Works matching AU Rabinowitz, Joshua D.

Results: 61

CLN3 disease disrupts very early postnatal hippocampal maturation.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-02010-1

By:

Singh, Jeet B.;
Burris, Devin M.;
Bhuyan, Sangeetha;
Thurston, Tegan;
Oschmann, Anna;
Jankowski, Connor;
Lu, Wenyun;
Rabinowitz, Joshua D.;
Ahrens-Nicklas, Rebecca C.

Publication type:

Article

Quiescent Fibroblasts Exhibit High Metabolic Activity.

Published in:

PLoS Biology, 2010, v. 8, n. 10, p. 1, doi. 10.1371/journal.pbio.1000514

By:

Lemons, Johanna M. S.;
Xiao-Jiang Feng;
Bennett, Bryson D.;
Legesse-Miller, Aster;
Johnson, Elizabeth L.;
Raitman, Irene;
Pollina, Elizabeth A.;
Rabitz, Herschel A.;
Rabinowitz, Joshua D.;
Coller, Hilary A.

Publication type:

Article

Ammonium Toxicity and Potassium Limitation in Yeast.

Published in:

PLoS Biology, 2006, v. 4, n. 11, p. 2012, doi. 10.1371/journal.pbio.0040351

By:

Hess, David C.;
Wenyun Lu;
Rabinowitz, Joshua D.;
Botstein, David

Publication type:

Article

Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50157-8

By:

Lan, Taijin;
Arastu, Sara;
Lam, Jarrick;
Kim, Hyungsin;
Wang, Wenping;
Wang, Samuel;
Bhatt, Vrushank;
Lopes, Eduardo Cararo;
Hu, Zhixian;
Sun, Michael;
Luo, Xuefei;
Ghergurovich, Jonathan M.;
Su, Xiaoyang;
Rabinowitz, Joshua D.;
White, Eileen;
Guo, Jessie Yanxiang

Publication type:

Article

CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production.

Published in:

Cells (2073-4409), 2021, v. 10, n. 9, p. 2334, doi. 10.3390/cells10092334

By:

Garcia-Canaveras, Juan C.;
Heo, David;
Trefely, Sophie;
Leferovich, John;
Xu, Chong;
Philipson, Benjamin I.;
Ghassemi, Saba;
Milone, Michael C.;
Moon, Edmund K.;
Snyder, Nathaniel W.;
June, Carl H.;
Rabinowitz, Joshua D.;
O'Connor, Roddy S.

Publication type:

Article

Ras-driven cancer cells can scavenge exogenous lipids to support their proliferation.

Published in:

2012

By:

Kamphorst, Jurre J.;
Cross, Justin R.;
Jing Fan;
Wenyun Lu;
White, Eileen;
Thompson, Craig B.;
Rabinowitz, Joshua D.

Publication type:

Abstract

A tps1Δ persister-like state in Saccharomyces cerevisiae is regulated by MKT1.

Published in:

PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0233779

By:

Gibney, Patrick A.;
Chen, Anqi;
Schieler, Ariel;
Chen, Jonathan C.;
Xu, Yifan;
Hendrickson, David G.;
McIsaac, R. Scott;
Rabinowitz, Joshua D.;
Botstein, David

Publication type:

Article

Inhibition of de novo pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer.

Published in:

International Journal of Biological Sciences, 2021, v. 17, n. 9, p. 2240, doi. 10.7150/ijbs.60473

By:

Thuy Phan;
Nguyen, Vu H.;
Buettner, Ralf;
Morales, Corey;
Lifeng Yang;
Wong, Paul;
Tsai, Weiman;
Salazar, Marcela d'Alincourt;
Ziv Gil;
Diamond, Don J.;
Rabinowitz, Joshua D.;
Rosen, Steven;
Melstrom, Laleh G.

Publication type:

Article

Genetic Basis of Metabolome Variation in Yeast.

Published in:

PLoS Genetics, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pgen.1004142

By:

Breunig, Jeffrey S.;
Hackett, Sean R.;
Rabinowitz, Joshua D.;
Kruglyak, Leonid

Publication type:

Article

Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice.

Published in:

2018

By:

Lanaspa, Miguel A.;
Andres-Hernando, Ana;
Orlicky, David J.;
Cicerchi, Christina;
Jang, Cholsoon;
Nanxing Li;
Milagres, Tamara;
Masanari Kuwabara;
Wempe, Michael F.;
Rabinowitz, Joshua D.;
Johnson, Richard J.;
Tolan, Dean R.;
Li, Nanxing;
Kuwabara, Masanari

Publication type:

journal article

Enhancing Molecular Discovery Using Descriptor-Free Rearrangement Clustering Techniques for Sparse Data Sets.

Published in:

AIChE Journal, 2010, v. 56, n. 2, p. 405, doi. 10.1002/aic.11986

By:

DiMaggio Jr., Peter A.;
McAllister, Scott R.;
Floudas, Christodoulos A.;
Xiao-Jiaag Feng;
Genyoan Li;
Rabinowitz, Joshua D.;
Rabitz, Herschel A.

Publication type:

Article

Metabolic excretion associated with nutrient–growth dysregulation promotes the rapid evolution of an overt metabolic defect.

Published in:

PLoS Biology, 2020, v. 18, n. 8, p. 1, doi. 10.1371/journal.pbio.3000757

By:

Green, Robin;
Sonal;
Wang, Lin;
Hart, Samuel F. M.;
Lu, Wenyun;
Skelding, David;
Burton, Justin C.;
Mi, Hanbing;
Capel, Aric;
Chen, Hung Alex;
Lin, Aaron;
Subramaniam, Arvind R.;
Rabinowitz, Joshua D.;
Shou, Wenying

Publication type:

Article

Downregulation of the tyrosine degradation pathway extends Drosophila lifespan.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.58053

By:

Parkhitko, Andrey A.;
Ramesh, Divya;
Lin Wang;
Leshchiner, Dmitry;
Filine, Elizabeth;
Binari, Richard;
Olsen, Abby L.;
Asara, John M.;
Cracan, Valentin;
Rabinowitz, Joshua D.;
Brockmann, Axel;
Perrimon, Norbert

Publication type:

Article

Monitoring mammalian mitochondrial translation with MitoRiboSeq.

Published in:

Nature Protocols, 2021, v. 16, n. 6, p. 2802, doi. 10.1038/s41596-021-00517-1

By:

Li, Sophia Hsin-Jung;
Nofal, Michel;
Parsons, Lance R.;
Rabinowitz, Joshua D.;
Gitai, Zemer

Publication type:

Article

A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0176085

By:

Choi, Joonhyuk;
Rajagopal, Abbhirami;
Xu, Yi-Fan;
Rabinowitz, Joshua D.;
O’Shea, Erin K.

Publication type:

Article

The return of metabolism: biochemistry and physiology of the pentose phosphate pathway.

Published in:

Biological Reviews, 2015, v. 90, n. 3, p. 927, doi. 10.1111/brv.12140

By:

Stincone, Anna;
Prigione, Alessandro;
Cramer, Thorsten;
Wamelink, Mirjam M. C.;
Campbell, Kate;
Cheung, Eric;
Olin‐Sandoval, Viridiana;
Grüning, Nana‐Maria;
Krüger, Antje;
Tauqeer Alam, Mohammad;
Keller, Markus A.;
Breitenbach, Michael;
Brindle, Kevin M.;
Rabinowitz, Joshua D.;
Ralser, Markus

Publication type:

Article

4582 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) DEPLETION MUST BE SEVERE TO INDUCE CARDIAC DYSFUNCTION AND EVENTUAL FAILURE.

Published in:

2020

By:

Luongo, Timothy;
Wang, Lin;
Chellappa, Karthikeyani;
McReynolds, Melanie R.;
Kelly, Daniel P.;
Rabinowitz, Joshua D.;
Baur, Joseph A.

Publication type:

Abstract

Author Correction: An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis.

Published in:

2024

By:

Tran, Vinh G.;
Mishra, Somesh;
Bhagwat, Sarang S.;
Shafaei, Saman;
Shen, Yihui;
Allen, Jayne L.;
Crosly, Benjamin A.;
Tan, Shih-I;
Fatma, Zia;
Rabinowitz, Joshua D.;
Guest, Jeremy S.;
Singh, Vijay;
Zhao, Huimin

Publication type:

Correction Notice

An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41616-9

By:

Tran, Vinh G.;
Mishra, Somesh;
Bhagwat, Sarang S.;
Shafaei, Saman;
Shen, Yihui;
Allen, Jayne L.;
Crosly, Benjamin A.;
Tan, Shih-I;
Fatma, Zia;
Rabinowitz, Joshua D.;
Guest, Jeremy S.;
Singh, Vijay;
Zhao, Huimin

Publication type:

Article

Cellular metabolomics of Escherchia coli.

Published in:

Expert Review of Proteomics, 2007, v. 4, n. 2, p. 187, doi. 10.1586/14789450.4.2.187

By:

Rabinowitz, Joshua D.

Publication type:

Article

Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain.

Published in:

Journal of Neurochemistry, 2018, v. 145, n. 5, p. 362, doi. 10.1111/jnc.14319

By:

McKee, Sarah E.;
Zhang, Sisi;
Chen, Li;
Rabinowitz, Joshua D.;
Reyes, Teresa M.

Publication type:

Article

Saturated Very Long Chain Fatty Acids Are Required for the Production of Infectious Human Cytomegalovirus Progeny

Published in:

PLoS Pathogens, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.ppat.1003333

By:

Koyuncu, Emre;
Purdy, John G.;
Rabinowitz, Joshua D.;
Shenk, Thomas

Publication type:

Article

Divergent Effects of Human Cytomegalovirus and Herpes Simplex Virus-1 on Cellular Metabolism.

Published in:

PLoS Pathogens, 2011, v. 7, n. 7, p. 1, doi. 10.1371/journal.ppat.1002124

By:

Vastag, Livia;
Koyuncu, Emre;
Grady, Sarah L.;
Shenk, Thomas E.;
Rabinowitz, Joshua D.

Publication type:

Article

Dynamics of the Cellular Metabolome during Human Cytomegalovirus Infection.

Published in:

PLoS Pathogens, 2006, v. 2, n. 12, p. 1165, doi. 10.1371/journal.ppat.0020132

By:

Munger, Joshua;
Bajad, Sunil U.;
Coller, Hilary A.;
Shenk, Thomas;
Rabinowitz, Joshua D.

Publication type:

Article

Metabolic decisions in development and disease—a Keystone Symposia report.

Published in:

Annals of the New York Academy of Sciences, 2021, v. 1506, n. 1, p. 55, doi. 10.1111/nyas.14678

By:

Cable, Jennifer;
Pourquié, Olivier;
Wellen, Kathryn E.;
Finley, Lydia W. S.;
Aulehla, Alexander;
Gould, Alex P.;
Teleman, Aurelio;
Tu, William B.;
Garrett, Wendy Sarah;
Miguel‐Aliaga, Irene;
Perrimon, Norbert;
Hooper, Lora V.;
Walhout, A. J. Marian;
Wei, Wei;
Alexandrov, Theodore;
Erez, Ayelet;
Ralser, Markus;
Rabinowitz, Joshua D.;
Hemalatha, Anupama;
Gutiérrez‐Pérez, Paula

Publication type:

Article

Achieving Optimal Growth through Product Feedback Inhibition in Metabolism.

Published in:

PLoS Computational Biology, 2010, v. 6, n. 6, p. 1, doi. 10.1371/journal.pcbi.1000802

By:

Goyal, Sidhartha;
Jie Yuan;
Chen, Thomas;
Rabinowitz, Joshua D.;
Wingreen, Ned S.

Publication type:

Article

Robustness in Glyoxylate Bypass Regulation.

Published in:

PLoS Computational Biology, 2009, v. 5, n. 3, p. 1, doi. 10.1371/journal.pcbi.1000297

By:

Shinar, Guy;
Rabinowitz, Joshua D.;
Alon, Uri

Publication type:

Article

Coordinated Concentration Changes of Transcripts and Metabolites in Saccharomyces cerevisiae.

Published in:

PLoS Computational Biology, 2009, v. 5, n. 1, p. 1, doi. 10.1371/journal.pcbi.1000270

By:

Bradley, Patrick H.;
Brauer, Matthew J.;
Rabinowitz, Joshua D.;
Troyanskaya, Olga G.

Publication type:

Article

Tissue-specific reprogramming of glutamine metabolism maintains tolerance to sepsis.

Published in:

PLoS ONE, 2023, v. 18, n. 7, p. 1, doi. 10.1371/journal.pone.0286525

By:

Leitner, Brooks P.;
Lee, Won D.;
Zhu, Wanling;
Zhang, Xinyi;
Gaspar, Rafael C.;
Li, Zongyu;
Rabinowitz, Joshua D.;
Perry, Rachel J.

Publication type:

Article

Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia.

Published in:

Molecular Systems Biology, 2013, v. 9, n. 1, p. 1, doi. 10.1038/msb.2013.65

By:

Fan, Jing;
Kamphorst, Jurre J;
Mathew, Robin;
Chung, Michelle K;
White, Eileen;
Shlomi, Tomer;
Rabinowitz, Joshua D

Publication type:

Article

Nucleotide degradation and ribose salvage in yeast.

Published in:

Molecular Systems Biology, 2013, v. 9, n. 1, p. 1, doi. 10.1038/msb.2013.21

By:

Xu, Yi‐Fan;
Létisse, Fabien;
Absalan, Farnaz;
Lu, Wenyun;
Kuznetsova, Ekaterina;
Brown, Greg;
Caudy, Amy A;
Yakunin, Alexander F;
Broach, James R;
Rabinowitz, Joshua D

Publication type:

Article

Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli.

Published in:

Molecular Systems Biology, 2010, v. 6, n. 1, p. 1, doi. 10.1038/msb.2010.33

By:

Goodarzi, Hani;
Bennett, Bryson D;
Amini, Sasan;
Reaves, Marshall L;
Hottes, Alison K;
Rabinowitz, Joshua D;
Tavazoie, Saeed

Publication type:

Article

Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli.

Published in:

Molecular Systems Biology, 2009, v. 5, n. 1, p. 302, doi. 10.1038/msb.2009.60

By:

Yuan, Jie;
Doucette, Christopher D;
Fowler, William U;
Feng, Xiao‐Jiang;
Piazza, Matthew;
Rabitz, Herschel A;
Wingreen, Ned S;
Rabinowitz, Joshua D

Publication type:

Article

Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041831

By:

Bray, Kevin;
Mathew, Robin;
Lau, Alexandria;
Kamphorst, Jurre J.;
Fan, Jing;
Chen, Jim;
Chen, Hsin-Yi;
Ghavami, Anahita;
Stein, Mark;
DiPaola, Robert S.;
Zhang, Donna;
Rabinowitz, Joshua D.;
White, Eileen

Publication type:

Article

Remodeling of the Metabolome during Early Frog Development.

Published in:

PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0016881

By:

Vastag, Livia;
Jorgensen, Paul;
Peshkin, Leonid;
Wei, Ru;
Rabinowitz, Joshua D.;
W.^Kirschner, Marc

Publication type:

Article

A network flow model for biclustering via optimal re-ordering of data matrices.

Published in:

Journal of Global Optimization, 2010, v. 47, n. 3, p. 343, doi. 10.1007/s10898-008-9349-z

By:

DiMaggio Jr., Peter A.;
McAllister, Scott R.;
Floudas, Christodoulos A.;
Xiao-Jiang Feng;
Rabinowitz, Joshua D.;
Rabitz, Herschel A.

Publication type:

Article

Quantitative flux analysis reveals folate-dependent NADPH production.

Published in:

Nature, 2014, v. 510, n. 7504, p. 298, doi. 10.1038/nature13236

By:

Fan, Jing;
Ye, Jiangbin;
Kamphorst, Jurre J.;
Shlomi, Tomer;
Thompson, Craig B.;
Rabinowitz, Joshua D.

Publication type:

Article

Systems biology: Metabolite turns master regulator.

Published in:

Nature, 2013, v. 500, n. 7462, p. 283, doi. 10.1038/nature12544

By:

Rabinowitz, Joshua D.;
Silhavy, Thomas J.

Publication type:

Article

Pyrimidine homeostasis is accomplished by directed overflow metabolism.

Published in:

Nature, 2013, v. 500, n. 7461, p. 237, doi. 10.1038/nature12445

By:

Reaves, Marshall Louis;
Young, Brian D.;
Hosios, Aaron M.;
Xu, Yi-Fan;
Rabinowitz, Joshua D.

Publication type:

Article

Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum.

Published in:

Nature, 2013, v. 497, n. 7451, p. 652, doi. 10.1038/nature12164

By:

Olszewski, Kellen L.;
Mather, Michael W.;
Morrisey, Joanne M.;
Garcia, Benjamin A.;
Vaidya, Akhil B.;
Rabinowitz, Joshua D.;
Llinás, Manuel

Publication type:

Article

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.

Published in:

Nature, 2013, v. 497, n. 7451, p. 633, doi. 10.1038/nature12138

By:

Commisso, Cosimo;
Davidson, Shawn M.;
Soydaner-Azeloglu, Rengin G.;
Parker, Seth J.;
Kamphorst, Jurre J.;
Hackett, Sean;
Grabocka, Elda;
Nofal, Michel;
Drebin, Jeffrey A.;
Thompson, Craig B.;
Rabinowitz, Joshua D.;
Metallo, Christian M.;
Vander Heiden, Matthew G.;
Bar-Sagi, Dafna

Publication type:

Article

Branched tricarboxylic acid metabolism in Plasmodium falciparum.

Published in:

2011

By:

Olszewski, Kellen L.;
Mather, Michael W.;
Morrisey, Joanne M.;
Garcia, Benjamin A.;
Vaidya, Akhil B.;
Rabinowitz, Joshua D.;
Llinás, Manuel

Publication type:

Correction Notice

Branched tricarboxylic acid metabolism in Plasmodium falciparum.

Published in:

Nature, 2010, v. 466, n. 7307, p. 774, doi. 10.1038/nature09301

By:

Olszewski, Kellen L.;
Mather, Michael W.;
Morrisey, Joanne M.;
Garcia, Benjamin A.;
Vaidya, Akhil B.;
Rabinowitz, Joshua D.;
Llinás, Manuel

Publication type:

Article

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Published in:

Nature, 2010, v. 465, n. 7300, p. 966, doi. 10.1038/nature09132

By:

Dang, Lenny;
White, David W.;
Gross, Stefan;
Bennett, Bryson D.;
Bittinger, Mark A.;
Driggers, Edward M.;
Fantin, Valeria R.;
Jang, Hyun Gyung;
Jin, Shengfang;
Keenan, Marie C.;
Marks, Kevin M.;
Prins, Robert M.;
Ward, Patrick S.;
Yen, Katharine E.;
Liau, Linda M.;
Rabinowitz, Joshua D.;
Cantley, Lewis C.;
Thompson, Craig B.;
Vander Heiden, Matthew G.;
Su, Shinsan M.

Publication type:

Article

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Published in:

Nature, 2009, v. 462, n. 7274, p. 739, doi. 10.1038/nature08617

By:

Dang, Lenny;
White, David W.;
Gross, Stefan;
Bennett, Bryson D.;
Bittinger, Mark A.;
Driggers, Edward M.;
Fantin, Valeria R.;
Hyun Gyung Jang;
Shengfang Jin;
Keenan, Marie C.;
Marks, Kevin M.;
Prins, Robert M.;
Ward, Patrick S.;
Yen, Katharine E.;
Liau, Linda M.;
Rabinowitz, Joshua D.;
Cantley, Lewis C.;
Thompson, Craig B.;
Vander Heiden, Matthew G.;
Su, Shinsan M.

Publication type:

Article

Partners in theWarburg effect.

Published in:

2016

By:

RABINOWITZ, JOSHUA D.;
COLLER, HILARY A.

Publication type:

Opinion

Selected Ion Monitoring for Orbitrap-Based Metabolomics.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 4, p. 184, doi. 10.3390/metabo14040184

By:

Lu, Wenyun;
McBride, Matthew J.;
Lee, Won Dong;
Xing, Xi;
Xu, Xincheng;
Li, Xi;
Oschmann, Anna M.;
Shen, Yihui;
Bartman, Caroline;
Rabinowitz, Joshua D.

Publication type:

Article

OPTIMAL METHODS FOR RE-ORDERING DATA MATRICES IN SYSTEMS BIOLOGY AND DRUG DISCOVERY APPLICATIONS.

Published in:

Biophysical Reviews & Letters, 2008, v. 3, n. 1/2, p. 19, doi. 10.1142/S1793048008000605

By:

DIMAGGIO JR., PETER A.;
MCALLISTER, SCOTT R.;
FLOUDAS, CHRISTODOULOS A.;
FENG, XIAO-JIANG;
RABINOWITZ, JOSHUA D.;
RABITZ, HERSCHEL A.

Publication type:

Article

Metabolism: Cancer mistunes methylation.

Published in:

Nature Chemical Biology, 2013, v. 9, n. 5, p. 293, doi. 10.1038/nchembio.1234

By:

Shlomi, Tomer;
Rabinowitz, Joshua D

Publication type:

Article

Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase.

Published in:

Nature Chemical Biology, 2012, v. 8, n. 6, p. 562, doi. 10.1038/nchembio.941

By:

Xu, Yi-Fan;
Amador-Noguez, Daniel;
Reaves, Marshall Louis;
Feng, Xiao-Jiang;
Rabinowitz, Joshua D

Publication type:

Article