Works by Rafacho, Alex

Results: 31

Intranasal pramlintide matches intraperitoneal effects on food intake and gastric emptying in mice.

Published in:

Endocrine (1355008X), 2025, v. 89, n. 1, p. 79, doi. 10.1007/s12020-025-04220-z

By:

Almeida, Milena S.;
Sanches, Mariele P.;
Tonet, Natália S.;
Zuglianello, Carine;
Morari, Joseane;
Velloso, Licio A.;
Lemos-Senna, Elenara;
Rafacho, Alex

Publication type:

Article

Prevention of Elevation in Plasma Triacylglycerol with High-Dose Bezafibrate Treatment Abolishes Insulin Resistance and Attenuates Glucose Intolerance Induced by Short-Term Treatment with Dexamethasone in Rats.

Published in:

International Journal of Endocrinology, 2018, p. 1, doi. 10.1155/2018/3257812

By:

Inácio, Maiara Destro;
Rafacho, Alex;
de Paula Camaforte, Nathália Aparecida;
Teixeira, Poliana;
Vareda, Priscilla Maria Ponce;
Violato, Natália Moretti;
Bosqueiro, José Roberto

Publication type:

Article

Excess of glucocorticoids during late gestation impairs the recovery of offspring’s β‐cell function after a postnatal injury.

Published in:

FASEB Journal, 2021, v. 35, n. 8, p. 1, doi. 10.1096/fj.202100841R

By:

dos Santos, Cristiane;
Rafacho, Alex;
Ferreira, Sandra Mara;
Vettorazzi, Jean Franciesco;
dos Reis Araújo, Thiago;
Mateus Gonçalves, Luciana;
Ruhrmann, Sabrina;
Bacos, Karl;
Ling, Charlotte;
Boschero, Antônio Carlos;
Jorge dos Santos, Gustavo

Publication type:

Article

Enriched environment ameliorates dexamethasone effects on emotional reactivity and metabolic parameters in mice.

Published in:

2020

By:

Delanogare, Eslen;
de Souza, Raul Marin;
Rosa, Giovana Karoline;
Guanabara, Fernando Garcia;
Rafacho, Alex;
Moreira, Eduardo Luiz Gasnhar

Publication type:

Report

Augmented β-Cell Function and Mass in Glucocorticoid-Treated Rodents Are Associated with Increased Islet Ir-β/AKT/mTOR and Decreased AMPK/ACC and AS160 Signaling.

Published in:

International Journal of Endocrinology, 2014, p. 1, doi. 10.1155/2014/983453

By:

Protzek, André O. P.;
Costa-Júnior, José M.;
Rezende, Luiz F.;
Santos, Gustavo J.;
Araújo, Tiago Gomes;
Vettorazzi, Jean F.;
Ortis, Fernanda;
Carneiro, Everardo M.;
Rafacho, Alex;
Boschero, Antonio C.

Publication type:

Article

Pep19 Has a Positive Effect on Insulin Sensitivity and Ameliorates Both Hepatic and Adipose Tissue Phenotype of Diet-Induced Obese Mice.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 8, p. 4082, doi. 10.3390/ijms23084082

By:

Silvério, Renata;
Barth, Robson;
Heimann, Andrea S.;
Reckziegel, Patrícia;
dos Santos, Gustavo J.;
Romero-Zerbo, Silvana Y.;
Bermúdez-Silva, Francisco J.;
Rafacho, Alex;
Ferro, Emer S.

Publication type:

Article

Liraglutide counteracts obesity and glucose intolerance in a mouse model of glucocorticoidinduced metabolic syndrome.

Published in:

Diabetology & Metabolic Syndrome, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-5996-6-3

By:

Fransson, Liselotte;
dos Santos, Cristiane;
Wolbert, Petra;
Sjöholm, Åke;
Rafacho, Alex;
Ortsäter, Henrik

Publication type:

Article

Glucose homeostasis in two degrees of sepsis lethality induced by caecum ligation and puncture in mice.

Published in:

International Journal of Experimental Pathology, 2017, v. 98, n. 6, p. 329, doi. 10.1111/iep.12255

By:

Ferreira, Francielle B. D.;
dos Santos, Cristiane;
Bruxel, Maciel A.;
Nunes, Everson A.;
Spiller, Fernando;
Rafacho, Alex

Publication type:

Article

Prostate hyperplasia caused by long-term obesity is characterized by high deposition of extracellular matrix and increased content of MMP-9 and VEGF.

Published in:

International Journal of Experimental Pathology, 2015, v. 96, n. 1, p. 21, doi. 10.1111/iep.12107

By:

Silva, Silas Amâncio;
Gobbo, Marina Guimarães;
Pinto‐Fochi, Maria Etelvina;
Rafacho, Alex;
Taboga, Sebastião Roberto;
Almeida, Eduardo Alves;
Góes, Rejane Maira;
Ribeiro, Daniele Lisboa

Publication type:

Article

Long-term dexamethasone treatment alters the histomorphology of acinar cells in rat parotid and submandibular glands.

Published in:

International Journal of Experimental Pathology, 2014, v. 95, n. 5, p. 351, doi. 10.1111/iep.12092

By:

Bighetti, Bruna B.;
Assis, Gerson F. d.;
Vieira, Danilo C.;
Violato, Natalia M.;
Cestari, Tania M.;
Taga, Rumio;
Bosqueiro, José R.;
Rafacho, Alex

Publication type:

Article

Increased pancreatic islet mass is accompanied by activation of the insulin receptor substrate-2/serine-threonine kinase pathway and augmented cyclin D<sub>2</sub> protein levels in insulin-resistant rats.

Published in:

International Journal of Experimental Pathology, 2008, v. 89, n. 4, p. 264, doi. 10.1111/j.1365-2613.2008.00588.x

By:

Rafacho, Alex;
Ribeiro, Daniele Lisboa;
Boschero, Antonio Carlos;
Taboga, Sebastião Roberto;
Bosqueiro, José Roberto

Publication type:

Article

Hyperglucagonemia and glucagon hypersecretion in early type 2 diabetes result from multifaceted dysregulation of pancreatic mouse α-cells.

Published in:

Pflügers Archiv: European Journal of Physiology, 2025, v. 477, n. 2, p. 207, doi. 10.1007/s00424-024-03045-5

By:

Ruiz-Pino, Antonia;
Goncalves-Ramírez, Arianna;
Jiménez-Palomares, Margarita;
Merino, Beatriz;
Castellano-Muñoz, Manuel;
Vettorazzi, Jean F.;
Rafacho, Alex;
Marroquí, Laura;
Nadal, Ángel;
Alonso-Magdalena, Paloma;
Perdomo, Germán;
Cózar-Castellano, Irene;
Quesada, Ivan

Publication type:

Article

Structural Concepts, Definition, Classification, and Macronutrient and Food Composition of Carbohydrate-Restricted Diets for Individuals with Type 2 Diabetes Mellitus: A Scoping Review.

Published in:

Nutrients, 2025, v. 17, n. 6, p. 1061, doi. 10.3390/nu17061061

By:

Medeiros, Fharlley Lohann;
Fernandes, Ana Carolina;
Kraemer, Mariana V. S.;
Padovan, Marina;
Bernardo, Greyce Luci;
Uggioni, Paula Lazzarin;
Rafacho, Alex;
Proença, Rossana P. C.

Publication type:

Article

Age- and gender-related changes in glucose homeostasis in glucocorticoid-treated rats.

Published in:

Canadian Journal of Physiology & Pharmacology, 2014, v. 92, n. 10, p. 867, doi. 10.1139/cjpp-2014-0259

By:

dos Santos, Cristiane;
Ferreira, Francielle Batista D.;
Gonçalves-Neto, Luiz M.;
Taboga, Sebastião Roberto;
Boschero, Antonio Carlos;
Rafacho, Alex

Publication type:

Article

Impact of Fish Oil Supplementation and Interruption of Fructose Ingestion on Glucose and Lipid Homeostasis of Rats Drinking Different Concentrations of Fructose.

Published in:

BioMed Research International, 2017, v. 2017, p. 1, doi. 10.1155/2017/4378328

By:

Sulis, Paola M.;
Motta, Katia;
Barbosa, Amanda M.;
Besen, Matheus H.;
da Silva, Julia S.;
Nunes, Everson A.;
Rafacho, Alex

Publication type:

Article

Twenty-four weeks of combined training in different environments, aquatic and land, in the type 2 diabetes management (Aquatic and Land Exercise for Diabetes -ALED): protocol of a randomized clinical trial.

Published in:

Trials, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s13063-024-08660-2

By:

dos Santos Leonel, Larissa;
Wolin, Ingrid Alessandra Victoria;
Danielevicz, Angélica;
Diesel, Mabel;
Constantini, Marina Isolde;
de Oliveira Junior, João Batista;
Souza, Allana Andrade;
Reichert, Thaís;
Silveira-Rodrigues, João Gabriel;
Soares, Danusa Dias;
Ronsoni, Marcelo Fernando;
Van De Sande Lee, Simone;
Rafacho, Alex;
Speretta, Guilherme Fleury Fina;
Lottermann, Karla Siqueira;
Bertoli, Josefina;
Muller, Alexandre Pastoris;
Gerage, Aline Mendes;
de La Rocha Freitas, Cíntia;
Delevatti, Rodrigo Sudatti

Publication type:

Article

Tissue integrity, costs and time associated with different agents for histological bone preparation.

Published in:

Microscopy Research & Technique, 2017, v. 80, n. 4, p. 344, doi. 10.1002/jemt.22798

By:

Abrantes, Adelino António Artur;
Rafacho, Alex;
Rivero, Elena Riet Correa;
Mariano, Fernanda Viviane;
Siqueira, Filipe Modolo;
Gondak, Rogério Oliveira

Publication type:

Article

Reduced glucose-induced insulin secretion in low-protein-fed rats is associated with altered pancreatic islets redox status.

Published in:

Journal of Cellular Physiology, 2018, v. 233, n. 1, p. 486, doi. 10.1002/jcp.25908

By:

Cappelli, Ana Paula G.;
Zoppi, Claudio C.;
Silveira, Leonardo R.;
Batista, Thiago M.;
Paula, Flávia M.;
da Silva, Priscilla M. R.;
Rafacho, Alex;
Barbosa-Sampaio, Helena C.;
Boschero, Antonio C.;
Carneiro, Everardo M.

Publication type:

Article

Effects of glucocorticoids and exercise on pancreatic [beta]-cell function and diabetes development: comments on Beaudry and Riddel.

Published in:

2014

By:

Rafacho, Alex

Publication type:

Journal Article

Effects of glucocorticoids and exercise on pancreatic β-cell function and diabetes development: comments on Beaudry and Riddel.

Published in:

Diabetes/Metabolism Research & Reviews, 2014, v. 30, n. 2, p. 120, doi. 10.1002/dmrr.2473

By:

Rafacho, Alex

Publication type:

Article

The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease.

Published in:

Frontiers in Endocrinology, 2020, p. 1, doi. 10.3389/fendo.2020.00103

By:

Romero-Zerbo, Silvana Y.;
García-Fernández, María;
Espinosa-Jiménez, Vanesa;
Pozo-Morales, Macarena;
Escamilla-Sánchez, Alejandro;
Sánchez-Salido, Lourdes;
Lara, Estrella;
Cobo-Vuilleumier, Nadia;
Rafacho, Alex;
Olveira, Gabriel;
Rojo-Martínez, Gemma;
Gauthier, Benoit R.;
González-Mariscal, Isabel;
Bermúdez-Silva, Francisco J.

Publication type:

Article

Pancreatic Alpha-Cell Dysfunction Contributes to the Disruption of Glucose Homeostasis and Compensatory Insulin Hypersecretion in Glucocorticoid-Treated Rats.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0093531

By:

Rafacho, Alex;
Gonçalves-Neto, Luiz M.;
Santos-Silva, Junia C.;
Alonso-Magdalena, Paloma;
Merino, Beatriz;
Taboga, Sebastião R.;
Carneiro, Everardo M.;
Boschero, Antonio C.;
Nadal, Angel;
Quesada, Ivan

Publication type:

Article

Fish oil supplementation attenuates changes in plasma lipids caused by dexamethasone treatment in rats.

Published in:

Applied Physiology, Nutrition & Metabolism, 2016, v. 41, n. 4, p. 382, doi. 10.1139/apnm-2015-0487

By:

Barbosa, Amanda Marreiro;
Francisco, Priscila de Cássia;
Motta, Katia;
Chagas, Thayz Rodrigues;
dos Santos, Cristiane;
Rafacho, Alex;
Nunes, Everson Araújo

Publication type:

Article

Glucose intolerance induced by glucocorticoid excess is further impaired by co-administration with β-hydroxy-β-methylbutyrate in rats.

Published in:

2013

By:

Nunes, Everson A.;
Gonçalves-Neto, Luiz M.;
Ferreira, Francielle B.D.;
dos Santos, Cristiane;
Fernandes, Luiz C.;
Boschero, Antonio C.;
Calder, Philip C.;
Rafacho, Alex

Publication type:

Journal Article

Glucose intolerance induced by glucocorticoid excess is further impaired by co-administration with β-hydroxy-β-methylbutyrate in rats.

Published in:

Applied Physiology, Nutrition & Metabolism, 2013, v. 38, n. 11, p. 1137, doi. 10.1139/apnm-2012-0456

By:

Nunes, Everson A.;
Gonçalves-Neto, Luiz M.;
Ferreira, Francielle B.D.;
dos Santos, Cristiane;
Fernandes, Luiz C.;
Boschero, Antonio C.;
Calder, Philip C.;
Rafacho, Alex

Publication type:

Article

Chronic Metabolic Derangement-Induced Cognitive Deficits and Neurotoxicity Are Associated with REST Inactivation.

Published in:

Molecular Neurobiology, 2019, v. 56, n. 3, p. 1539, doi. 10.1007/s12035-018-1175-9

By:

Remor, Aline Pertile;
da Silva, Rodrigo Augusto;
de Matos, Filipe José;
Glaser, Viviane;
de Paula Martins, Roberta;
Ghisoni, Karina;
da Luz Scheffer, Débora;
Andia, Denise Carleto;
Portinho, Daniele;
de Souza, Ana Paula;
de Oliveira, Paulo Alexandre;
Prediger, Rui Daniel;
Torres, Alicia I.;
Linhares, Rose Marie Mueller;
Walz, Roger;
Ronsoni, Marcelo Fernando;
Hohl, Alexandre;
Rafacho, Alex;
Aguiar, Aderbal Silva;
De Paul, Ana Lucia

Publication type:

Article

Exercise training prevents hyperinsulinemia, muscular glycogen loss and muscle atrophy induced by dexamethasone treatment.

Published in:

2010

By:

Barel, Matheus;
Perez, Otávio André Brogin;
Giozzet, Vanessa Aparecida;
Rafacho, Alex;
Bosqueiro, José Roberto;
Amaral, Sandra;
Perez, Otávio André Brogin;
Bosqueiro, José Roberto;
do Amaral, Sandra Lia

Publication type:

journal article

Decrement in resting and insulin‐stimulated soleus muscle mitochondrial respiration is an early event in diet‐induced obesity in mice.

Published in:

Experimental Physiology, 2019, v. 104, n. 3, p. 306, doi. 10.1113/EP087317

By:

Brunetta, Henver Simionato;
Paula, Gabriela Cristina;
Oliveira, Jade;
Martins, Eduarda Lopes;
dos Santos, Gustavo Jorge;
Galina, Antonio;
Rafacho, Alex;
Bem, Andreza Fabro;
Nunes, Everson Araújo

Publication type:

Article

The Effects of Aging on Male Mouse Pancreatic β-Cell Function Involve Multiple Events in the Regulation of Secretion: Influence of Insulin Sensitivity.

Published in:

2022

By:

Tudurí, Eva;
Soriano, Sergi;
Almagro, Lucía;
García-Heredia, Anabel;
Rafacho, Alex;
Alonso-Magdalena, Paloma;
Nadal, Ángel;
Quesada, Ivan

Publication type:

journal article

Dexamethasone Administration During Late Gestation Has No Major Impact on Lipid Metabolism, but Reduces Newborn Survival Rate in Wistar Rats.

Published in:

Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.00783

By:

Motta, Katia;
Gomes, Patricia R. L.;
Sulis, Paola M.;
Bordin, Silvana;
Rafacho, Alex

Publication type:

Article

Hepatocyte nuclear factor 4-α is necessary for high fat diet-induced pancreatic β-cell mass expansion and metabolic compensations.

Published in:

Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1511813

By:

de Ramos, Francieli Caroline;
Barth, Robson;
Santos, Marcos Rizzon;
Almeida, Milena dos Santos;
Ferreira, Sandra Mara;
Rafacho, Alex;
Boschero, Antônio Carlos;
Santos, Gustavo Jorge dos

Publication type:

Article