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Development of Novel Tools for Dissection of Central Versus Peripheral Dopamine D<sub>2</sub>-Like Receptor Signaling in Dysglycemia.
- Published in:
- Diabetes, 2024, v. 73, n. 9, p. 1411, doi. 10.2337/db24-0175
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- Publication type:
- Article
Inhibition of EV biogenesis reduces tau propagation in Alzheimer's Disease mouse models.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.078341
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- Article
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer's disease mouse model.
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- Translational Neurodegeneration, 2023, v. 12, n. 1, p. 1, doi. 10.1186/s40035-023-00383-9
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- Article
Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice.
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- Pharmaceutics, 2023, v. 15, n. 9, p. 2364, doi. 10.3390/pharmaceutics15092364
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- Article
A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis.
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- Science Translational Medicine, 2023, v. 15, n. 708, p. 1, doi. 10.1126/scitranslmed.abn7491
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- Article
TARGETING 2 NEUTRAL SPHINGOMYELINASE 2 PROMOTES DEATH OF HIV-INFECTED CELLS.
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- Topics in Antiviral Medicine, 2023, v. 31, n. 2, p. 175
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- Article
nSMase2 inhibition reduces tau propagation in Alzheimer's Disease mouse models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.063639
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- Publication type:
- Article
EFFECT OF SPRAYING WITH HUMIC ACID AND NANO ZINC ON THE GROWTH AND YIELD OF MATRICARIA CHAMOMILLA L.
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- International Journal of Agricultural & Statistical Sciences, 2022, v. 18, p. 2355
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- Publication type:
- Article
D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/pharmaceutics14102018
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- Article
Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/pharmaceutics14102066
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- Publication type:
- Article
A Novel Oral Glutamate Carboxypeptidase II Inhibitor for the Treatment of Inflammatory Bowel Disease.
- Published in:
- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R3089
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- Publication type:
- Article
Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis.
- Published in:
- Nanotheranostics, 2022, v. 6, n. 2, p. 126, doi. 10.7150/ntno.63158
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- Publication type:
- Article
Comprehensive Metabolic Profiling of MYC-Amplified Medulloblastoma Tumors Reveals Key Dependencies on Amino Acid, Tricarboxylic Acid and Hexosamine Pathways.
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- Cancers, 2022, v. 14, n. 5, p. 1311, doi. 10.3390/cancers14051311
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- Article
The neutral sphingomyelinase 2 inhibitor PDDC reduces tau burden in Alzheimer's disease mice.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054502
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- Publication type:
- Article
Correction to: Glutamine Antagonist JHU083 Normalizes Aberrant Glutamate Production and Cognitive Deficits in the EcoHIV Murine Model of HIV-Associated Neurocognitive Disorders.
- Published in:
- 2021
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- Correction Notice
Elevated body fat increases amphetamine accumulation in brain: evidence from genetic and diet-induced forms of adiposity.
- Published in:
- Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01547-9
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- Article
Glutamine metabolism via glutaminase 1 in autosomal-dominant polycystic kidney disease.
- Published in:
- Nephrology Dialysis Transplantation, 2020, v. 35, n. 10, p. 1824, doi. 10.1093/ndt/gfz109
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- Article
A role for mast cells in geographic atrophy.
- Published in:
- FASEB Journal, 2020, v. 34, n. 8, p. 10117, doi. 10.1096/fj.202000807R
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- Article
DCC-related developmental effects of abused- versus therapeutic-like amphetamine doses in adolescence.
- Published in:
- 2020
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- Publication type:
- journal article
Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells.
- Published in:
- 2020
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- Publication type:
- journal article
Looking for Drugs in All the Wrong Places: Use of GCPII Inhibitors Outside the Brain.
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- Neurochemical Research, 2020, v. 45, n. 6, p. 1256, doi. 10.1007/s11064-019-02909-y
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- Publication type:
- Article
A novel and potent brain penetrant inhibitor of extracellular vesicle release.
- Published in:
- 2019
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- Publication type:
- journal article
Glutamine Antagonist JHU083 Normalizes Aberrant Glutamate Production and Cognitive Deficits in the EcoHIV Murine Model of HIV-Associated Neurocognitive Disorders.
- Published in:
- Journal of NeuroImmune Pharmacology, 2019, v. 14, n. 3, p. 391, doi. 10.1007/s11481-019-09859-w
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- Publication type:
- Article
ATRT-04. UNBIASED METABOLIC PROFILING OF ATYPICAL TERATOID/RHABDOID TUMORS PREDICTS SENSITIVITY TO GLUTAMINE METABOLIC INHIBITORS.
- Published in:
- Neuro-Oncology, 2019, v. 21, p. ii63, doi. 10.1093/neuonc/noz036.003
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- Publication type:
- Article
DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-36144-2
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- Publication type:
- Article
Glutamine metabolism via glutaminase 1 in autosomal-dominant polycystic kidney disease.
- Published in:
- Nephrology Dialysis Transplantation, 2018, v. 33, n. 8, p. 1343, doi. 10.1093/ndt/gfx349
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- Publication type:
- Article
Key Pharmacokinetic Essentials of Fixed-Dosed Combination Products: Case Studies and Perspectives.
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- 2018
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- Publication type:
- journal article
A review of bioanalytical quantitative methods for selected sphingosine 1-phosphate receptor modulators.
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- Biomedical Chromatography, 2018, v. 32, n. 1, p. n/a, doi. 10.1002/bmc.4109
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- Publication type:
- Article
Oral administration of D-alanine in monkeys robustly increases plasma and cerebrospinal fluid levels but experimental D-amino acid oxidase inhibitors had minimal effect.
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- 2016
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- Publication type:
- journal article
Property-Guided Synthesis of Aza-Tricyclic Indolines: Development of Gold Catalysis En Route.
- Published in:
- Advanced Synthesis & Catalysis, 2016, v. 358, n. 9, p. 1482, doi. 10.1002/adsc.201501101
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- Publication type:
- Article
Selective CNS Uptake of the GCP-II Inhibitor 2-PMPA following Intranasal Administration.
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- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131861
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- Publication type:
- Article
Gastrointestinal delivery of propofol from fospropofol: its bioavailability and activity in rodents and human volunteers.
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- Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0526-9
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- Publication type:
- Article
Regional brain distribution of translocator protein using [C]DPA-713 PET in individuals infected with HIV.
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- Journal of NeuroVirology, 2014, v. 20, n. 3, p. 219, doi. 10.1007/s13365-014-0239-5
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- Publication type:
- Article
Quantitation of unbound sunitinib and its metabolite N-desethyl sunitinib (SU12662) in human plasma by equilibrium dialysis and liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.
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- Biomedical Chromatography, 2012, v. 26, n. 11, p. 1315, doi. 10.1002/bmc.2697
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- Article
Method to Screen Substrates of Apical Sodium-Dependent Bile Acid Transporter.
- Published in:
- AAPS Journal, 2008, v. 10, n. 4, p. 596, doi. 10.1208/s12248-008-9069-9
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- Publication type:
- Article