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The SMAC mimetic AT-101 exhibits anti-tumor and antimetastasis activity in lung adenocarcinoma cells by the IAPs/caspase-dependent apoptosis and p65-NFκB cross-talk.
- Published in:
- Iranian Journal of Basic Medical Sciences, 2021, v. 24, n. 7, p. 969, doi. 10.22038/ijbms.2021.56400.12586
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- Publication type:
- Article
Anti-Cancer Activity of Ethanolic Leaf Extract of Salvia officinalis against Oral Squamous Carcinoma Cells in vitro via Caspase Mediated Mitochondrial Apoptosis.
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- Pharmacognosy Magazine, 2020, v. 16, p. S546, doi. 10.4103/pm.pm_90_20
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- Publication type:
- Article
IOX-101, a novel small molecule, reduces AML cell proliferation by Akt enzyme inhibition.
- Published in:
- Archives of Biological Sciences, 2018, v. 70, n. 2, p. 321, doi. 10.2298/ABS170922049R
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- Publication type:
- Article
Computational and in vitro characterization of ICY‐5: A potential candidate promoting mitochondrial apoptosis via the c‐MET and STAT3 pathways.
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- Journal of Cellular Physiology, 2021, v. 236, n. 1, p. 146, doi. 10.1002/jcp.29830
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- Publication type:
- Article
A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro.
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- Cancer Research & Treatment, 2015, v. 47, n. 4, p. 913, doi. 10.4143/crt.2014.057
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- Publication type:
- Article
Indirubin-3-monoxime and thymoquinone exhibit synergistic efficacy as therapeutic combination in in-vitro and in-vivo models of Lung cancer.
- Published in:
- Archives of Pharmacal Research, 2020, v. 43, n. 6, p. 655, doi. 10.1007/s12272-020-01241-2
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- Publication type:
- Article
IOX-101 Reverses Drug Resistance Through Suppression of Akt/mTOR/NF-κB Signaling in Cancer Stem Cell-Like, Sphere-Forming NSCLC Cell.
- Published in:
- Oncology Research, 2020, v. 28, n. 2, p. 177, doi. 10.3727/096504019X15746768080428
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- Publication type:
- Article
FCY-302, a Novel Small Molecule, Induces Apoptosis in Leukemia and Myeloma Cells by Attenuating Key Antioxidant and Mitochondrial Enzymes.
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- Oncology Research, 2019, v. 27, n. 8, p. 957, doi. 10.3727/096504019X15555428221646
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- Publication type:
- Article
GC/MS characterization and computational kinome‐wide screening of pomegranate fruit extract identifies key phytochemicals interacting to CDK kinases implicated in acute myeloid leukemia cells.
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- Journal of Food Biochemistry, 2022, v. 46, n. 8, p. 1, doi. 10.1111/jfbc.14178
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- Publication type:
- Article
Glucose and oleic acid mediate cellular alterations in GLP‐1‐induced insulin‐positive differentiating UCBMSCs.
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- Journal of Food Biochemistry, 2022, v. 46, n. 5, p. 1, doi. 10.1111/jfbc.14087
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- Publication type:
- Article
Cassia auriculata leaf extract ameliorates diabetic nephropathy by attenuating autophagic necroptosis via RIP‐1/RIP‐3‐p‐p38MAPK signaling.
- Published in:
- Journal of Food Biochemistry, 2021, v. 45, n. 7, p. 1, doi. 10.1111/jfbc.13810
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- Publication type:
- Article
Thymoquinone (Tq) protects necroptosis induced by autophagy/mitophagy‐dependent oxidative stress in human bronchial epithelial cells exposed to cigarette smoke extract (CSE).
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- Journal of Food Biochemistry, 2020, v. 44, n. 9, p. 1, doi. 10.1111/jfbc.13366
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- Publication type:
- Article
Thymoquinone attenuates IgE‐mediated allergic response via pi3k‐Akt‐NFκB pathway and upregulation of the Nrf2‐HO1 axis.
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- Journal of Food Biochemistry, 2020, v. 44, n. 6, p. 1, doi. 10.1111/jfbc.13216
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- Publication type:
- Article
Rational combinations of indirubin and arylidene derivatives exhibit synergism in human non‐small cell lung carcinoma cells.
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- Journal of Food Biochemistry, 2019, v. 43, n. 7, p. N.PAG, doi. 10.1111/jfbc.12861
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- Article
Thymoquinone attenuates phosphorylation of AKT to inhibit kidney cancer cell proliferation.
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- Journal of Food Biochemistry, 2019, v. 43, n. 4, p. N.PAG, doi. 10.1111/jfbc.12793
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- Publication type:
- Article
FPX-113 attenuates inflammatory responses by deteriorating cytokines, neutrophil activity and mast cell degranulation via Akt/ NF- κB pathway.
- Published in:
- Biologia, 2020, v. 75, n. 3, p. 447, doi. 10.2478/s11756-019-00367-z
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- Article
Antimicrobial Efficiency of Essential Oils from Traditional Medicinal Plants of Asir Region, Saudi Arabia, over Drug Resistant Isolates.
- Published in:
- BioMed Research International, 2019, p. 1, doi. 10.1155/2019/8928306
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- Publication type:
- Article
Synergistic efficacies of thymoquinone and standard antibiotics against multi-drug resistant isolates.
- Published in:
- Saudi Medical Journal, 2021, v. 42, n. 2, p. 196, doi. 10.15537/smj.2021.2.25706
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- Publication type:
- Article
High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma.
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- Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 12, p. 1165, doi. 10.1007/s10822-021-00426-1
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- Article
Feasibility of cord blood bank in high altitude Abha: preclinical impacts.
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- 2018
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- Publication type:
- journal article
Biological evaluation of 2-arylidene-4, 7-dimethyl indan-1-one (FXY-1): a novel Akt inhibitor with potent activity in lung cancer.
- Published in:
- 2016
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- Publication type:
- journal article
Chamomile and oregano extracts synergistically exhibit antihyperglycemic, antihyperlipidemic, and renal protective effects in alloxan-induced diabetic rats.
- Published in:
- Canadian Journal of Physiology & Pharmacology, 2017, v. 95, n. 1, p. 84, doi. 10.1139/cjpp-2016-0189
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- Publication type:
- Article
Antiproliferative and anticancer activities of Neurada procumbens L. against epithelial carcinoma and breast cancer cell lines.
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- Indian Journal of Experimental Biology, 2022, v. 60, n. 5, p. 308
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- Publication type:
- Article
BV6 enhances apoptosis in Lung cancer cells by ameliorating caspase expressions through attenuation of XIAP, cIAP-1, and cIAP-2 proteins.
- Published in:
- 2022
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- Publication type:
- journal article
FCX, an arylidene derivative, induces apoptosis in androgen receptor-selective prostate cancer cells.
- Published in:
- 2021
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- Publication type:
- journal article
MSCs ameliorates DPN induced cellular pathology via [Ca<sup>2+</sup>]<sub>i</sub> homeostasis and scavenging the pro-inflammatory cytokines.
- Published in:
- Journal of Cellular Physiology, 2018, v. 233, n. 2, p. 1330, doi. 10.1002/jcp.26009
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- Publication type:
- Article
Computational analysis and in vitro evaluation of TMF 104, for its antioxidant, antimicrobial, and anticancer efficacies.
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- Biotechnology & Applied Biochemistry, 2023, v. 70, n. 1, p. 148, doi. 10.1002/bab.2337
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- Publication type:
- Article
Thymoquinone inhibits IL‐7‐induced tumor progression and metastatic invasion in prostate cancer cells by attenuating matrix metalloproteinase activity and Akt/NF‐κB signaling.
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- Biotechnology & Applied Biochemistry, 2021, v. 68, n. 6, p. 1403, doi. 10.1002/bab.2062
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- Article
FCX‐146, a potent allosteric inhibitor of Akt kinase in cancer cells: Lead optimization of the second‐generation arylidene indanone scaffold.
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- Biotechnology & Applied Biochemistry, 2021, v. 68, n. 1, p. 82, doi. 10.1002/bab.1896
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- Publication type:
- Article
Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+]i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro.
- Published in:
- Cells (2073-4409), 2018, v. 7, n. 12, p. 250, doi. 10.3390/cells7120250
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- Publication type:
- Article
High-throughput computational screening and in vitro evaluation identifies 5-(4-oxo-4H-3,1-benzoxazin-2-yl)-2-[3-(4-oxo-4H-3,1-benzoxazin-2-yl) phenyl]-1H-isoindole-1,3(2H)-dione (C3), as a novel EGFR--HER2 dual inhibitor in gastric tumors.
- Published in:
- Oncology Research, 2024, v. 32, n. 2, p. 251, doi. 10.32604/or.2023.043139
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- Publication type:
- Article
Computational high-throughput screening and in vitro approaches identify CB-006-3; A novel PI3K-BRAF<sup>V600E</sup> dual targeted inhibitor against melanoma.
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- Oncology Research, 2021, v. 29, n. 5, p. 305, doi. 10.32604/or.2022.025187
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- Article
Computational docking and in vitro analysis identifies novel arylidene analogue FPMXY-14 against renal cancer cells by attenuating Akt.
- Published in:
- Oncology Research, 2021, v. 29, n. 3, p. 217, doi. 10.32604/or.2022.03570
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- Publication type:
- Article
Anticancer efficacy of 3-(4-isopropyl) benzylidene-8-ethoxy, 6-methyl, chroman-4-one (SBL-060), a novel, dual, estrogen receptor-Akt kinase inhibitor in acute myeloid leukemia cells.
- Published in:
- Oncology Research, 2021, v. 29, n. 3, p. 149, doi. 10.32604/or.2022.03539
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- Publication type:
- Article
A Combined Chemical, Computational, and In Vitro Approach Identifies SBL-105 as Novel DHODH Inhibitor in Acute Myeloid Leukemia Cells.
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- Oncology Research, 2020, v. 28, n. 9, p. 899, doi. 10.3727/096504021X16281573507558
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- Article
Body Mass Index and Its Association with Genetically Transmitted Traits.
- Published in:
- BioMed Research International, 2020, p. 1, doi. 10.1155/2020/3469316
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- Publication type:
- Article
Secondary Metabolites of Saussurea costus Leaf Extract Induce Apoptosis in Breast, Liver, and Colon Cancer Cells by Caspase-3-Dependent Intrinsic Pathway.
- Published in:
- BioMed Research International, 2020, p. 1, doi. 10.1155/2020/1608942
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- Publication type:
- Article
Insilco and Invitro approaches identify novel dual PI3K/AKT pathway inhibitors to control acute myeloid leukemia cell proliferations.
- Published in:
- 2022
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- Publication type:
- journal article
Thymoquinone attenuates oxidative stress of kidney mitochondria and exerts nephroprotective effects in oxonic acid‐induced hyperuricemia rats.
- Published in:
- Biofactors, 2020, v. 46, n. 2, p. 292, doi. 10.1002/biof.1590
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- Publication type:
- Article
Synthesis and Application of Carbonated Fatty Acid Esters from Carbon Dioxide Including a Life Cycle Analysis.
- Published in:
- ChemSusChem, 2014, v. 7, n. 4, p. 1133, doi. 10.1002/cssc.201301115
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- Article