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Doxycycline and its derivative, COL-3, decrease dyskinesia induced by l-DOPA in hemiparkinsonian rats.
- Published in:
- 2021
- By:
- Publication type:
- journal article
The Pesticide Chlordecone Promotes Parkinsonism-like Neurodegeneration with Tau Lesions in Midbrain Cultures and C. elegans Worms.
- Published in:
- Cells (2073-4409), 2023, v. 12, n. 9, p. 1336, doi. 10.3390/cells12091336
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- Publication type:
- Article
Neuroprotective Effects of a Novel Demeclocycline Derivative Lacking Antibiotic Activity: From a Hit to a Promising Lead Compound.
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- Cells (2073-4409), 2022, v. 11, n. 17, p. 2759, doi. 10.3390/cells11172759
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- Publication type:
- Article
The Chemically-Modified Tetracycline COL-3 and Its Parent Compound Doxycycline Prevent Microglial Inflammatory Responses by Reducing Glucose-Mediated Oxidative Stress.
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- Cells (2073-4409), 2021, v. 10, n. 8, p. 2163, doi. 10.3390/cells10082163
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- Publication type:
- Article
Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates.
- Published in:
- Cells (2073-4409), 2019, v. 8, n. 8, p. 776, doi. 10.3390/cells8080776
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- Publication type:
- Article
Investigations into potential extrasynaptic communication between the dopaminergic and nitrergic systems.
- Published in:
- Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00372
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- Publication type:
- Article
Glycosaminoglycans from Alzheimer’s disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau.
- Published in:
- PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0209573
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- Publication type:
- Article
Pleiotrophin receptor RPTP-ζ/β expression is up-regulated byl-DOPA in striatal medium spiny neurons of parkinsonian rats.
- Published in:
- Journal of Neurochemistry, 2008, v. 107, n. 2, p. 443, doi. 10.1111/j.1471-4159.2008.05640.x
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- Publication type:
- Article
Donepezil induces a cholinergic sprouting in basocortical degeneration.
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- Journal of Neurochemistry, 2007, v. 102, n. 2, p. 434, doi. 10.1111/j.1471-4159.2007.04497.x
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- Publication type:
- Article
Monoamine transporter inhibitors and norepinephrine reduce dopamine-dependent iron toxicity in cells derived from the substantia nigra.
- Published in:
- Journal of Neurochemistry, 2005, v. 92, n. 5, p. 1021, doi. 10.1111/j.1471-4159.2004.02931.x
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- Publication type:
- Article
The Alpha2-Adrenoceptor Antagonist Dexefaroxan Enhances Hippocampal Neurogenesis by Increasing the Survival and Differentiation of New Granule Cells.
- Published in:
- Neuropsychopharmacology, 2006, v. 31, n. 6, p. 1146, doi. 10.1038/sj.npp.1300954
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- Publication type:
- Article
Self-evolving oxidative stress with identifiable pre- and postmitochondrial phases in PC12 cells.
- Published in:
- Journal of Neuroscience Research, 2013, v. 91, n. 2, p. 273, doi. 10.1002/jnr.23146
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- Publication type:
- Article
Elevated serotonin is involved in hyperactivity but not in the paradoxical effect of amphetamine in mice neonatally lesioned with 6‐hydroxydopamine.
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- Journal of Neuroscience Research, 2004, v. 78, n. 2, p. 289, doi. 10.1002/jnr.20245
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- Publication type:
- Article
Front Cover: C9‐Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α‐Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration (ChemMedChem 12/2024).
- Published in:
- ChemMedChem, 2024, v. 19, n. 12, p. 1, doi. 10.1002/cmdc.202481201
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- Publication type:
- Article
C9‐Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α‐Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration.
- Published in:
- ChemMedChem, 2024, v. 19, n. 12, p. 1, doi. 10.1002/cmdc.202300597
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- Publication type:
- Article
Succinobucol, a Non-Statin Hypocholesterolemic Drug, Prevents Premotor Symptoms and Nigrostriatal Neurodegeneration in an Experimental Model of Parkinson's Disease.
- Published in:
- Molecular Neurobiology, 2017, v. 54, n. 2, p. 1513, doi. 10.1007/s12035-016-9747-z
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- Publication type:
- Article
Parkin immunoreactivity in the brain of human and non-human primates: An immunohistochemical analysis in normal conditions and in Parkinsonian syndromes.
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- Journal of Comparative Neurology, 2001, v. 432, n. 2, p. 184, doi. 10.1002/cne.1096
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- Publication type:
- Article
Altered development of dopaminergic cells in the retina of weaver mice.
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- Journal of Comparative Neurology, 1999, v. 412, n. 4, p. 656, doi. 10.1002/(SICI)1096-9861(19991004)412:4<656::AID-CNE7>3.0.CO;2-9
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- Publication type:
- Article
Tetracycline repurposing in neurodegeneration: focus on Parkinson’s disease.
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- Journal of Neural Transmission, 2018, v. 125, n. 10, p. 1403, doi. 10.1007/s00702-018-1913-1
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- Publication type:
- Article
Differential gene expression induced by chronic levodopa treatment in the striatum of rats with lesions of the nigrostriatal system.
- Published in:
- Journal of Neurochemistry, 2004, v. 90, n. 6, p. 1348, doi. 10.1111/j.1471-4159.2004.02595.x
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- Publication type:
- Article
Cloning of Rat Parkin cDNA and Distribution of Parkin in Rat Brain.
- Published in:
- Journal of Neurochemistry, 2000, v. 74, n. 4, p. 1773, doi. 10.1046/j.1471-4159.2000.0741773.x
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- Publication type:
- Article
Systemic Administration of NMDA and AMPA Receptor Antagonists Reverses the Neurochemical Changes Induced by Nigrostriatal Denervation in Basal Ganglia.
- Published in:
- Journal of Neurochemistry, 1999, v. 73, n. 1, p. 344, doi. 10.1046/j.1471-4159.1999.0730344.x
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- Publication type:
- Article
Long-Term Induction of Tyrosine Hydroxylase Expression: Compensatory Response to Partial Degeneration of the Dopaminergic Nigrostriatal System in the Rat Brain.
- Published in:
- Journal of Neurochemistry, 1995, v. 64, n. 4, p. 1669, doi. 10.1046/j.1471-4159.1995.64041669.x
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- Publication type:
- Article
Cellular Quantification of Tyrosine Hydroxylase in the Rat Brain by Immunoautoradiography.
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- Journal of Neurochemistry, 1993, v. 61, n. 2, p. 617, doi. 10.1111/j.1471-4159.1993.tb02166.x
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- Publication type:
- Article
Quantitative Autoradiography of Tyrosine Hydroxylase Immunoreactivity in the Rat Brain.
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- Journal of Neurochemistry, 1991, v. 57, n. 4, p. 1212, doi. 10.1111/j.1471-4159.1991.tb08282.x
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- Publication type:
- Article
De novo tetrahydrobiopterin biosynthesis is impaired in the inflammed striatum of parkin(<sup>-/-</sup>) mice.
- Published in:
- Cell Biology International, 2018, v. 42, n. 6, p. 725, doi. 10.1002/cbin.10969
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- Publication type:
- Article
Moderate-Intensity Physical Exercise Protects Against Experimental 6-Hydroxydopamine-Induced Hemiparkinsonism Through Nrf2-Antioxidant Response Element Pathway.
- Published in:
- Neurochemical Research, 2016, v. 41, n. 1/2, p. 64, doi. 10.1007/s11064-015-1709-8
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- Publication type:
- Article
P4-378: Effects of donepezil against degeneration of the basalocortical cholinergic system induced by cortical devascularisation in the adult rat
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P4-378: Effects of donepezil against degeneration of the basalocortical cholinergic system induced by cortical devascularisation in the adult rat
- Published in:
- 2006
- By:
- Publication type:
- Abstract
New Roles of Glycosaminoglycans in α-Synuclein Aggregation in a Cellular Model of Parkinson Disease.
- Published in:
- PLoS ONE, 2015, v. 10, n. 1, p. 1, doi. 10.1371/journal.pone.0116641
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- Publication type:
- Article
Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease.
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- PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114216
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- Publication type:
- Article
Chemicals Possessing a Neurotrophin-Like Activity on Dopaminergic Neurons in Primary Culture.
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- PLoS ONE, 2009, v. 4, n. 7, p. 1, doi. 10.1371/journal.pone.0006215
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- Publication type:
- Article
The two synthetic cannabinoid compounds 4′‐F‐CBD and HU‐910 efficiently restrain inflammatory responses of brain microglia and astrocytes.
- Published in:
- Glia, 2024, v. 72, n. 3, p. 529, doi. 10.1002/glia.24489
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- Publication type:
- Article
Cannabidiol prevents LPS‐induced microglial inflammation by inhibiting ROS/NF‐κB‐dependent signaling and glucose consumption.
- Published in:
- Glia, 2020, v. 68, n. 3, p. 561, doi. 10.1002/glia.23738
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- Publication type:
- Article
Microglial glutamate release evoked by α‐synuclein aggregates is prevented by dopamine.
- Published in:
- Glia, 2018, v. 66, n. 11, p. 2353, doi. 10.1002/glia.23472
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- Publication type:
- Article
A simplified approach for efficient isolation of functional microglial cells: Application for modeling neuroinflammatory responses in vitro.
- Published in:
- Glia, 2016, v. 64, n. 11, p. 1912, doi. 10.1002/glia.23032
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- Publication type:
- Article
Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species.
- Published in:
- Scientific Reports, 2017, p. 41755, doi. 10.1038/srep41755
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- Publication type:
- Article
Contributive Role of TNF-α to L-DOPA-Induced Dyskinesia in a Unilateral 6-OHDA Lesion Model of Parkinson's Disease.
- Published in:
- Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.617085
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- Publication type:
- Article
Repurposing an established drug: an emerging role for methylene blue in L‐DOPA‐induced dyskinesia.
- Published in:
- European Journal of Neuroscience, 2019, v. 49, n. 6, p. 869, doi. 10.1111/ejn.14079
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- Publication type:
- Article
Repurposing an established drug: an emerging role for methylene blue in L‐DOPA‐induced dyskinesia.
- Published in:
- European Journal of Neuroscience, 2019, v. 49, n. 5, p. 869, doi. 10.1111/ejn.14079
- By:
- Publication type:
- Article
Aminochrome induces dopaminergic neuronal dysfunction: a new animal model for Parkinson's disease.
- Published in:
- Cellular & Molecular Life Sciences, 2016, v. 73, n. 18, p. 3583, doi. 10.1007/s00018-016-2182-5
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- Publication type:
- Article
CMT-3 targets different α-synuclein aggregates mitigating their toxic and inflammogenic effects.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-76927-0
- By:
- Publication type:
- Article
Doxycycline attenuates L-DOPA-induced dyskinesia through an anti-inflammatory effect in a hemiparkinsonian mouse model.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1045465
- By:
- Publication type:
- Article
Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity.
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. N.PAG, doi. 10.3389/fnagi.2021.635760
- By:
- Publication type:
- Article
Mice with genetic deletion of the heparin-binding growth factor midkine exhibit early preclinical features of Parkinson's disease.
- Published in:
- Journal of Neural Transmission, 2011, v. 118, n. 8, p. 1215, doi. 10.1007/s00702-010-0568-3
- By:
- Publication type:
- Article
Oxidative Stress Caused by Ozone Exposure Induces Loss of Brain Repair in the Hippocampus of Adult Rats.
- Published in:
- Toxicological Sciences, 2010, v. 113, n. 1, p. 187, doi. 10.1093/toxsci/kfp252
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- Publication type:
- Article
HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology.
- Published in:
- Brain: A Journal of Neurology, 2015, v. 138, n. 5, p. 1339, doi. 10.1093/brain/awv056
- By:
- Publication type:
- Article
l-DOPA-induced dyskinesia in Parkinson's disease: Are neuroinflammation and astrocytes key elements?
- Published in:
- Synapse, 2016, v. 70, n. 12, p. 479, doi. 10.1002/syn.21941
- By:
- Publication type:
- Article
Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions.
- Published in:
- Annals of Neurology, 1998, v. 43, n. 5, p. 561, doi. 10.1002/ana.410430504
- By:
- Publication type:
- Article
The Neuroprotective Effect of Doxycycline on Neurodegenerative Diseases.
- Published in:
- Neurotoxicity Research, 2019, v. 35, n. 4, p. 981, doi. 10.1007/s12640-019-00015-z
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- Publication type:
- Article