Found: 41
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Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Brown fat activation mitigates alcohol-induced liver steatosis and injury in mice.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity.
- Published in:
- 2017
- By:
- Publication type:
- journal article
New Antidiabetes Agent Targeting Both Mitochondrial Uncoupling and Pyruvate Catabolism: Two Birds With One Stone.
- Published in:
- 2019
- By:
- Publication type:
- journal article
4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls β-Cell Mass.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Leptin signaling and leptin resistance.
- Published in:
- Frontiers of Medicine, 2013, v. 7, n. 2, p. 207, doi. 10.1007/s11684-013-0263-5
- By:
- Publication type:
- Article
Biliary NIK promotes ductular reaction and liver injury and fibrosis in mice.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32575-8
- By:
- Publication type:
- Article
Human SH2B1 mutations are associated with maladaptive behaviors and obesity.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 12, p. 4732, doi. 10.1172/JCI62696
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- Publication type:
- Article
A link between protein translation and body weight.
- Published in:
- Journal of Clinical Investigation, 2007, v. 117, n. 2, p. 310, doi. 10.1172/JCI31289
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- Publication type:
- Article
Neuronal SH2B1 is essential for controlling energy and glucose homeostasis.
- Published in:
- Journal of Clinical Investigation, 2007, v. 117, n. 2, p. 397, doi. 10.1172/JCI29417
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- Publication type:
- Article
Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22924-4
- By:
- Publication type:
- Article
NF-?B-inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action.
- Published in:
- Nature Medicine, 2012, v. 18, n. 6, p. 943, doi. 10.1038/nm.2756
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- Publication type:
- Article
Brain regulation of energy balance and body weight.
- Published in:
- Reviews in Endocrine & Metabolic Disorders, 2013, v. 14, n. 4, p. 387, doi. 10.1007/s11154-013-9261-9
- By:
- Publication type:
- Article
The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus.
- Published in:
- Obesity Facts: The European Journal of Obesity, 2018, v. 11, n. 2, p. 93, doi. 10.1159/000486962
- By:
- Publication type:
- Article
Glucose Rapidly Induces Different Forms of Excitatory Synaptic Plasticity in Hypothalamic POMC Neurons.
- Published in:
- PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105080
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- Publication type:
- Article
Hepatic SH2B1 and SH2B2 Regulate Liver Lipid Metabolism and VLDL Secretion in Mice.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083269
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- Publication type:
- Article
Glucose Enhances Leptin Signaling through Modulation of AMPK Activity.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031636
- By:
- Publication type:
- Article
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08581-8
- By:
- Publication type:
- Article
Leptin Induces Epigenetic Regulation of Transient Receptor Potential Melastatin 7 in Rat Adrenal Pheochromocytoma Cells.
- Published in:
- American Journal of Respiratory Cell & Molecular Biology, 2021, v. 65, n. 2, p. 214, doi. 10.1165/rcmb.2020-0374OC
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- Publication type:
- Article
Targeting the Hippo- Yes-Associated Protein/Transcriptional Coactivator with PDZ-Binding Motif Signaling Pathway in Primary Liver Cancer Therapy.
- Published in:
- Onco, 2024, v. 4, n. 3, p. 217, doi. 10.3390/onco4030016
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- Publication type:
- Article
SH2B1 Defends Against Energy Imbalance, Obesity, and Metabolic Disease via a Paraventricular Hypothalamus→Dorsal Raphe Nucleus Neurocircuit.
- Published in:
- Advanced Science, 2024, v. 11, n. 31, p. 1, doi. 10.1002/advs.202400437
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- Publication type:
- Article
Adipose METTL14‐Elicited N<sup>6</sup>‐Methyladenosine Promotes Obesity, Insulin Resistance, and NAFLD Through Suppressing β Adrenergic Signaling and Lipolysis.
- Published in:
- Advanced Science, 2023, v. 10, n. 28, p. 1, doi. 10.1002/advs.202301645
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- Publication type:
- Article
A critical role for hepatic protein arginine methyltransferase 1 isoform 2 in glycemic control.
- Published in:
- FASEB Journal, 2020, v. 34, n. 11, p. 14863, doi. 10.1096/fj.202001061R
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- Publication type:
- Article
Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression.
- Published in:
- FASEB Journal, 2018, v. 32, n. 4, p. 1830, doi. 10.1096/fj.201700831R
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- Publication type:
- Article
A small-molecule inhibitor of NF-κB-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury.
- Published in:
- FASEB Journal, 2017, v. 31, n. 2, p. 711, doi. 10.1096/fj.201600840R
- By:
- Publication type:
- Article
Clinopodium chinense Attenuates Palmitic Acid-Induced Vascular Endothelial Inflammation and Insulin Resistance through TLR4-Mediated NF-κB and MAPK Pathways.
- Published in:
- American Journal of Chinese Medicine, 2019, v. 47, n. 1, p. 97, doi. 10.1142/S0192415X19500058
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- Publication type:
- Article
Hepatic IRE1α regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARα axis signalling.
- Published in:
- Nature Communications, 2014, v. 5, n. 3, p. 3528, doi. 10.1038/ncomms4528
- By:
- Publication type:
- Article
Neuronal SH2B1 Is a Key Positive Regulator of Leptin Regulation of Energy and Glucose Homeostasis.
- Published in:
- Diabetes, 2007, v. 56, p. A71
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- Publication type:
- Article
Mechanisms of SH2B1-Stimulation of Insulin Signaling.
- Published in:
- Diabetes, 2007, v. 56, p. A36
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- Publication type:
- Article
Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis.
- Published in:
- Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05309-y
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- Publication type:
- Article
Author Correction: Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease.
- Published in:
- 2020
- By:
- Publication type:
- Correction Notice
Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15328-3
- By:
- Publication type:
- Article
1859-P: Hepatic NIK Augments Hepatocyte Ferroptosis and Hepatic Inflammation in Liver Disease.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1859-P
- By:
- Publication type:
- Article
1808-P: Hepatocyte Traf Family Members Link Inflammation to Liver Steatosis and Insulin Resistance.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1808-P
- By:
- Publication type:
- Article
1760-P: Brain Sh2b1 Protects against Obesity and Insulin Resistance through Multiple Hypothalamic Neural Circuits.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1760-P
- By:
- Publication type:
- Article
211-OR: Hypothalamic Slug Couples Overnutrition States to Epigenetic Reprogramming of Leptin Neural Circuits, Obesity, and Type 2 Diabetes.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-211-OR
- By:
- Publication type:
- Article
1964-P: Slug Epigenetically Represses Adipose Thermogenic Programs.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1964-P
- By:
- Publication type:
- Article
SH2B1 in β-Cells Regulates Glucose Metabolism by Promoting β-Cell Survival and Islet Expansion.
- Published in:
- Diabetes, 2014, v. 63, n. 2, p. 585, doi. 10.2337/db13-0666
- By:
- Publication type:
- Article
Hepatic TRAF2 Regulates Glucose Metabolism Through Enhancing Glucagon Responses.
- Published in:
- Diabetes, 2012, v. 61, n. 3, p. 566, doi. 10.2337/db11-0474
- By:
- Publication type:
- Article
SH2B 1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins.
- Published in:
- Diabetes, 2009, v. 58, n. 9, p. 2039, doi. 10.2337/db08-1388
- By:
- Publication type:
- Article
SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins.
- Published in:
- 2009
- By:
- Publication type:
- journal article