Works by Pursell, Zachary F

Results: 13

RNA-mediated double-strand break repair by end-joining mechanisms.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51457-9

By:

Jeon, Youngkyu;
Lu, Yilin;
Ferrari, Margherita Maria;
Channagiri, Tejasvi;
Xu, Penghao;
Meers, Chance;
Zhang, Yiqi;
Balachander, Sathya;
Park, Vivian S.;
Marsili, Stefania;
Pursell, Zachary F.;
Jonoska, Nataša;
Storici, Francesca

Publication type:

Article

The high fidelity and unique error signature of human DNA polymerase ϵ.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 5, p. 1763, doi. 10.1093/nar/gkq1034

By:

Korona, Dagmara A.;
LeCompte, Kimberly G.;
Pursell, Zachary F.

Publication type:

Article

Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase γ replication fidelity.

Published in:

Nucleic Acids Research, 2008, v. 36, n. 7, p. 2174, doi. 10.1093/nar/gkn062

By:

Pursell, Zachary F.;
McDonald, J. Tyson;
Mathews, Christopher K.;
Kunkel, Thomas A.

Publication type:

Article

Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase ε.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 9, p. 3076, doi. 10.1093/nar/gkm132

By:

Pursell, Zachary F.;
Isoz, Isabelle;
Lundström, Else-Britt;
Johansson, Erik;
Kunkel, Thomas A.

Publication type:

Article

Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity.

Published in:

PLoS Genetics, 2012, v. 8, n. 10, p. 1, doi. 10.1371/journal.pgen.1003016

By:

Lujan, Scott A.;
Williams, Jessica S.;
Pursell, Zachary F.;
Abdulovic-Cui, Amy A.;
Clark, Alan B.;
McElhinny, Stephanie A. Nick;
Kunkel, Thomas A.

Publication type:

Article

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

Published in:

Nature Genetics, 2015, v. 47, n. 3, p. 257, doi. 10.1038/ng.3202

By:

Shlien, Adam;
Meier, Bettina;
Hong, Ye;
Gartner, Anton;
Remke, Marc;
Thakkar, Neha P;
Pearson, Christopher E;
Hodel, Karl P;
Henninger, Erin E;
Göksenin, A Yasemin;
Pursell, Zachary F;
Bakry, Doua;
Grant, Ronald;
Nathan, Paul C;
Alexander, Sarah;
Charames, George S;
Druker, Harriet;
Lerner-Ellis, Jordan;
Dvir, Rina;
Elhasid, Ronit

Publication type:

Article

Altered dNTP pools accelerate tumor formation in mice.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 20, p. 12475, doi. 10.1093/nar/gkae843

By:

Tran, Phong;
Mishra, Pradeep;
Williams, Leonard G;
Moskalenko, Roman;
Sharma, Sushma;
Nilsson, Anna Karin;
Watt, Danielle L;
Andersson, Pernilla;
Bergh, Anders;
Pursell, Zachary F;
Chabes, Andrei

Publication type:

Article

Light-strand bias and enriched zones of embedded ribonucleotides are associated with DNA replication and transcription in the human-mitochondrial genome.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 3, p. 1207, doi. 10.1093/nar/gkad1204

By:

Xu, Penghao;
Yang, Taehwan;
Kundnani, Deepali L;
Sun, Mo;
Marsili, Stefania;
Gombolay, Alli L;
Jeon, Youngkyu;
Newnam, Gary;
Balachander, Sathya;
Bazzani, Veronica;
Baccarani, Umberto;
Park, Vivian S;
Tao, Sijia;
Lori, Adriana;
Schinazi, Raymond F;
Kim, Baek;
Pursell, Zachary F;
Tell, Gianluca;
Vascotto, Carlo;
Storici, Francesca

Publication type:

Article

DNA polymerase ε and its roles in genome stability.

Published in:

IUBMB Life, 2014, v. 66, n. 5, p. 339, doi. 10.1002/iub.1276

By:

Henninger, Erin E.;
Pursell, Zachary F.

Publication type:

Article

Replication DNA polymerases, genome instability and cancer therapies.

Published in:

NAR Cancer, 2023, v. 5, n. 3, p. 1, doi. 10.1093/narcan/zcad033

By:

Strauss, Juliet D.;
Pursell, Zachary F.

Publication type:

Article

Mouse model and human patient data reveal critical roles for Pten and p53 in suppressing POLE mutant tumor development.

Published in:

NAR Cancer, 2022, v. 4, n. 1, p. 1, doi. 10.1093/narcan/zcac004

By:

Park, Vivian S.;
Sun, Meijuan J. S.;
Frey, Wesley D.;
Williams, Leonard G.;
Hodel, Karl P.;
Strauss, Juliet D.;
Wellens, Sydney J.;
Jackson, James G.;
Pursell, Zachary F.

Publication type:

Article

Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair.

Published in:

eLife, 2018, p. 1, doi. 10.7554/eLife.32692

By:

Hodel, Karl P.;
de Borja, Richard;
Henninger, Erin E.;
Campbell, Brittany B.;
Ungerleider, Nathan;
Light, Nicholas;
Tong Wu;
LeCompte, Kimberly G.;
Goksenin, A. Yasemin;
Bunnell, Bruce A.;
Tabori, Uri;
Shlien, Adam;
Pursell, Zachary F.

Publication type:

Article

The role of the Pseudomonas aeruginosa hypermutator phenotype on the shift from acute to chronic virulence during respiratory infection.

Published in:

Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.943346

By:

Hall, Kalen M.;
Pursell, Zachary F.;
Morici, Lisa A.

Publication type:

Article