Works by Przedborski, Serge

Results: 107

Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson’s disease.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39652-6

By:

Irmady, Krithi;
Hale, Caryn R.;
Qadri, Rizwana;
Fak, John;
Simelane, Sitsandziwe;
Carroll, Thomas;
Przedborski, Serge;
Darnell, Robert B.

Publication type:

Article

α-Synuclein Overexpression Increases Cytosolic Catecholamine Concentration.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 36, p. 9304, doi. 10.1523/JNEUROSCI.0519-06.2006

By:

Mosharov, Eugene V.;
Staal, Roland G. W.;
Bove, Jordi;
Prou, Delphine;
Hananiya, Anthonia;
Markov, Dmitriy;
Poulsen, Nathan;
Larsen, Kristin E.;
Moore, Candace M. H.;
Troyer, Matthew D.;
Edwards, Robert H.;
Przedborski, Serge;
Sulzer, David

Publication type:

Article

Metabolism of 3-Nitrotyrosine Induces Apoptotic Death in Dopaminergic Cells.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 23, p. 6124, doi. 10.1523/JNEUROSCI.1038-06.2006

By:

Blanchard-Fillion, Béatrice;
Prou, Delphine;
Polydoro, Manuela;
Spielberg, David;
Tsika, Elpida;
Zeneng Wang;
Hazen, Stanley L.;
Koval, Michael;
Przedborski, Serge;
Ischiropoulos, Harry

Publication type:

Article

Ablation of the Inflammatory Enzyme Myeloperoxidase Mitigates Features of Parkinson's Disease in Mice.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 28, p. 6594, doi. 10.1523/JNEUROSCI.0970-05.2005

By:

Dong-Kug Choi;
Pennathur, Subramaniam;
Perier, Celine;
Tieu, Kim;
Teismann, Peter;
Du-Chu Wu;
Jackson-Lewis, Vernice;
Vila, Miquel;
Vonsattel, Jean-Paul;
Heinecke, Jay W.;
Przedborski, Serge

Publication type:

Article

Regulation of Dopaminergic Loss by Fas in a 1-Methyl-4-Phenyl- 1,2,3,6-Tetrahydropyridine Model of Parkinson's Disease.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 8, p. 2045, doi. 10.1523/JNEUROSCI.4564-03.2004

By:

Hayley, Shawn;
Crocker, Stephen J.;
Smith, Patrice D.;
Shree, Tanaya;
Jackson-Lewis, Vernice;
Przedborski, Serge;
Mount, Matthew;
Slack, Ruth;
Anisman, Hymie;
Park, David S.

Publication type:

Article

Enriched Environment Confers Resistance to 1-Methyl-4-Phenyl-1, 2,3,6-Tetrahydropyridine and Cocaine: Involvement of Dopamine Transporter and Trophic Factors.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 35, p. 10999, doi. 10.1523/JNEUROSCI.23-35-10999.2003

By:

Bezard, Erwan;
Dovero, Sandra;
Belin, David;
Duconger, Sophie;
Jackson-Lewis, Vernice;
Przedborski, Serge;
Piazza, Pier Vincenzo;
Gross, Christian E.;
Jaber, Mohamed

Publication type:

Article

Inhibition of Calpains Prevents Neuronal and Behavioral Deficits in an MPTP Mouse Model of Parkinson's Disease.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 10, p. 4081, doi. 10.1523/JNEUROSCI.23-10-04081.2003

By:

Crocker, Stephen J.;
Smith, Patrice D.;
Jackson-Lewis, Vernice;
Lamba, Wiplore R.;
Hayley, Shawn P.;
Grimm, Erich;
Callaghan, Steve M.;
Slack, Ruth S.;
Melloni, Edon;
Przedborski, Serge;
Robertson, George S.;
Anisman, Hymie;
Merali, Zul;
Park, David S.

Publication type:

Article

Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins.

Published in:

Annals of Neurology, 2010, v. 68, n. 2, p. 184, doi. 10.1002/ana.22034

By:

Perier, Celine;
Bové, Jordi;
Dehay, Benjamin;
Jackson-Lewis, Vernice;
Rabinovitch, Peter S.;
Przedborski, Serge;
Vila, Miquel

Publication type:

Article

Proteasome inhibition and Parkinson's disease modeling.

Published in:

Annals of Neurology, 2006, v. 60, n. 2, p. 260

By:

Jordi Bové;
Chun Zhou;
Vernice Jackson‐Lewis;
Julie Taylor;
Yaping Chu;
Hardy J. Rideout;
Du‐Chu Wu;
Jeffrey H. Kordower;
Leonard Petrucelli;
Serge Przedborski

Publication type:

Article

Is prostaglandin E2 a pathogenic factor in amyotrophic lateral sclerosis?

Published in:

Annals of Neurology, 2006, v. 59, n. 6, p. 980

By:

Gabriele Almer;
Hitoshi Kikuchi;
Peter Teismann;
Serge Przedborski

Publication type:

Article

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia.

Published in:

Annals of Neurology, 2005, v. 58, n. 6, p. 858

By:

Xiaohong Li;
Lewis P. Rowland;
Hiroshi Mitsumoto;
Serge Przedborski;
Thomas D. Bird;
Gerard D. Schellenberg;
Elaine Peskind;
Nancy Johnson;
Teepu Siddique;
M‐Marsel Mesulam;
Sandra Weintraub;
James A. Mastrianni

Publication type:

Article

L‐3‐hydroxyacyl‐CoA dehydrogenase II protects in a model of Parkinson's disease.

Published in:

Annals of Neurology, 2004, v. 56, n. 1, p. 51

By:

Kim Tieu;
Celine Perier;
Miquel Vila;
Casper Caspersen;
Hui‐Ping Zhang;
Peter Teismann;
Vernice Jackson‐Lewis;
David M. Stern;
Shi Du Yan;
Serge Przedborski

Publication type:

Article

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

Published in:

Annals of Neurology, 2002, v. 52, n. 6, p. 771, doi. 10.1002/ana.10374

By:

Drachman, Daniel B.;
Frank, Krystl;
Dykes-Hoberg, Margaret;
Teismann, Peter;
Almer, Gabrielle;
Przedborski, Serge;
Rothstein, Jeffrey D.

Publication type:

Article

Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis.

Published in:

Annals of Neurology, 2001, v. 49, n. 2, p. 176, doi. 10.1002/1531-8249(20010201)49:2<176::AID-ANA37>3.0.CO;2-X

By:

Almer, Gabrielle;
Guégan, Christelle;
Teismann, Peter;
Naini, Ali;
Rosoklija, Gorazd;
Hays, Arthur P.;
Chen, Caiping;
Przedborski, Serge

Publication type:

Article

A novel mitochondrial 12SrRNA point mutation in parkinsonism, deafness, and neuropathy.

Published in:

Annals of Neurology, 2000, v. 48, n. 5, p. 730, doi. 10.1002/1531-8249(200011)48:5<730::AID-ANA6>3.0.CO;2-0

By:

Thyagarajan, Dominic;
Bressman, Susan;
Bruno, Claudio;
Przedborski, Serge;
Shanske, Sara;
Lynch, Timothy;
Fahn, Stanley;
DiMauro, Salvatore

Publication type:

Article

Does increased superoxide dismutase activity really cause muscular dystrophy?

Published in:

1999

By:

Almer, Gabriele;
Rosoklija, Gorazd;
Hirano, Michio;
Hays, Arthur P.;
Przedborski, Serge;
Almer, G;
Rosoklija, G;
Hirano, M;
Hays, A P;
Przedborski, S

Publication type:

commentary

Brain superoxide dismutase, catalase, and glutathione peroxidase activities in amyotrophic lateral sclerosis.

Published in:

Annals of Neurology, 1996, v. 39, n. 2, p. 158, doi. 10.1002/ana.410390204

By:

Przedborski, Serge;
Donaldson, David;
Jakowec, Michael;
Kish, Stephen J.;
Guttman, M.;
Rosoklija, Gorazd;
Hays, Arthur P.

Publication type:

Article

Neuroleptic medications inhibit complex I of the electron transport chain.

Published in:

1994

By:

Jackson-Lewis, Vernice;
Przedborski, Serge;
Jackson-Lewis, V;
Przedborski, S

Publication type:

commentary

Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity.

Published in:

Annals of Neurology, 1993, v. 34, n. 5, p. 715, doi. 10.1002/ana.410340515

By:

Przedborski, Serge;
Jackson-Lewis, Vernice;
Muthane, Uday;
Jiang, Hong;
Ferreira, Mayra;
Naini, Ali B.;
Fahn, Stanley

Publication type:

Article

Alpha-tocopherol levels in parkinsonian brains.

Published in:

1993

By:

Przedborski, Serge;
Jackson-Lewis, Vernice;
Muthane, Uday;
Dexter, D. T.;
Jenner, P.;
Marsden, C. D.;
Przedborski, S;
Jackson-Lewis, V;
Muthane, U

Publication type:

commentary

Lack of changes in ventricular cerebrospinal fluid concentrations of homovanillic acid following acute challenge with levodopa.

Published in:

1992

By:

Moussa, Zouheir;
Raftopoulos, Christian;
Przedborski, Serge;
Hildebrand, Jerzy;
Moussa, Z;
Raftopoulos, C;
Przedborski, S;
Hildebrand, J

Publication type:

commentary

Neurotensin receptors in human meningiomas.

Published in:

Annals of Neurology, 1991, v. 30, n. 5, p. 650, doi. 10.1002/ana.410300504

By:

Przedborski, Serge;
Levivier, Marc;
Cadet, Jean Lud

Publication type:

Article

Patterns of TDP‐43 Deposition in Brains with LRRK2 G2019S Mutations.

Published in:

Movement Disorders, 2023, v. 38, n. 8, p. 1541, doi. 10.1002/mds.29449

By:

Agin‐Liebes, Julian;
Hickman, Richard A.;
Vonsattel, Jean Paul;
Faust, Phyllis L.;
Flowers, Xena;
Utkina Sosunova, Irina;
Ntiri, Joel;
Mayeux, Richard;
Surface, Matthew;
Marder, Karen;
Fahn, Stanley;
Przedborski, Serge;
Alcalay, Roy N.

Publication type:

Article

Reply to: "Letter on Discussion of Gait Research".

Published in:

2022

By:

Bohnen, Nicolaas I.;
Costa, Rui M.;
Dauer, William T.;
Factor, Stewart A.;
Giladi, Nir;
Hallett, Mark;
Lewis, Simon J.G.;
Nieuwboer, Alice;
Nutt, John G.;
Takakusaki, Kaoru;
Kang, Un Jung;
Przedborski, Serge;
Papa, Stella M.

Publication type:

Letter

Discussion of Research Priorities for Gait Disorders in Parkinson's Disease.

Published in:

Movement Disorders, 2022, v. 37, n. 2, p. 253, doi. 10.1002/mds.28883

By:

Bohnen, Nicolaas I.;
Costa, Rui M.;
Dauer, William T.;
Factor, Stewart A.;
Giladi, Nir;
Hallett, Mark;
Lewis, Simon J.G.;
Nieuwboer, Alice;
Nutt, John G.;
Takakusaki, Kaoru;
Kang, Un Jung;
Przedborski, Serge;
Papa, Stella M.

Publication type:

Article

Addressing the Challenges of Clinical Research for Freezing of Gait in Parkinson's Disease.

Published in:

Movement Disorders, 2022, v. 37, n. 2, p. 264, doi. 10.1002/mds.28837

By:

Lewis, Simon J.G.;
Factor, Stewart A.;
Giladi, Nir;
Hallett, Mark;
Nieuwboer, Alice;
Nutt, John G.;
Przedborski, Serge;
Papa, Stella M.

Publication type:

Article

Recent Advances in the Development of Stem‐Cell‐Derived Dopaminergic Neuronal Transplant Therapies for Parkinson's Disease.

Published in:

Movement Disorders, 2021, v. 36, n. 8, p. 1772, doi. 10.1002/mds.28628

By:

Barbuti, Peter A.;
Barker, Roger A.;
Brundin, Patrik;
Przedborski, Serge;
Papa, Stella M.;
Kalia, Lorraine V.;
Mochizuki, Hideki

Publication type:

Article

A new role for α-synuclein in Parkinson's disease: Alteration of ER-mitochondrial communication.

Published in:

Movement Disorders, 2015, v. 30, n. 8, p. 1026, doi. 10.1002/mds.26239

By:

Guardia-Laguarta, Cristina;
Area-Gomez, Estela;
Schon, Eric A.;
Przedborski, Serge

Publication type:

Article

Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy.

Published in:

EMBO Reports, 2014, v. 15, n. 1, p. 86, doi. 10.1002/embr.201337294

By:

Fedorowicz, Maja A.;
Vries Schneider, Rosa L. A.;
Rüb, Cornelia;
Becker, Dorothea;
Huang, Yong;
Zhou, Chun;
Alessi Wolken, Dana M.;
Voos, Wolfgang;
Liu, Yuhui;
Przedborski, Serge

Publication type:

Article

Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine.

Published in:

European Journal of Neuroscience, 2001, v. 14, n. 9, p. 1425, doi. 10.1046/j.0953-816X.2001.01765.x

By:

Petersén, Åsa;
Hansson, Oskar;
Puschban, Zoe;
Sapp, Ellen;
Romero, Norma;
Castilho, Roger F.;
Sulzer, David;
Rice, Margaret;
DiFiglia, Marian;
Przedborski, Serge;
Brundin, Patrik

Publication type:

Article

α-Synuclein-Independent Histopathological and Motor Deficits in Mice Lacking the Endolysosomal Parkinsonism Protein Atp13a2.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 14, p. 5724, doi. 10.1523/JNEUROSCI.0632-14.2015

By:

Kett, Lauren R.;
Stiller, Barbara;
Bernath, Megan M.;
Tasset, Inmaculada;
Blesa, Javier;
Jackson-Lewis, Vernice;
Chan, Robin B.;
Zhou, Bowen;
Di Paolo, Gilbert;
Przedborski, Serge;
Cuervo, Ana Maria;
Dauer, William T.

Publication type:

Article

α-Synuclein Is Localized to Mitochondria-Associated ER Membranes.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 1, p. 249, doi. 10.1523/JNEUROSCI.2507-13.2014

By:

Guardia-Laguarta, Cristina;
Area-Gomez, Estela;
Rüb, Cornelia;
Yuhui Liu;
Magrané, Jordi;
Becker, Dorothea;
Voos, Wolfgang;
Schon, Eric A.;
Przedborski, Serge

Publication type:

Article

Classic and New Animal Models of Parkinson's Disease.

Published in:

2012

By:

Blesa, Javier;
Phani, Sudarshan;
Jackson-Lewis, Vernice;
Przedborski, Serge

Publication type:

Journal Article

Classic and New Animal Models of Parkinson's Disease.

Published in:

Journal of Biomedicine & Biotechnology, 2012, v. 2012, p. 1, doi. 10.1155/2012/845618

By:

Blesa, Javier;
Phani, Sudarshan;
Jackson-Lewis, Vernice;
Przedborski, Serge

Publication type:

Article

Deciphering amyotrophic lateral sclerosis: What phenotype, neuropathology and genetics are telling us about pathogenesis.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2013, p. 5, doi. 10.3109/21678421.2013.778548

By:

RAVITS, JOHN;
APPEL, STANLEY;
BALOH, ROBERT H.;
BAROHN, RICHARD;
BROOKS, BENJAMIN RIX;
ELMAN, LAUREN;
FLOETER, MARY KAY;
HENDERSON, CHRISTOPHER;
LOMEN-HOERTH, CATHERINE;
MACKLIS, JEFFREY D.;
MCCLUSKEY, LEO;
MITSUMOTO, HIROSHI;
PRZEDBORSKI, SERGE;
ROTHSTEIN, JEFFREY;
TROJANOWSKI, JOHN Q.;
VAN DEN BERG, LEONARD H.;
RINGEL, STEVEN

Publication type:

Article

Deciphering amyotrophic lateral sclerosis: What phenotype, neuropathology and genetics are telling us about pathogenesis.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2013, v. 14, p. 5, doi. 10.3109/21678421.2013.778548

By:

Ravits, John;
Appel, Stanley;
Baloh, Robert H.;
Barohn, Richard;
Rix Brooks, Benjamin;
Elman, Lauren;
Floeter, Mary Kay;
Henderson, Christopher;
Lomen-Hoerth, Catherine;
Macklis, Jeffrey D.;
McCluskey, Leo;
Mitsumoto, Hiroshi;
Przedborski, Serge;
Rothstein, Jeffrey;
Trojanowski, John Q.;
van den Berg, Leonard H.;
Ringel, Steven

Publication type:

Article

Nitric Oxide and Reactive Oxygen Species in Parkinson's Disease.

Published in:

IUBMB Life, 2003, v. 55, n. 6, p. 329, doi. 10.1080/1521654032000114320

By:

Tieu, Kim;
Ischiropoulos, Harry;
Przedborski, Serge

Publication type:

Article

The Postnatal Development of AMPA Receptor Subunits in the Basal Ganglia of the Rat.

Published in:

Developmental Neuroscience, 1998, v. 20, n. 1, p. 19, doi. 10.1159/000017295

By:

Jakowec, Michael W.;
Jackson-Lewis, Vernice;
Chen, Xiaoqiong;
Langston, J. William;
Przedborski, Serge

Publication type:

Article

Peroxiredoxin-2 links Cdk5 to neurodegeneration.

Published in:

Nature Medicine, 2007, v. 13, n. 8, p. 907, doi. 10.1038/nm0807-907

By:

Przedborski, Serge

Publication type:

Article

Genetic clues to the pathogenesis of Parkinson's disease.

Published in:

Nature Medicine, 2004, v. 10, p. S58, doi. 10.1038/nm1068

By:

Vila, Miquel;
Przedborski, Serge

Publication type:

Article

COVID-19 manifestations in people with Parkinson's disease: a USA cohort.

Published in:

Journal of Neurology, 2022, v. 269, n. 3, p. 1107, doi. 10.1007/s00415-021-10784-3

By:

Xu, Yaqian;
Surface, Matthew;
Chan, Amanda K.;
Halpern, Joshua;
Vanegas-Arroyave, Nora;
Ford, Blair;
Feeney, Megan P.;
Kwei, Kimberly T.;
Katus, Linn E.;
Kuo, Sheng-Han;
Shah, Hiral;
Waters, Cheryl;
Winfield, Linda M.;
Beck, James C.;
Przedborski, Serge;
Fahn, Stanley;
Alcalay, Roy N.

Publication type:

Article

Pathogenesis of Parkinson's disease.

Published in:

Movement Disorders, 2013, v. 28, n. 1, p. 24, doi. 10.1002/mds.25032

By:

Hirsch, Etienne C.;
Jenner, Peter;
Przedborski, Serge

Publication type:

Article

Can we reverse alpha-synuclein lesions?

Published in:

2011

By:

Przedborski, Serge

Publication type:

journal article

Can a defect in bioenergetics be involved in the pathogenesis of Parkinson's disease after all?

Published in:

Movement Disorders, 2011, v. 26, n. 8, p. 1408, doi. 10.1002/mds.23857

By:

Przedborski, Serge

Publication type:

Article

New insights into the pathophysiology of dystonia.

Published in:

Movement Disorders, 2011, v. 26, n. 8, p. 1407, doi. 10.1002/mds.23856

By:

Przedborski, Serge

Publication type:

Article

A tale on animal models of Parkinson's Disease.

Published in:

Movement Disorders, 2011, v. 26, n. 6, p. 993, doi. 10.1002/mds.23696

By:

Bezard, Erwan;
Przedborski, Serge

Publication type:

Article

Inflammation and Parkinson's disease pathogenesis.

Published in:

Movement Disorders, 2010, v. 25, n. S1, p. S55, doi. 10.1002/mds.22638

By:

Przedborski, Serge

Publication type:

Article

Clarification: Pathogenic role of glial cells in Parkinson's disease.

Published in:

Movement Disorders, 2004, v. 19, n. 1, p. 118, doi. 10.1002/mds.10701

By:

Serge Przedborski

Publication type:

Article

Pathogenic role of glial cells in Parkinson's disease.

Published in:

Movement Disorders, 2003, v. 18, n. 2, p. 121, doi. 10.1002/mds.10332

By:

Teismann, Peter;
Tieu, Kim;
Cohen, Oren;
Choi, Dong-Kug;
Wu, Du Chu;
Marks, Daniel;
Vila, Miquel;
Jackson-Lewis, Vernice;
Przedborski, Serge

Publication type:

Article

α-Synuclein expression in substantia nigra and cortex in Parkinson's disease.

Published in:

Movement Disorders, 1999, v. 14, n. 3, p. 417, doi. 10.1002/1531-8257(199905)14:3<417::AID-MDS1005>3.0.CO;2-X

By:

Neystat, Michael;
Lynch, Timothy;
Przedborski, Serge;
Kholodilov, Nikolai;
Rzhetskaya, Margarita;
Burke, Robert E.

Publication type:

Article