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Understanding inflammation in juvenile idiopathic arthritis: How immune biomarkers guide clinical strategies in the systemic onset subtype.
Published in:
European Journal of Immunology, 2016, v. 46, n. 9, p. 2068, doi. 10.1002/eji.201546092
By:
- Swart, Joost F.;
- Roock, Sytze;
- Prakken, Berent J.
Publication type:
Article
FOXP3.
Published in:
European Journal of Immunology, 2011, v. 41, n. 4, p. 1132, doi. 10.1002/eji.201040363
By:
- Schadenberg, Alvin W. L.;
- Vastert, Sebastiaan J.;
- Evens, Fabiola C. M.;
- Kuis, Wietse;
- van Vught, Adrianus J.;
- Jansen, Nicolaas J. G.;
- Prakken, Berent J.
Publication type:
Article
Tolerance to an Arthritogenic T-cell Epitope of HSP65 and the Regulation of Experimental Arthritis.
Published in:
Annals of the New York Academy of Sciences, 1996, v. 778, n. 1, p. 425, doi. 10.1111/j.1749-6632.1996.tb21163.x
By:
- PRAKKEN, BERENT J.;
- ZEE, RUURD;
- ANDERTON, STEPHEN M.;
- KOOTEN, PETER;
- KUIS, WIETSE;
- EDEN, WILLEM
Publication type:
Article
Novel pan-DR-binding T cell epitopes of adenovirus induce pro-inflammatory cytokines and chemokines in healthy donors.
Published in:
International Immunology, 2006, v. 18, n. 11, p. 1521, doi. 10.1093/intimm/dxl085
By:
- Haveman, Lianne M.;
- Bierings, Marc;
- Legger, Elisabeth;
- Klein, Mark R.;
- de Jager, Wilco;
- Otten, Henny G.;
- Albani, Salvatore;
- Kuis, Wietse;
- Sette, Alessandro;
- Prakken, Berent J.
Publication type:
Article
Establishing an international awareness day for paediatric rheumatic diseases: reflections from the inaugural World Young Rheumatic Diseases (WORD) Day 2019.
Published in:
2020
By:
- Smith, Eve M. D.;
- Ainsworth, Sammy;
- Beresford, Michael W.;
- Buys, Veerle;
- Costello, Wendy;
- Egert, Yona;
- Foster, Helen E.;
- Lamot, Lovro;
- Prakken, Berent J.;
- Scott, Christiaan;
- Stones, Simon R.
Publication type:
Letter
How a four-year-old boy connects healthcare, biomedical research and undergraduate education.
Published in:
Nature Biotechnology, 2019, v. 37, n. 9, p. 1092, doi. 10.1038/s41587-019-0245-5
By:
- Drost, Rijkent H.;
- Dictus, Wim J. A. G.;
- Prakken, Berent J.;
- Bovenschen, Niels
Publication type:
Article
Increased Presence of FOXP3+ Regulatory T Cells in Inflamed Muscle of Patients with Active Juvenile Dermatomyositis Compared to Peripheral Blood.
Published in:
PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105353
By:
- Vercoulen, Yvonne;
- Bellutti Enders, Felicitas;
- Meerding, Jenny;
- Plantinga, Maud;
- Elst, Elisabeth F.;
- Varsani, Hemlata;
- van Schieveen, Christa;
- Bakker, Mette H.;
- Klein, Mark;
- Scholman, Rianne C.;
- Spliet, Wim;
- Ricotti, Valeria;
- Koenen, Hans J. P. M.;
- de Weger, Roel A.;
- Wedderburn, Lucy R.;
- van Royen-Kerkhof, Annet;
- Prakken, Berent J.
Publication type:
Article
STAT3 Regulates Monocyte TNF-Alpha Production in Systemic Inflammation Caused by Cardiac Surgery with Cardiopulmonary Bypass.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035070
By:
- Jong, Petrus R. de;
- Schadenberg, Alvin W. L.;
- van den Broek, Theo;
- Beekman, Jeffrey M.;
- van Wijk, Femke;
- Coffer, Paul J.;
- Prakken, Berent J.;
- Jansen, Nicolaas J. G.
Publication type:
Article
Cord Blood CD4+ T Cells Respond to Self Heat Shock Protein 60 (HSP60).
Published in:
PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024119
By:
- Aalberse, Joost A.;
- Kapitein, Berber;
- de Roock, Sytze;
- Klein, Mark R.;
- de Jager, Wilco;
- van der Zee, Ruurd;
- Hoekstra, Maarten O.;
- van Wijk, Femke;
- Prakken, Berent J.
Publication type:
Article
Human Regulatory T Cell Suppressive Function Is Independent of Apoptosis Induction in Activated Effector T Cells.
Published in:
PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0007183
By:
- Vercoulen, Yvonne;
- Wehrens, Ellen J.;
- van Teijlingen, Nienke H.;
- de Jager, Wilco;
- Beekman, Jeffrey M.;
- Prakken, Berent J.
Publication type:
Article
Heat shock protein 60 and adjuvant arthritis: a model for T cell regulation in human arthritis.
Published in:
Springer Seminars in Immunopathology, 2003, v. 25, n. 1, p. 47, doi. 10.1007/s00281-003-0128-7
By:
- Prakken, Berent J.;
- Roord, Sarah;
- Ronaghy, Arash;
- Wauben, Marca;
- Albani, Salvatore;
- van Eden, Willern
Publication type:
Article
Different cytokine signatures in children with localized and invasive adenovirus infection after stem cell transplantation.
Published in:
Pediatric Transplantation, 2010, v. 14, n. 4, p. 520, doi. 10.1111/j.1399-3046.2009.01263.x
By:
- Haveman, Lianne M.;
- de Jager, Wilco;
- van Loon, Anton M.;
- Claas, Eric C. J.;
- Prakken, Berent J.;
- Bierings, Marc
Publication type:
Article
Heat-shock protein T-cell epitopes trigger a spreading regulatory control in a diversified arthritogenic T-cell response.
Published in:
Immunological Reviews, 1998, v. 164, n. 1, p. 169, doi. 10.1111/j.1600-065X.1998.tb01218.x
By:
- van Eden, Willen;
- van der Zee, Ruurd;
- Taams, Leonie S.;
- Prakken, A. Berent J.;
- van Roon, Joel;
- Wauben, Marca H.M.
Publication type:
Article
A Multiplex Immunoassay for Human Adipokine Profiling.
Published in:
Clinical Chemistry, 2010, v. 56, n. 8, p. 1320, doi. 10.1373/clinchem.2010.146118
By:
- Schipper, Henk S.;
- de Jager, Wilco;
- van Dijk, Mariska E. A.;
- Meerding, Jenny;
- Zelissen, Pierre M. J.;
- Adan, Roger A.;
- Prakken, Berent J.;
- Kalkhoven, Eric
Publication type:
Article
PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation.
Published in:
2018
By:
- Petrelli, Alessandra;
- Mijnheer, Gerdien;
- Hoytema van Konijnenburg, David P.;
- van der Wal, Maria M.;
- Giovannone, Barbara;
- Mocholi, Enric;
- Vazirpanah, Nadia;
- Broen, Jasper C.;
- Hijnen, Dirkjan;
- Oldenburg, Bas;
- Coffer, Paul J.;
- Vastert, Sebastian J.;
- Prakken, Berent J.;
- Spierings, Eric;
- Pandit, Aridaman;
- Mokry, Michal;
- van Wijk, Femke;
- van Konijnenburg, David P Hoytema
Publication type:
journal article
Neonatal thymectomy reveals differentiation and plasticity within human naive T cells.
Published in:
2016
By:
- van den Broek, Theo;
- Delemarre, Eveline M.;
- Janssen, Willemijn J. M.;
- Nievelstein, Rutger A. J.;
- Broen, Jasper C.;
- Tesselaar, Kiki;
- Borghans, Jose A. M.;
- Nieuwenhuis, Edward E. S.;
- Prakken, Berent J.;
- Mokry, Michal;
- Jansen, Nicolaas J. G.;
- van Wijk, Femke
Publication type:
journal article
Methotrexate treatment affects effector but not regulatory T cells in juvenile idiopathic arthritis.
Published in:
Rheumatology, 2015, v. 54, n. 9, p. 1724, doi. 10.1093/rheumatology/kev101
By:
- Bulatović Ćalasan, Maja;
- Vastert, Sebastiaan J.;
- Scholman, Rianne C.;
- Verweij, Frederik;
- Klein, Mark;
- Wulffraat, Nico M.;
- Prakken, Berent J.;
- van Wijk, Femke
Publication type:
Article
Treating arthritis by immunomodulation: is there a role for regulatory T cells?
Published in:
Rheumatology, 2010, v. 49, n. 9, p. 1632, doi. 10.1093/rheumatology/keq130
By:
- Wehrens, Ellen J.;
- Wijk, Femke van;
- Roord, Sarah T.;
- Albani, Salvatore;
- Prakken, Berent J.
Publication type:
Article
Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis.
Published in:
Rheumatology, 2010, v. 49, n. 3, p. 441, doi. 10.1093/rheumatology/kep418
By:
- Vastert, Sebastiaan J.;
- Van Wijk, Richard;
- D'Urbano, Leila E.;
- De Vooght, Karen M. K.;
- De Jager, Wilco;
- Ravelli, Angelo;
- Magni-Manzoni, Silvia;
- Insalaco, Antonella;
- Cortis, Elisabetta;
- Van Solinge, Wouter W.;
- Prakken, Berent J.;
- Wulffraat, Nico M.;
- De Benedetti, Fabrizio;
- Kuis, Wietse
Publication type:
Article
Differential cytokine profiles in juvenile idiopathic arthritis subtypes revealed by cluster analysis.
Published in:
Rheumatology, 2009, v. 48, n. 8, p. 899, doi. 10.1093/rheumatology/kep125
By:
- Ham, Henk-Jan van den;
- De Jager, Wilco;
- Bijlsma, Johannes W. J.;
- Prakken, Berent J.;
- De Boer, Rob J.
Publication type:
Article
Plasma chemokines in early wheezers predict the development of allergic asthma.
Published in:
2013
By:
- Reubsaet, Lieke L;
- Meerding, Jenny;
- de Jager, Wilco;
- de Kleer, Isme M;
- Hoekstra, Maarten O;
- Prakken, Berent J;
- van Wijk, Femke;
- Arets, Hubertus G
Publication type:
Journal Article
Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune Disorders.
Published in:
Frontiers in Immunology, 2016, v. 7, p. 1, doi. 10.3389/fimmu.2016.00587
By:
- te Velde, Anje A.;
- Bezema, Tjitske;
- van Kampen, Antoine H. C.;
- Kraneveld, Aletta D.;
- ť Hart, Bert A.;
- Middendorp, Henriët van;
- Hack, Erik C.;
- van Montfrans, Joris M.;
- Belzer, Clara;
- Jans-Beken, Lilian;
- Pieters, Raymond H.;
- Knipping, Karen;
- Huber, Machteld;
- H. Boots, Annemieke M.;
- Garssen, Johan;
- Radstake, Tim R.;
- M. Evers, Andrea W.;
- Prakken, Berent J.;
- Joosten, Irma
Publication type:
Article
Developing translational medicine professionals: the Marie Skłodowska-Curie action model.
Published in:
2016
By:
- Petrelli, Alessandra;
- Prakken, Berent J;
- Rosenblum, Norman D;
- EUtrain fellows
Publication type:
journal article
Developing translational medicine professionals: the Marie Skłodowska-Curie action model.
Published in:
Journal of Translational Medicine, 2016, v. 14, p. 1, doi. 10.1186/s12967-016-1088-1
By:
- Petrelli, Alessandra;
- Prakken, Berent J.;
- Rosenblum, Norman D.
Publication type:
Article
IL-1 receptor antagonist restores IL-18 NK cell axis in systemic JIA.
Published in:
2012
By:
- Vastert, Sebastiaan J.;
- De Jager, Wilco;
- Noordman, Bo Jan;
- Prakken, Berent J.;
- Wulffraat, Nico M.
Publication type:
Abstract
Self-Sustained Resistance to Suppression of CD8+ Teff Cells at the Site of Autoimmune Inflammation Can Be Reversed by Tumor Necrosis Factor and Interferon-γ Blockade.
Published in:
Arthritis & Rheumatology, 2016, v. 68, n. 1, p. 229, doi. 10.1002/art.39418
By:
- Petrelli, Alessandra;
- Wehrens, Ellen J.;
- Scholman, Rianne C.;
- Prakken, Berent J.;
- Vastert, Sebastian J.;
- van Wijk, Femke
Publication type:
Article
Effectiveness of First-Line Treatment With Recombinant Interleukin-1 Receptor Antagonist in Steroid-Naive Patients With New-Onset Systemic Juvenile Idiopathic Arthritis: Results of a Prospective Cohort Study.
Published in:
Arthritis & Rheumatology, 2014, v. 66, n. 4, p. 1034, doi. 10.1002/art.38296
By:
- Vastert, Sebastiaan J.;
- Jager, Wilco;
- Noordman, Bo Jan;
- Holzinger, Dirk;
- Kuis, Wietse;
- Prakken, Berent J.;
- Wulffraat, Nico M.
Publication type:
Article
Brief Report: Autologous Stem Cell Transplantation Restores Immune Tolerance in Experimental Arthritis by Renewal and Modulation of the Teff Cell Compartment.
Published in:
Arthritis & Rheumatology, 2014, v. 66, n. 2, p. 350, doi. 10.1002/art.38261
By:
- Delemarre, Eveline M.;
- Roord, Sarah T. A.;
- Broek, Theo;
- Zonneveld‐Huijssoon, Evelien;
- Jager, Wilco;
- Rozemuller, Henk;
- Martens, Anton C.;
- Broere, Femke;
- Wulffraat, Nico M.;
- Glant, Tibor T.;
- Prakken, Berent J.;
- Wijk, Femke
Publication type:
Article
CD4+FOXP3+ regulatory T cells are abundantly present in inflamed muscle of patients with juvenile dermatomyositis.
Published in:
2011
By:
- Vercoulen, Yvonne;
- Elst, Elisabeth F.;
- Meerding, Jenny;
- Plantinga, Maud;
- Varsani, Hemlata;
- van Schieveen, Christa;
- Bakker, Mette H.;
- Klein, Mark;
- Spliet, Wim;
- de Weger, R.;
- Wedderburn, Lucy;
- van Royen-Kerkhof, Annet;
- Prakken, Berent J.
Publication type:
Abstract
PD-1/PD-L1 signaling in JIA synovial regulatory T cell function.
Published in:
2011
By:
- de Roock, Sytze;
- Keustermans, Genoveva;
- Duurland, Chantal L.;
- Wehrens, Ellen J. M.;
- Wijk, Femke van;
- Prakken, Berent J.
Publication type:
Abstract
CD4+FOXP3+ regulatory T cells are abundantly present in inflamed muscle of patients with juvenile dermatomyositis.
Published in:
2011
By:
- Vercoulen, Yvonne;
- Elst, Elisabeth F.;
- Meerding, Jenny;
- Plantinga, Maud;
- Varsani, Hemlata;
- Schieveen, Christa van;
- Bakker, Mette H.;
- Klein, Mark;
- Spliet, Wim;
- Weger, R. de;
- Wedderburn, Lucy;
- Royen-Kerkhof, Annet van;
- Prakken, Berent J.
Publication type:
Abstract
Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery.
Published in:
Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-24
By:
- Algra, Selma O.;
- Groeneveld, Kathelijne M.;
- Schadenberg, Alvin W. L.;
- Haas, Felix;
- Evens, Fabiola C. M.;
- Meerding, Jenny;
- Koenderman, Leo;
- Jansen, Nicolaas J. G.;
- Prakken, Berent J.
Publication type:
Article
Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery.
Published in:
2013
By:
- Algra, Selma O;
- Groeneveld, Kathelijne M;
- Schadenberg, Alvin Wl;
- Haas, Felix;
- Evens, Fabiola Cm;
- Meerding, Jenny;
- Koenderman, Leo;
- Jansen, Nicolaas Jg;
- Prakken, Berent J;
- Schadenberg, Alvin W L;
- Evens, Fabiola C M;
- Jansen, Nicolaas J G
Publication type:
journal article
International online mentorship for translational researchers.
Published in:
BMC Medical Education, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12909-024-06107-5
By:
- Kools, Farah R. W.;
- Fox, Christine M.;
- van Rijen, Harold V. M.;
- Prakken, Berent J.
Publication type:
Article
Redefining strategies to introduce tolerance inducing cellular therapy in humans to combat autoimmunity and transplantation reactions.
Published in:
Frontiers in Immunology, 2014, v. 5, p. 1, doi. 10.3389/fimmu.2014.00392
By:
- ten Brinke, Anja;
- Joosten, Irma;
- van Ham, S. Marieke;
- van Kooten, Cees;
- Prakken, Berent J.
Publication type:
Article
HSP: bystander antigen in atopic diseases?
Published in:
Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00139
By:
- Aalberse, Joost A.;
- Prakken, Berent J.;
- Kapitein, Berber
Publication type:
Article
Translating immunological tolerance into therapy.
Published in:
European Journal of Immunology, 2007, v. 37, n. 9, p. 2360, doi. 10.1002/eji.200790036
By:
- Prakken, Berent J.;
- Albani, Salvatore;
- van Eden, Willem
Publication type:
Article

Found: 37

Understanding inflammation in juvenile idiopathic arthritis: How immune biomarkers guide clinical strategies in the systemic onset subtype.

FOXP3.

Tolerance to an Arthritogenic T-cell Epitope of HSP65 and the Regulation of Experimental Arthritis.

Novel pan-DR-binding T cell epitopes of adenovirus induce pro-inflammatory cytokines and chemokines in healthy donors.

Establishing an international awareness day for paediatric rheumatic diseases: reflections from the inaugural World Young Rheumatic Diseases (WORD) Day 2019.

How a four-year-old boy connects healthcare, biomedical research and undergraduate education.

Increased Presence of FOXP3<sup>+</sup> Regulatory T Cells in Inflamed Muscle of Patients with Active Juvenile Dermatomyositis Compared to Peripheral Blood.

STAT3 Regulates Monocyte TNF-Alpha Production in Systemic Inflammation Caused by Cardiac Surgery with Cardiopulmonary Bypass.

Cord Blood CD4<sup>+</sup> T Cells Respond to Self Heat Shock Protein 60 (HSP60).

Human Regulatory T Cell Suppressive Function Is Independent of Apoptosis Induction in Activated Effector T Cells.

Heat shock protein 60 and adjuvant arthritis: a model for T cell regulation in human arthritis.

Different cytokine signatures in children with localized and invasive adenovirus infection after stem cell transplantation.

Heat-shock protein T-cell epitopes trigger a spreading regulatory control in a diversified arthritogenic T-cell response.

A Multiplex Immunoassay for Human Adipokine Profiling.

PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation.

Neonatal thymectomy reveals differentiation and plasticity within human naive T cells.

Methotrexate treatment affects effector but not regulatory T cells in juvenile idiopathic arthritis.

Treating arthritis by immunomodulation: is there a role for regulatory T cells?

Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis.

Differential cytokine profiles in juvenile idiopathic arthritis subtypes revealed by cluster analysis.

Plasma chemokines in early wheezers predict the development of allergic asthma.

Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune Disorders.

Developing translational medicine professionals: the Marie Skłodowska-Curie action model.

Developing translational medicine professionals: the Marie Skłodowska-Curie action model.

IL-1 receptor antagonist restores IL-18 NK cell axis in systemic JIA.

Self-Sustained Resistance to Suppression of CD8+ Teff Cells at the Site of Autoimmune Inflammation Can Be Reversed by Tumor Necrosis Factor and Interferon-γ Blockade.

Effectiveness of First-Line Treatment With Recombinant Interleukin-1 Receptor Antagonist in Steroid-Naive Patients With New-Onset Systemic Juvenile Idiopathic Arthritis: Results of a Prospective Cohort Study.

Brief Report: Autologous Stem Cell Transplantation Restores Immune Tolerance in Experimental Arthritis by Renewal and Modulation of the Teff Cell Compartment.

CD4<sup>+</sup>FOXP3<sup>+</sup> regulatory T cells are abundantly present in inflamed muscle of patients with juvenile dermatomyositis.

PD-1/PD-L1 signaling in JIA synovial regulatory T cell function.

CD4<sup>+</sup>FOXP3<sup>+</sup> regulatory T cells are abundantly present in inflamed muscle of patients with juvenile dermatomyositis.

Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery.

Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery.

International online mentorship for translational researchers.

Redefining strategies to introduce tolerance inducing cellular therapy in humans to combat autoimmunity and transplantation reactions.

HSP: bystander antigen in atopic diseases?

Translating immunological tolerance into therapy.