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Purinergic Ca 2+ Signaling as a Novel Mechanism of Drug Tolerance in BRAF-Mutant Melanoma.
- Published in:
- Cancers, 2024, v. 16, n. 13, p. 2426, doi. 10.3390/cancers16132426
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- Article
Unified tumor growth mechanisms from multimodel inference and dataset integration.
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- PLoS Computational Biology, 2023, v. 19, n. 7, p. 1, doi. 10.1371/journal.pcbi.1011215
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- Article
Involvement of Epithelial–Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity.
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- Cancers, 2023, v. 15, n. 5, p. 1477, doi. 10.3390/cancers15051477
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- Publication type:
- Article
MuSyC dosing of adjuvanted cancer vaccines optimizes antitumor responses.
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- Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.936129
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- Publication type:
- Article
Organoids as a Systems Platform for SCLC Brain Metastasis.
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- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.881989
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- Publication type:
- Article
MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24789-z
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- Publication type:
- Article
Thunor: visualization and analysis of high-throughput dose–response datasets.
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- Nucleic Acids Research, 2021, v. 49, n. W1, p. W633, doi. 10.1093/nar/gkab424
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- Article
An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability.
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- PLoS Biology, 2021, v. 19, n. 6, p. 1, doi. 10.1371/journal.pbio.3000797
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- Article
ACDC: Automated Cell Detection and Counting for Time-Lapse Fluorescence Microscopy.
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- Applied Sciences (2076-3417), 2020, v. 10, n. 18, p. 6187, doi. 10.3390/app10186187
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- Publication type:
- Article
Drug-Tolerant Idling Melanoma Cells Exhibit Theory-Predicted Metabolic Low-Low Phenotype.
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- Frontiers in Oncology, 2020, v. 10, p. N.PAG, doi. 10.3389/fonc.2020.01426
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- Publication type:
- Article
Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers.
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- PLoS Computational Biology, 2019, v. 15, n. 10, p. 1, doi. 10.1371/journal.pcbi.1007343
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- Publication type:
- Article
Dynamics of drug response informs rational combination regimens.
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- Science Signaling, 2019, v. 12, n. 595, p. 1, doi. 10.1126/scisignal.aax9742
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- Publication type:
- Article
Leveraging Mathematical Modeling to Quantify Pharmacokinetic and Pharmacodynamic Pathways: Equivalent Dose Metric.
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- Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00616
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- Publication type:
- Article
Ventricular-Subventricular Zone Contact by Glioblastoma is Not Associated with Molecular Signatures in Bulk Tumor Data.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37734-w
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- Publication type:
- Article
Variable Cell Line Pharmacokinetics Contribute to Non-Linear Treatment Response in Heterogeneous Cell Populations.
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- Annals of Biomedical Engineering, 2018, v. 46, n. 6, p. 899, doi. 10.1007/s10439-018-2001-2
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- Publication type:
- Article
A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase.
- Published in:
- PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0192087
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- Publication type:
- Article
Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition.
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- Scientific Reports, 2017, p. 42604, doi. 10.1038/srep42604
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- Publication type:
- Article
Altered TGF-α/β signaling drives cooperation between breast cancer cell populations.
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- FASEB Journal, 2016, v. 30, n. 10, p. 3441, doi. 10.1096/fj.201500187RR
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- Publication type:
- Article
Quantifying heterogeneity and dynamics of clonal fitness in response to perturbation.
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- Journal of Cellular Physiology, 2015, v. 230, n. 7, p. 1403, doi. 10.1002/jcp.24888
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- Publication type:
- Article
Automated Analysis of Cell-Matrix Adhesions in 2D and 3D Environments.
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- Scientific Reports, 2015, p. 8124, doi. 10.1038/srep08124
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- Publication type:
- Article
Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer.
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- BMC Systems Biology, 2013, v. 7, p. 1, doi. 10.1186/1752-0509-7-S5-S1
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- Publication type:
- Article
What Lies Beneath: Looking Beyond Tumor Genetics Shows the Complexity of Signaling Networks Underlying Drug Sensitivity.
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- Science Signaling, 2013, v. 6, n. 294, p. 1, doi. 10.1126/scisignal.2004715
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- Publication type:
- Article
Clinically Relevant Modeling of Tumor Growth and Treatment Response.
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- Science Translational Medicine, 2013, v. 5, n. 187, p. 1, doi. 10.1126/scitranslmed.3005686
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- Publication type:
- Article
Network Analysis of the Focal Adhesion to Invadopodia Transition Identifies a PI3K-PKCα Invasive Signaling Axis.
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- Science Signaling, 2012, v. 5, n. 241, p. 1, doi. 10.1126/scisignal.2002964
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- Publication type:
- Article
Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data.
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- Nature Methods, 2012, v. 9, n. 9, p. 923, doi. 10.1038/nmeth.2138
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- Publication type:
- Article
Establishment and Validation of Computational Model for MT1-MMP Dependent ECM Degradation and Intervention Strategies.
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- PLoS Computational Biology, 2012, v. 8, n. 4, p. 1, doi. 10.1371/journal.pcbi.1002479
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- Publication type:
- Article
Computational investigation of intrinsic and extrinsic mechanisms underlying the formation of carcinoma.
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- Mathematical Medicine & Biology: A Journal of the IMA, 2012, v. 29, n. 1, p. 67, doi. 10.1093/imammb/dqq021
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- Article
CellAnimation: an open source MATLAB framework for microscopy assays.
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- Bioinformatics, 2012, v. 28, n. 1, p. 138, doi. 10.1093/bioinformatics/btr633
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- Publication type:
- Article
Development of high-throughput quantitative assays for glucose uptake in cancer cell lines.
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- 2011
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- Publication type:
- journal article
Influence of cell cycle phase on apparent diffusion coefficient in synchronized cells detected using temporal diffusion spectroscopy.
- Published in:
- Magnetic Resonance in Medicine, 2011, v. 65, n. 4, p. 920, doi. 10.1002/mrm.22704
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- Publication type:
- Article
Laminin-332 cleavage by matriptase alters motility parameters of prostate cancer cells.
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- Prostate, 2011, v. 71, n. 2, p. 184, doi. 10.1002/pros.21233
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- Article
Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling.
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- PLoS Computational Biology, 2010, v. 6, n. 8, p. 1, doi. 10.1371/journal.pcbi.1000900
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- Publication type:
- Article
Epitope mapping of function-blocking monoclonal antibody CM6 suggests a “weak” integrin binding site on the laminin-332 LG2 domain.
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- Journal of Cellular Physiology, 2010, v. 223, n. 3, p. 541, doi. 10.1002/jcp.22107
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- Publication type:
- Article
Laminin-332–β1 integrin interactions negatively regulate invadopodia.
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- Journal of Cellular Physiology, 2010, v. 223, n. 1, p. 134, doi. 10.1002/jcp.22018
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- Publication type:
- Article
Not all noise is waste.
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- Nature Methods, 2010, v. 7, n. 4, p. 269, doi. 10.1038/nmeth0410-269
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- Publication type:
- Article
Human Mammary Epithelial Cells Exhibit a Bimodal Correlated Random Walk Pattern.
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- PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009636
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- Publication type:
- Article
Lysophosphatidic Acid Upregulates Laminin-332 Expression during A431 Cell Colony Dispersal.
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- Journal of Oncology, 2010, p. 1, doi. 10.1155/2010/107075
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- Publication type:
- Article
Microenvironment driven invasion: a multiscale multimodel investigation.
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- Journal of Mathematical Biology, 2009, v. 58, n. 4/5, p. 579, doi. 10.1007/s00285-008-0210-2
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- Publication type:
- Article
Cadherin-Bound β-Catenin Feeds into the Wnt Pathway upon Adherens Junctions Dissociation: Evidence for an Intersection betweenβ -Catenin Pools.
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- PLoS ONE, 2009, v. 4, n. 2, p. 1, doi. 10.1371/journal.pone.0004580
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- Publication type:
- Article
Integrative mathematical oncology.
- Published in:
- 2008
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- Publication type:
- review
A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro.
- Published in:
- BMC Cancer, 2008, v. 8, p. 1, doi. 10.1186/1471-2407-8-198
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- Publication type:
- Article
Modeling of Effects of Nutrient Gradients on Cell Proliferation in Microfluidic Bioreactor.
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- Biotechnology Progress, 2007, v. 23, n. 6, p. 1347
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- Publication type:
- Article
Biological Scales.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A97
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- Publication type:
- Article
Binding of Integrins to Laminins.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A152
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- Publication type:
- Article
Dispersal of epithelial cancer cell colonies by lysophosphatidic acid (LPA)<FNR></FNR><FN>Jérôme Jourquin and Neng Yang are equal first authors. </FN>.
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- Journal of Cellular Physiology, 2006, v. 206, n. 2, p. 337, doi. 10.1002/jcp.20470
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- Publication type:
- Article
Tumor cell &alpha<sub>3</sub>;β<sub>1</sub> integrin and vascular laminin-5 mediate pulmonary arrest and metastasis.
- Published in:
- Journal of Cell Biology, 2004, v. 164, n. 6, p. 935, doi. 10.1083/jcb.200309112
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- Publication type:
- Article
Proteolytic processing of laminin-5 by MT1-MMP in tissues and its effects on epithelial cell morphology.
- Published in:
- FASEB Journal, 2004, v. 18, n. 2, p. 364, doi. 10.1096/fj.03-0584fje
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- Publication type:
- Article
Remodeling of the Microenvironment by Aggressive Melanoma Tumor Cells.
- Published in:
- Annals of the New York Academy of Sciences, 2003, v. 995, n. 1, p. 151, doi. 10.1111/j.1749-6632.2003.tb03218.x
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- Publication type:
- Article
Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution.
- Published in:
- Journal of Cell Biology, 2003, v. 161, n. 1, p. 197, doi. 10.1083/jcb.200208145
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- Publication type:
- Article
Inhibitory Role of alpha 6 beta 4-associated erbB-2 and Phosphoinositide 3-Kinase in Keratinocyte...
- Published in:
- Journal of Cell Biology, 2001, v. 153, n. 3, p. 465, doi. 10.1083/jcb.153.3.465
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- Publication type:
- Article