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Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair.
- Published in:
- eLife, 2018, p. 1, doi. 10.7554/eLife.32692
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- Article
The role of the Pseudomonas aeruginosa hypermutator phenotype on the shift from acute to chronic virulence during respiratory infection.
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- Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.943346
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- Article
The high fidelity and unique error signature of human DNA polymerase ϵ.
- Published in:
- Nucleic Acids Research, 2011, v. 39, n. 5, p. 1763, doi. 10.1093/nar/gkq1034
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- Article
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase γ replication fidelity.
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- Nucleic Acids Research, 2008, v. 36, n. 7, p. 2174, doi. 10.1093/nar/gkn062
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- Article
Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase ε.
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- Nucleic Acids Research, 2007, v. 35, n. 9, p. 3076, doi. 10.1093/nar/gkm132
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- Article
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.
- Published in:
- Nature Genetics, 2015, v. 47, n. 3, p. 257, doi. 10.1038/ng.3202
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- Article
Replication DNA polymerases, genome instability and cancer therapies.
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- NAR Cancer, 2023, v. 5, n. 3, p. 1, doi. 10.1093/narcan/zcad033
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- Article
Mouse model and human patient data reveal critical roles for Pten and p53 in suppressing POLE mutant tumor development.
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- NAR Cancer, 2022, v. 4, n. 1, p. 1, doi. 10.1093/narcan/zcac004
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- Article
Light-strand bias and enriched zones of embedded ribonucleotides are associated with DNA replication and transcription in the human-mitochondrial genome.
- Published in:
- Nucleic Acids Research, 2024, v. 52, n. 3, p. 1207, doi. 10.1093/nar/gkad1204
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- Article
Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity.
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- PLoS Genetics, 2012, v. 8, n. 10, p. 1, doi. 10.1371/journal.pgen.1003016
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- Article
RNA-mediated double-strand break repair by end-joining mechanisms.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51457-9
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- Article
DNA polymerase ε and its roles in genome stability.
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- IUBMB Life, 2014, v. 66, n. 5, p. 339, doi. 10.1002/iub.1276
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- Article