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CaMKIIβ deregulation contributes to neuromuscular junction destabilization in Myotonic Dystrophy type I.
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- Skeletal Muscle, 2024, v. 14, n. 1, p. 1, doi. 10.1186/s13395-024-00345-3
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- Article
Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41769-7
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- Article
Dual roles of mTORC1-dependent activation of the ubiquitin-proteasome system in muscle proteostasis.
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04097-y
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- Article
Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29714-6
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- Publication type:
- Article
Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29714-6
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- Article
Author Correction: Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29714-6
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- Publication type:
- Article
Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia.
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- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-01723-z
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- Article
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia.
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- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18140-1
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- Article
The TOR Pathway at the Neuromuscular Junction: More Than a Metabolic Player?
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- Frontiers in Molecular Neuroscience, 2020, v. 13, p. N.PAG, doi. 10.3389/fnmol.2020.00162
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- Article
Mice carrying an analogous heterozygous dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy.
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- Human Molecular Genetics, 2020, v. 29, n. 8, p. 1253, doi. 10.1093/hmg/ddaa034
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- Article
mTORC1 signalling is not essential for the maintenance of muscle mass and function in adult sedentary mice.
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- Journal of Cachexia, Sarcopenia & Muscle, 2020, v. 11, n. 1, p. 259, doi. 10.1002/jcsm.12505
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- Article
mTORC2 affects the maintenance of the muscle stem cell pool.
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- Skeletal Muscle, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1186/s13395-019-0217-y
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- Publication type:
- Article
Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA.
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- Nucleic Acids Research, 2019, v. 47, n. 14, p. 7618, doi. 10.1093/nar/gkz469
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- Article
mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11227-4
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- Article
Collagen XIII Is Required for Neuromuscular Synapse Regeneration and Functional Recovery after Peripheral Nerve Injury.
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- Journal of Neuroscience, 2018, v. 38, n. 17, p. 4243, doi. 10.1523/JNEUROSCI.3119-17.2018
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- Article
Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.
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- 2017
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- Publication type:
- journal article
Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing.
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- Nature Communications, 2017, v. 8, n. 7, p. 16014, doi. 10.1038/ncomms16014
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- Article
Linker proteins restore basement membrane and correct LAMA2-related muscular dystrophy in mice.
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- Science Translational Medicine, 2017, v. 9, n. 396, p. 1, doi. 10.1126/scitranslmed.aal4649
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- Article
Chimeric protein repair of laminin polymerization ameliorates muscular dystrophy phenotype.
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- 2017
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- Publication type:
- journal article
Targeting deregulated AMPK/mTORC1 pathways improves muscle function in myotonic dystrophy type I.
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- 2017
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- Publication type:
- journal article
mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation.
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- Nature Communications, 2016, v. 7, n. 10, p. 13226, doi. 10.1038/ncomms13226
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- Article
Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism.
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- Skeletal Muscle, 2016, v. 6, p. 1, doi. 10.1186/s13395-016-0084-8
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- Publication type:
- Article
Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.
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- Cardiovascular Research, 2016, v. 109, n. 1, p. 103, doi. 10.1093/cvr/cvv252
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- Publication type:
- Article
Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult.
- Published in:
- Scientific Reports, 2015, v. 5, n. 1, p. 17705, doi. 10.1038/srep17705
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- Article
Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.
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- Science Signaling, 2015, v. 8, n. 402, p. 1, doi. 10.1126/scisignal.aab3715
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- Article
m TORC1 and m TORC2 have largely distinct functions in Purkinje cells.
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- European Journal of Neuroscience, 2015, v. 42, n. 8, p. 2595, doi. 10.1111/ejn.13051
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- Article
Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
- Published in:
- Carcinogenesis, 2015, v. 36, n. 4, p. 487, doi. 10.1093/carcin/bgv012
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- Article
Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice.
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- Journal of Clinical Investigation, 2015, v. 125, n. 4, p. 1446, doi. 10.1172/JCI79766
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- Article
Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex.
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- Biochemical Journal, 2015, v. 466, n. 1, p. 123, doi. 10.1042/BJ20140935
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- Article
Differential regulation of AChR clustering in the polar and equatorial region of murine muscle spindles.
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- European Journal of Neuroscience, 2015, v. 41, n. 1, p. 69, doi. 10.1111/ejn.12768
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- Article
The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions.
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- Cell & Tissue Research, 2014, v. 358, n. 2, p. 465, doi. 10.1007/s00441-014-1969-7
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- Article
Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination.
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- Journal of Neuroscience, 2014, v. 34, n. 25, p. 8432, doi. 10.1523/JNEUROSCI.1105-14.2014
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- Article
Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.
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- Journal of Molecular Cell Biology, 2014, v. 6, n. 3, p. 255, doi. 10.1093/jmcb/mju008
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- Article
WNT7B Promotes Bone Formation in part through mTORC1.
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- PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1004145
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- Article
Inactivation of mTORCl in the Developing Brain Causes Microcephaly and Affects Gliogenesis.
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- Journal of Neuroscience, 2013, v. 33, n. 18, p. 7799, doi. 10.1523/JNEUROSCI.3294-12.2013
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- Article
Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy.
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- Skeletal Muscle, 2013, v. 3, n. 1, p. 1, doi. 10.1186/2044-5040-3-6
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- Publication type:
- Article
Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation.
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- Glia, 2012, v. 60, n. 11, p. 1646, doi. 10.1002/glia.22383
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- Article
Fatigue and Muscle Atrophy in a Mouse Model of Myasthenia Gravis Is Paralleled by Loss of Sarcolemmal nNOS.
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- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0044148
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- Article
Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice.
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- EMBO Molecular Medicine, 2011, v. 3, n. 8, p. 465, doi. 10.1002/emmm.201100151
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- Article
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
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- 2011
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- Publication type:
- journal article
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
- Published in:
- 2011
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- Publication type:
- journal article
MuSK levels differ between adult skeletal muscles and influence postsynaptic plasticity.
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- European Journal of Neuroscience, 2011, v. 33, n. 5, p. 890, doi. 10.1111/j.1460-9568.2010.07569.x
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- Publication type:
- Article
Sec24- and ARFGAP1-Dependent Trafficking of GABA Transporter-1 Is a Prerequisite for Correct Axonal Targeting.
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- Journal of Neuroscience, 2008, v. 28, n. 47, p. 12453, doi. 10.1523/JNEUROSCI.3451-08.2008
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- Publication type:
- Article
Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells.
- Published in:
- Nature Neuroscience, 2007, v. 10, n. 6, p. 712, doi. 10.1038/nn1897
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- Article
Tyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors.
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- BMC Neuroscience, 2007, v. 8, p. 46, doi. 10.1186/1471-2202-8-46
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- Publication type:
- Article
Src-Family Kinases Stabilize the Neuromuscular Synapse In Vivo via Protein Interactions, Phosphorylation, and Cytoskeletal Linkage of Acetylcholine Receptors.
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- Journal of Neuroscience, 2005, v. 25, n. 45, p. 10479, doi. 10.1523/JNEUROSCI.2103-05.2005
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- Article
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
- Published in:
- Nature Cell Biology, 2004, v. 6, n. 11, p. 1122, doi. 10.1038/ncb1183
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- Publication type:
- Article
Mapping of the laminin-binding site of the N-terminal agrin domain (NtA).
- Published in:
- EMBO Journal, 2003, v. 22, n. 3, p. 529, doi. 10.1093/emboj/cdg041
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- Publication type:
- Article
The laminin-binding domain of agrin is structurally related to N-TIMP-1.
- Published in:
- Nature Structural Biology, 2001, v. 8, n. 8, p. 705, doi. 10.1038/90422
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- Publication type:
- Article