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Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes.
Published in:
2019
By:
- Poulsen, K Harpelunde;
- Nielsen, J E;
- Frederiksen, H;
- Melau, C;
- Hare, K Juul;
- Thuesen, L Langhoff;
- Perlman, S;
- Lundvall, L;
- Mitchell, R T;
- Juul, A;
- Meyts, E Rajpert-De;
- Jørgensen, A;
- Harpelunde Poulsen, K;
- Juul Hare, K;
- Langhoff Thuesen, L;
- Rajpert-De Meyts, E
Publication type:
journal article
Decrease in semen quality and Leydig cell function in infertile men: a longitudinal study.
Published in:
2018
By:
- Olesen, I A;
- Joensen, U N;
- Petersen, J H;
- Almstrup, K;
- Meyts, E Rajpert-De;
- Carlsen, E;
- McLachlan, R;
- Juul, A;
- Jørgensen, N;
- Rajpert-De Meyts, E
Publication type:
journal article
AZFa protein DDX3Y is differentially expressed in human male germ cells during development and in testicular tumours: new evidence for phenotypic plasticity of germ cells.
Published in:
2012
By:
- Gueler B;
- Sonne SB;
- Zimmer J;
- Hilscher B;
- Hilscher W;
- Græm N;
- Rajpert-De Meyts E;
- Vogt PH;
- Gueler, B;
- Sonne, S B;
- Zimmer, J;
- Hilscher, B;
- Hilscher, W;
- Græm, N;
- Rajpert-De Meyts, E;
- Vogt, P H
Publication type:
journal article
DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.
Published in:
Oncogene, 2007, v. 26, n. 53, p. 7414, doi. 10.1038/sj.onc.1210553
By:
- Bartkova, J.;
- Hořej&#x0161, Z;
- Sehested, M.;
- Nesland, J. M.;
- Rajpert-De Meyts, E.;
- Skakkebæk, N. E.;
- Stucki, M.;
- Jackson, S.;
- Lukas, J.;
- Bartek, J.
Publication type:
Article
A simple screening method for detection of Klinefelter syndrome and other X-chromosome aneuploidies based on copy number of the androgen receptor gene.
Published in:
Molecular Human Reproduction, 2007, v. 13, n. 10, p. 745, doi. 10.1093/molehr/gam053
By:
- Ottesen, A.M.;
- Garn, I.D.;
- Aksglaede, L.;
- Juul, A.;
- Rajpert-De Meyts, E.
Publication type:
Article
High frequency of DAZ1/DAZ2 gene deletions in patients with severe oligozoospermia.
Published in:
Molecular Human Reproduction, 2002, v. 8, n. 3, p. 286, doi. 10.1093/molehr/8.3.286
By:
- Fernandes, S.;
- Huellen, K.;
- Goncalves, J.;
- Dukal, H.;
- Zeisler, J.;
- Rajpert De Meyts, E.;
- Skakkebaek, N.E.;
- Habermann, B.;
- Krause, W.;
- Sousa, M.;
- Barros, A.;
- Vogt, P.H.
Publication type:
Article
Short Report Cytogenetic and molecular analysis of a family with three brothers afflicted with germ-cell cancer.
Published in:
Clinical Genetics, 2004, v. 65, n. 1, p. 32, doi. 10.1111/j..2004.00180.x
By:
- Ottesen, A.M.;
- Rajpert-De Meyts, E.;
- Holm, M.;
- Andersen, I.-L.F.;
- Vogt, P.H.;
- Lundsteen, C.;
- Skakkebæk, N.E.
Publication type:
Article
Validation of endogenous normalizing genes for expression analyses in adult human testis and germ cell neoplasms.
Published in:
Molecular Human Reproduction, 2014, v. 20, n. 8, p. 709, doi. 10.1093/molehr/gau030
By:
- Svingen, T.;
- Jørgensen, A.;
- Rajpert-De Meyts, E.
Publication type:
Article
45,X/46,XY mosaicism: phenotypic characteristics, growth, and reproductive function--a retrospective longitudinal study.
Published in:
2012
By:
- Lindhardt Johansen M;
- Hagen CP;
- Rajpert-De Meyts E;
- Kjærgaard S;
- Petersen BL;
- Skakkebæk NE;
- Main KM;
- Juul A
Publication type:
Journal Article
Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours.
Published in:
2020
By:
- Harpelunde Poulsen, K.;
- Nielsen, J. E.;
- Grønkær Toft, B.;
- Joensen, U. N.;
- Rasmussen, L. J.;
- Blomberg Jensen, M.;
- Mitchell, R. T.;
- Juul, A.;
- Rajpert-De Meyts, E.;
- Jørgensen, A.
Publication type:
journal article
A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys.
Published in:
2009
By:
- Juul, A;
- Sørensen, K;
- Aksglaede, L;
- Garn, I;
- Rajpert-De Meyts, E;
- Hullstein, I;
- Hemmersbach, P;
- Ottesen, A M
Publication type:
journal article
Impaired Leydig Cell Function in Infertile Men: A Study of 357 Idiopathic Infertile Men and 318 Proven Fertile Controls.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 7, p. 3161, doi. 10.1210/jc.2003-031786
By:
- ANDERSSON, A.-M.;
- JøRGENSEN, N.;
- FRYDELUND-LARSEN, L.;
- MEYTS, E. RAJPERT-DE;
- SKAKKEBÆK, N. E.
Publication type:
Article
Double-blind Y chromosome microdeletion analysis in men with known sperm parameters and reproductive hormone profiles: microdeletions are specific for spermatogenic failure.
Published in:
2001
By:
- Krausz, C;
- Rajpert-De Meyts, E;
- Frydelund-Larsen, L;
- Quintana-Murci, L;
- McElreavey, K;
- Skakkebaek, N E
Publication type:
journal article
Are Male Reproductive Disorders a Common Entity?
Published in:
Annals of the New York Academy of Sciences, 2001, v. 948, n. 1, p. 90, doi. 10.1111/j.1749-6632.2001.tb03990.x
By:
- BOISEN, K. A.;
- MAIN, K. M.;
- RAJPERT-DE MEYTS, E.;
- SKAKKEBAEK, N. E.
Publication type:
Article
The relationship between Y chromosome DNA haplotypes and Y chromosome deletions leading to male infertility.
Published in:
Human Genetics, 2001, v. 108, n. 1, p. 55, doi. 10.1007/s004390000424
By:
- Quintana-Murci, L.;
- Krausz, C.;
- Heyer, E.;
- Gromoll, J.;
- Seifer, I.;
- Barton, D. E.;
- Barrett, T.;
- Skakkebaek, N. E.;
- Rajpert-De Meyts, E.;
- Mitchell, M.;
- Lee, A. C.;
- Jobling, M. A.;
- McElreavey, K.
Publication type:
Article
Goodbye International Journal of Andrology, welcome Andrology!
Published in:
Andrology, 2022, v. 10, p. 133, doi. 10.1111/andr.13251
By:
- Rajpert‐De Meyts, E.;
- Eliasson, R.;
- Comhaire, F. H.;
- Skakkebæk, N. E.;
- Sharpe, R. M.;
- Toppari, J.
Publication type:
Article
Goodbye International Journal of Andrology, welcome Andrology!
Published in:
Andrology, 2022, v. 10, p. 133, doi. 10.1111/andr.13251
By:
- Rajpert‐De Meyts, E.;
- Eliasson, R.;
- Comhaire, F. H.;
- Skakkebæk, N. E.;
- Sharpe, R. M.;
- Toppari, J.
Publication type:
Article
European Academy of Andrology (EAA) guidelines on investigation, treatment and monitoring of functional hypogonadism in males: Endorsing organization: European Society of Endocrinology.
Published in:
Andrology, 2020, v. 8, n. 5, p. 970, doi. 10.1111/andr.12770
By:
- Corona, Giovanni;
- Goulis, Dimitrios G.;
- Huhtaniemi, Ilpo;
- Zitzmann, Michael;
- Toppari, Jorma;
- Forti, Gianni;
- Vanderschueren, Dirk;
- Wu, Frederick C.;
- Corona, G.;
- Goulis, D.G.;
- Forti, G.;
- Behre, H.M.;
- Punab, M.;
- Toppari, J.;
- Krausz, C.;
- Rajpert‐De Meyts, E;
- Tüttelmann, F;
- Isidori, A.M.;
- Ruiz‐Castane, E;
- Jezek, D
Publication type:
Article
Testicular germ cell cancer: recent developments in biology and clinical management.
Published in:
2019
By:
- Rajpert‐De Meyts, E.
Publication type:
Editorial
Quantification of the Leydig cell compartment in testicular biopsies and association with biochemical Leydig cell dysfunction in testicular cancer survivors.
Published in:
Andrology, 2018, v. 6, n. 5, p. 748, doi. 10.1111/andr.12508
By:
- Tarsitano, M. G.;
- Bandak, M.;
- Jørgensen, N.;
- Skakkebæk, N. E.;
- Juul, A.;
- Lenzi, A.;
- Daugaard, G.;
- Rajpert‐De Meyts, E.
Publication type:
Article
Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?
Published in:
Andrology, 2018, v. 6, n. 1, p. 176, doi. 10.1111/andr.12440
By:
- Bang, A. K.;
- Busch, A. S.;
- Almstrup, K.;
- Gromoll, J.;
- Kliesch, S.;
- Rajpert‐De Meyts, E.;
- Skakkebæk, N. E.;
- Juul, A.;
- Tüttelmann, F.;
- Jørgensen, N.
Publication type:
Article
Possible involvement of the glucocorticoid receptor ( NR3C1) and selected NR3C1 gene variants in regulation of human testicular function.
Published in:
Andrology, 2017, v. 5, n. 6, p. 1105, doi. 10.1111/andr.12418
By:
- Nordkap, L.;
- Almstrup, K.;
- Nielsen, J. E.;
- Bang, A. K.;
- Priskorn, L.;
- Krause, M.;
- Holmboe, S. A.;
- Winge, S. B.;
- Egeberg Palme, D. L.;
- Mørup, N.;
- Petersen, J. H.;
- Juul, A.;
- Skakkebæk, N. E.;
- Rajpert‐De Meyts, E.;
- Jørgensen, N.
Publication type:
Article
Rewarding peer-review work: the Publons initiative.
Published in:
Andrology, 2016, v. 4, n. 6, p. 985, doi. 10.1111/andr.12301
By:
- Rajpert‐De Meyts, E.;
- Losito, S.;
- Carrell, D. T.
Publication type:
Article
Special issue on endocrine disruption and reproductive health.
Published in:
2016
By:
- Rajpert‐De Meyts, E.;
- Carrell, D. T.
Publication type:
Editorial
Cellular correlates of selfish spermatogonial selection.
Published in:
Andrology, 2016, v. 4, n. 3, p. 550, doi. 10.1111/andr.12185
By:
- Maher, G. J.;
- Rajpert‐De Meyts, E.;
- Goriely, A.;
- Wilkie, A. O. M.
Publication type:
Article
Andrology Award 2015.
Published in:
2016
By:
- Rajpert‐De Meyts, E.;
- Carrell, D. T.
Publication type:
Editorial
Announcing the 2014 Andrology Award.
Published in:
2015
By:
- Carrell, D. T.;
- Rajpert‐De Meyts, E.
Publication type:
Editorial
Increasing international efforts to understand and conquer testicular germ cell cancer.
Published in:
2015
By:
- Rajpert‐De Meyts, E.;
- Daugaard, G.;
- Almstrup, K.;
- Jørgensen, A.;
- Rørth, M.;
- Jørgensen, N.;
- Maase, H.;
- Skakkebaek, N. E.
Publication type:
Editorial
Contralateral biopsy in the management of testicular cancer: what we have learned and what we need to improve.
Published in:
2015
By:
- Rørth, M.;
- Grigor, K. M.;
- Jørgensen, N.;
- Skakkebaek, N. E.;
- Rajpert‐De Meyts, E.
Publication type:
Editorial
A survey of etiologic hypotheses among testicular cancer researchers.
Published in:
Andrology, 2015, v. 3, n. 1, p. 19, doi. 10.1111/andr.306
By:
- Stang, A.;
- Trabert, B.;
- Rusner, C.;
- Poole, C.;
- Almstrup, K.;
- Rajpert‐De Meyts, E.;
- McGlynn, K. A.
Publication type:
Article
The need of continuous focus on improved mentoring of trainees and young investigators in the field of andrology: highlights of current programs and opportunities for the future.
Published in:
2014
By:
- Carrell, D. T.;
- Rajpert‐De Meyts, E.;
- Krausz, C.;
- Jannini, E. A.;
- Liu, P. Y.;
- Gerton, G. L.;
- La Salle, S.;
- Amaral, A.
Publication type:
Editorial
A novel double staining strategy for improved detection of testicular carcinoma in situ cells in human semen samples.
Published in:
Andrologia, 2012, v. 44, n. 2, p. 78, doi. 10.1111/j.1439-0272.2010.01108.x
By:
- Nielsen, J. E.;
- Kristensen, D. M.;
- Almstrup, K.;
- Jørgensen, A.;
- Olesen, I. A.;
- Jacobsen, G. K.;
- Horn, T.;
- Skakkebæk, N. E.;
- Leffers, H.;
- Rajpert-De Meyts, E.
Publication type:
Article
Frequent DAZ1/DAZ2 deletions in men with severe oligozoospermia.
Published in:
Andrologia, 2003, v. 35, n. 1, p. 5, doi. 10.1046/j.1439-0272.2003.00531_7.x
By:
- Fernandes, S.;
- Goncalves, J.;
- Hüllen, K.;
- Zeisler, J.;
- Rajpert De Meyts, E.;
- Skakkebaek, N. E.;
- Habermann, B.;
- Krause, W.;
- Barros, A.;
- Vogt, P. H.
Publication type:
Article
The expression of CD44 adhesion molecules on seminoma cells. A new marker for early detection of the tumor.
Published in:
1996
By:
- Rajpert-De Meyts, Ewa;
- Skakkebaek, Niels E.;
- Rajpert-De Meyts, E;
- Skakkebaek, N E
Publication type:
Letter
Factor V Leiden is associated with increased sperm count.
Published in:
2017
By:
- van Mens, T. E.;
- Joensen, U. N.;
- Bochdanovits, Z.;
- Takizawa, A.;
- Peter, J.;
- Jørgensen, N.;
- Szecsi, P. B.;
- Meijers, J. C. M.;
- Weiler, H.;
- Rajpert-De Meyts, E.;
- Repping, S.;
- Middeldorp, S.
Publication type:
journal article
Ex vivo culture of human fetal gonads: manipulation of meiosis signalling by retinoic acid treatment disrupts testis development.
Published in:
2015
By:
- Jørgensen, A.;
- Nielsen, J. E.;
- Perlman, S.;
- Lundvall, L.;
- Mitchell, R. T.;
- Juul, A.;
- Rajpert-De Meyts, E.
Publication type:
journal article
Expression patterns of DLK1 and INSL3 identify stages of Leydig cell differentiation during normal development and in testicular pathologies, including testicular cancer and Klinefelter syndrome.
Published in:
Human Reproduction, 2014, v. 29, n. 8, p. 1637, doi. 10.1093/humrep/deu124
By:
- Lottrup, G.;
- Nielsen, J.E.;
- Maroun, L.L.;
- Møller, L.M.A.;
- Yassin, M.;
- Leffers, H.;
- Skakkebæk, N.E.;
- Rajpert-De Meyts, E.
Publication type:
Article
AZFa protein DDX3Y is differentially expressed in human male germ cells during development and in testicular tumours: new evidence for phenotypic plasticity of germ cells ‡.
Published in:
Human Reproduction, 2012, v. 27, n. 6, p. 1547, doi. 10.1093/humrep/des047
By:
- Gueler, B.;
- Sonne, S.B.;
- Zimmer, J.;
- Hilscher, B.;
- Hilscher, W.;
- Græm, N.;
- Rajpert-De Meyts, E.;
- Vogt, P.H.
Publication type:
Article
Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster.
Published in:
2007
By:
- Novotny, G. W.;
- Sonne, S. B.;
- Nielsen, J. E.;
- Jonstrup, S. P.;
- Hansen, M. A.;
- Skakkebaek, N. E.;
- Meyts, E. Rajpert-De;
- Kjems, J.;
- Leffers, H.
Publication type:
Letter
MAGE-A4, a germ cell specific marker, is expressed differentially in testicular tumors.
Published in:
2001
By:
- Aubry, Florence;
- Satie, Anne-Pascale;
- Rioux-Leclercq, Nathalie;
- Rajpert-De Meyts, Ewa;
- Spagnoli, Giulio C.;
- Chomez, Patrick;
- De Backer, Olivier;
- Jégou, Bernard;
- Samson, Michel;
- Aubry, F;
- Satie, A P;
- Rioux-Leclercq, N;
- Rajpert-De Meyts, E;
- Spagnoli, G C;
- Chomez, P;
- De Backer, O;
- Jégou, B;
- Samson, M
Publication type:
journal article
Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours.
Published in:
Histopathology, 2005, v. 47, n. 1, p. 48, doi. 10.1111/j.1365-2559.2005.02182.x
By:
- Hoei-Hansen, C. E.;
- Almstrup, K.;
- Nielsen, J. E.;
- Brask Sonne, S.;
- Graem, N.;
- Skakkebaek, N. E.;
- Leffers, H.;
- Rajpert-De Meyts, E.
Publication type:
Article
Hanging drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche.
Published in:
British Journal of Cancer, 2014, v. 110, n. 10, p. 2604, doi. 10.1038/bjc.2014.160
By:
- Jørgensen, A;
- Young, J;
- Nielsen, J E;
- Joensen, U N;
- Toft, B G;
- Rajpert-De Meyts, E;
- Loveland, K L
Publication type:
Article
Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis.
Published in:
2014
By:
- Kristensen, D G;
- Nielsen, J E;
- Jørgensen, A;
- Skakkebæk, N E;
- Rajpert-De Meyts, E;
- Almstrup, K
Publication type:
journal article
Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis.
Published in:
British Journal of Cancer, 2014, v. 110, n. 3, p. 668, doi. 10.1038/bjc.2013.727
By:
- Kristensen, D G;
- Nielsen, J E;
- Jørgensen, A;
- Skakkebæk, N E;
- Rajpert-De Meyts, E;
- Almstrup, K
Publication type:
Article
Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells.
Published in:
2010
By:
- Almstrup, Kristian;
- Nielsen, J. E.;
- Mlynarska, O.;
- Jansen, M. T.;
- Jørgensen, A.;
- Skakkebæk, N. E.;
- Rajpert-De Meyts, E.;
- Almstrup, K;
- Jørgensen, A;
- Skakkebæk, N E
Publication type:
journal article
Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number.
Published in:
Human Reproduction, 2008, v. 23, n. 7, p. 1669, doi. 10.1093/humrep/den124
By:
- C. Mau Kai;
- A. Juul;
- K. McElreavey;
- A.M. Ottesen;
- I.D. Garn;
- K.M. Main;
- A. Loft;
- N. Jørgensen;
- N.E. Skakkebæk;
- A. Nyboe Andersen;
- E. Rajpert-De Meyts
Publication type:
Article
Activin receptor subunits in normal and dysfunctional adult human testis.
Published in:
Human Reproduction, 2008, v. 23, n. 2, p. 412
By:
- V. Dias;
- S. Meachem;
- E. Rajpert-De Meyts;
- R. McLachlan;
- U. Manuelpillai;
- K.L. Loveland
Publication type:
Article
Preserved fertility in a non-mosaic Klinefelter patient with a mutation in the fibroblast growth factor receptor 3 gene: Case Report.
Published in:
Human Reproduction, 2007, v. 22, n. 7, p. 1907, doi. 10.1093/humrep/dem126
By:
- A. Juul;
- L. Aksglaede;
- A.M. Lund;
- M. Duno;
- N.E. Skakkebæk;
- E. Rajpert-De Meyts
Publication type:
Article
Histological evaluation of the human testis—approaches to optimizing the clinical value of the assessment: Mini Review.
Published in:
Human Reproduction, 2007, v. 22, n. 1, p. 2, doi. 10.1093/humrep/del279
By:
- R.I. McLachlan;
- E. Rajpert-De Meyts;
- C.E. Hoei-Hansen;
- D.M. de Kretser;
- N.E. Skakkebaek
Publication type:
Article
A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2? in semen samples: Case report.
Published in:
Human Reproduction, 2005, v. 20, n. 3, p. 579, doi. 10.1093/humrep/deh759
By:
- C.E. Hoei-Hansen;
- E. Rajpert-De Meyts;
- E. Carlsen;
- K. Almstrup;
- H. Leffers;
- N.E. Skakkebaek
Publication type:
Article

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