Works by Pumin Zhang

Results: 54

Inhibitory Phosphorylation of Separase Is Essential for Genome Stability and Viability of Murine Embryonic Germ Cells.

Published in:

PLoS Biology, 2008, v. 6, n. 1, p. e15, doi. 10.1371/journal.pbio.0060015

By:

Xingxu Huang;
Andreu-Vieyra, Claudia V.;
York, J. Philippe;
Hatcher, Rashieda;
Tao Lu;
Matzuk, Martin M.;
Pumin Zhang

Publication type:

Article

The anaphase promoting complex promotes NHEJ repair through stabilizing Ku80 at DNA damage sites.

Published in:

Cell Cycle, 2018, v. 17, n. 9, p. 1138, doi. 10.1080/15384101.2018.1464836

By:

Ma, Chengxian;
Ha, Kyungsoo;
Kim, Min-su;
Noh, Young-Woock;
Lin, Han;
Tang, Lichun;
Zhu, Qing;
Zhang, Dan;
Chen, Huan;
Han, Suxia;
Zhang, Pumin

Publication type:

Article

Quantitation of circulating GDF-11 and β2-MG in aged patients with age-related impairment in cognitive function.

Published in:

Clinical Science, 2017, v. 131, n. 15, p. 1895, doi. 10.1042/CS20171028

By:

Rungong Yang;
Shuhong Fu;
Liang Zhao;
Bei Zhen;
Ling Ye;
Xiaolu Niu;
Xiaoxia Li;
Pumin Zhang;
Jie Bai

Publication type:

Article

Ubiquitin‐specific protease 28 deubiquitinates TCF7L2 to govern the action of the Wnt signaling pathway in hepatic carcinoma.

Published in:

Cancer Science, 2022, v. 113, n. 10, p. 3463, doi. 10.1111/cas.15509

By:

Sun, Xiao;
Cai, Mengjiao;
Wu, Lingzhi;
Zhen, Xinghua;
Chen, Yuetong;
Peng, Jin;
Han, Suxia;
Zhang, Pumin

Publication type:

Article

RECQL5 plays an essential role in maintaining genome stability and viability of triple‐negative breast cancer cells.

Published in:

Cancer Medicine, 2019, v. 8, n. 10, p. 4743, doi. 10.1002/cam4.2349

By:

Peng, Jin;
Tang, Lichun;
Cai, Mengjiao;
Chen, Huan;
Wong, Jiemin;
Zhang, Pumin

Publication type:

Article

Efficient gene editing in adult mouse livers via adenoviral delivery of CRISPR/Cas9.

Published in:

FEBS Letters, 2014, v. 588, n. 21, p. 3954, doi. 10.1016/j.febslet.2014.09.008

By:

Cheng, Ranran;
Peng, Jin;
Yan, Yonghong;
Cao, Peili;
Wang, Jiewei;
Qiu, Chen;
Tang, Lichun;
Liu, Di;
Tang, Li;
Jin, Jianping;
Huang, Xingxu;
He, Fuchu;
Zhang, Pumin

Publication type:

Article

Towards genetic genome projects: genomic library screening and gene-targeting vector construction in a single step.

Published in:

Nature Genetics, 2002, v. 30, n. 1, p. 31, doi. 10.1038/ng797

By:

Zhang, Pumin;
Li, Mamei Z.;
Elledge, Stephen J.

Publication type:

Article

BRIT1/MCPH1 Is Essential for Mitotic and Meiotic Recombination DNA Repair and Maintaining Genomic Stability in Mice.

Published in:

PLoS Genetics, 2010, v. 6, n. 1, p. 1, doi. 10.1371/journal.pgen.1000826

By:

Yulong Liang;
Hong Gao;
Shiaw-Yih Lin;
Guang Peng;
Xingxu Huang;
Pumin Zhang;
Goss, John A.;
Brunicardi, Francis C.;
Multani, Asha S.;
Sandy Chang;
Kaiyi Li

Publication type:

Article

Hypomorphism of Fto and Rpgrip1l causes obesity in mice.

Published in:

Journal of Clinical Investigation, 2016, v. 126, n. 5, p. 1897, doi. 10.1172/JCI85526

By:

Stratigopoulos, George;
Burnett, Lisa Cole;
Rausch, Richard;
Gill, Richard;
Penn, David Barth;
Skowronski, Alicja A.;
LeDuc, Charles A.;
Lanzano, Anthony J.;
Pumin Zhang;
Storm, Daniel R.;
Egli, Dieter;
Leibel, Rudolph L.

Publication type:

Article

Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice.

Published in:

2014

By:

Yu, Da-Hai;
Waterland, Robert A;
Zhang, Pumin;
Schady, Deborah;
Chen, Miao-Hsueh;
Guan, Yongtao;
Gadkari, Manasi;
Shen, Lanlan

Publication type:

journal article

Targeted p16Ink4a epimutation causes tumorigenesis and reduces survival in mice.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3708, doi. 10.1172/JCI76507

By:

Da-Hai Yu;
Waterland, Robert A.;
Pumin Zhang;
Schady, Deborah;
Miao-Hsueh Chen;
Yongtao Guan;
Gadkari, Manasi;
Lanlan Shen

Publication type:

Article

The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes.

Published in:

2004

By:

MacLean, Helen E;
Guo, Jun;
Knight, Melissa C;
Zhang, Pumin;
Cobrinik, David;
Kronenberg, Henry M

Publication type:

journal article

The cyclin-dependent kinase inhibitor p57Kip2 mediates proliferative actions of PTHrP in chondrocytes.

Published in:

Journal of Clinical Investigation, 2004, v. 113, n. 9, p. 1334, doi. 10.1172/JCI200421252

By:

MacLean, Helen E.;
Jun Guo;
Knight, Melissa C.;
Pumin Zhang;
Cobrinik, David;
Kronenberg, Henry M.

Publication type:

Article

Advances in preclinical and clinical studies of oncolytic virus combination therapy.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1545542

By:

Du, Wenlong;
Na, Jintong;
Zhong, Liping;
Zhang, Pumin

Publication type:

Article

Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors.

Published in:

Genes, 2022, v. 13, n. 5, p. 803, doi. 10.3390/genes13050803

By:

Li, Junjun;
Lan, Mengjiao;
Peng, Jin;
Xiong, Qunli;
Xu, Yongfeng;
Yang, Yang;
Zhou, Ying;
Liu, Jinlu;
Zeng, Zhu;
Yang, Xiaojuan;
Zhang, Zhiwei;
Zhang, Pumin;
Zhu, Qing;
Wu, Wei

Publication type:

Article

The NEK1 interact or, C21ORF2, is required for efficient DNA damage repair.

Published in:

Acta Biochimica et Biophysica Sinica, 2015, v. 47, n. 10, p. 834, doi. 10.1093/abbs/gmv076

By:

Xiao Fang;
Han Lin;
Xiaohui Wang;
Qiuhong Zuo;
Jun Qin;
Pumin Zhang

Publication type:

Article

Loss of spindle assembly checkpoint--mediated inhibition of Cdc20 promotes tumorigenesis in mice.

Published in:

Journal of Cell Biology, 2009, v. 185, n. 6, p. 983, doi. 10.1083/jcb.200904020

By:

Min Li;
Xiao Fang;
Zhubo Wei;
York, J. Philippe;
Zhang, Pumin

Publication type:

Article

Transcription-Replication Collisions and Chromosome Fragility.

Published in:

Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.804547

By:

Wu, Wei;
He, Jing Na;
Lan, Mengjiao;
Zhang, Pumin;
Chu, Wai Kit

Publication type:

Article

Viral N protein hijacks deaminase-containing RNA granules to enhance SARS-CoV-2 mutagenesis.

Published in:

EMBO Journal, 2024, v. 43, n. 24, p. 6444, doi. 10.1038/s44318-024-00314-y

By:

Li, Zhean;
Luo, Lingling;
Ju, Xiaohui;
Huang, Shisheng;
Lei, Liqun;
Yu, Yanying;
Liu, Jia;
Zhang, Pumin;
Chi, Tian;
Ma, Peixiang;
Huang, Cheng;
Huang, Xingxu;
Ding, Qiang;
Zhang, Yu

Publication type:

Article

USP25 regulates KEAP1-NRF2 anti-oxidation axis and its inactivation protects acetaminophen-induced liver injury in male mice.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39412-6

By:

Cai, Changzhou;
Ma, Huailu;
Peng, Jin;
Shen, Xiang;
Zhen, Xinghua;
Yu, Chaohui;
Zhang, Pumin;
Ji, Feng;
Wang, Jiewei

Publication type:

Article

METTL14 suppresses the expression of YAP1 and the stemness of triple-negative breast cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, p. 1, doi. 10.1186/s13046-024-03225-2

By:

Bai, Xupeng;
Liu, Jiarui;
Zhou, Shujie;
Wu, Lingzhi;
Feng, Xiaojie;
Zhang, Pumin

Publication type:

Article

A phosphatase turns aggressive: The oncogenicity of Cdc14B.

Published in:

Cell Cycle, 2011, v. 10, n. 15, p. 2414, doi. 10.4161/cc.10.15.15887

By:

Zhubo Wei;
Pumin Zhang

Publication type:

Article

The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression.

Published in:

Cell Cycle, 2011, v. 10, n. 4, p. 671, doi. 10.4161/cc.10.4.14901

By:

Peddibhotla, Sirisha;
Zhubo Wei;
Papineni, Rao;
Lam, Micheal H.;
Rosen, Jeffrey M.;
Zhang, Pumin

Publication type:

Article

Spindle assembly checkpoint, aneuploidy and tumorigenesis.

Published in:

Cell Cycle, 2009, v. 8, n. 21, p. 3440, doi. 10.4161/cc.8.21.9688

By:

Min Li;
Pumin Zhang

Publication type:

Article

Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.

Published in:

Molecular & Cellular Biology, 2015, v. 35, n. 21, p. 3657, doi. 10.1128/MCB.00233-15

By:

Han Lin;
Kyungsoo Ha;
Guojun Lu;
Xiao Fang;
Ranran Cheng;
Qiuhong Zuo;
Pumin Zhang

Publication type:

Article

Early-Onset Aging and Defective DNA Damage Response in Cdc14b-Deficient Mice.

Published in:

Molecular & Cellular Biology, 2011, v. 31, n. 7, p. 1470, doi. 10.1128/MCB.01330-10

By:

Zhubo Wei;
Peddibhotla, Sirisha;
Han Lin;
Xiao Fang;
Min Li;
Rosen, Jeffrey M.;
Pumin Zhang

Publication type:

Article

Type I Phosphatidylinositol Phosphate Kinase Beta Regulates Focal Adhesion Disassembly by Promoting β1 Integrin Endocytosis.

Published in:

Molecular & Cellular Biology, 2010, v. 30, n. 18, p. 8, doi. 10.1128/MCB.01207-09

By:

Wei-Ting Chao;
Ashcroft, Felicity;
Daquinag, Alexes C.;
Vadakkan, Tegy;
Zhubo Wei;
Pumin Zhang;
Dickinson, Mary E.;
Kunz, Jeannette

Publication type:

Article

Preimplantation Mouse Embryos Depend on Inhibitory Phosphorylation of Separase To Prevent Chromosome Missegregation.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 6, p. 10, doi. 10.1128/MCB.01778-08

By:

Xingxu Huang;
Andreu-Vieyra, Claudia V.;
Meizhi Wang;
Cooney, Austin J.;
Matzuk, Martin M.;
Pumin Zhang

Publication type:

Article

The Notch Signaling Pathway Controls the Size of the Ocular Lens by Directly Suppressing p57Kip2 Expression.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 20, p. 21, doi. 10.1128/MCB.00780-07

By:

Junling Jia;
Min Lin;
Lingna Zhang;
York, J. Philippe;
Zhang, Pumin

Publication type:

Article

Loss of Cdc20 Causes a Securin-Dependent Metaphase Arrest in Two-Cell Mouse Embryos.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 9, p. 19, doi. 10.1128/MCB.02088-06

By:

Min Li;
York, J. Philippe;
Pumin Zhang

Publication type:

Article

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-

Published in:

Nature, 1997, v. 387, n. 6629, p. 151, doi. 10.1038/387151a0

By:

Zhang, Pumin;
Liegeois, Nanette J.

Publication type:

Article

The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites.

Published in:

Nature Communications, 2017, v. 8, n. 6, p. 15751, doi. 10.1038/ncomms15751

By:

Ha, Kyungsoo;
Ma, Chengxian;
Lin, Han;
Tang, Lichun;
Lian, Zhusheng;
Zhao, Fang;
Li, Ju-Mei;
Zhen, Bei;
Pei, Huadong;
Han, Suxia;
Malumbres, Marcos;
Jin, Jianping;
Chen, Huan;
Zhao, Yongxiang;
Zhu, Qing;
Zhang, Pumin

Publication type:

Article

A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice.

Published in:

Nature Communications, 2016, v. 7, n. 1, p. 10201, doi. 10.1038/ncomms10201

By:

Zhang, Haoxing;
Liu, Hailong;
Chen, Yali;
Yang, Xu;
Wang, Panfei;
Liu, Tongzheng;
Deng, Min;
Qin, Bo;
Correia, Cristina;
Lee, Seungbaek;
Kim, Jungjin;
Sparks, Melanie;
Nair, Asha A.;
Evans, Debra L.;
Kalari, Krishna R.;
Zhang, Pumin;
Wang, Liewei;
You, Zhongsheng;
Kaufmann, Scott H.;
Lou, Zhenkun

Publication type:

Article

Ca2+ permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca2+ signaling to sustain muscle function.

Published in:

Skeletal Muscle, 2015, v. 5, n. 1, p. 1, doi. 10.1186/s13395-014-0027-1

By:

Chang Seok Lee;
Dagnino-Acosta, Adan;
Yarotskyy, Viktor;
Hanna, Amy;
Lyfenko, Alla;
Knoblauch, Mark;
Georgiou, Dimitra K.;
Poché, Ross A.;
Swank, Michael W.;
Cheng Long;
Ismailov, Iskander I.;
Lanner, Johanna;
Tran, Ted;
KeKe Dong;
Rodney, George G.;
Dickinson, Mary E.;
Beeton, Christine;
Pumin Zhang;
Dirksen, Robert T.;
Hamilton, Susan L.

Publication type:

Article

Ca2+ permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca2+ signaling to sustain muscle function.

Published in:

Skeletal Muscle, 2015, v. 5, n. 1, p. 53, doi. 10.1186/s13395-014-0027-1

By:

Chang Seok Lee;
Dagnino-Acosta, Adan;
Yarotskyy, Viktor;
Hanna, Amy;
Lyfenko, Alla;
Knoblauch, Mark;
Georgiou, Dimitra K.;
Poché, Ross A.;
Swank, Michael W.;
Cheng Long;
Ismailov, Iskander I.;
Lanner, Johanna;
Tran, Ted;
KeKe Dong;
Rodney, George G.;
Dickinson, Mary E.;
Beeton, Christine;
Pumin Zhang;
Dirksen, Robert T.;
Hamilton, Susan L.

Publication type:

Article

Podocyte expression of the CDK-inhibitor p57 during development and disease.

Published in:

Kidney International, 2001, v. 60, n. 6, p. 2235, doi. 10.1046/j.1523-1755.2001.00057.x

By:

Hiromura, Keiju;
Haseley, Leah A.;
Zhang, Pumin;
Monkawa, Toshiaki;
Durvasula, Raghu;
Petermann, Arndt T.;
Alpers, Charles E.;
Mundel, Peter;
Shankland, Stuart J.

Publication type:

Article

Identification of a class of potent USP25/28 inhibitors with broad-spectrum anti-cancer activity.

Published in:

2022

By:

Peng, Jin;
Jiang, Kun;
Sun, Xiao;
Wu, Lingzhi;
Wang, Jiewei;
Xi, Xiaomei;
Tan, Xu;
Liang, Tingbo;
Tan, Changheng;
Zhang, Pumin

Publication type:

Letter

LGR4 attenuates MGP expression and suppresses EGFR activation-induced triple-negative breast cancer metastasis.

Published in:

American Journal of Cancer Research, 2024, v. 14, n. 7, p. 3419, doi. 10.62347/THII9650

By:

Qishuang Li;
Yankun Gao;
Zitian Huo;
Jing Liu;
Pumin Zhang;
Yi Wang

Publication type:

Article

Erratum: The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites.

Published in:

Nature Communications, 2017, v. 8, n. 11, p. 16156, doi. 10.1038/ncomms16156

By:

Ha, Kyungsoo;
Ma, Chengxian;
Lin, Han;
Tang, Lichun;
Lian, Zhusheng;
Zhao, Fang;
Li, Ju-Mei;
Zhen, Bei;
Pei, Huadong;
Han, Suxia;
Malumbres, Marcos;
Jin, Jianping;
Chen, Huan;
Zhao, Yongxiang;
Zhu, Qing;
Zhang, Pumin

Publication type:

Article

Preclinical testing of CT1113, a novel USP28 inhibitor, for the treatment of T‐cell acute lymphoblastic leukaemia.

Published in:

British Journal of Haematology, 2024, v. 204, n. 6, p. 2301, doi. 10.1111/bjh.19492

By:

Xu, Jieyu;
Peng, Jin;
Sun, Shu;
Wang, Donghai;
Yuan, Wei;
Yang, Xueying;
Shi, Ting;
Wang, Rong;
Liu, Hudan;
Zhang, Pumin;
Zhu, Hong‐Hu

Publication type:

Article

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.

Published in:

EMBO Journal, 2008, v. 27, n. 14, p. 1932, doi. 10.1038/emboj.2008.120

By:

Facchinetti, Valeria;
Weiming Ouyang;
Hua Wei;
Soto, Nelyn;
Lazorchak, Adam;
Gould, Christine;
Lowry, Carolyn;
Newton, Alexandra C;
Yuxin Mao;
Miao, Robert Q;
Sessa, William C.;
Jun Qin;
Pumin Zhang;
Bing Su;
Jacinto, Estela

Publication type:

Article

Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse.

Published in:

FASEB Journal, 2006, v. 20, n. 2, p. 329, doi. 10.1096/fj.05-4497fje

By:

Chelu, Mihail G.;
Goonasekera, Sanjeewa A.;
Durham, William J.;
Wei Tang;
Lueck, John D.;
Riehl, Joyce;
Pessah, Isaac N.;
Pumin Zhang;
Bhattacharjee, Meenakshi B.;
Dirksen, Robert T.;
Hamilton, Susan L.

Publication type:

Article

Highly efficient ssODN‐mediated homology‐directed repair of DSBs generated by CRISPR/Cas9 in human 3PN zygotes.

Published in:

Molecular Reproduction & Development, 2018, v. 85, n. 6, p. 461, doi. 10.1002/mrd.22983

By:

Tang, Lichun;
Zeng, Yanting;
Zhou, Xuewei;
Du, Hongzi;
Li, Chuang;
Liu, Jianqiao;
Zhang, Pumin

Publication type:

Article

Production of a mouse line with a conditional Crim1 mutant allele.

Published in:

Genesis: The Journal of Genetics & Development, 2012, v. 50, n. 9, p. 711, doi. 10.1002/dvg.22032

By:

Chiu, Han Sheng;
York, J. Philippe;
Wilkinson, Lorine;
Zhang, Pumin;
Little, Melissa H.;
Pennisi, David J.

Publication type:

Article

Functional Phosphoproteomics in Cancer Chemoresistance Using CRISPR‐Mediated Base Editors.

Published in:

Advanced Science, 2022, v. 9, n. 30, p. 1, doi. 10.1002/advs.202200717

By:

Li, Jianan;
Lin, Jianxiang;
Huang, Shisheng;
Li, Min;
Yu, Wenxia;
Zhao, Yuting;
Guo, Junfan;
Zhang, Pumin;
Huang, Xingxu;
Qiao, Yunbo

Publication type:

Article

The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory.

Published in:

Nature Cell Biology, 2008, v. 10, n. 9, p. 1083, doi. 10.1038/ncb1768

By:

Min Li;
Yong-Hyun Shin;
Lingfei Hou;
Xingxu Huang;
Zhubo Wei;
Klann, Eric;
Pumin Zhang

Publication type:

Article

Targeting of GFP-Cre to the Mouse Cyp11a1 Locus Both Drives Cre Recombinase Expression in Steroidogenic Cells and Permits Generation of Cyp11a1 Knock Out Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0084541

By:

O'Hara, Laura;
York, Jean Philippe;
Zhang, Pumin;
Smith, Lee B.

Publication type:

Article

The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice.

Published in:

PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0014005

By:

Xue Gao;
Yong-Hyun Shin;
Min Li;
Fei Wang;
Qiang Tong;
Pumin Zhang

Publication type:

Article

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

Published in:

Cell Research, 2013, v. 23, n. 5, p. 720, doi. 10.1038/cr.2013.46

By:

Shen, Bin;
Zhang, Jun;
Wu, Hongya;
Wang, Jianying;
Ma, Ke;
Li, Zheng;
Zhang, Xueguang;
Zhang, Pumin;
Huang, Xingxu

Publication type:

Article

Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads.

Published in:

Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05330-y

By:

Lee, Chang Seok;
Jung, Sung Yun;
Yee, Rachel Sue Zhen;
Agha, Nadia H.;
Hong, Jin;
Chang, Ting;
Babcock, Lyle W.;
Fleischman, Jorie D.;
Clayton, Benjamin;
Hanna, Amy D.;
Ward, Christopher S.;
Lanza, Denise;
Hurley, Ayrea E.;
Zhang, Pumin;
Wehrens, Xander H. T.;
Lagor, William R.;
Rodney, George G.;
Hamilton, Susan L.

Publication type:

Article