Works by Prokai-Tatrai, Katalin

Results: 46

The Prodrug DHED Delivers 17β-Estradiol into the Retina for Protection of Retinal Ganglion Cells and Preservation of Visual Function in an Animal Model of Glaucoma.

Published in:

Cells (2073-4409), 2024, v. 13, n. 13, p. 1126, doi. 10.3390/cells13131126

By:

Kapic, Ammar;
Zaman, Khadiza;
Nguyen, Vien;
Neagu, George C.;
Sumien, Nathalie;
Prokai, Laszlo;
Prokai-Tatrai, Katalin

Publication type:

Article

Proteomics-Based Retinal Target Engagement Analysis and Retina-Targeted Delivery of 17β-Estradiol by the DHED Prodrug for Ocular Neurotherapy in Males.

Published in:

Pharmaceutics, 2021, v. 13, n. 9, p. 1392, doi. 10.3390/pharmaceutics13091392

By:

Prokai-Tatrai, Katalin;
Zaman, Khadiza;
Nguyen, Vien;
De La Cruz, Daniel L.;
Prokai, Laszlo

Publication type:

Article

Retina-Targeted Delivery of 17β-Estradiol by the Topically Applied DHED Prodrug.

Published in:

Pharmaceutics, 2020, v. 12, n. 5, p. 456, doi. 10.3390/pharmaceutics12050456

By:

Prokai-Tatrai, Katalin;
Nguyen, Vien;
De La Cruz, Daniel L.;
Guerra, Rebecca;
Zaman, Khadiza;
Rahlouni, Fatima;
Prokai, Laszlo

Publication type:

Article

17β-Estradiol Delivered in Eye Drops: Evidence of Impact on Protein Networks and Associated Biological Processes in the Rat Retina through Quantitative Proteomics.

Published in:

Pharmaceutics, 2020, v. 12, n. 2, p. 101, doi. 10.3390/pharmaceutics12020101

By:

Prokai, Laszlo;
Zaman, Khadiza;
Nguyen, Vien;
Prokai-Tatrai, Katalin

Publication type:

Article

Brain Delivery of Thyrotropin-Releasing Hormone via a Novel Prodrug Approach.

Published in:

Pharmaceutics, 2019, v. 11, n. 7, p. 349, doi. 10.3390/pharmaceutics11070349

By:

Prokai-Tatrai, Katalin;
De La Cruz, Daniel L.;
Nguyen, Vien;
Ross, Benjamin P.;
Toth, Istvan;
Prokai, Laszlo

Publication type:

Article

Design and Exploratory Neuropharmacological Evaluation of Novel Thyrotropin-Releasing Hormone Analogs and Their Brain-Targeting Bioprecursor Prodrugs.

Published in:

Pharmaceutics, 2013, v. 5, n. 2, p. 318, doi. 10.3390/pharmaceutics5020318

By:

Prokai-Tatrai, Katalin;
Nguyen, Vien;
Szarka, Szabolcs;
Konya, Krisztina;
Prokai, Laszlo

Publication type:

Article

Identification of Estrogen-Responsive Proteins in Mouse Seminal Vesicles Through Mass Spectrometry-Based Proteomics.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 11, p. 1508, doi. 10.3390/ph17111508

By:

Kapic, Ammar;
Zaman, Khadiza;
Nguyen, Vien;
Prokai-Tatrai, Katalin;
Prokai, Laszlo

Publication type:

Article

Brain-Selective Estrogen Therapy Prevents Androgen Deprivation-Associated Hot Flushes in a Rat Model.

Published in:

Pharmaceuticals (14248247), 2020, v. 13, n. 6, p. 119, doi. 10.3390/ph13060119

By:

Merchenthaler, Istvan;
Lane, Malcolm;
Stennett, Christina;
Zhan, Min;
Nguyen, Vien;
Prokai-Tatrai, Katalin;
Prokai, Laszlo

Publication type:

Article

Patients with Subarachnoid Hemorrhage Exhibit Disturbed Expression Patterns of the Circadian Rhythm Gene Period-2.

Published in:

Life (2075-1729), 2021, v. 11, n. 2, p. 124, doi. 10.3390/life11020124

By:

Frase, Sibylle;
Kaiser, Sandra;
Steimer, Matti;
Selzner, Lisa;
Foit, Niels Alexander;
Niesen, Wolf-Dirk;
Schallner, Nils;
Prokai-Tatrai, Katalin

Publication type:

Article

Proteomics-Based Identification of Retinal Protein Networks Impacted by Elevated Intraocular Pressure in the Hypertonic Saline Injection Model of Experimental Glaucoma.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12592, doi. 10.3390/ijms241612592

By:

Zaman, Khadiza;
Nguyen, Vien;
Prokai-Tatrai, Katalin;
Prokai, Laszlo

Publication type:

Article

[β-Glu 2 ]TRH Is a Functional Antagonist of Thyrotropin-Releasing Hormone (TRH) in the Rodent Brain.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6230, doi. 10.3390/ijms22126230

By:

Prokai-Tatrai, Katalin;
Nguyen, Vien;
Prokai, Laszlo

Publication type:

Article

Proteomics Profiling of Neuron-Derived Small Extracellular Vesicles from Human Plasma: Enabling Single-Subject Analysis.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2951, doi. 10.3390/ijms22062951

By:

Anastasi, Federica;
Masciandaro, Silvia Maria;
Carratore, Renata Del;
Dell'Anno, Maria Teresa;
Signore, Giovanni;
Falleni, Alessandra;
McDonnell, Liam A.;
Bongioanni, Paolo;
Prokai-Tatrai, Katalin;
Balaj, Leonora

Publication type:

Article

Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1686, doi. 10.3390/ijms22041686

By:

Prokai, Laszlo;
Rahlouni, Fatima;
Zaman, Khadiza;
Nguyen, Vien;
Prokai-Tatrai, Katalin;
Schlüter, Hartmut

Publication type:

Article

Quantitative Structure-Activity Relationships Predicting the Antioxidant Potency of 17ß-Estradiol-Related Polycyclic Phenols to Inhibit Lipid Peroxidation.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 1, p. 1443, doi. 10.3390/ijms14011443

By:

Prokai, Laszlo;
Rivera-Portalatin, Nilka M.;
Prokai-Tatrai, Katalin

Publication type:

Article

Phenolic Compounds Protect Cultured Hippocampal Neurons against Ethanol-Withdrawal Induced Oxidative Stress.

Published in:

International Journal of Molecular Sciences, 2009, v. 10, n. 4, p. 1773, doi. 10.3390/ijms10041773

By:

Prokai-Tatrai, Katalin;
Prokai, Laszlo;
Simpkins, James W.;
Jung, Marianna E.

Publication type:

Article

The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders.

Published in:

Science Translational Medicine, 2015, v. 7, n. 297, p. 1, doi. 10.1126/scitranslmed.aab1290

By:

Prokai, Laszlo;
Vien Nguyen;
Szarka, Szabolcs;
Garg, Puja;
Sabnis, Gauri;
Bimonte-Nelson, Heather A.;
McLaughlin, Katie J.;
Talboom, Joshua S.;
Conrad, Cheryl D.;
Shughrue, Paul J.;
Gould, Todd D.;
Brodie, Angela;
Merchenthaler, Istvan;
Koulen, Peter;
Prokai-Tatrai, Katalin

Publication type:

Article

Exploratory pharmacokinetics and brain distribution study of a neuropeptide FF antagonist by liquid chromatography/atmospheric pressure ionization tandem mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2000, v. 14, n. 24, p. 2412, doi. 10.1002/1097-0231(20001230)14:24<2412::AID-RCM180>3.0.CO;2-3

By:

Prokai, Laszlo;
Zharikova, Alevtina D.;
Janáky§, Tamás;
Prokai-Tatrai, Katalin;
Ross, Charles

Publication type:

Article

PREPARATION OF O-(3,3,8,10,10-PENTAMETHYL-1,2-DITHIA-5,8-DIAZACYCLODECAN-5-YL)ETHYL O-PIVALOYLOXYMETHYL PHENYLPHOSPHONATE.

Published in:

Organic Preparations & Procedures International, 1998, v. 30, n. 4, p. 485, doi. 10.1080/00304949809355318

By:

Bodor, Nicholas;
Prokai-Tatrai, Katalin;
Koltai, Emo;
Prokai, Laszlo

Publication type:

Article

ANALOGS OF TRYPTOPHAN.

Published in:

Organic Preparations & Procedures International, 1994, v. 26, n. 6, p. 687, doi. 10.1080/00304949409458170

By:

Pop, Emil;
Prókai-Tátrai, Katalin;
Brewster, Marcus E.;
Bodor, Nicholas

Publication type:

Article

PREPARATION OF REDOX DERIVATIVES OF 3α-HYDROXY-5α-PREGNANE-11,20-DIONE.

Published in:

Organic Preparations & Procedures International, 1994, v. 26, n. 3, p. 379, doi. 10.1080/00304949409458444

By:

Pop, Emil;
Brewster, Marcus E.;
Prókai-Tátrai, Katalin;
Bodor, Nicholas

Publication type:

Article

Mass spectrometry‐based retina proteomics.

Published in:

Mass Spectrometry Reviews, 2023, v. 42, n. 3, p. 1032, doi. 10.1002/mas.21786

By:

Prokai, Laszlo;
Zaman, Khadiza;
Prokai‐Tatrai, Katalin

Publication type:

Article

Integration of mass spectrometry into early-phase discovery and development of central nervous system agents.

Published in:

Journal of Mass Spectrometry, 2001, v. 36, n. 11, p. 1211, doi. 10.1002/jms.227

By:

Prokai, Laszlo;
Zharikova, Alevtina;
Janáky, Tamás;
Li, Xiaoxu;
Braddy, April C.;
Perjési, Pál;
Matveeva, Lidia;
Powell, David H.;
Prokai-Tatrai, Katalin

Publication type:

Article

Impact of Metabolism on the Safety of Estrogen Therapy.

Published in:

Annals of the New York Academy of Sciences, 2005, v. 1052, n. 1, p. 243, doi. 10.1196/annals.1347.018

By:

PROKAI‐TATRAI, KATALIN;
PROKAI, LASZLO

Publication type:

Article

Mechanistic insights into the direct antioxidant effects of estrogens.

Published in:

Drug Development Research, 2005, v. 66, n. 2, p. 118, doi. 10.1002/ddr.20050

By:

Laszlo Prokai;
Katalin Prokai‐Tatrai;
Pál Perjési;
James W. Simpkins

Publication type:

Article

The impact of 17β-estradiol on the estrogen-deficient female brain: from mechanisms to therapy with hot flushes as target symptoms.

Published in:

Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2023.1310432

By:

Prokai-Tatrai, Katalin;
Prokai, Laszlo

Publication type:

Article

Targeting drugs to the brain by redox chemical delivery systems.

Published in:

Medicinal Research Reviews, 2000, v. 20, n. 5, p. 367, doi. 10.1002/1098-1128(200009)20:5<367::AID-MED3>3.0.CO;2-P

By:

Prokai, Laszlo;
Prokai-Tatrai, Katalin;
Bodor, Nicholas

Publication type:

Article

Selective chemoprecipitation to enrich nitropeptides from complex proteomes for mass-spectrometric analysis.

Published in:

Nature Protocols, 2014, v. 9, n. 4, p. 882, doi. 10.1038/nprot.2014.052

By:

Prokai, Laszlo;
Guo, Jia;
Prokai-Tatrai, Katalin

Publication type:

Article

Retina-Targeted 17β-Estradiol by the DHED Prodrug Rescues Visual Function and Actuates Neuroprotective Protein Networks After Optic Nerve Crush in a Rat Model of Surgical Menopause.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 5, p. 1846, doi. 10.3390/ijms26051846

By:

Prokai-Tatrai, Katalin;
Zaman, Khadiza;
Kapic, Ammar;
Hogan, Kelleigh;
Sanchez-Rodriguez, Gabriela;
Silverio, Anna E.;
Nguyen, Vien;
Prokai, Laszlo;
Feola, Andrew J.

Publication type:

Article

Separation of dansylated 17β-estradiol, 17α-estradiol, and estrone on a single HPLC column for simultaneous quantitation by LC-MS/MS.

Published in:

Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 10, p. 3399, doi. 10.1007/s00216-013-6710-y

By:

Szarka, Szabolcs;
Nguyen, Vien;
Prokai, Laszlo;
Prokai-Tatrai, Katalin

Publication type:

Article

The Antagonist pGlu-βGlu-Pro-NH 2 Binds to an Allosteric Site of the Thyrotropin-Releasing Hormone Receptor.

Published in:

Molecules, 2021, v. 26, n. 17, p. 5397, doi. 10.3390/molecules26175397

By:

De La Cruz, Daniel L.;
Prokai, Laszlo;
Prokai-Tatrai, Katalin

Publication type:

Article

Neuroprotective Effects and Mechanisms of Procyanidins In Vitro and In Vivo.

Published in:

Molecules, 2021, v. 26, n. 10, p. 2963, doi. 10.3390/molecules26102963

By:

Chen, Juan;
Chen, Yixuan;
Zheng, Yangfan;
Zhao, Jiawen;
Yu, Huilin;
Zhu, Jiajin;
Li, Duo;
Prokai-Tatrai, Katalin

Publication type:

Article

Synthesis, Anticonvulsant, and Antinociceptive Activity of New 3-(2-Chlorophenyl)- and 3-(3-Chlorophenyl)-2,5-dioxo-pyrrolidin-1-yl-acetamides.

Published in:

Molecules, 2021, v. 26, n. 6, p. 1564, doi. 10.3390/molecules26061564

By:

Góra, Małgorzata;
Czopek, Anna;
Rapacz, Anna;
Gębska, Anna;
Wójcik-Pszczoła, Katarzyna;
Pękala, Elżbieta;
Kamiński, Krzysztof;
Prokai-Tatrai, Katalin

Publication type:

Article

Covalent Histone Modification by an Electrophilic Derivative of the Anti-HIV Drug Nevirapine.

Published in:

Molecules, 2021, v. 26, n. 5, p. 1349, doi. 10.3390/molecules26051349

By:

Harjivan, Shrika G.;
Charneira, Catarina;
Martins, Inês L.;
Pereira, Sofia A.;
Espadas, Guadalupe;
Sabidó, Eduard;
Beland, Frederick A.;
Marques, M. Matilde;
Antunes, Alexandra M. M.;
de Sousa, Maria Emília;
Prokai-Tatrai, Katalin;
Gomes, Paula A. C.;
Galdiero, Stefania;
Gemma, Sandra;
Spetea, Mariana;
Roivainen, Anne

Publication type:

Article

From Combinations to Single-Molecule Polypharmacology—Cromolyn-Ibuprofen Conjugates for Alzheimer's Disease.

Published in:

Molecules, 2021, v. 26, n. 4, p. 1112, doi. 10.3390/molecules26041112

By:

Albertini, Claudia;
Naldi, Marina;
Petralla, Sabrina;
Strocchi, Silvia;
Grifoni, Daniela;
Monti, Barbara;
Bartolini, Manuela;
Bolognesi, Maria Laura;
Sousa, Maria Emília de;
Prokai-Tatrai, Katalin;
Gomes, Paula A. C.;
Galdiero, Stefania;
Gemma, Sandra;
Spetea, Mariana;
Roivainen, Anne

Publication type:

Article

New Antineoplastic Naphthohydroquinones Attached to Labdane and Rearranged Diterpene Skeletons.

Published in:

Molecules, 2021, v. 26, n. 2, p. 474, doi. 10.3390/molecules26020474

By:

Hernández, Ángela P.;
Chamorro, Pablo;
Rodríguez, Mª Lucena;
Miguel del Corral, José M.;
García, Pablo A.;
Francesch, Andrés;
San Feliciano, Arturo;
Castro, Mª Ángeles;
de Sousa, Maria Emília;
Prokai-Tatrai, Katalin;
Gomes, Paula A. C.;
Galdiero, Stefania;
Gemma, Sandra;
Spetea, Mariana;
Roivainen, Anne

Publication type:

Article

Modulating Protein–Protein Interactions by Cyclic and Macrocyclic Peptides. Prominent Strategies and Examples.

Published in:

Molecules, 2021, v. 26, n. 2, p. 445, doi. 10.3390/molecules26020445

By:

González-Muñiz, Rosario;
Bonache, María Ángeles;
Pérez de Vega, María Jesús;
de Sousa, Maria Emília;
Prokai-Tatrai, Katalin;
Gomes, Paula A. C.;
Galdiero, Stefania;
Gemma, Sandra;
Spetea, Mariana;
Roivainen, Anne

Publication type:

Article

Nucleophilic Synthesis of 6-l-[18F]FDOPA. Is Copper-Mediated Radiofluorination the Answer?

Published in:

Molecules, 2020, v. 25, n. 19, p. 4365, doi. 10.3390/molecules25194365

By:

Krasikova, Raisa N.;
de Sousa, Maria Emília;
Prokai-Tatrai, Katalin;
Gomes, Paula A. C.;
Galdiero, Stefania;
Gemma, Sandra;
Spetea, Mariana;
Roivainen, Anne

Publication type:

Article

Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore.

Published in:

Molecules, 2020, v. 25, n. 18, p. 4260, doi. 10.3390/molecules25184260

By:

Sarkar, Arijit;
Adamska-Bartlomiejczyk, Anna;
Piekielna-Ciesielska, Justyna;
Wtorek, Karol;
Kluczyk, Alicja;
Borics, Attila;
Janecka, Anna;
Sousa, Maria Emília de;
Prokai-Tatrai, Katalin;
Gomes, Paula A. C.;
Galdiero, Stefania;
Gemma, Sandra;
Spetea, Mariana;
Roivainen, Anne

Publication type:

Article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7.

Published in:

2020

By:

Gütschow, Michael;
Vanden Eynde, Jean Jacques;
Jampilek, Josef;
Kang, CongBao;
Mangoni, Arduino A.;
Fossa, Paola;
Karaman, Rafik;
Trabocchi, Andrea;
Scott, Peter J. H.;
Reynisson, Jóhannes;
Rapposelli, Simona;
Galdiero, Stefania;
Winum, Jean-Yves;
Brullo, Chiara;
Prokai-Tatrai, Katalin;
Sharma, Arun K.;
Schapira, Matthieu;
Azuma, Yasu-Taka;
Cerchia, Laura;
Spetea, Mariana

Publication type:

Editorial

A Novel Prodrug Approach for Central Nervous System-Selective Estrogen Therapy.

Published in:

Molecules, 2019, v. 24, n. 22, p. 4197, doi. 10.3390/molecules24224197

By:

Prokai-Tatrai, Katalin;
Prokai, Laszlo;
Muñoz-Torrero, Diego;
Luque, F. Javier;
Pastor-Anglada, Marçal;
Minutolo, Filippo

Publication type:

Article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–5.

Published in:

Molecules, 2019, v. 24, n. 13, p. 2415, doi. 10.3390/molecules24132415

By:

Mangoni, Arduino A.;
Eynde, Jean Jacques Vanden;
Jampilek, Josef;
Hadjipavlou-Litina, Dimitra;
Liu, Hong;
Reynisson, Jóhannes;
Sousa, Maria Emília;
Gomes, Paula A. C.;
Prokai-Tatrai, Katalin;
Tuccinardi, Tiziano;
Sabatier, Jean-Marc;
Luque, F. Javier;
Rautio, Jarkko;
Karaman, Rafik;
Vasconcelos, M. Helena;
Gemma, Sandra;
Galdiero, Stefania;
Hulme, Christopher;
Collina, Simona;
Gütschow, Michael

Publication type:

Article

Protective Effects of a New C-Jun N-terminal Kinase Inhibitor in the Model of Global Cerebral Ischemia in Rats.

Published in:

Molecules, 2019, v. 24, n. 9, p. 1722, doi. 10.3390/molecules24091722

By:

Plotnikov, Mark B.;
Chernysheva, Galina A.;
Aliev, Oleg I.;
Smol'iakova, Vera I.;
Fomina, Tatiana I.;
Osipenko, Anton N.;
Rydchenko, Victoria S.;
Anfinogenova, Yana J.;
Khlebnikov, Andrei I.;
Schepetkin, Igor A.;
Atochin, Dmitriy N.;
Prokai-Tatrai, Katalin

Publication type:

Article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–4.

Published in:

2019

By:

Mangoni, Arduino A;
Guillou, Catherine;
Vanden Eynde, Jean Jacques;
Hulme, Christopher;
Jampilek, Josef;
Li, Wei;
Prokai-Tatrai, Katalin;
Rautio, Jarkko;
Collina, Simona;
Tuccinardi, Tiziano;
Sousa, Maria Emília;
Sabatier, Jean-Marc;
Galdiero, Stefania;
Karaman, Rafik;
Kokotos, George;
Torri, Giangiacomo;
Luque, F. Javier;
Vasconcelos, M. Helena;
Hadjipavlou-Litina, Dimitra;
Siciliano, Carlo

Publication type:

Editorial

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3.

Published in:

Molecules, 2018, v. 23, n. 7, p. 1596, doi. 10.3390/molecules23071596

By:

Mangoni, Arduino A.;
Tuccinardi, Tiziano;
Collina, Simona;
Vanden Eynde, Jean Jacques;
Muñoz-Torrero, Diego;
Karaman, Rafik;
Siciliano, Carlo;
de Sousa, Maria Emília;
Prokai-Tatrai, Katalin;
Rautio, Jarkko;
Guillou, Catherine;
Gütschow, Michael;
Galdiero, Stefania;
Hong Liu;
Agrofoglio, Luigi A.;
Sabatier, Jean-Marc;
Hulme, Christopher;
Kokotos, George;
Qong You;
Gomes, Paula A. C.

Publication type:

Article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-2.

Published in:

Molecules, 2018, v. 23, n. 1, p. 65, doi. 10.3390/molecules23010065

By:

Muñoz-Torrero, Diego;
Mangoni, Arduino A.;
Liu, Hong;
Hulme, Christopher;
Rautio, Jarkko;
Karaman, Rafik;
de Sousa, Maria Emília;
Prokai-Tatrai, Katalin;
Sabatier, Jean-Marc;
Siciliano, Carlo;
Luque, F. Javier;
Kokotos, George;
Ragno, Rino;
Collina, Simona;
Guillou, Catherine;
Gütschow, Michael;
Agrofoglio, Luigi A.

Publication type:

Article

Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery.

Published in:

Scientific Reports, 2016, p. 30721, doi. 10.1038/srep30721

By:

Merchenthaler, Istvan;
Lane, Malcolm;
Sabnis, Gauri;
Brodie, Angela;
Nguyen, Vien;
Prokai, Laszlo;
Prokai-Tatrai, Katalin

Publication type:

Article