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Characterization of the chronic myelomonocytic leukemia associated TEL-PDGFβR fusion protein.
- Published in:
- Oncogene, 1999, v. 18, n. 50, p. 7055, doi. 10.1038/sj.onc.1203190
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- Publication type:
- Article
Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction.
- Published in:
- Oncogene, 1999, v. 18, n. 40, p. 5546, doi. 10.1038/sj.onc.1202929
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- Publication type:
- Article
SHP-2 binds to Tyr763 and Tyr1009 in the PDGF β-receptor and mediates PDGF-induced activation of the Ras/MAP kinase pathway and chemotaxis.
- Published in:
- Oncogene, 1999, v. 18, n. 25, p. 3696, doi. 10.1038/sj.onc.1202705
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- Publication type:
- Article
Increased mitogenicity of an αβ heterodimeric PDGF receptor complex correlates with lack of RasGAP binding.
- Published in:
- Oncogene, 1999, v. 18, n. 15, p. 2481, doi. 10.1038/sj.onc.1202606
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- Publication type:
- Article
Identification of Tyr-762 in the platelet-derived growth factor α-receptor as the binding site for Crk proteins.
- Published in:
- Oncogene, 1998, v. 16, n. 10, p. 1229, doi. 10.1038/sj.onc.1201641
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- Publication type:
- Article
Mechanisms of platelet-derived growth factor-induced chemotaxis.
- Published in:
- International Journal of Cancer, 2001, v. 91, n. 6, p. 757, doi. 10.1002/1097-0215(200002)9999:9999<::AID-IJC1136>3.0.CO;2-J
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- Publication type:
- Article
PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner.
- Published in:
- Cellular & Molecular Life Sciences, 2015, v. 72, n. 22, p. 4399, doi. 10.1007/s00018-015-1944-9
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- Publication type:
- Article
Role of SRC-like adaptor protein (SLAP) in immune and malignant cell signaling.
- Published in:
- Cellular & Molecular Life Sciences, 2015, v. 72, n. 13, p. 2535, doi. 10.1007/s00018-015-1882-6
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- Publication type:
- Article
SOCS proteins in regulation of receptor tyrosine kinase signaling.
- Published in:
- Cellular & Molecular Life Sciences, 2014, v. 71, n. 17, p. 3297, doi. 10.1007/s00018-014-1619-y
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- Publication type:
- Article
A Receptor Tyrosine Kinase Inhibitor Sensitivity Prediction Model Identifies AXL Dependency in Leukemia.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3830, doi. 10.3390/ijms24043830
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- Publication type:
- Article
Correction: The ALK inhibitor AZD3463 effectively inhibits growth of sorafenib-resistant acute myeloid leukemia.
- Published in:
- 2019
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- Correction Notice
De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04180-1
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- Publication type:
- Article
Metallopeptidase inhibitor 1 (TIMP‐1) promotes receptor tyrosine kinase c‐Kit signaling in colorectal cancer.
- Published in:
- Molecular Oncology, 2019, v. 13, n. 12, p. 2646, doi. 10.1002/1878-0261.12575
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- Publication type:
- Article
Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling.
- Published in:
- Molecular Oncology, 2013, v. 7, n. 3, p. 693, doi. 10.1016/j.molonc.2013.02.020
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- Publication type:
- Article
FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia.
- Published in:
- Molecular Oncology, 2013, v. 7, n. 3, p. 402, doi. 10.1016/j.molonc.2012.11.003
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- Publication type:
- Article
Irreversible pan-ERBB inhibitor canertinib elicits anti-leukaemic effects and induces the regression of FLT3-ITD transformed cells in mice.
- Published in:
- British Journal of Haematology, 2011, v. 155, n. 2, p. 198, doi. 10.1111/j.1365-2141.2011.08819.x
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- Publication type:
- Article
A role of Gab2 association in Flt3 ITD mediated Stat5 phosphorylation and cell survival.
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- British Journal of Haematology, 2009, v. 146, n. 2, p. 193, doi. 10.1111/j.1365-2141.2009.07725.x
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- Publication type:
- Article
Haematopoietic progenitor cells utilise conventional PKC to suppress PKB/Akt activity in response to c-Kit stimulation.
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- British Journal of Haematology, 2007, v. 136, n. 2, p. 260, doi. 10.1111/j.1365-2141.2006.06434.x
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- Publication type:
- Article
Src-Like Adaptor Protein (SLAP) Binds to the Receptor Tyrosine Kinase Flt3 and Modulates Receptor Stability and Downstream Signaling.
- Published in:
- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0053509
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- Publication type:
- Article
C-KIT Signaling Depends on Microphthalmia-Associated Transcription Factor for Effects on Cell Proliferation.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0024064
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- Publication type:
- Article
Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD.
- Published in:
- Cellular & Molecular Life Sciences, 2017, v. 74, n. 14, p. 2679, doi. 10.1007/s00018-017-2494-0
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- Publication type:
- Article
Phosphorylation-dependent and -independent functions of p130 cooperate to evoke a sustained G<sub>1</sub> block.
- Published in:
- EMBO Journal, 2001, v. 20, n. 3, p. 422, doi. 10.1093/emboj/20.3.422
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- Publication type:
- Article
Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia.
- Published in:
- Medical Oncology, 2013, v. 30, n. 4, p. 1, doi. 10.1007/s12032-013-0757-7
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- Publication type:
- Article
The basic helix-loop-helix (bHLH) proteins in breast cancer progression.
- Published in:
- 2013
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- Publication type:
- Letter
Enhanced SOX10 and KIT expression in cutaneous melanoma.
- Published in:
- 2013
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- Publication type:
- Letter
Deregulation of protein phosphatase expression in acute myeloid leukemia.
- Published in:
- Medical Oncology, 2013, v. 30, n. 2, p. 1, doi. 10.1007/s12032-013-0517-8
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- Publication type:
- Article
FLT3 mutations in patients with childhood acute lymphoblastic leukemia (ALL).
- Published in:
- 2013
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- Publication type:
- Letter
Platelet-derived growth factor receptors in the kidney--Upregulated expression in inflammation.
- Published in:
- Kidney International, 1989, v. 36, n. 6, p. 1099, doi. 10.1038/ki.1989.306
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- Publication type:
- Article
Interaction and functional cooperation between the serine/threonine kinase bone morphogenetic protein type II receptor with the tyrosine kinase stem cell factor receptor<FNR></FNR><FN>This article includes Supplementary Material available from the authors upon request or via the Internet at <URL>http://www.interscience.wiley.com/jpages/0021-9541/suppmat</URL>. </FN>
- Published in:
- Journal of Cellular Physiology, 2006, v. 206, n. 2, p. 457, doi. 10.1002/jcp.20480
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- Publication type:
- Article
Understanding the Role of Activation Loop Mutants in Drug Efficacy for FLT3-ITD.
- Published in:
- Cancers, 2023, v. 15, n. 22, p. 5426, doi. 10.3390/cancers15225426
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- Publication type:
- Article
Keratin 19 expression correlates with poor prognosis in breast cancer.
- Published in:
- Molecular Biology Reports, 2014, v. 41, n. 12, p. 7729, doi. 10.1007/s11033-014-3684-6
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- Publication type:
- Article
Internal tandem duplication mutations in the tyrosine kinase domain of FLT3 display a higher oncogenic potential than the activation loop D835Y mutation.
- Published in:
- Annals of Hematology, 2018, v. 97, n. 5, p. 773, doi. 10.1007/s00277-018-3245-5
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- Publication type:
- Article
3,4-Diarylmaleimides-a novel class of kinase inhibitors-effectively induce apoptosis in FLT3-ITD-dependent cells.
- Published in:
- Annals of Hematology, 2012, v. 91, n. 3, p. 331, doi. 10.1007/s00277-011-1311-3
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- Publication type:
- Article
Xputer: bridging data gaps with NMF, XGBoost, and a streamlined GUI experience.
- Published in:
- Frontiers in Artificial Intelligence, 2024, p. 01, doi. 10.3389/frai.2024.1345179
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- Publication type:
- Article
Ezrin is a substrate for Lck in T cells
- Published in:
- FEBS Letters, 2003, v. 535, n. 1-3, p. 82, doi. 10.1016/S0014-5793(02)03861-9
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- Publication type:
- Article