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Reengineering a transmembrane protein to treat muscular dystrophy using exon skipping.
Published in:
2015
By:
- Quan Q. Gao;
- Wyatt, Eugene;
- Goldstein, Jeff A.;
- LoPresti, Peter;
- Castillo, Lisa M.;
- Gazda, Alec;
- Petrossian, Natalie;
- Earley, Judy U.;
- Hadhazy, Michele;
- Barefield, David Y.;
- Demonbreun, Alexis R.;
- Bönnemann, Carsten;
- Wolf, Matthew;
- McNally, Elizabeth M.;
- Gao, Quan Q
Publication type:
journal article
Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.29702
By:
- Putzbach, William;
- Quan Q. Gao;
- Patel, Monal;
- van Dongen, Stijn;
- Haluck-Kangas, Ashley;
- Sarshad, Aishe A.;
- Bartom, Elizabeth T.;
- Kwang-Youn A. Kim;
- Scholtens, Denise M.;
- Hafner, Markus;
- Zhao, Jonathan C.;
- Murmann, Andrea E.;
- Peter, Marcus E.
Publication type:
Article
Thrombospondin expression in myofibers stabilizes muscle membranes.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.17589
By:
- Vanhoutte, Davy;
- Schips, Tobias G.;
- Kwong, Jennifer Q.;
- Davis, Jennifer;
- Tjondrokoesoemo, Andoria;
- Brody, Matthew J.;
- Sargent, Michelle A.;
- Kanisicak, Onur;
- Hong Yi;
- Gao, Quan Q.;
- Rabinowitz, Joseph E.;
- Volk, Talila;
- McNally, Elizabeth M.;
- Molkentin, Jeffery D.
Publication type:
Article
Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells.
Published in:
EMBO Reports, 2018, v. 19, n. 3, p. 1, doi. 10.15252/embr.201745336
By:
- Murmann, Andrea E.;
- Gao, Quan Q.;
- Putzbach, William E.;
- Patel, Monal;
- Bartom, Elizabeth T.;
- Law, Calvin Y.;
- Bridgeman, Bryan;
- Chen, Siquan;
- McMahon, Kaylin M.;
- Thaxton, C. Shad;
- Peter, Marcus E.
Publication type:
Article
6mer seed toxicity in tumor suppressive microRNAs.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06526-1
By:
- Gao, Quan Q.;
- Putzbach, William E.;
- Murmann, Andrea E.;
- Siquan Chen;
- Sarshad, Aishe A.;
- Peter, Johannes M.;
- Bartom, Elizabeth T.;
- Hafner, Markus;
- Peter, Marcus E.
Publication type:
Article
Dusp6 is a genetic modifier of growth through enhanced ERK activity.
Published in:
Human Molecular Genetics, 2019, v. 28, n. 2, p. 279, doi. 10.1093/hmg/ddy349
By:
- Vo, Andy H;
- Swaggart, Kayleigh A;
- Woo, Anna;
- Gao, Quan Q;
- Demonbreun, Alexis R;
- Fallon, Katherine S;
- Quattrocelli, Mattia;
- Hadhazy, Michele;
- Page, Patrick G T;
- Chen, Zugen;
- Eskin, Ascia;
- Squire, Kevin;
- Nelson, Stanley F;
- McNally, Elizabeth M
Publication type:
Article
Excess SMAD signaling contributes to heart and muscle dysfunction in muscular dystrophy.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 25, p. 6722, doi. 10.1093/hmg/ddu390
By:
- Goldstein, Jeffery A.;
- Bogdanovich, Sasha;
- Beiriger, Anastasia;
- Wren, Lisa M.;
- Rossi, Ann E.;
- Gao, Quan Q.;
- Gardner, Brandon B.;
- Earley, Judy U.;
- Molkentin, Jeffery D.;
- McNally, Elizabeth M.
Publication type:
Article
Excess SMAD signaling contributes to heart and muscle dysfunction in muscular dystrophy.
Published in:
Human Molecular Genetics, 2012, v. 21, n. 25, p. 1, doi. 10.1093/hmg/ddu390
By:
- Goldstein, Jeffery A.;
- Bogdanovich, Sasha;
- Beiriger, Anastasia;
- Wren, Lisa M.;
- Rossi, Ann E.;
- Gao, Quan Q.;
- Gardner, Brandon B.;
- Earley, Judy U.;
- Molkentin, Jeffery D.;
- McNally, Elizabeth M.
Publication type:
Article
Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ.
Published in:
PLoS Genetics, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pgen.1006019
By:
- Lamar, Kay-Marie;
- Bogdanovich, Sasha;
- Gardner, Brandon B.;
- Gao, Quan Q.;
- Miller, Tamari;
- Earley, Judy U.;
- Hadhazy, Michele;
- Vo, Andy H.;
- Wren, Lisa;
- Molkentin, Jeffery D.;
- McNally, Elizabeth M.
Publication type:
Article

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