Found: 27
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SLCO1B1 and ABCG2 Gene Polymorphisms in a Thai Population.
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- Pharmacogenomics & Personalized Medicine, 2020, p. 521, doi. 10.2147/PGPM.S268457
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- Publication type:
- Article
Quantification of CYP3A and Drug Transporters Activity in Healthy Young, Healthy Elderly and Chronic Kidney Disease Elderly Patients by a Microdose Cocktail Approach.
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- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.726669
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- Article
Drug-Drug Interaction Studies: Regulatory Guidance and An Industry Perspective.
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- AAPS Journal, 2013, v. 15, n. 3, p. 629, doi. 10.1208/s12248-013-9470-x
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- Article
ADME of Biologics-What Have We Learned from Small Molecules?
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- AAPS Journal, 2012, v. 14, n. 3, p. 410, doi. 10.1208/s12248-012-9353-6
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- Publication type:
- Article
Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction.
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- Clinical Pharmacology & Therapeutics, 1992, v. 52, n. 5, p. 453, doi. 10.1038/clpt.1992.171
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- Publication type:
- Article
Pitavastatin is a more sensitive and selective organic anion-transporting polypeptide IB clinical probe than rosuvastatin.
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- British Journal of Clinical Pharmacology, 2014, v. 78, n. 3, p. 587, doi. 10.1111/bcp.12377
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- Publication type:
- Article
Evaluation of Pharmacokinetic Drug Interactions of the Direct-Acting Antiviral Agents Elbasvir and Grazoprevir with Pitavastatin, Rosuvastatin, Pravastatin, and Atorvastatin in Healthy Adults.
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- Clinical Drug Investigation, 2021, v. 41, n. 2, p. 133, doi. 10.1007/s40261-020-00974-8
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- Article
Absorption of iothalamate after oral administration: A preliminary study in humans and interspecies differences.
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- Biopharmaceutics & Drug Disposition, 1987, v. 8, n. 1, p. 99, doi. 10.1002/bdd.2510080111
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- Publication type:
- Article
Absorption of iothalamate after oral administration and absorption enhancement by amino acids in dogs and rats.
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- Biopharmaceutics & Drug Disposition, 1986, v. 7, n. 5, p. 463, doi. 10.1002/bdd.2510070507
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- Publication type:
- Article
Renal and non-renal clearances of iothalamate.
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- Biopharmaceutics & Drug Disposition, 1986, v. 7, n. 4, p. 347, doi. 10.1002/bdd.2510070405
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- Publication type:
- Article
The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6.
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- British Journal of Clinical Pharmacology, 2003, v. 56, n. 1, p. 120, doi. 10.1046/j.1365-2125.2003.01833.x
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- Publication type:
- Article
Metabolic interactions between mibefradil and HMG-CoA reductase inhibitors: an in vitro investigation with human liver preparations.
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- British Journal of Clinical Pharmacology, 1999, v. 47, n. 3, doi. 10.1046/j.1365-2125.1999.00903.x
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- Publication type:
- Article
Simvastatin does not have a Clinically Significant Pharmacokinetic Interaction with Fenofibrate in Humans.
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- Journal of Clinical Pharmacology, 2004, v. 44, n. 9, p. 1054
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- Publication type:
- Article
Interactions between Simvastatin and Troglitazone or Pioglitazone in Healthy Subjects.
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- Journal of Clinical Pharmacology, 2001, v. 41, n. 5, p. 573, doi. 10.1177/00912700122010311
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- Publication type:
- Article
Simvastatin Does Not Affect CYP3A Activity, Quantified by the Erythromycin Breath Test and Oral Midazolam Pharmacokinetics, in Healthy Male Subjects.
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- Journal of Clinical Pharmacology, 2000, v. 40, n. 11, p. 1274, doi. 10.1177/009127000004001112
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- Publication type:
- Article
Concurrent Administration of the Erythromycin Breath Test (EBT) and Oral Midazolam as In Vivo Probes for CYP3A Activity.
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- Journal of Clinical Pharmacology, 1999, v. 39, n. 12, p. 1212, doi. 10.1177/009127009903901202
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- Publication type:
- Article
Immunopharmacodynamic Studies of Cyclosporine in Patients Awaiting Renal Transplantation.
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- 1995
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- Publication type:
- Other
Pharmacokinetics of Orally and Intravenously Administered Cyclosporine in Pre-Kidney Transplant Patients.
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- 1994
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- Publication type:
- Other
Assessing the relative contribution of CYP3A-and P-gp-mediated pathways to the overall disposition and drug-drug interaction of dabigatran etexilate using a comprehensive mechanistic physiological-based pharmacokinetic model.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1356273
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- Publication type:
- Article
Discovery of 5′′-Chloro- N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia.
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- ChemMedChem, 2014, v. 9, n. 2, p. 311, doi. 10.1002/cmdc.201300447
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- Publication type:
- Article
Cover Picture: Discovery of 5′′-Chloro- N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia (ChemMedChem 2/2014)
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- ChemMedChem, 2014, v. 9, n. 2, p. 241, doi. 10.1002/cmdc.201490000
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- Publication type:
- Article
Discovery of [(2 R,5 R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties.
- Published in:
- ChemMedChem, 2012, v. 7, n. 3, p. 415, doi. 10.1002/cmdc.201200025
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- Publication type:
- Article
Cover Picture: Discovery of [(2 R,5 R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties (ChemMedChem 3/2012).
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- ChemMedChem, 2012, v. 7, n. 3, p. 337, doi. 10.1002/cmdc.201290006
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- Publication type:
- Article
Discovery of a Potent, CNS-Penetrant Orexin Receptor Antagonist Based on an N, N-Disubstituted-1,4-diazepane Scaffold that Promotes Sleep in Rats.
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- ChemMedChem, 2009, v. 4, n. 7, p. 1069, doi. 10.1002/cmdc.200900069
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- Publication type:
- Article
The Impact of Glycosylation on the Pharmacokinetics of a TNFR2:Fc Fusion Protein Expressed in Glycoengineered Pichia Pastoris.
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- Pharmaceutical Research, 2013, v. 30, n. 3, p. 803, doi. 10.1007/s11095-012-0921-3
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- Publication type:
- Article
Theoretical Analysis of Interplay of Therapeutic Protein Drug and Circulating Soluble Target: Temporal Profiles of 'Free' and 'Total' Drug and Target.
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- Pharmaceutical Research, 2011, v. 28, n. 10, p. 2447, doi. 10.1007/s11095-011-0471-0
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- Publication type:
- Article
Use of In Vivo Animal Models to Assess Pharmacokinetic Drug-Drug Interactions.
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- Pharmaceutical Research, 2010, v. 27, n. 9, p. 1772, doi. 10.1007/s11095-010-0157-z
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- Publication type:
- Article