Works by Rahim, Ahad A

Results: 36

New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy.

Published in:

European Journal of Pediatrics, 2022, v. 181, n. 3, p. 875, doi. 10.1007/s00431-021-04320-8

By:

Victor, Suresh;
Rocha-Ferreira, Eridan;
Rahim, Ahad;
Hagberg, Henrik;
Edwards, David

Publication type:

Article

Fetal gene therapy.

Published in:

Journal of Inherited Metabolic Disease, 2024, v. 47, n. 1, p. 192, doi. 10.1002/jimd.12659

By:

Waddington, Simon N.;
Peranteau, William H.;
Rahim, Ahad A.;
Boyle, Ashley K.;
Kurian, Manju A.;
Gissen, Paul;
Chan, Jerry K. Y.;
David, Anna L.

Publication type:

Article

Erratum to: Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes.

Published in:

2013

By:

Burke, Derek;
Rahim, Ahad;
Waddington, Simon;
Karlsson, Stefan;
Enquist, Ida;
Bhatia, Kailash;
Mehta, Atul;
Vellodi, Ashok;
Heales, Simon

Publication type:

Correction Notice

Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes.

Published in:

Journal of Inherited Metabolic Disease, 2013, v. 36, n. 5, p. 869, doi. 10.1007/s10545-012-9561-3

By:

Burke, Derek;
Rahim, Ahad;
Waddington, Simon;
Karlsson, Stefan;
Enquist, Ida;
Bhatia, Kailash;
Mehta, Atul;
Vellodi, Ashok;
Heales, Simon

Publication type:

Article

Targeted retroviral gene delivery using ultrasound.

Published in:

Journal of Gene Medicine, 2007, v. 9, n. 2, p. 77, doi. 10.1002/jgm.1003

By:

Taylor, Sarah L.;
Rahim, Ahad A.;
Bush, Nigel L.;
Bamber, Jeffrey C.;
Porter, Colin D.

Publication type:

Article

Spatial and acoustic pressure dependence of microbubble-mediated gene delivery targeted using focused ultrasound.

Published in:

Journal of Gene Medicine, 2006, v. 8, n. 11, p. 1347, doi. 10.1002/jgm.962

By:

Rahim, Ahad A.;
Taylor, Sarah L.;
Bush, Nigel L.;
ter Haar, Gail R.;
Bamber, Jeffrey C.;
Porter, Colin D.

Publication type:

Article

Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05972-1

By:

Baruteau, Julien;
Perocheau, Dany P.;
Hanley, Joanna;
Lorvellec, Maëlle;
Rocha-Ferreira, Eridan;
Karda, Rajvinder;
Ng, Joanne;
Suff, Natalie;
Diaz, Juan Antinao;
Rahim, Ahad A.;
Hughes, Michael P.;
Banushi, Blerida;
Prunty, Helen;
Hristova, Mariya;
Ridout, Deborah A.;
Virasami, Alex;
Heales, Simon;
Howe, Stewen J.;
Buckley, Suzanne M. K.;
Mills, Philippa B.

Publication type:

Article

Perinatal systemic gene delivery using adeno-associated viral vectors.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00089

By:

Karda, Rajvinder;
Buckley, Suzanne M. K.;
Mattar, Citra N.;
Ng, Joanne;
Massaro, Giulia;
Hughes, Michael P.;
Kurian, Manju A.;
Baruteau, Julien;
Gissen, Paul;
Chan, Jerry K. Y.;
Bacchelli, Chiara;
Waddington, Simon N.;
Rahim, Ahad A.

Publication type:

Article

Delineating pathological pathways in a chemically induced mouse model of Gaucher disease.

Published in:

Journal of Pathology, 2016, v. 239, n. 4, p. 496, doi. 10.1002/path.4751

By:

Vardi, Ayelet;
Zigdon, Hila;
Meshcheriakova, Anna;
Klein, Andrés D;
Yaacobi, Chen;
Eilam, Raya;
Kenwood, Brandon M;
Rahim, Ahad A;
Massaro, Giulia;
Merrill, Alfred H;
Vitner, Einat B;
Futerman, Anthony H

Publication type:

Article

Intravenous administration of AAV2/9 to the fetal and neonatal mouse leads to differential targeting of CNS cell types and extensive transduction of the nervous system.

Published in:

FASEB Journal, 2011, v. 25, n. 10, p. 3505, doi. 10.1096/fj.11-182311

By:

Rahim, Ahad A.;
Wong, Andrew M. S.;
Hoefer, Klemens;
Buckley, Suzanne M. K.;
Mattar, Citra N.;
Cheng, Seng H.;
Chan, Jerry K. Y.;
Cooper, Jonathan D.;
Waddington, Simon N.

Publication type:

Article

Nuclear Localisation Sequence Templated Nonviral Gene Delivery Vectors: Investigation of Intracellular Trafficking Events of LMD and LD Vector Systems ( LMD=liposome:mu peptide:DNA; LD=liposome:plasmid DNA).

Published in:

ChemBioChem, 2003, v. 4, n. 4, p. 286, doi. 10.1002/cbic.200390049

By:

Michael Keller;
Richard P. Harbottle;
Eric Perouzel;
Morvane Colin;
Imran Shah;
Ahad Rahim;
Laurence Vaysse;
Anna Bergau;
Sylviane Moritz;
Christiane Brahimi-Horn;
Charles Coutelle;
Andrew D. Miller

Publication type:

Article

Comparison of different promoters to improve AAV vector-mediated gene therapy for neuronopathic Gaucher disease.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 17, p. 1467, doi. 10.1093/hmg/ddae081

By:

Massaro, Giulia;
Geard, Amy F;
Nelvagal, Hemanth R;
Gore, Katrina;
Clemo, Nadine K;
Waddington, Simon N;
Rahim, Ahad A

Publication type:

Article

Systemic AAV9 gene therapy using the synapsin I promoter rescues a mouse model of neuronopathic Gaucher disease but with limited cross-correction potential to astrocytes.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 12, p. 1933, doi. 10.1093/hmg/ddz317

By:

Massaro, Giulia;
Hughes, Michael P;
Whaler, Sammie M;
Wallom, Kerri-Lee;
Priestman, David A;
Platt, Frances M;
Waddington, Simon N;
Rahim, Ahad A

Publication type:

Article

Neonatal brain-directed gene therapy rescues a mouse model of neurodegenerative CLN6 Batten disease.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 23, p. 3867, doi. 10.1093/hmg/ddz210

By:

Holthaus, Sophia-Martha kleine;
Herranz-Martin, Saul;
Massaro, Giulia;
Aristorena, Mikel;
Hoke, Justin;
Hughes, Michael P.;
Maswood, Ryea;
Semenyuk, Olha;
Basche, Mark;
Shah, Amna Z.;
Klaska, Izabela P.;
Smith, Alexander J.;
Mole, Sara E.;
Rahim, Ahad A.;
Ali, Robin R.

Publication type:

Article

Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy.

Published in:

2018

By:

Rocha-Ferreira, Eridan;
Poupon, Laura;
Zelco, Aura;
Leverin, Anna-Lena;
Nair, Syam;
Jonsdotter, Andrea;
Carlsson, Ylva;
Thornton, Claire;
Hagberg, Henrik;
Rahim, Ahad A

Publication type:

journal article

Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59075-3

By:

Karda, Rajvinder;
Rahim, Ahad A.;
Wong, Andrew M. S.;
Suff, Natalie;
Diaz, Juan Antinao;
Perocheau, Dany P.;
Tijani, Maha;
Ng, Joanne;
Baruteau, Julien;
Martin, Nuria Palomar;
Hughes, Michael;
Delhove, Juliette M. K. M.;
Counsell, John R.;
Cooper, Jonathan D.;
Henckaerts, Els;
Mckay, Tristan R.;
Buckley, Suzanne M. K.;
Waddington, Simon N.

Publication type:

Article

Epilepsy Gene Therapy Using an Engineered Potassium Channel.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 16, p. 3159, doi. 10.1523/JNEUROSCI.1143-18.2019

By:

Snowball, Albert;
Chabrol, Elodie;
Wykes, Robert C.;
Shekh-Ahmad, Tawfeeq;
Cornford, Jonathan H.;
Lieb, Andreas;
Hughes, Michael P.;
Massaro, Giulia;
Rahim, Ahad A.;
Hashemi, Kevan S.;
Kullmann, Dimitri M.;
Walker, Matthew C.;
Schorge, Stephanie

Publication type:

Article

Clinical and Molecular Features of Early Infantile Niemann Pick Type C Disease.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 14, p. 5059, doi. 10.3390/ijms21145059

By:

Seker Yilmaz, Berna;
Baruteau, Julien;
Rahim, Ahad A.;
Gissen, Paul

Publication type:

Article

Inhibition of Mitochondrial Complex I Impairs Release of α-Galactosidase by Jurkat Cells.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 18, p. 4349, doi. 10.3390/ijms20184349

By:

Lambert, Jonathan R. A.;
Howe, Steven J.;
Rahim, Ahad A.;
Burke, Derek G.;
Heales, Simon J. R.

Publication type:

Article

In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters.

Published in:

Scientific Reports, 2015, p. 11842, doi. 10.1038/srep11842

By:

Buckley, Suzanne M. K.;
Delhove, Juliette M. K. M.;
Perocheau, Dany P.;
Karda, Rajvinder;
Rahim, Ahad A.;
Howe, Steven J.;
Ward, Natalie J.;
Birrell, Mark A.;
Belvisi, Maria G.;
Arbuthnot, Patrick;
Johnson, Mark R.;
Waddington, Simon N.;
McKay, Tristan R.

Publication type:

Article

Diabetes drugs activate neuroprotective pathways in models of neonatal hypoxic-ischemic encephalopathy.

Published in:

EMBO Molecular Medicine, 2024, v. 16, n. 6, p. 1284, doi. 10.1038/s44321-024-00079-1

By:

Poupon-Bejuit, Laura;
Geard, Amy;
Millicheap, Nathan;
Rocha-Ferreira, Eridan;
Hagberg, Henrik;
Thornton, Claire;
Rahim, Ahad A

Publication type:

Article

Evidence for Contribution of CD4+CD25+ Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery.

Published in:

Journal of Immunology Research, 2015, v. 2015, p. 1, doi. 10.1155/2015/397879

By:

Nivsarkar, Megha S.;
Buckley, Suzanne M. K.;
Parker, Alan L.;
Perocheau, Dany;
McKay, Tristan R.;
Rahim, Ahad A.;
Howe, Steven J.;
Waddington, Simon N.

Publication type:

Article

Evidence for contribution of CD4+ CD25+ regulatory T cells in maintaining immune tolerance to human factor IX following perinatal adenovirus vector delivery.

Published in:

2015

By:

Nivsarkar, Megha S;
Buckley, Suzanne M K;
Parker, Alan L;
Perocheau, Dany;
McKay, Tristan R;
Rahim, Ahad A;
Howe, Steven J;
Waddington, Simon N

Publication type:

journal article

A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann–Pick Type C1 Disease.

Published in:

Cells (2073-4409), 2023, v. 12, n. 12, p. 1619, doi. 10.3390/cells12121619

By:

Hughes, Michael Paul;
Nelvagal, Hemanth Ramesh;
Coombe-Tennant, Oliver;
Smith, Dave;
Smith, Claire;
Massaro, Giulia;
Poupon-Bejuit, Laura;
Platt, Frances Mary;
Rahim, Ahad Abdul

Publication type:

Article

Gene therapy for global brain diseases: one small step for mice, one giant leap for humans.

Published in:

2020

By:

Rahim, Ahad A;
Gissen, Paul

Publication type:

journal article

Influence of Coagulation Factor X on In Vitro and In Vivo Gene Delivery by Adenovirus (Ad) 5, Ad35, and Chimeric Ad5/Ad35 Vectors.

Published in:

Molecular Therapy, 2009, v. 17, n. 10, p. 1683, doi. 10.1038/mt.2009.152

By:

Greig, Jenny A.;
Buckley, Suzanne M. K.;
Waddington, Simon N.;
Parker, Alan L.;
Bhella, David;
Pink, Rebecca;
Rahim, Ahad A.;
Morita, Takashi;
Nicklin, Stuart A.;
McVey, John H.;
Baker, Andrew H.

Publication type:

Article

546. Targeted Non-Viral Gene Delivery Using Microbubbles and Focused Ultrasound.

Published in:

Molecular Therapy, 2006, v. 13, p. S210, doi. 10.1016/j.ymthe.2006.08.618

By:

Rahim, Ahad;
Taylor, Sarah L.;
Bush, Nigel L.;
ter Haar, Gail R.;
Bamber, Jeff C.;
Porter, Colin D.

Publication type:

Article

Corrigendum to “Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice”.

Published in:

Molecular Therapy, 2006, v. 13, n. 4, p. 830, doi. 10.1016/j.ymthe.2005.10.003

By:

Themis, Mike;
Waddington, Simon N.;
Schmidt, Manfred;
von Kalle, Christof;
Wang, Yoahe;
Al-Allaf, Faisal;
Gregory, Lisa G.;
Nivsarkar, Megha;
Themis, Matthew;
Holder, Maxine V.;
Buckley, Suzanne M.K.;
Dighe, Niraja;
Ruthe, Alaine T.;
Mistry, Ajay;
Bigger, Brian;
Rahim, Ahad;
Nguyen, Tuan H.;
Trono, Didier;
Thrasher, Adrian J.;
Coutelle, Charles

Publication type:

Article

Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice

Published in:

Molecular Therapy, 2005, v. 12, n. 4, p. 763, doi. 10.1016/j.ymthe.2005.07.358

By:

Themis, Mike;
Waddington, Simon N.;
Schmidt, Manfred;
von Kalle, Christof;
Wang, Yoahe;
Al-Allaf, Faisal;
Gregory, Lisa G.;
Nivsarkar, Megha;
Themis, Matthew;
Holder, Maxine V.;
Buckley, Suzanne M.K.;
Dighe, Niraja;
Ruthe, Alaine T.;
Mistry, Ajay;
Bigger, Brian;
Rahim, Ahad;
Nguyen, Tuan H.;
Trono, Didier;
Thrasher, Adrian J.;
Coutelle, Charles

Publication type:

Article

484. Ultrasound-Mediated Microbubble Destruction and Retroviral Gene Delivery

Published in:

2005

By:

Taylor, Sarah L.;
Rahim, Ahad;
Bush, Nigel;
Bamber, Jeff;
Porter, Colin

Publication type:

Abstract

209. Nuclear Localization Mediated by the Adenoviral-Core Peptide Mu Enhances Phage φC31-Integrase Activity in Mammalian Cells

Published in:

2005

By:

Harbottle, Richard P.;
Vaysse, Laurence;
Rahim, Ahad;
Kienast, Yvonne;
Passa, Ourania;
Tolmachov, Oleg;
Coutelle, Charles

Publication type:

Abstract

Gene Therapy for Lysosomal Storage Disorders: Ongoing Studies and Clinical Development.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 4, p. 611, doi. 10.3390/biom11040611

By:

Massaro, Giulia;
Geard, Amy F.;
Liu, Wenfei;
Coombe-Tennant, Oliver;
Waddington, Simon N.;
Baruteau, Julien;
Gissen, Paul;
Rahim, Ahad A.

Publication type:

Article

Immediate Remote Ischemic Postconditioning Reduces Brain Nitrotyrosine Formation in a Piglet Asphyxia Model.

Published in:

Oxidative Medicine & Cellular Longevity, 2016, p. 1, doi. 10.1155/2016/5763743

By:

Rocha-Ferreira, Eridan;
Rudge, Brogan;
Hughes, Michael P.;
Rahim, Ahad A.;
Hristova, Mariya;
Robertson, Nicola J.

Publication type:

Article

Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair.

Published in:

Stem Cells International, 2016, p. 1, doi. 10.1155/2016/7502178

By:

Bhangra, Kulraj Singh;
Busuttil, Francesca;
Phillips, James B.;
Rahim, Ahad A.

Publication type:

Article

Neuroprotective Effects of Diabetes Drugs for the Treatment of Neonatal Hypoxia-Ischemia Encephalopathy.

Published in:

Frontiers in Cellular Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fncel.2020.00112

By:

Poupon-Bejuit, Laura;
Rocha-Ferreira, Eridan;
Thornton, Claire;
Hagberg, Henrik;
Rahim, Ahad A.

Publication type:

Article

Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates.

Published in:

FASEB Journal, 2015, v. 29, n. 9, p. 3876, doi. 10.1096/fj.14-269092

By:

Mattar, Citra N.;
Wong, Andrew M. S.;
Hoefer, Klemens;
Alonso-Ferrero, Maria E.;
Buckley, Suzanne M. K.;
Howe, Steven J.;
Cooper, Jonathan D.;
Waddington, Simon N.;
Chan, Jerry K. Y.;
Rahim, Ahad A.

Publication type:

Article