao;
Wang, Eric T;
Ranum, Laura P W

Publication type:

Article

Mutant β-III Spectrin Causes mGluR1α Mislocalization and Functional Deficits in a Mouse Model of Spinocerebellar Ataxia Type 5.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 30, p. 9891, doi. 10.1523/JNEUROSCI.0876-14.2014

By:

Armbrust, Karen R.;
Xinming Wang;
Hathorn, Tyisha J.;
Cramer, Samuel W.;
Gang Chen;
Tao Zu;
Takashi Kangas;
Zink, Anastasia N.;
Öz, Gülin;
Ebner, Timothy J.;
Ranum, Laura P. W.

Publication type:

Article

Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8.

Published in:

Nature Genetics, 2006, v. 38, n. 7, p. 758, doi. 10.1038/ng1827

By:

Moseley, Melinda L.;
Tao Zu;
Ikeda, Yoshio;
Wangcai Gao;
Mosemiller, Anne K.;
Daughters, Randy S.;
Gang Chen;
Weatherspoon, Marcy R.;
Clark, H. Brent;
Ebner, Timothy J.;
Day, John W.;
Ranum, Laura P. W.

Publication type:

Article

Spectrin mutations cause spinocerebellar ataxia type 5.

Published in:

Nature Genetics, 2006, v. 38, n. 2, p. 184, doi. 10.1038/ng1728

By:

Ikeda, Yoshio;
Dick, Katherine A.;
Weatherspoon, Marcy R.;
Gincel, Dan;
Armbrust, Karen R.;
Dalton, Joline C.;
Stevanin, Giovanni;
Dürr, Alexandra;
Zühlke, Christine;
Bürk, Katrin;
Clark, H. Brent;
Brice, Alexis;
Rothstein, Jeffrey D.;
Schut, Lawrence J.;
Day, John W.;
Ranum, Laura P. W.

Publication type:

Article

Genetic mapping of a second myotonic dystrophy locus.

Published in:

Nature Genetics, 1998, v. 19, n. 2, p. 196, doi. 10.1038/570

By:

Ranum, Laura P. W.;
Rasmussen, Paul F.;
Benzow, Kellie A.;
Koob, Michael D.;
Day, John W.

Publication type:

Article

Machado-Joseph disease in a Sudanese family links East Africa to Portuguese families and allows reestimation of ancestral age of the Machado lineage.

Published in:

Human Genetics, 2023, v. 142, n. 12, p. 1747, doi. 10.1007/s00439-023-02611-8

By:

Martins, Sandra;
Yahia, Ashraf;
Costa, Inês P. D.;
Siddig, Hassab E.;
Abubaker, Rayan;
Koko, Mahmoud;
Corral-Juan, Marc;
Matilla-Dueñas, Antoni;
Brice, Alexis;
Durr, Alexandra;
Leguern, Eric;
Ranum, Laura P. W.;
Amorim, António;
Elsayed, Liena E. O.;
Stevanin, Giovanni;
Sequeiros, Jorge

Publication type:

Article

A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0173565

By:

Khare, Swati;
Nick, Jerelyn A.;
Zhang, Yalan;
Galeano, Kira;
Butler, Brittany;
Khoshbouei, Habibeh;
Rayaprolu, Sruti;
Hathorn, Tyisha;
Ranum, Laura P. W.;
Smithson, Lisa;
Golde, Todd E.;
Paucar, Martin;
Morse, Richard;
Raff, Michael;
Simon, Julie;
Nordenskjöld, Magnus;
Wirdefeldt, Karin;
Rincon-Limas, Diego E.;
Lewis, Jada;
Kaczmarek, Leonard K.

Publication type:

Article

Vitamin A fortification of wheat flour: considerations and current recommendations.

Published in:

2010

By:

Klemm RD;
West KP Jr;
Palmer AC;
Johnson Q;
Randall P;
Ranum P;
Northrop-Clewes C;
Klemm, Rolf D W;
West, Keith P Jr;
Palmer, Amanda C;
Johnson, Quentin;
Randall, Philip;
Ranum, Peter;
Northrop-Clewes, Christine

Publication type:

journal article

Zinc fortification of cereal flours: current recommendations and research needs.

Published in:

2010

By:

Brown KH;
Hambidge KM;
Ranum P;
Zinc Fortification Working Group;
Brown, Kenneth H;
Hambidge, K Michael;
Ranum, Peter

Publication type:

journal article

Revised recommendations for iron fortification of wheat flour and an evaluation of the expected impact of current national wheat flour fortification programs.

Published in:

2010

By:

Hurrell R;
Ranum P;
de Pee S;
Biebinger R;
Hulthen L;
Johnson Q;
Lynch S;
Hurrell, Richard;
Ranum, Peter;
de Pee, Saskia;
Biebinger, Ralf;
Hulthen, Lena;
Johnson, Quentin;
Lynch, Sean

Publication type:

journal article

Molecular genetics of spinocerebellar ataxia type 8 (SCA8).

Published in:

Cytogenetic & Genome Research, 2003, v. 100, n. 1-4, p. 175, doi. 10.1159/000072852

By:

Mosemiller, A. K.;
Dalton, J. C.;
Day, J. W.;
Ranum, Laura P. W.

Publication type:

Article

Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila.

Published in:

Journal of Cell Biology, 2010, v. 189, n. 1, p. 143, doi. 10.1083/jcb.200905158

By:

Lorenzo, Damaris N.;
Li, Min-gang;
Mische, Sarah E.;
Armbrust, Karen R.;
Ranum, Laura P. W.;
Hays, Thomas S.

Publication type:

Article

Dutch myotonic dystrophy type 2 patients and a North-African DM2 family carry the common European founder haplotype.

Published in:

European Journal of Human Genetics, 2011, v. 19, n. 5, p. 567, doi. 10.1038/ejhg.2010.233

By:

Coenen, Marieke J. H.;
Tieleman, Alide A.;
Schijvenaars, Mascha M. V. A. P.;
Leferink, Maike;
Ranum, Laura P. W.;
Scheffer, Hans;
van Engelen, Baziel G. M.

Publication type:

Article

Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 21, p. 4645, doi. 10.1093/hmg/dds306

By:

Chamberlain, Christopher M.;
Ranum, Laura P. W.

Publication type:

Article

Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15962-x

By:

Sznajder, Łukasz J.;
Scotti, Marina M.;
Shin, Jihae;
Taylor, Katarzyna;
Ivankovic, Franjo;
Nutter, Curtis A.;
Aslam, Faaiq N.;
Subramony, S. H.;
Ranum, Laura P. W.;
Swanson, Maurice S.

Publication type:

Article

Frequency of KCNC3 DNA Variants as Causes of Spinocerebellar Ataxia 13 (SCA13).

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017811

By:

Figueroa, Karla P.;
Waters, Michael F.;
Garibyan, Vartan;
Bird, Thomas D.;
Gomez, Christopher M.;
Ranum, Laura P. W.;
Minassian, Natali A.;
Papazian, Diane M.;
Pulst, Stefan M.

Publication type:

Article

SNP Haplotype Mapping in a Small ALS Family.

Published in:

PLoS ONE, 2009, v. 4, n. 5, p. 1, doi. 10.1371/journal.pone.0005687

By:

Krueger, Katherine A. Dick;
Tsuji, Shoji;
Fukuda, Yoko;
Takahashi, Yuji;
Goto, Jun;
Mitsui, Jun;
Ishiura, Hiroyuki;
Dalton, Joline C.;
Miller, Michael B.;
Day, John W.;
Ranum, Laura P. W.

Publication type:

Article

Nuclear localization of the spinocerebellar ataxia type 7 protein, ataxin-7.

Published in:

Human Molecular Genetics, 1999, v. 8, n. 9, p. 1657, doi. 10.1093/hmg/8.9.1657

By:

Kaytor, Michael D.;
Duvick, Lisa A.;
Skinner, Pamela J.;
Koob, Michael D.;
Ranum, Laura P. W.;
Orr, Harry T.

Publication type:

Article

Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1.

Published in:

Brain: A Journal of Neurology, 2023, v. 146, n. 10, p. 4217, doi. 10.1093/brain/awad148

By:

Nutter, Curtis A;
Kidd, Benjamin M;
Carter, Helmut A;
Hamel, Johanna I;
Mackie, Philip M;
Kumbkarni, Nayha;
Davenport, Mackenzie L;
Tuyn, Dana M;
Gopinath, Adithya;
Creigh, Peter D;
Sznajder, Łukasz J;
Wang, Eric T;
Ranum, Laura P W;
Khoshbouei, Habibeh;
Day, John W;
Sampson, Jacinda B;
Prokop, Stefan;
Swanson, Maurice S

Publication type:

Article

Extragenic Suppression and Synthetic Lethality Among Chlamydomonas reinhardtii Mutants Resistant to Anti-Microtubule Drugs.

Published in:

Genetics, 1989, v. 122, n. 3, p. 567

By:

James, Steven W.;
Silflow, Carolyn D.;
Thompson, Michael D.;
Ranum, Laura P. W.;
Lefebvre, Paul A.

Publication type:

Article

Mapping Flagellar Genes in Chlamydomonas Using Restriction Fragment Length Polymorphisms.

Published in:

Genetics, 1988, v. 120, n. 1, p. 109

By:

Ranum, Laura P. W.;
Thompson, Michael D.;
Schloss, Jeffery A.;
Lefebvre, Paul A.;
Silflow, Carolyn D.

Publication type:

Article

Mutants Resistant to Anti-Microtubule Herbicides Map to a Locus on the uni Linkage Group in Chlamydomonas reinhardtii.

Published in:

Genetics, 1988, v. 118, n. 1, p. 141

By:

James, Steven W.;
Ranum, Laura P. W.;
Silflow, Carolyn D.;
Lefebvre, Paul A.

Publication type:

Article

RNA Gain-of-Function in Spinocerebellar Ataxia Type 8.

Published in:

PLoS Genetics, 2009, v. 5, n. 8, p. 1, doi. 10.1371/journal.pgen.1000600

By:

Daughters, Randy S.;
Tuttle, Daniel L.;
Wangcai Gao;
Ikeda, Yoshio;
Moseley, Melinda L.;
Ebner, Timothy J.;
Swanson, Maurice S.;
Ranum, Laura P. W.

Publication type:

Article