Works by Radulescu, Ovidiu

Results: 32

Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00814-y

By:

Dandou, Sarah;
Amin, Kriti;
D'Hondt, Véronique;
Solassol, Jérôme;
Dereure, Olivier;
Coopman, Peter J.;
Radulescu, Ovidiu;
Fröhlich, Holger;
Larive, Romain M.

Publication type:

Article

MelanoDB: A dataset of clinical and molecular features of patients with advanced melanoma treated with MAPK inhibitors.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05291-3

By:

Dandou, Sarah;
Vendrell, Julie A.;
Solassol, Jérôme;
Louveau, Baptiste;
Lebbé, Céleste;
Mourah, Samia;
Rambow, Florian;
Richard, Eric;
Du Manoir, Stanislas;
Mangé, Alain;
Coopman, Peter J.;
Radulescu, Ovidiu;
Larive, Romain M.

Publication type:

Article

Canalization of Gene Expression in the Drosophila Blastoderm by Gap Gene Cross Regulation.

Published in:

PLoS Biology, 2009, v. 7, n. 3, p. e1000049

By:

Surkova, Svetlana;
Spirov, Alexander V.;
Gursky, Vitaly V.;
Janssens, Hilde;
Kim, Ah-Ram;
Radulescu, Ovidiu;
Vanario-Alonso, Carlos E.;
Sharp 3, David H.;
Samsonova, Maria;
Reinitz, John

Publication type:

Article

Transcriptional Stochasticity as a Key Aspect of HIV-1 Latency.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 9, p. 1969, doi. 10.3390/v15091969

By:

Damour, Alexia;
Slaninova, Vera;
Radulescu, Ovidiu;
Bertrand, Edouard;
Basyuk, Eugenia

Publication type:

Article

The control of transcriptional memory by stable mitotic bookmarking.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28855-y

By:

Bellec, Maëlle;
Dufourt, Jérémy;
Hunt, George;
Lenden-Hasse, Hélène;
Trullo, Antonio;
Zine El Aabidine, Amal;
Lamarque, Marie;
Gaskill, Marissa M.;
Faure-Gautron, Heloïse;
Mannervik, Mattias;
Harrison, Melissa M.;
Andrau, Jean-Christophe;
Favard, Cyril;
Radulescu, Ovidiu;
Lagha, Mounia

Publication type:

Article

Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24462-5

By:

Tantale, Katjana;
Garcia-Oliver, Encar;
Robert, Marie-Cécile;
L'Hostis, Adèle;
Yang, Yueyuxiao;
Tsanov, Nikolay;
Topno, Rachel;
Gostan, Thierry;
Kozulic-Pirher, Alja;
Basu-Shrivastava, Meenakshi;
Mukherjee, Kamalika;
Slaninova, Vera;
Andrau, Jean-Christophe;
Mueller, Florian;
Basyuk, Eugenia;
Radulescu, Ovidiu;
Bertrand, Edouard

Publication type:

Article

Quantitative imaging of transcription in living Drosophila embryos reveals the impact of core promoter motifs on promoter state dynamics.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24461-6

By:

Pimmett, Virginia L.;
Dejean, Matthieu;
Fernandez, Carola;
Trullo, Antonio;
Bertrand, Edouard;
Radulescu, Ovidiu;
Lagha, Mounia

Publication type:

Article

Mathematical basis and toolchain for hierarchical optimization of biochemical networks.

Published in:

PLoS Computational Biology, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pcbi.1012624

By:

Viswan, Nisha Ann;
Tribut, Alexandre;
Gasparyan, Manvel;
Radulescu, Ovidiu;
Bhalla, Upinder S.

Publication type:

Article

Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells.

Published in:

PLoS Computational Biology, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.pcbi.1005432

By:

Naldi, Aurélien;
Larive, Romain M.;
Czerwinska, Urszula;
Urbach, Serge;
Montcourrier, Philippe;
Roy, Christian;
Solassol, Jérôme;
Freiss, Gilles;
Coopman, Peter J.;
Radulescu, Ovidiu

Publication type:

Article

Network Reconstruction and Significant Pathway Extraction Using Phosphoproteomic Data from Cancer Cells.

Published in:

Proteomics, 2019, v. 19, n. 21/22, p. N.PAG, doi. 10.1002/pmic.201800450

By:

Buffard, Marion;
Naldi, Aurélien;
Radulescu, Ovidiu;
Coopman, Peter J.;
Larive, Romain M.;
Freiss, Gilles

Publication type:

Article

Identifying Markov Chain Models from Time-to-Event Data: An Algebraic Approach.

Published in:

Bulletin of Mathematical Biology, 2025, v. 87, n. 1, p. 1, doi. 10.1007/s11538-024-01385-y

By:

Radulescu, Ovidiu;
Grigoriev, Dima;
Seiss, Matthias;
Douaihy, Maria;
Lagha, Mounia;
Bertrand, Edouard

Publication type:

Article

Signal Propagation in Sensing and Reciprocating Cellular Systems with Spatial and Structural Heterogeneity.

Published in:

Bulletin of Mathematical Biology, 2018, v. 80, n. 7, p. 1900, doi. 10.1007/s11538-018-0439-x

By:

Hodgkinson, Arran;
Uzé, Gilles;
Radulescu, Ovidiu;
Trucu, Dumitru

Publication type:

Article

Protein Synthesis Driven by Dynamical Stochastic Transcription.

Published in:

Bulletin of Mathematical Biology, 2016, v. 78, n. 1, p. 110, doi. 10.1007/s11538-015-0131-3

By:

Innocentini, Guilherme;
Forger, Michael;
Radulescu, Ovidiu;
Antoneli, Fernando

Publication type:

Article

A Geometric Method for Model Reduction of Biochemical Networks with Polynomial Rate Functions.

Published in:

Bulletin of Mathematical Biology, 2015, v. 77, n. 12, p. 2180, doi. 10.1007/s11538-015-0118-0

By:

Samal, Satya;
Grigoriev, Dima;
Fröhlich, Holger;
Weber, Andreas;
Radulescu, Ovidiu

Publication type:

Article

Multimodality and Flexibility of Stochastic Gene Expression.

Published in:

Bulletin of Mathematical Biology, 2013, v. 75, n. 12, p. 2600, doi. 10.1007/s11538-013-9909-3

By:

Innocentini, Guilherme da Costa Pereira;
Forger, Michael;
Ramos, Alexandre Ferreira;
Radulescu, Ovidiu;
Hornos, José Eduardo Martinho

Publication type:

Article

Linking metabolic network features to phenotypes using sparse group lasso.

Published in:

Bioinformatics, 2017, v. 33, n. 21, p. 3445, doi. 10.1093/bioinformatics/btx427

By:

Samal, Satya Swarup;
Radulescu, Ovidiu;
Weber, Andreas;
Fröhlich, Holger

Publication type:

Article

Kinetic modelling of phospholipid synthesis in Plasmodium knowlesi unravels crucial steps and relative importance of multiple pathways.

Published in:

BMC Systems Biology, 2013, v. 7, n. 1, p. 1, doi. 10.1186/1752-0509-7-123

By:

Sen, Partho;
Vial, Henri J.;
Radulescu, Ovidiu

Publication type:

Article

Localizing potentially active post-transcriptional regulations in the Ewing's sarcoma gene regulatory network.

Published in:

BMC Systems Biology, 2010, v. 4, p. 146, doi. 10.1186/1752-0509-4-146

By:

Baumuratova, Tatiana;
Surdez, Didier;
Delyon, Bernard;
Stoll, Gautier;
Delattre, Olivier;
Radulescu, Ovidiu;
Siegel, Anne

Publication type:

Article

ODEbase: a repository of ODE systems for systems biology.

Published in:

Bioinformatics Advances, 2022, v. 2, n. 1, p. 1, doi. 10.1093/bioadv/vbac027

By:

Lüders, Christoph;
Sturm, Thomas;
Radulescu, Ovidiu

Publication type:

Article

Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 2, p. 308, doi. 10.3390/biom11020308

By:

Buffard, Marion;
Naldi, Aurélien;
Freiss, Gilles;
Deckert, Marcel;
Radulescu, Ovidiu;
Coopman, Peter J.;
Larive, Romain M.

Publication type:

Article

Computational Model of Heterogeneity in Melanoma: Designing Therapies and Predicting Outcomes.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.857572

By:

Hodgkinson, Arran;
Trucu, Dumitru;
Lacroix, Matthieu;
Le Cam, Laurent;
Radulescu, Ovidiu

Publication type:

Article

Far-From-Equilibrium Time Evolution between Two Gamma Distributions.

Published in:

Entropy, 2017, v. 19, n. 10, p. 511, doi. 10.3390/e19100511

By:

Eun-jin Kim;
Tenkès, Lucille-Marie;
Hollerbach, Rainer;
Radulescu, Ovidiu

Publication type:

Article

Inferring the role of transcription factors in regulatory networks.

Published in:

BMC Bioinformatics, 2008, v. 9, p. 1, doi. 10.1186/1471-2105-9-228

By:

Veber, Philippe;
Guziolowski, Carito;
Le Borgne, Michel;
Radulescu, Ovidiu;
Siegel, Anne

Publication type:

Article

Canalization of Gene Expression and Domain Shifts in the Drosophila Blastoderm by Dynamical Attractors.

Published in:

PLoS Computational Biology, 2009, v. 5, n. 3, p. 1, doi. 10.1371/journal.pcbi.1000303

By:

Surkova, Svetlana;
Spirov, Alexander V.;
Gursky, Vitaly V.;
Janssens, Hilde;
Kim, Ah-Ram;
Radulescu, Ovidiu;
Vanario-Alonso, Carlos E.;
Sharp, David H.;
Samsonova, Maria;
Reinitz, John

Publication type:

Article

FLEXIBLE AND ROBUST NETWORKS.

Published in:

Journal of Bioinformatics & Computational Biology, 2012, v. 10, n. 2, p. 1241011-1, doi. 10.1142/S0219720012410119

By:

VAKULENKO, SERGEY A.;
RADULESCU, OVIDIU

Publication type:

Article

BurstDECONV: a signal deconvolution method to uncover mechanisms of transcriptional bursting in live cells.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 16, p. e88, doi. 10.1093/nar/gkad629

By:

Douaihy, Maria;
Topno, Rachel;
Lagha, Mounia;
Bertrand, Edouard;
Radulescu, Ovidiu

Publication type:

Article

La résistance aux inhibiteurs de BRAF: Les leçons de la clinique.

Published in:

Médecine Sciences, 2022, v. 38, n. 6/7, p. 570, doi. 10.1051/medsci/2022083

By:

Dahmani, Cylia;
Corre, Eulalie;
Dandou, Sarah;
Mangé, Alain;
Radulescu, Ovidiu;
Coopman, Peter J.;
Cuq, Pierre;
Larive, Romain M.

Publication type:

Article

Zelda, le maestro du réveil du génome zygotique.

Published in:

Médecine Sciences, 2019, v. 35, n. 11, p. 821, doi. 10.1051/medsci/2019160

By:

Dufourt, Jeremy;
Bellec, Maëlle;
Messina, Olivier;
Trullo, Antonio;
Favard, Cyril;
Radulescu, Ovidiu;
Lagha, Mounia

Publication type:

Article

Centralized Networks to Generate Human Body Motions.

Published in:

Sensors (14248220), 2017, v. 17, n. 12, p. 2907, doi. 10.3390/s17122907

By:

Vakulenko, Sergei;
Radulescu, Ovidiu;
Morozov, Ivan;
Weber, Andres

Publication type:

Article

An in silico analysis of robust but fragile gene regulation links enhancer length to robustness.

Published in:

PLoS Computational Biology, 2019, v. 15, n. 11, p. 1, doi. 10.1371/journal.pcbi.1007497

By:

Barr, Kenneth;
Reinitz, John;
Radulescu, Ovidiu

Publication type:

Article

Publisher Correction: Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08346-3

By:

Dufourt, Jeremy;
Trullo, Antonio;
Hunter, Jennifer;
Fernandez, Carola;
Lazaro, Jorge;
Dejean, Matthieu;
Morales, Lucas;
Nait-Amer, Saida;
Schulz, Katharine N.;
Harrison, Melissa M.;
Favard, Cyril;
Radulescu, Ovidiu;
Lagha, Mounia

Publication type:

Article

Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07613-z

By:

Dufourt, Jeremy;
Trullo, Antonio;
Hunter, Jennifer;
Fernandez, Carola;
Lazaro, Jorge;
Dejean, Matthieu;
Morales, Lucas;
Nait-Amer, Saida;
Schulz, Katharine N.;
Harrison, Melissa M.;
Favard, Cyril;
Radulescu, Ovidiu;
Lagha, Mounia

Publication type:

Article