Works by Radi, Rafael

Results: 47

Structural basis of redox-dependent modulation of galectin-1 dynamics and function.

Published in:

Glycobiology, 2014, v. 24, n. 5, p. 428, doi. 10.1093/glycob/cwu008

By:

Guardia, Carlos M;
Caramelo, Julio J;
Trujillo, Madia;
Méndez-Huergo, Santiago P;
Radi, Rafael;
Estrin, Darío A;
Rabinovich, Gabriel A

Publication type:

Article

Culture of Bovine Aortic Endothelial Cells in Galactose Media Enhances Mitochondrial Plasticity and Changes Redox Sensing, Altering Nrf2 and FOXO3 Levels.

Published in:

Antioxidants, 2024, v. 13, n. 7, p. 873, doi. 10.3390/antiox13070873

By:

Galant, Leticia Selinger;
Doblado, Laura;
Radi, Rafael;
de Bem, Andreza Fabro;
Monsalve, Maria

Publication type:

Article

Mitochondrial Peroxiredoxin 3 Is Rapidly Oxidized and Hyperoxidized by Fatty Acid Hydroperoxides.

Published in:

Antioxidants, 2023, v. 12, n. 2, p. 408, doi. 10.3390/antiox12020408

By:

Cardozo, Giuliana;
Mastrogiovanni, Mauricio;
Zeida, Ari;
Viera, Nicolás;
Radi, Rafael;
Reyes, Aníbal M.;
Trujillo, Madia

Publication type:

Article

Leghemoglobin is nitrated in functional legume nodules in a tyrosine residue within the heme cavity by a nitrite/peroxide-dependent mechanism.

Published in:

Plant Journal, 2015, v. 81, n. 5, p. 723, doi. 10.1111/tpj.12762

By:

Sainz, Martha;
Calvo‐Begueria, Laura;
Pérez‐Rontomé, Carmen;
Wienkoop, Stefanie;
Abián, Joaquín;
Staudinger, Christiana;
Bartesaghi, Silvina;
Radi, Rafael;
Becana, Manuel

Publication type:

Article

Human Mn-superoxide dismutase inactivation by peroxynitrite: a paradigm of metal-catalyzed tyrosine nitration in vitro and in vivo.

Published in:

Metallomics, 2018, v. 10, n. 5, p. 679, doi. 10.1039/c7mt00348j

By:

Demicheli, Verónica;
Moreno, Diego M.;
Radi, Rafael

Publication type:

Article

Trypanosoma cruzi Mitochondrial Peroxiredoxin Promotes Infectivity in Macrophages and Attenuates Nifurtimox Toxicity.

Published in:

Frontiers in Cellular & Infection Microbiology, 2022, v. 11, p. 1, doi. 10.3389/fcimb.2022.749476

By:

Specker, Gabriela;
Estrada, Damián;
Radi, Rafael;
Piacenza, Lucía

Publication type:

Article

Lactate dehydrogenase activity and its isoenzymes in concentric layers of adult bovine and calf lenses.

Published in:

Current Eye Research, 1987, v. 6, n. 4, p. 555, doi. 10.3109/02713688709025213

By:

Sempol, David;
Osinaga, Edurado;
Zigman, Seymour;
Korc, Israel;
Korc, Beatriz;
Sans, Alicia;
Radi, Rafael;
Berretta, Juan C.;
Cayota, Alfonso;
Schwalb, Monica

Publication type:

Article

NADPH Phagocyte Oxidase Knockout Mice Control Trypanosoma cruzi Proliferation, but Develop Circulatory Collapse and Succumb to Infection.

Published in:

PLoS Neglected Tropical Diseases, 2012, v. 6, n. 2, p. 1, doi. 10.1371/journal.pntd.0001492

By:

Santiago, Helton C.;
Gonzalez Lombana, Claudia Z.;
Macedo, Juan P.;
Utsch, Lara;
Tafuri, Wagner L.;
Campagnole-Santos, Maria José;
Alves, Rosana O.;
Alves-Filho, José C. F.;
Romanha, Alvaro J.;
Cunha, Fernando Queiroz;
Teixeira, Mauro M.;
Radi, Rafael;
Vieira, Leda Q.

Publication type:

Article

NADPH Phagocyte Oxidase Knockout Mice Control Trypanosoma cruzi Proliferation, but Develop Circulatory Collapse and Succumb to Infection.

Published in:

PLoS Neglected Tropical Diseases, 2012, v. 6, n. 2, p. 1, doi. 10.1371/journal.pntd.0001492

By:

Santiago, Helton C.;
Lombana, Claudia Z. Gonzalez;
Macedo, Juan P.;
Utsch, Lara;
Tafuri, Wagner L.;
JoséCampagnole-Santos, Maria;
Alves, Rosana O.;
Alves-Filho, JoséC. F.;
Romanha, Alvaro J.;
Cunha, Fernando Queiroz;
Teixeira, Mauro M.;
Radi, Rafael;
Vieira, Leda Q.

Publication type:

Article

4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification.

Published in:

European Heart Journal, 2023, v. 44, n. 44, p. 4696, doi. 10.1093/eurheartj/ehad662

By:

Kiyuna, Ligia A;
Candido, Darlan S;
Bechara, Luiz R G;
Jesus, Itamar C G;
Ramalho, Lisley S;
Krum, Barbara;
Albuquerque, Ruda P;
Campos, Juliane C;
Bozi, Luiz H M;
Zambelli, Vanessa O;
Alves, Ariane N;
Campolo, Nicolás;
Mastrogiovanni, Mauricio;
Bartesaghi, Silvina;
Leyva, Alejandro;
Durán, Rosario;
Radi, Rafael;
Arantes, Guilherme M;
Cunha-Neto, Edécio;
Mori, Marcelo A

Publication type:

Article

Mitochondrial Dysfunction in SOD1<sup>G93A</sup>-Bearing Astrocytes Promotes Motor Neuron Degeneration: Prevention by Mitochondrial-Targeted Antioxidants.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 16, p. 4115, doi. 10.1523/JNEUROSCI.5308-07.2008

By:

Cassina, Patricia;
Cassina, Adriana;
Pehar, Mariana;
Castellanos, Raquel;
Gandelman, Mandi;
De León, Andrés;
Robinson, Kristine M.;
Mason, Ronald P.;
Beckman, Joseph S.;
Barbeito, Luis;
Radi, Rafael

Publication type:

Article

Mitochondrial Superoxide Production and Nuclear Factor Erythroid 2-Related Factor 2 Activation in p75 Neurotrophin Receptor-Induced Motor Neuron Apoptosis.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 29, p. 7777, doi. 10.1523/JNEUROSCI.0823-07.2007

By:

Pehar, Mariana;
Vargas, Marcelo R.;
Robinson, Kristine M.;
Cassina, Patricia;
Díaz-Amarilla, Pablo J.;
Hagen, Tory M.;
Radi, Rafael;
Barbeito, Luis;
Beckman, Joseph S.

Publication type:

Article

Plasmodium falciparum 2-Cys peroxiredoxin reacts with plasmoredoxin and peroxynitrite.

Published in:

Biological Chemistry, 2005, v. 386, n. 11, p. 1129, doi. 10.1515/BC.2005.129

By:

Nickel, Christine;
Trujillo, Madia;
Rahlfs, Stefan;
Deponte, Marcel;
Radi, Rafael;
Becker, Katja

Publication type:

Article

Correction: Nitro-Arachidonic Acid Prevents Angiotensin II Induced Mitochondrial Dysfunction in Kidney Proximal Tubular Cells.

Published in:

2016

By:

Sánchez-Calvo, Beatriz;
Cassina, Adriana;
Rios, Natalia;
Peluffo, Gonzalo;
Boggia, José;
Radi, Rafael;
Rubbo, Homero;
Trostchansky, Andrés

Publication type:

Correction Notice

Nitro-Arachidonic Acid Prevents Angiotensin II-Induced Mitochondrial Dysfunction in a Cell Line of Kidney Proximal Tubular Cells.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150459

By:

Sánchez-Calvo, Beatriz;
Cassina, Adriana;
Rios, Natalia;
Peluffo, Gonzalo;
Boggia, José;
Radi, Rafael;
Rubbo, Homero;
Trostchansky, Andres

Publication type:

Article

Cyclosporine A-induced nitration of tyrosine 34 MnSOD in endothelial cells: role of mitochondrial superoxide.

Published in:

Cardiovascular Research, 2010, v. 87, n. 2, p. 356, doi. 10.1093/cvr/cvq028

By:

Redondo-Horcajo, Mariano;
Romero, Natalia;
Martínez-Acedo, Pablo;
Martínez-Ruiz, Antonio;
Quijano, Celia;
Lourenço, Catia F.;
Movilla, Nieves;
Enríquez, Jose Antonio;
Rodríguez-Pascual, Fernando;
Rial, Eduardo;
Radi, Rafael;
Vázquez, Jesús;
Lamas, Santiago

Publication type:

Article

Genetic and transcriptomic evidences suggest ARO10 genes are involved in benzenoid biosynthesis by yeast.

Published in:

Yeast, 2020, v. 37, n. 9/10, p. 427, doi. 10.1002/yea.3508

By:

Valera, Maria Jose;
Zeida, Ari;
Boido, Eduardo;
Beltran, Gemma;
Torija, María Jesús;
Mas, Albert;
Radi, Rafael;
Dellacassa, Eduardo;
Carrau, Francisco

Publication type:

Article

The Effect of Fat Intake with Increased Omega-6-to-Omega-3 Polyunsaturated Fatty Acid Ratio in Animal Models of Early and Late Alzheimer's Disease-like Pathogenesis.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 17009, doi. 10.3390/ijms242317009

By:

Galeano, Pablo;
de Ceglia, Marialuisa;
Mastrogiovanni, Mauricio;
Campanelli, Lorenzo;
Medina-Vera, Dina;
Campolo, Nicolás;
Novack, Gisela V.;
Rosell-Valle, Cristina;
Suárez, Juan;
Aicardo, Adrián;
Campuzano, Karen;
Castaño, Eduardo M.;
Do Carmo, Sonia;
Cuello, A. Claudio;
Bartesaghi, Silvina;
Radi, Rafael;
Rodríguez de Fonseca, Fernando;
Morelli, Laura

Publication type:

Article

Radiolysis Studies of Oxidation and Nitration of Tyrosine and Some Other Biological Targets by Peroxynitrite-Derived Radicals.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1797, doi. 10.3390/ijms23031797

By:

Folkes, Lisa K.;
Bartesaghi, Silvina;
Trujillo, Madia;
Wardman, Peter;
Radi, Rafael

Publication type:

Article

Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia.

Published in:

Glia (0894-1491), 2017, v. 65, n. 9, p. 1521, doi. 10.1002/glia.23178

By:

Lepka, Klaudia;
Volbracht, Katrin;
Bill, Eckhard;
Schneider, Reiner;
Rios, Natalia;
Hildebrandt, Thomas;
Ingwersen, Jens;
Prozorovski, Timur;
Lillig, Christopher Horst;
van Horssen, Jack;
Steinman, Lawrence;
Hartung, Hans‐Peter;
Radi, Rafael;
Holmgren, Arne;
Aktas, Orhan;
Berndt, Carsten

Publication type:

Article

Peroxynitrite, a potent macrophage-derived oxidizing cytotoxin to combat invading pathogens.

Published in:

Biofactors, 2014, v. 40, n. 2, p. 215, doi. 10.1002/biof.1150

By:

Prolo, Carolina;
Álvarez, María Noel;
Radi, Rafael

Publication type:

Article

The Thiol-Modifier Effects of Organoselenium Compounds and Their Cytoprotective Actions in Neuronal Cells.

Published in:

Neurochemical Research, 2021, v. 46, n. 1, p. 120, doi. 10.1007/s11064-020-03026-x

By:

Galant, Letícia Selinger;
Rafique, Jamal;
Braga, Antônio Luiz;
Braga, Felipe Camargo;
Saba, Sumbal;
Radi, Rafael;
da Rocha, João Batista Teixeira;
Santi, Claudio;
Monsalve, Maria;
Farina, Marcelo;
de Bem, Andreza Fabro

Publication type:

Article

Biochemistry of protein tyrosine nitration in cardiovascular pathology

Published in:

Cardiovascular Research, 2007, v. 75, n. 2, p. 291, doi. 10.1016/j.cardiores.2007.04.024

By:

Peluffo, Gonzalo;
Radi, Rafael

Publication type:

Article

Neuronal Parasitism, Early Myenteric Neurons Depopulation and Continuous Axonal Networking Damage as Underlying Mechanisms of the Experimental Intestinal Chagas' Disease.

Published in:

Frontiers in Cellular & Infection Microbiology, 2020, v. 10, p. N.PAG, doi. 10.3389/fcimb.2020.583899

By:

Ricci, Mayra Fernanda;
Béla, Samantha Ribeiro;
Moraes, Michele Macedo;
Bahia, Maria Terezinha;
Mazzeti, Ana Lia;
Oliveira, Anny Caroline Silva;
Andrade, Luciana Oliveira;
Radí, Rafael;
Piacenza, Lucía;
Arantes, Rosa Maria Esteves

Publication type:

Article

Biological Antioxidant Defenses.

Published in:

Toxicology & Industrial Health, 1993, v. 9, n. 1/2, p. 53, doi. 10.1177/074823379300900206

By:

Radi, Rafael

Publication type:

Article

Mitochondrial protein tyrosine nitration.

Published in:

Free Radical Research, 2011, v. 45, n. 1, p. 37, doi. 10.3109/10715762.2010.516254

By:

Castro, Laura;
Demicheli, Verónica;
Tórtora, Verónica;
Radi, Rafael

Publication type:

Article

Peroxynitrite decay in the presence of hydrogen peroxide, mannitol and ethanol: A reappraisal.

Published in:

Free Radical Research, 2001, v. 34, n. 5, p. 467, doi. 10.1080/10715760100300411

By:

Alvarez, Beatriz;
Radi, Rafael

Publication type:

Article

Peroxynitrite-Induced Cytotoxicity in PC12 Cells: Evidence for an Apoptotic Mechanism Differentially Modulated by Neurotrophic Factors.

Published in:

Journal of Neurochemistry, 1995, v. 65, n. 4, p. 1543, doi. 10.1046/j.1471-4159.1995.65041543.x

By:

Estévez, Alvaro G.;
Radi, Rafael;
Barbeito, Luis;
Shin, Jordan T.;
Thompson, John A.;
Beckman, Joseph S.

Publication type:

Article

Macromolecular crowding and bicarbonate enhance the hydrogen peroxide-induced inactivation of glyceraldehyde-3-phosphate dehydrogenase.

Published in:

Biochemical Journal, 2024, v. 481, n. 23, p. 1855, doi. 10.1042/BCJ20240597

By:

Bloemen, Rebecca H. J.;
Radi, Rafael;
Davies, Michael J.;
Fuentes-Lemus, Eduardo

Publication type:

Article

Cardiomyocyte diffusible redox mediators control Trypanosoma cruzi infection: role of parasite mitochondrial iron superoxide dismutase.

Published in:

Biochemical Journal, 2018, v. 475, n. 7, p. 1235, doi. 10.1042/BCJ20170698

By:

Estrada, Damián;
Specker, Gabriela;
Martínez, Alejandra;
Pereira Dias, Patricia;
Hissa, Barbara;
Andrade, Luciana O.;
Radi, Rafael;
Piacenza, Lucía

Publication type:

Article

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics.

Published in:

Nature Reviews Drug Discovery, 2007, v. 6, n. 8, p. 662, doi. 10.1038/nrd2222

By:

Szabó, Csaba;
Ischiropoulos, Harry;
Radi, Rafael

Publication type:

Article

Early Trypanosoma cruzi Infection Triggers mTORC1-Mediated Respiration Increase and Mitochondrial Biogenesis in Human Primary Cardiomyocytes.

Published in:

Frontiers in Microbiology, 2018, p. 1, doi. 10.3389/fmicb.2018.01889

By:

Libisch, M. Gabriela;
Faral-Tello, Paula;
Garg, Nisha J.;
Radi, Rafael;
Piacenza, Lucía;
Robello, Carlos

Publication type:

Article

Red blood cells in the metabolism of nitric oxide-derived peroxynitrite.

Published in:

IUBMB Life, 2006, v. 58, n. 10, p. 572, doi. 10.1080/15216540600936549

By:

Romero, Natalia;
Denicola, Ana;
Radi, Rafael

Publication type:

Article

How I became a Biochemist.

Published in:

IUBMB Life, 2006, v. 58, n. 9, p. 559, doi. 10.1080/15216540600840899

By:

Radi, Rafael

Publication type:

Article

Olives and Olive Oil Are Sources of Electrophilic Fatty Acid Nitroalkenes.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0084884

By:

Fazzari, Marco;
Trostchansky, Andrés;
Schopfer, Francisco J.;
Salvatore, Sonia R.;
Sánchez-Calvo, Beatriz;
Vitturi, Dario;
Valderrama, Raquel;
Barroso, Juan B.;
Radi, Rafael;
Freeman, Bruce A.;
Rubbo, Homero

Publication type:

Article

Modulation of Astrocytic Mitochondrial Function by Dichloroacetate Improves Survival and Motor Performance in Inherited Amyotrophic Lateral Sclerosis.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034776

By:

Miquel, Ernesto;
Cassina, Adriana;
Martínez-Palma, Laura;
Bolatto, Carmen;
Trías, Emiliano;
Gandelman, Mandi;
Radi, Rafael;
Barbeito, Luis;
Cassina, Patricia

Publication type:

Article

In memoriam: Emeritus Professor Robin L. Willson.

Published in:

Free Radical Research, 2022, v. 56, n. 7/8, p. 572, doi. 10.1080/10715762.2022.2140273

By:

Davies, Michael J;
Davies, Kelvin J A;
Halliwell, Barry;
Jackson, Malcolm J;
Mann, Giovanni E;
Poli, Giuseppe;
Radi, Rafael;
Riley, Patrick A;
Sies, Helmut;
Ward, John F;
Wardman, Peter;
Willson, John

Publication type:

Article

The effects of nitric oxide or oxygen on the stable products formed from the tyrosine phenoxyl radical.

Published in:

Free Radical Research, 2021, v. 55, n. 2, p. 141, doi. 10.1080/10715762.2020.1870684

By:

Folkes, Lisa K.;
Bartesaghi, Silvina;
Trujillo, Madia;
Wardman, Peter;
Radi, Rafael

Publication type:

Article

A computational investigation of the reactions of tyrosyl, tryptophanyl, and cysteinyl radicals with nitric oxide and molecular oxygen.

Published in:

Free Radical Research, 2019, v. 53, n. 1, p. 18, doi. 10.1080/10715762.2018.1541322

By:

Pedron, Federico N.;
Bartesaghi, Silvina;
Estrin, Darío A.;
Radi, Rafael;
Zeida, Ari

Publication type:

Article

Propagation of free-radical reactions in concentrated protein solutions.

Published in:

Free Radical Research, 2018, v. 52, n. 2, p. 159, doi. 10.1080/10715762.2017.1420905

By:

Aicardo, Adrián;
Mastrogiovanni, Mauricio;
Cassina, Adriana;
Radi, Rafael

Publication type:

Article

Special issue on “Free Radical and Redox Biochemistry of Thiols”.

Published in:

2016

By:

Radi, Rafael;
Trujillo, Madia

Publication type:

Editorial

One- and two-electron oxidation of thiols: mechanisms, kinetics and biological fates.

Published in:

Free Radical Research, 2016, v. 50, n. 2, p. 150, doi. 10.3109/10715762.2015.1089988

By:

Trujillo, Madia;
Alvarez, Beatriz;
Radi, Rafael

Publication type:

Article

Kinetics of oxidation of tyrosine by a model alkoxyl radical.

Published in:

Free Radical Research, 2012, v. 46, n. 9, p. 1150, doi. 10.3109/10715762.2012.695868

By:

Folkes, Lisa K.;
Bartesaghi, Silvina;
Trujillo, Madia;
Radi, Rafael;
Wardman, Peter

Publication type:

Article

Cardiomyocyte oxidants production may signal to T. cruzi intracellular development.

Published in:

PLoS Neglected Tropical Diseases, 2017, v. 11, n. 8, p. 1, doi. 10.1371/journal.pntd.0005852

By:

Dias, Patrícia Pereira;
Capila, Rhayanne Figueiredo;
do Couto, Natália Fernanda;
Estrada, Damían;
Gadelha, Fernanda Ramos;
Radi, Rafael;
Piacenza, Lucía;
Andrade, Luciana O.

Publication type:

Article

Metal-catalyzed protein tyrosine nitration in biological systems.

Published in:

Redox Report, 2014, v. 19, n. 6, p. 221, doi. 10.1179/1351000214Y.0000000099

By:

Campolo, Nicolás;
Bartesaghi, Silvina;
Radi, Rafael

Publication type:

Article

Septic diaphragmatic dysfunction is prevented by Mn(III)porphyrin therapy and inducible nitric oxide synthase inhibition.

Published in:

2004

By:

Nin, Nicolás;
Cassina, Adriana;
Boggia, José;
Alfonso, Evangelina;
Botti, Horacio;
Peluffo, Gonzalo;
Trostchansky, Andrés;
Batthyány, Carlos;
Radi, Rafael;
Rubbo, Homero;
Hurtado, F. Javier;
Nin, Nicolás;
Boggia, José;
Trostchansky, Andrés;
Batthyány, Carlos

Publication type:

journal article

3-Nitrotyrosine and related derivatives in proteins: precursors, radical intermediates and impact in function.

Published in:

Essays in Biochemistry, 2020, v. 64, n. 1, p. 111, doi. 10.1042/EBC20190052

By:

Campolo, Nicolas;
Issoglio, Federico M.;
Estrin, Dario A.;
Bartesaghi, Silvina;
Radi, Rafael

Publication type:

Article