Works matching AU Ransohoff, Richard M

Results: 141

Expression of fractalkine receptor CX3CR1 on cochlear macrophages influences survival of hair cells following ototoxic injury.

Published in:

2010

By:

EISUKE SATO;
SHICK, H. ELIZABETH;
RANSOHOFF, RICHARD M.;
KEIKO HIROSE;
Sato, Eisuke;
Hirose, Keiko

Publication type:

journal article

CC chemokine receptor 2 is protective against noise-induced hair cell death: studies in CX3CR1(+/GFP) mice.

Published in:

2006

By:

Sautter, Nathan;
Shick, Elizabeth;
Ransohoff, Richard;
Charo, Israel;
Hirose, Keiko;
Sautter, Nathan B;
Shick, Elizabeth H;
Ransohoff, Richard M;
Charo, Israel F

Publication type:

journal article

Turning over the Chance card on MS susceptibility.

Published in:

Nature Immunology, 2010, v. 11, n. 7, p. 570, doi. 10.1038/ni0710-570

By:

Ransohoff, Richard M.

Publication type:

Article

Pharmacological depletion of microglia alleviates neuronal and vascular damage in the diabetic CX3CR1-WT retina but not in CX3CR1-KO or hCX3CR1I249/ M280-expressing retina.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1130735

By:

Church, Kaira A.;
Rodriguez, Derek;
Mendiola, Andrew S.;
Vanegas, Difernando;
Gutierrez, Irene L.;
Tamayo, Ian;
Amadu, Abdul;
Velazquez, Priscila;
Cardona, Sandra M.;
Gyoneva, Stefka;
Cotleur, Anne C.;
Ransohoff, Richard M.;
Kaur, Tejbeer;
Cardona, Astrid E.

Publication type:

Article

CXCL12-Induced Monocyte-Endothelial Interactions Promote Lymphocyte Transmigration Across an in Vitro Blood-Brain Barrier.

Published in:

Science Translational Medicine, 2012, v. 4, n. 119, p. 1, doi. 10.1126/scitranslmed.3003197

By:

Shumei Man;
Tucky, Barbara;
Cotleur, Anne;
Drazba, Judith;
Takeshita, Yukio;
Ransohoff, Richard M.

Publication type:

Article

Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 3, p. 637, doi. 10.1523/JNEUROSCI.2110-16.2017

By:

Jay, Taylor R.;
Hirsch, Anna M.;
Broihier, Margaret L.;
Miller, Crystal M.;
Neilson, Lee E.;
Ransohoff, Richard M.;
Lamb, Bruce T.;
Landreth, Gary E.

Publication type:

Article

Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease.

Published in:

Journal of Neuroscience, 2015, p. 6532, doi. 10.1523/JNEUROSCI.4586-14.2015

By:

Savage, Julie C.;
Jay, Taylor;
Goduni, Elanda;
Quigley, Caitlin;
Mariani, Monica M.;
Malm, Tarja;
Ransohoff, Richard M.;
Lamb, Bruce T.;
Landreth, Gary E.

Publication type:

Article

Opposing Effects of Membrane-Anchored CX3CL1 on Amyloid and Tau Pathologies via the p38 MAPK Pathway.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 37, p. 12538, doi. 10.1523/JNEUROSCI.0853-14.2014

By:

Lee, Sungho;
Xu, Guixiang;
Jay, Taylor R.;
Bhatta, Sabina;
Kim, Ki-Wook;
Jung, Steffen;
Landreth, Gary E.;
Ransohoff, Richard M.;
Lamb, Bruce T.

Publication type:

Article

Immunology: Barrier to electrical storms.

Published in:

Nature, 2009, v. 457, n. 7226, p. 155, doi. 10.1038/457155a

By:

Ransohoff, Richard M.

Publication type:

Article

Inflammatory disease: Assault on the guardian.

Published in:

Nature, 2007, v. 448, n. 7152, p. 421, doi. 10.1038/448421a

By:

Ransohoff, Richard M.

Publication type:

Article

Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion.

Published in:

Stem Cells, 2016, v. 34, n. 8, p. 2026, doi. 10.1002/stem.2393

By:

Otvos, Balint;
Silver, Daniel J.;
Mulkearns-Hubert, Erin E.;
Alvarado, Alvaro G.;
Turaga, Soumya M.;
Sorensen, Mia D.;
Rayman, Patricia;
Flavahan, William A;
Hale, James S.;
Stoltz, Kevin;
Sinyuk, Maksim;
Wu, Qiulian;
Jarrar, Awad;
Kim, Sung-Hak;
Fox, Paul L.;
Nakano, Ichiro;
Rich, Jeremy N.;
Ransohoff, Richard M.;
Finke, James;
Kristensen, Bjarne W.

Publication type:

Article

Inflammatory Cell Migration into the Central Nervous System: A Few New Twists on an Old Tale.

Published in:

Brain Pathology, 2007, v. 17, n. 2, p. 243, doi. 10.1111/j.1750-3639.2007.00067.x

By:

Man, Shumei;
Ubogu, Eroboghene E.;
Ransohoff, Richard M.

Publication type:

Article

Interlinking-6 Protects Anterior Horn Neurons from Lethal Virus-Induced Injury.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 2, p. 481, doi. 10.1523/JNEUROSCI.23-02-00481.2003

By:

Pavelko, Kevin D.;
Howe, Charles L.;
Drescher, Kristin M.;
Gamez, Jeff D.;
Johnson, Aaron J.;
Tao Wei;
Ransohoff, Richard M.;
Rodriguez, Moses

Publication type:

Article

Innate immunity in the central nervous system.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 4, p. 1164, doi. 10.1172/JCI58644

By:

Ransohoff, Richard M.;
Brown, Melissa A.

Publication type:

Article

A mighty mouse: building a better model of multiple sclerosis.

Published in:

2006

By:

Ransohoff, Richard M.

Publication type:

Editorial

Monocyte-secreted Wnt reduces the efficiency of central nervous system remyelination.

Published in:

PLoS Biology, 2025, v. 23, n. 4, p. 1, doi. 10.1371/journal.pbio.3003073

By:

Hill, Bianca M.;
Holloway, Rebecca K.;
Forbes, Lindsey H.;
Davies, Claire L.;
Monteiro, Jonathan K.;
Brown, Christina M.;
Rose, Jamie;
Fudge, Neva;
Plant, Pamela J.;
Mahmood, Ayisha;
Brand-Arzamendi, Koroboshka;
Kent, Sarah A.;
Molina-Gonzalez, Irene;
Gyoneva, Stefka;
Ransohoff, Richard M.;
Wipke, Brian;
Priller, Josef;
Schneider, Raphael;
Moore, Craig S.;
Miron, Veronique E.

Publication type:

Article

The anatomical and cellular basis of immune surveillance in the central nervous system.

Published in:

2012

By:

Ransohoff RM;
Engelhardt B;
Ransohoff, Richard M;
Engelhardt, Britta

Publication type:

journal article

The anatomical and cellular basis of immune surveillance in the central nervous system.

Published in:

Nature Reviews Immunology, 2012, v. 12, n. 9, p. 623, doi. 10.1038/nri3265

By:

Ransohoff, Richard M.;
Engelhardt, Britta

Publication type:

Article

CX3CR1-dependent recruitment of mature NK cells into the central nervous system contributes to control autoimmune neuroinflammation.

Published in:

European Journal of Immunology, 2016, v. 46, n. 8, p. 1984, doi. 10.1002/eji.201546194

By:

Hertwig, Laura;
Hamann, Isabell;
Romero‐Suarez, Silvina;
Millward, Jason M.;
Pietrek, Rebekka;
Chanvillard, Coralie;
Stuis, Hanna;
Pollok, Karolin;
Ransohoff, Richard M.;
Cardona, Astrid E.;
Infante‐Duarte, Carmen

Publication type:

Article

The <italic>T</italic>rem<italic>2</italic> R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0262-8

By:

Cheng-Hathaway, Paul J.;
Reed-Geaghan, Erin G.;
Jay, Taylor R.;
Casali, Brad T.;
Bemiller, Shane M.;
Puntambekar, Shweta S.;
von Saucken, Victoria E.;
Williams, Roxanne Y.;
Karlo, J. Colleen;
Moutinho, Miguel;
Xu, Guixiang;
Ransohoff, Richard M.;
Lamb, Bruce T.;
Landreth, Gary E.

Publication type:

Article

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0216-6

By:

Bemiller, Shane M.;
McCray, Tyler J.;
Allan, Kevin;
Formica, Shane V.;
Guixiang Xu;
Wilson$5, Gina;
Kokiko-Cochran, Olga N.;
Crish, Samuel D.;
Lasagna-Reeves, Cristian A.;
Ransohoff, Richard M.;
Landreth, Gary E.;
Lamb, Bruce T.

Publication type:

Article

Editors' preface: Microglia-A new era dawns.

Published in:

Glia (0894-1491), 2013, v. 61, n. 1, p. 1, doi. 10.1002/glia.22439

By:

Ransohoff, Richard M.;
Prinz, Marco

Publication type:

Article

MMP9 deficiency does not decrease blood-brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis.

Published in:

Glia (0894-1491), 2011, v. 59, n. 11, p. 1770, doi. 10.1002/glia.21222

By:

Savarin, Carine;
Stohlman, Stephen A.;
Rietsch, Anna M.;
Butchi, Niranjan;
Ransohoff, Richard M.;
Bergmann, Cornelia C.

Publication type:

Article

CXCR2 signaling protects oligodendrocyte progenitor cells from IFN-γ/CXCL10-mediated apoptosis.

Published in:

Glia (0894-1491), 2011, v. 59, n. 10, p. 1518, doi. 10.1002/glia.21195

By:

Tirotta, Emanuele;
Ransohoff, Richard M.;
Lane, Thomas E.

Publication type:

Article

Chemokine receptor CXCR4 signaling modulates the growth factor-induced cell cycle of self-renewing and multipotent neural progenitor cells.

Published in:

Glia (0894-1491), 2011, v. 59, n. 1, p. 108, doi. 10.1002/glia.21080

By:

Li, Meizhang;
Chang, Cathleen J.;
Lathia, Justin D.;
Wang, Li;
Pacenta, Holly L.;
Cotleur, Anne;
Ransohoff, Richard M.

Publication type:

Article

Astrocyte differentiation selectively upregulates CCL2/monocyte chemoattractant protein‐1 in cultured human brain‐derived progenitor cellsThis article is a U.S. Government work and, as such, is in the public domain in the United States of America.

Published in:

Glia (0894-1491), 2006, v. 53, n. 1, p. 81, doi. 10.1002/glia.20261

By:

Diane M.P. Lawrence;
Pankaj Seth;
Linda Durham;
Frank Diaz;
Roosevelt Boursiquot;
Richard M. Ransohoff;
Eugene O. Major

Publication type:

Article

TGFβ1 selectively up-regulates CCR1 expression in primary murine astrocytes.

Published in:

Glia (0894-1491), 2000, v. 30, n. 1, p. 1, doi. 10.1002/(SICI)1098-1136(200003)30:1<1::AID-GLIA1>3.0.CO;2-Q

By:

Han, Yulong;
Wang, Jintang;
Zhou, Z.-H. Lucy;
Ransohoff, Richard M.

Publication type:

Article

Three or more routes for leukocyte migration into the central nervous system.

Published in:

Nature Reviews Immunology, 2003, v. 3, n. 7, p. 569, doi. 10.1038/nri1130

By:

Ransohoff, Richard M.;
Kivisakk, Pia;
Kidd, Grahame

Publication type:

Article

Natural killer cells and innate lymphoid cells 1 tune anxiety-like behavior and memory in mice via interferon-γ and acetylcholine.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38899-3

By:

Garofalo, Stefano;
Cocozza, Germana;
Mormino, Alessandro;
Bernardini, Giovanni;
Russo, Eleonora;
Ielpo, Donald;
Andolina, Diego;
Ventura, Rossella;
Martinello, Katiuscia;
Renzi, Massimiliano;
Fucile, Sergio;
Laffranchi, Mattia;
Mortari, Eva Piano;
Carsetti, Rita;
Sciumè, Giuseppe;
Sozzani, Silvano;
Santoni, Angela;
Tremblay, Marie-Eve;
Ransohoff, Richard M.;
Limatola, Cristina

Publication type:

Article

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica.

Published in:

Science Translational Medicine, 2017, p. 1, doi. 10.1126/scitranslmed.aai9111

By:

Fumitaka Shimizu;
Schaller, Kristin L.;
Owens, Gregory P.;
Cotleur, Anne C.;
Kellner, Debra;
Yukio Takeshita;
Obermeier, Birgit;
Kryzer, Thomas J.;
Yasuteru Sano;
Takashi Kanda;
Lennon, Vanda A.;
Ransohoff, Richard M.;
Bennett, Jeffrey L.

Publication type:

Article

Correction: Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice.

Published in:

2017

By:

Saederup, Noah;
Cardona, Astrid E.;
Croft, Kelsey;
Mizutani, Makiko;
Cotleur, Anne C.;
Tsou, Chia-Lin;
Ransohoff, Richard M.;
Charo, Israel F.

Publication type:

Correction Notice

Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment.

Published in:

Brain: A Journal of Neurology, 2006, v. 129, n. 1, p. 200, doi. 10.1093/brain/awh680

By:

Markus Krumbholz;
Diethilde Theil;
Sabine Cepok;
Bernhard Hemmer;
Pia Kiviskk;
Richard M. Ransohoff;
Monika Hofbauer;
Cinthia Farina;
Tobias Derfuss;
Caroline Hartle;
Jia Newcombe;
Reinhard Hohlfeld;
Edgar Meinl

Publication type:

Article

A role for humoral mechanisms in the pathogenesis of Devic’s neuromyelitis optica.

Published in:

Brain: A Journal of Neurology, 2002, v. 125, n. 7, p. 1450, doi. 10.1093/brain/awf151

By:

Lucchinetti, Claudia F.;
Mandler, Raul N.;
McGavern, Dorian;
Bruck, Wolfgang;
Gleich, Gerald;
Ransohoff, Richard M.;
Trebst, Corinna;
Weinshenker, Brian;
Wingerchuk, Dean;
Parisi, Joseph E.;
Lassmann, Hans

Publication type:

Article

Chemokines and chemokine receptors in inflammatory demyelinating neuropathies: a central role for IP‐10.

Published in:

Brain: A Journal of Neurology, 2002, v. 125, n. 4, p. 823, doi. 10.1093/brain/awf070

By:

Kieseier, Bernd C.;
Tani, Marie;
Mahad, Don;
Oka, Nobuyuki;
Ho, Tony;
Woodroofe, Nicola;
Griffin, John W.;
Toyka, Klaus V.;
Ransohoff, Richard M.;
Hartung, Hans‐Peter

Publication type:

Article

IL-17-Induced Act1-Mediated Signaling Is Critical for Cuprizone-Induced Demyelination.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 24, p. 8284, doi. 10.1523/JNEUROSCI.0841-12.2012

By:

Zizhen Kang;
Liping Liu;
Spangler, Roo;
Spear, Charles;
Chenhui Wang;
Gulen, Muhammet Fatih;
Veenstra, Mike;
Wenjun Ouyang;
Ransohoff, Richard M.;
Xiaoxia Li

Publication type:

Article

Deficient CX3CR1 Signaling Promotes Recovery after Mouse Spinal Cord Injury by Limiting the Recruitment and Activation of Ly6Clo/iNOS+ Macrophages.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 27, p. 9910, doi. 10.1523/JNEUROSCI.2114-11.2011

By:

Donnelly, Dustin J.;
Longbrake, Erin E.;
Shawler, Todd M.;
Kiger, Kristina A.;
Wenmin Lai;
Tovar, C. Amy;
Ransohoff, Richard M.;
Popovich, Phillip G.

Publication type:

Article

Myelin Repair Is Accelerated by Inactivating CXCR2 on Nonhematopoietic Cells.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 27, p. 9074, doi. 10.1523/JNEUROSCI.1238-10.2010

By:

LiPing Liu;
Darnall, Lindsey;
Taofang Hu;
Choi, Karen;
Lane, Thomas E.;
Ransohoff, Richard M.

Publication type:

Article

Defining interferon β response status in multiple sclerosis patients.

Published in:

Annals of Neurology, 2004, v. 56, n. 4, p. 548, doi. 10.1002/ana.20224

By:

Richard A. Rudick;
Jar‐Chi Lee;
Jack Simon;
Richard M. Ransohoff;
Elizabeth Fisher

Publication type:

Article

Expression of CCR7 in multiple sclerosis: Implications for CNS immunity.

Published in:

Annals of Neurology, 2004, v. 55, n. 5, p. 627

By:

Pia Kivisäkk;
Don J. Mahad;
Melissa K. Callahan;
Keith Sikora;
Corinna Trebst;
Barbara Tucky;
Jerome Wujek;
Rivka Ravid;
Susan M. Staugaitis;
Hans Lassmann;
Richard M. Ransohoff

Publication type:

Article

Clinical neuroimmunology.

Published in:

Annals of Neurology, 1999, v. 46, n. 4, p. 679, doi. 10.1002/1531-8249(199910)46:4<679::AID-ANA21>3.0.CO;2-V

By:

Ransohoff, Richard M.

Publication type:

Article

Interferon beta induces interleukin-10 expression: Relevance to multiple sclerosis.

Published in:

Annals of Neurology, 1996, v. 40, n. 4, p. 618, doi. 10.1002/ana.410400412

By:

Rudick, Richard A.;
Ransohoff, Richard M.;
Peppler, Richard;
Medendorp, Sharon Vanderbrug;
Lehmann, Paul;
Alam, John

Publication type:

Article

The interferons: Biological effects, mechanisms of action, and use in multiple sclerosis.

Published in:

Annals of Neurology, 1995, v. 37, n. 1, p. 7, doi. 10.1002/ana.410370105

By:

Weinstock-Guttman, Bianca;
Ransohoff, Richard M.;
Kinkel, R. Philip;
Rudick, Richard A.

Publication type:

Article

Ccr2 deletion dissociates cavity size and tau pathology after mild traumatic brain injury.

Published in:

2015

By:

Gyoneva, Stefka;
Kim, Daniel;
Katsumoto, Atsuko;
Kokiko-Cochran, O. Nicole;
Lamb, Bruce T.;
Ransohoff, Richard M.

Publication type:

journal article

BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy.

Published in:

Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-10

By:

Pranzatelli, Michael R.;
Tate, Elizabeth D.;
McGee, Nathan R.;
Travelstead, Anna L.;
Colliver, Jerry A.;
Ness, Jayne M.;
Ransohoff, Richard M.

Publication type:

Article

BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy.

Published in:

2013

By:

Pranzatelli, Michael R;
Tate, Elizabeth D;
McGee, Nathan R;
Travelstead, Anna L;
Colliver, Jerry A;
Ness, Jayne M;
Ransohoff, Richard M

Publication type:

journal article

IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils.

Published in:

Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 104, doi. 10.1186/1742-2094-9-104

By:

Savarin, Carine;
Stohlman, Stephen A.;
Hinton, David R.;
Ransohoff, Richard M.;
Cua, Daniel J.;
Bergmann, Cornelia C.

Publication type:

Article

Human Brain Microvascular Endothelial Cells and Umbilical Vein Endothelial Cells Differentially Facilitate Leukocyte Recruitment and Utilize Chemokines for T Cell Migration.

Published in:

Clinical & Developmental Immunology, 2008, p. 1, doi. 10.1155/2008/384982

By:

Man, Shumei;
Ubogu, Eroboghene E.;
Williams, Katherine A.;
Tucky, Barbara;
Callahan, Melissa K.;
Ransohoff, Richard M.

Publication type:

Article

Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation.

Published in:

Immunological Reviews, 2000, v. 177, n. 1, p. 52, doi. 10.1034/j.1600-065x.2000.17709.x

By:

Huang, DeRen;
Han, Yulong;
Rani, M.R. Sadhya;
Glabinski, Andrzej;
Trebst, Corinna;
Sorensen, Torben;
Tani, Marie;
Jintang Wang;
Phil Chien;
O'Bryan, Sage;
Bielecki, Bartosz;
Zhihing Lucy Zhou;
Majumder, Sarmila;
Ransohoff, Richard M.

Publication type:

Article

A microglia clonal inflammatory disorder in Alzheimer's disease.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.96519

By:

Vicario, Rocio;
Fragkogianni, Stamatina;
Weber, Leslie;
Lazarov, Tomi;
Yang Hu;
Hayashi, Samantha Y.;
Craddock, Barbara;
Socci, Nicholas D.;
Alberdi, Araitz;
Baako, Ann;
Ay, Oyku;
Ogishi, Masato;
Lopez-Rodrigo, Estibaliz;
Kappagantula, Rajya;
Viale, Agnes;
Iacobuzio-Donahue, Christine A.;
Ting Zhou;
Ransohoff, Richard M.;
Chesworth, Richard;
Abdel-Wahab, Omar

Publication type:

Article

Neurodegeneration in Multiple Sclerosis: Relationship to Neurological Disability.

Published in:

Neuroscientist, 1999, v. 5, n. 1, p. 48, doi. 10.1177/107385849900500107

By:

Trapp, Bruce D.;
Ransohoff, Richard M.;
Fisher, Elizabeth;
Rudick, Richard A.

Publication type:

Article