Works by Pradhan, Sriharsa

Results: 47

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 1, p. 42, doi. 10.1038/nsmb.1939

By:

Estève, Pierre-Olivier;
Yanqi Chang;
Samaranayake, Mala;
Upadhyay, Anup K;
Horton, John R;
Feehery, George R;
Xiaodong Cheng;
Pradhan, Sriharsa

Publication type:

Article

HP1-mediated silencing targets Pol II coactivator complexes.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 3, p. 318, doi. 10.1038/nsmb.1385

By:

Smallwood, Andrea;
Black, Joshua C.;
Tanese, Naoko;
Pradhan, Sriharsa;
Carey, Michael

Publication type:

Article

Polyglutamylation: biology and analysis.

Published in:

Amino Acids, 2022, v. 54, n. 4, p. 529, doi. 10.1007/s00726-022-03146-4

By:

Ruse, Cristian I.;
Chin, Hang Gyeong;
Pradhan, Sriharsa

Publication type:

Article

Mechanisms of DNA Methyltransferase Recruitment in Mammals.

Published in:

Genes, 2018, v. 9, n. 12, p. 617, doi. 10.3390/genes9120617

By:

Laisné, Marthe;
Gupta, Nikhil;
Kirsh, Olivier;
Pradhan, Sriharsa;
Defossez, Pierre-Antoine

Publication type:

Article

Mammalian epigenetic mechanisms.

Published in:

IUBMB Life, 2014, v. 66, n. 4, p. 240, doi. 10.1002/iub.1264

By:

Zhang, Guoqiang;
Pradhan, Sriharsa

Publication type:

Article

DNA methylation and differentiation: HOX genes in muscle cells.

Published in:

Epigenetics & Chromatin, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8935-6-25

By:

Tsumagari, Koji;
Baribault, Carl;
Terragni, Jolyon;
Chandra, Sruti;
Renshaw, Chloe;
Sun, Zhiyi;
Song, Lingyun;
Crawford, Gregory E.;
Pradhan, Sriharsa;
Lacey, Michelle;
Ehrlich, Melanie

Publication type:

Article

A Method for Selectively Enriching Microbial DNA from Contaminating Vertebrate Host DNA.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076096

By:

Feehery, George R.;
Yigit, Erbay;
Oyola, Samuel O.;
Langhorst, Bradley W.;
Schmidt, Victor T.;
Stewart, Fiona J.;
Dimalanta, Eileen T.;
Amaral-Zettler, Linda A.;
Davis, Theodore;
Quail, Michael A.;
Pradhan, Sriharsa

Publication type:

Article

The Human Proteins MBD5 and MBD6 Associate with Heterochromatin but They Do Not Bind Methylated DNA.

Published in:

PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0011982

By:

Laget, Sophie;
Joulie, Michael;
Masson, Florent Le;
Sasai, Nobuhiro;
Christians, Elisabeth;
Pradhan, Sriharsa;
Roberts, Richard J.;
Defossez, Pierre-Antoine

Publication type:

Article

Inhibition of poly(ADP‐ribosyl)ation induces DNA hypermethylation: a possible molecular mechanism.

Published in:

FASEB Journal, 2002, v. 16, n. 10, p. 1319, doi. 10.1096/fj.01-0827fje

By:

Zardo, Giuseppe;
Reale, Anna;
Passananti, Claudio;
Pradhan, Sriharsa;
Buontempo, Serena;
De Matteis, Giovanna;
Adams, Roger L.P.;
Caiafa, Paola

Publication type:

Article

PKC isoforms interact with and phosphorylate DNMT1.

Published in:

BMC Biology, 2011, v. 9, n. 1, p. 31, doi. 10.1186/1741-7007-9-31

By:

Lavoie, Geneviève;
Estève, Pierre-Olivier;
Laulan, Nathalie Bibens;
Pradhan, Sriharsa;
St-Pierre, Yves

Publication type:

Article

Tissue-specific epigenetics in gene neighborhoods: myogenic transcription factor genes.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 16, p. 4660, doi. 10.1093/hmg/ddv198

By:

Chandra, Sruti;
Terragni, Jolyon;
Guoqiang Zhang;
Pradhan, Sriharsa;
Haushka, Stephen;
Johnston, Douglas;
Baribault, Carl;
Lacey, Michelle;
Ehrlich, Melanie

Publication type:

Article

One-pot universal NicE-seq: all enzymatic downstream processing of 4% formaldehyde crosslinked cells for chromatin accessibility genomics.

Published in:

Epigenetics & Chromatin, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13072-021-00427-2

By:

Vishnu, Udayakumar S.;
Estève, Pierre-Olivier;
Chin, Hang Gyeong;
Pradhan, Sriharsa

Publication type:

Article

5-Aza-2′-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression.

Published in:

International Journal of Cancer, 2011, v. 129, n. 9, p. 2083, doi. 10.1002/ijc.25865

By:

Couillard, Julie;
Estève, Pierre-Olivier;
Pradhan, Sriharsa;
St-Pierre, Yves

Publication type:

Article

Levels of DNA cytosine methylation in the Drosophila genome.

Published in:

PeerJ, 2018, p. 1, doi. 10.7717/peerj.5119

By:

Deshmukh, Saniya;
Ponnaluri, V. K. Chaithanya;
Dai, Nan;
Pradhan, Sriharsa;
Deobagkar, Deepti

Publication type:

Article

Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases.

Published in:

EMBO Journal, 2002, v. 21, n. 15, p. 4183, doi. 10.1093/emboj/cdf401

By:

Kim, Gun-Do;
Ni, Jingwei;
Kelesoglu, Nicole;
Robert, Richard J.;
Pradhan, Sriharsa

Publication type:

Article

The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity.

Published in:

EMBO Journal, 2002, v. 21, n. 4, p. 779, doi. 10.1093/emboj/21.4.779

By:

Pradhan, Sriharsa;
Gun-Do Kim

Publication type:

Article

Hybrid mouse-prokaryotic DNA (cytosine-5) methyltransferases retain the specificity of the parental C-terminal domain.

Published in:

EMBO Journal, 2000, v. 19, n. 9, p. 2103, doi. 10.1093/emboj/19.9.2103

By:

Pradhan, Sriharsa;
Roberts, Richard J.

Publication type:

Article

Poly ADP-ribosylation of SET8 leads to aberrant H4K20 methylation in mammalian nuclear genome.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04241-8

By:

Estève, Pierre-Olivier;
Sen, Sagnik;
Vishnu, Udayakumar S.;
Ruse, Cristian;
Chin, Hang Gyeong;
Pradhan, Sriharsa

Publication type:

Article

Distinct CG and CNG DNA methyltransferases in Pisum sativum.

Published in:

Plant Journal, 1995, v. 7, n. 3, p. 471, doi. 10.1046/j.1365-313X.1995.7030471.x

By:

Pradhan, Sriharsa;
Adams, Roger L.P.

Publication type:

Article

Distinct structural and functional heterochromatin partitioning of lamin B1 and lamin B2 revealed using genome-wide nicking enzyme epitope targeted DNA sequencing.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 2, p. 1, doi. 10.1093/nar/gkae1317

By:

Sen, Sagnik;
Estève, Pierre-Olivier;
Raman, Karthikeyan;
Beaulieu, Julie;
Chin, Hang Gyeong;
Feehery, George R;
Vishnu, Udayakumar S;
Xu, Shuang-yong;
Samuelson, James C;
Pradhan, Sriharsa

Publication type:

Article

Protect-seq: genome-wide profiling of nuclease inaccessible domains reveals physical properties of chromatin.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 3, p. e16, doi. 10.1093/nar/gkz1150

By:

Spracklin, George;
Pradhan, Sriharsa

Publication type:

Article

Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning.

Published in:

Nature, 2008, v. 452, n. 7184, p. 215, doi. 10.1038/nature06745

By:

Cokus, Shawn J.;
Feng, Suhua;
Zhang, Xiaoyu;
Chen, Zugen;
Merriman, Barry;
Haudenschild, Christian D.;
Pradhan, Sriharsa;
Nelson, Stanley F.;
Pellegrini, Matteo;
Jacobsen, Steven E.

Publication type:

Article

Isolation, characterization and baculovirus‐mediated expression of the cDNA encoding cytosine DNA methyltransferase from Pisum sativum.

Published in:

Nucleic Acids Research, 1998, v. 26, n. 5, p. 1214, doi. 10.1093/nar/26.5.1214

By:

Pradhan, Sriharsa;
Cummings, Michele;
Roberts, Richard J.;
Adams, Roger L. P.

Publication type:

Article

Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase.

Published in:

Nucleic Acids Research, 1997, v. 25, n. 22, p. 4666, doi. 10.1093/nar/25.22.4666

By:

Pradhan, Sriharsa;
Talbot, Dale;
Mi Sha;
Benner, Jack;
Hornstra, Linda;
En Li;
Jaenisch, Rudolf;
Roberts, Richard J.

Publication type:

Article

5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells.

Published in:

Genome Biology, 2011, v. 12, n. 6, p. 1, doi. 10.1186/gb-2011-12-6-r54

By:

Stroud, Hume;
Suhua Feng;
Kinney, Shannon Morey;
Pradhan, Sriharsa;
Jacobsen, Steven E.

Publication type:

Article

NicE-seq: high resolution open chromatin profiling.

Published in:

Genome Biology, 2017, v. 18, p. 1, doi. 10.1186/s13059-017-1247-6

By:

Ponnaluri, V. K. Chaithanya;
Guoqiang Zhang;
Estève, Pierre-Olivier;
Spracklin, George;
Sian, Stephanie;
Shuang-yong Xu;
Benoukraf, Touati;
Pradhan, Sriharsa

Publication type:

Article

Evaluation of UDP-GlcN Derivatives for Selective Labeling of 5-(Hydroxymethyl)cytosine.

Published in:

ChemBioChem, 2013, v. 14, n. 16, p. 2144, doi. 10.1002/cbic.201300294

By:

Dai, Nan;
Bitinaite, Jurate;
Chin, Hang‐Gyeong;
Pradhan, Sriharsa;
Corrêa, Ivan R.

Publication type:

Article

DNMT1-interacting RNAs block gene-specific DNA methylation.

Published in:

Nature, 2013, v. 503, n. 7476, p. 371, doi. 10.1038/nature12598

By:

Di Ruscio, Annalisa;
Ebralidze, Alexander K.;
Benoukraf, Touati;
Amabile, Giovanni;
Goff, Loyal A.;
Terragni, Jolyon;
Figueroa, Maria Eugenia;
De Figueiredo Pontes, Lorena Lobo;
Alberich-Jorda, Meritxell;
Zhang, Pu;
Wu, Mengchu;
D'Alò, Francesco;
Melnick, Ari;
Leone, Giuseppe;
Ebralidze, Konstantin K.;
Pradhan, Sriharsa;
Rinn, John L.;
Tenen, Daniel G.

Publication type:

Article

Emerging Approaches to Profile Accessible Chromatin from Formalin-Fixed Paraffin-Embedded Sections.

Published in:

Epigenomes, 2024, v. 8, n. 2, p. 20, doi. 10.3390/epigenomes8020020

By:

Sunitha Kumary, Vishnu Udayakumaran Nair;
Venters, Bryan J.;
Raman, Karthikeyan;
Sen, Sagnik;
Estève, Pierre-Olivier;
Cowles, Martis W.;
Keogh, Michael-Christopher;
Pradhan, Sriharsa

Publication type:

Article

Epigenetics of Genes Preferentially Expressed in Dissimilar Cell Populations: Myoblasts and Cerebellum.

Published in:

Epigenomes, 2024, v. 8, n. 1, p. 4, doi. 10.3390/epigenomes8010004

By:

Ehrlich, Melanie;
Ehrlich, Kenneth C.;
Lacey, Michelle;
Baribault, Carl;
Sen, Sagnik;
Estève, Pierre-Olivier;
Pradhan, Sriharsa

Publication type:

Article

Promoter-Adjacent DNA Hypermethylation Can Downmodulate Gene Expression: TBX15 in the Muscle Lineage.

Published in:

Epigenomes, 2022, v. 6, n. 4, p. 43, doi. 10.3390/epigenomes6040043

By:

Ehrlich, Kenneth C.;
Lacey, Michelle;
Baribault, Carl;
Sen, Sagnik;
Esteve, Pierre Olivier;
Pradhan, Sriharsa;
Ehrlich, Melanie

Publication type:

Article

A novel requirement for DROSHA in maintenance of mammalian CG methylation.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 16, p. 9398, doi. 10.1093/nar/gkx695

By:

Stathopoulou, Athanasia;
Chhetri, Jyoti B.;
Ambrose, John C.;
Estève, Pierre-Olivier;
Lexiang Ji;
Erdjument-Bromage, Hediye;
Guoqiang Zhang;
Neubert, Thomas A.;
Pradhan, Sriharsa;
Herrero, Javier;
Schmitz, Robert J.;
Ooi, Steen K. T.

Publication type:

Article

Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 4, p. 1642, doi. 10.1093/nar/gkv1162

By:

Est&áve, Pierre-Olivier;
Guoqiang Zhang;
Ponnaluri, V. K. Chaithanya;
Deepti, Kanneganti;
Hang Gyeong Chin;
Dai, Nan;
Sagum, Cari;
Black, Karynne;
Corrêa, Jr, Ivan R.;
Bedford, Mark T.;
Xiaodong Cheng;
Pradhan, Sriharsa

Publication type:

Article

Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 12, p. 6112, doi. 10.1093/nar/gkv518

By:

Guoqiang Zhang;
Estève, Pierre-Olivier;
Hang Gyeong Chin;
Terragni, Jolyon;
Nan Dai;
Correa Jr., Ivan R.;
Pradhan, Sriharsa

Publication type:

Article

Comparative characterization of the PvuRts1I family of restriction enzymes and their application in mapping genomic 5-hydroxymethylcytosine.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 21, p. 9294, doi. 10.1093/nar/gkr607

By:

Wang, Hua;
Guan, Shengxi;
Quimby, Aine;
Cohen-Karni, Devora;
Pradhan, Sriharsa;
Wilson, Geoffrey;
Roberts, Richard J.;
Zhu, Zhenyu;
Zheng, Yu

Publication type:

Article

A unique family of Mrr-like modification-dependent restriction endonucleases.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 16, p. 5527, doi. 10.1093/nar/gkq327

By:

Zheng, Yu;
Cohen-Karni, Devora;
Xu, Derrick;
Chin, Hang Gyeong;
Wilson, Geoffrey;
Pradhan, Sriharsa;
Roberts, Richard J.

Publication type:

Article

UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 2, p. 493, doi. 10.1093/nar/gkn961

By:

Kim, Jong Kyong;
Estève, Pierre-Olivier;
Jacobsen, Steven E.;
Pradhan, Sriharsa

Publication type:

Article

Automethylation of G9a and its implication in wider substrate specificity and HP1 binding.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 21, p. 7313, doi. 10.1093/nar/gkm726

By:

Chin, Hang Gyeong;
Estève, Pierre-Olivier;
Pradhan, Mihika;
Benner, Jack;
Patnaik, Debasis;
Carey, Michael F.;
Pradhan, Sriharsa

Publication type:

Article

Functional analysis of the N- and C-terminus of mammalian G9a histone H3 methyltransferase.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 10, p. 3211, doi. 10.1093/nar/gki635

By:

Estève, Pierre-Olivier;
Patnaik, Debasis;
Chin, Hang Gyeong;
Benner, Jack;
Teitell, Michael A.;
Pradhan, Sriharsa

Publication type:

Article

High-efficiency generation of induced pluripotent mesenchymal stem cells from human dermal fibroblasts using recombinant proteins.

Published in:

Stem Cell Research & Therapy, 2016, v. 7, p. 1, doi. 10.1186/s13287-016-0358-4

By:

Fanfan Chen;
Guoqiang Zhang;
Ling Yu;
Yanye Feng;
Xianghui Li;
Zhijun Zhang;
Yongting Wang;
Dapeng Sun;
Pradhan, Sriharsa

Publication type:

Article

Universal NicE-seq for high-resolution accessible chromatin profiling for formaldehyde-fixed and FFPE tissues.

Published in:

Clinical Epigenetics, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13148-020-00921-6

By:

Chin, Hang Gyeong;
Sun, Zhiyi;
Vishnu, Udayakumar S.;
Hao, Pengying;
Cejas, Paloma;
Spracklin, George;
Estève, Pierre-Olivier;
Xu, Shuang-yong;
Long, Henry W.;
Pradhan, Sriharsa

Publication type:

Article

Developmentally linked human DNA hypermethylation is associated with down-modulation, repression, and upregulation of transcription.

Published in:

Epigenetics, 2018, v. 13, n. 3, p. 275, doi. 10.1080/15592294.2018.1445900

By:

Baribault, Carl;
Ehrlich, Kenneth C.;
Ponnaluri, V. K. Chaithanya;
Pradhan, Sriharsa;
Lacey, Michelle;
Ehrlich, Melanie

Publication type:

Article

Association of 5-hydroxymethylation and 5-methylation of DNA cytosine with tissue-specific gene expression.

Published in:

Epigenetics, 2017, v. 12, n. 2, p. 123, doi. 10.1080/15592294.2016.1265713

By:

Ponnaluri, V. K. Chaithanya;
Ehrlich, Kenneth C.;
Zhang, Guoqiang;
Lacey, Michelle;
Johnston, Douglas;
Pradhan, Sriharsa;
Ehrlich, Melanie

Publication type:

Article

Notch signaling genes.

Published in:

Epigenetics, 2014, v. 9, n. 6, p. 842, doi. 10.4161/epi.28597

By:

Terragni, Jolyon;
Guoqiang Zhang;
Zhiyi Sun;
Pradhan, Sriharsa;
Lingyun Song;
Crawford, Gregory E.;
Lacey, Michelle;
Ehrlich, Melanie

Publication type:

Article

MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress.

Published in:

Epigenetics, 2014, v. 9, n. 4, p. 546, doi. 10.4161/epi.27695

By:

Laget, Sophie;
Miotto, Benoit;
Hang Gyeong Chin;
Estève, Pierre-Olivier;
Roberts, Richard J.;
Pradhan, Sriharsa;
Defossez, Pierre-Antoine

Publication type:

Article

Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.

Published in:

EMBO Journal, 2011, v. 30, n. 9, p. 1874, doi. 10.1038/emboj.2011.130

By:

Lindroth, Anders M;
Shultis, David;
Jasencakova, Zuzana;
Fuchs, Jörg;
Johnson, Lianna;
Schubert, Daniel;
Patnaik, Debasis;
Pradhan, Sriharsa;
Goodrich, Justin;
Schubert, Ingo;
Jenuwein, Thomas;
Khorasanizadeh, Sepideh;
Jacobsen, Steven E

Publication type:

Article

Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.

Published in:

EMBO Journal, 2004, v. 23, n. 21, p. 4286, doi. 10.1038/sj.emboj.7600430

By:

Lindroth, Anders M.;
Shultis, David;
Jasencakova, Zuzana;
Fuchs, Jörg;
Johnson, Lianna;
Schubert, Daniel;
Patnaik, Debasis;
Pradhan, Sriharsa;
Goodrich, Justin;
Schubert, Ingo;
Jenuweun, Thomas;
Khorasanizadeh, Sepideh;
Jacobsen, Steven E.

Publication type:

Article