Works matching AU Powers, Alvin C.

Results: 110

Observations on the Discovery of Glucagon-Like Peptide-1 Action.

Published in:

2025

By:

Philippe, Jacques;
Powers, Alvin C.

Publication type:

Opinion

Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes.

Published in:

Journal of the Endocrine Society, 2021, v. 5, n. 12, p. 1, doi. 10.1210/jendso/bvab162

By:

Haliyur, Rachana;
Walker, John T;
Sanyoura, May;
Reihsmann, Conrad V;
Shrestha, Shristi;
Aramandla, Radhika;
Poffenberger, Greg;
Ramirez, Andrea H;
Redick, Sambra D;
Babon, Jenny Aurielle B;
Prasad, Nripesh;
Hegele, Robert A;
Kent, Sally C;
Harlan, David M;
Bottino, Rita;
Philipson, Louis H;
Brissova, Marcela;
Powers, Alvin C

Publication type:

Article

Debates in Pancreatic Beta Cell Biology: Proliferation Versus Progenitor Differentiation and Transdifferentiation in Restoring β Cell Mass.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.722250

By:

Spears, Erick;
Serafimidis, Ioannis;
Powers, Alvin C.;
Gavalas, Anthony

Publication type:

Article

Human B Cells Secreting Immunoglobulin G to Glutamic Acid Decarboxylase-65 from a Nondiabetic Patient with Multiple Autoantibodies and Graves’ Disease: A Comparison with Those Present in Type 1 Diabetes.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 8, p. 2664, doi. 10.1210/jc.82.8.2664

By:

TREMBLE, JENNIFER;
MORGENTHALER, NILS G.;
VLUG, ARJEN;
POWERS, ALVIN C.;
CHRISTIE, MICHAEL R.;
SCHERBAUM, WERNER A.;
BANGA, J. PAUL

Publication type:

Article

Deep learning-based pancreas volume assessment in individuals with type 1 diabetes.

Published in:

BMC Medical Imaging, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12880-021-00729-7

By:

Roger, Raphael;
Hilmes, Melissa A.;
Williams, Jonathan M.;
Moore, Daniel J.;
Powers, Alvin C.;
Craddock, R. Cameron;
Virostko, John

Publication type:

Article

Decreased pancreatic acinar cell number in type 1 diabetes.

Published in:

Diabetologia, 2020, v. 63, n. 7, p. 1418, doi. 10.1007/s00125-020-05155-y

By:

Wright, Jordan J.;
Saunders, Diane C.;
Dai, Chunhua;
Poffenberger, Greg;
Cairns, Brynn;
Serreze, David V.;
Harlan, David M.;
Bottino, Rita;
Brissova, Marcela;
Powers, Alvin C.

Publication type:

Article

Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue.

Published in:

Diabetologia, 2019, v. 62, n. 6, p. 1036, doi. 10.1007/s00125-019-4855-8

By:

Prentice, Boone M.;
Hart, Nathaniel J.;
Phillips, Neil;
Haliyur, Rachana;
Judd, Audra;
Armandala, Radhika;
Spraggins, Jeffrey M.;
Lowe, Cindy L.;
Boyd, Kelli L.;
Stein, Roland W.;
Wright, Christopher V.;
Norris, Jeremy L.;
Powers, Alvin C.;
Brissova, Marcela;
Caprioli, Richard M.

Publication type:

Article

Use of human islets to understand islet biology and diabetes: progress, challenges and suggestions.

Published in:

Diabetologia, 2019, v. 62, n. 2, p. 212, doi. 10.1007/s00125-018-4772-2

By:

Hart, Nathaniel J.;
Powers, Alvin C.

Publication type:

Article

A Feasible Approach to Evaluate the Relative Reactivity of NHS-Ester Activated Group with Primary Amine-Derivatized DNA Analogue and Non-Derivatized Impurity.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2015, v. 34, n. 2, p. 69, doi. 10.1080/15257770.2014.958236

By:

Dou, Shuping;
Virostko, John;
Greiner, Dale L.;
Powers, Alvin C.;
Liu, Guozheng

Publication type:

Article

Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00172

By:

Shuping Dou;
Virostko, John;
Rusckowski, Mary;
Greiner, Dale L.;
Powers, Alvin C.;
Guozheng Liu;
Mizanur, Rahman M.;
Miaozong Wu

Publication type:

Article

CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1415102

By:

Xiangni Wu;
Pin-I Chen;
Whitener, Robert L.;
MacDougall, Matthew S.;
Coykendall, Vy M. N.;
Hao Yan;
Yong Bin Kim;
Harper, William;
Pathak, Shiva;
Iliopoulou, Bettina P.;
Hestor, Allison;
Saunders, Diane C.;
Spears, Erick;
Sévigny, Jean;
Maahs, David M.;
Basina, Marina;
Sharp, Seth A.;
Gloyn, Anna L.;
Powers, Alvin C.;
Kim, Seung K.

Publication type:

Article

Non-Invasive Bioluminescence Imaging of β-Cell Function in Obese-Hyperglycemic [ob/ob] Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106693

By:

Patel, Manishkumar;
Gleason, Alexa;
O'Malley, Stacey;
Connolly, Brett;
Suresch, Donna;
Virostko, John;
Phillips, Neil;
Lin, Shu-An;
Chen, Tsing-Bau;
Klimas, Michael;
Hargreaves, Richard J.;
Sur, Cyrille;
Williams Jr, David L.;
Powers, Alvin C.;
Bednar, Bohumil

Publication type:

Article

Bioluminescence Imaging Reveals Dynamics of Beta Cell Loss in the Non-Obese Diabetic (NOD) Mouse Model.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057784

By:

Virostko, John;
Radhika, Armandla;
Poffenberger, Greg;
Dula, Adrienne N.;
Moore, Daniel J.;
Powers, Alvin C.

Publication type:

Article

Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033529

By:

Reinert, Rachel B.;
Kantz, Jeannelle;
Misfeldt, Amanda Ackermann;
Poffenberger, Greg;
Gannon, Maureen;
Brissova, Marcela;
Powers, Alvin C.

Publication type:

Article

Determinants of glucose tolerance in inbred mouse strains.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A829, doi. 10.1096/fasebj.21.6.a829-c

By:

Berglund, Eric;
Li, Candice Y.;
Ayala, Julio E.;
Powers, Alvin C.;
Wasserman, David H.

Publication type:

Article

Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets.

Published in:

2004

By:

Brissova, Marcela;
Fowler, Michael;
Wiebe, Peter;
Shostak, Alena;
Shiota, Masakazu;
Radhika, Aramandla;
Lin, P. Charles;
Gannon, Maureen;
Powers, Alvin C.

Publication type:

journal article

Two distinct glutamic acid decarboxylase auto-antibody specificities in IDDM target different epitopes.

Published in:

1995

By:

Daw, Kendra;
Powers, Alvin C.;
Daw, K;
Powers, A C

Publication type:

journal article

Identification of glutamic acid decarboxylase autoantibody heterogeneity and epitope regions in type I diabetes.

Published in:

1994

By:

Ujihara, Noriko;
Daw, Kendra;
Gianani, Roberto;
Boel, Esper;
Liping Yu;
Powers, Alvin C.;
Ujihara, N;
Daw, K;
Gianani, R;
Boel, E;
Yu, L;
Powers, A C

Publication type:

journal article

Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor.

Published in:

1990

By:

Powers, Alvin C.;
Efrat, Shimon;
Mojsov, Svetlana;
Spector, David;
Habener, Joel F.;
Hanahan, Douglas;
Powers, A C;
Efrat, S;
Mojsov, S;
Spector, D;
Habener, J F;
Hanahan, D

Publication type:

journal article

Expression of peptide hormone genes in human islet cell tumors.

Published in:

1988

By:

Philippe, Jacques;
Powers, Alvin C.;
Mojsov, Svetlana;
Drucker, Daniel J.;
Comi, Richard;
Habener, Joel F.;
Philippe, J;
Powers, A C;
Mojsov, S;
Drucker, D J;
Comi, R;
Habener, J F

Publication type:

journal article

Sodium butyrate increases glucagon and insulin gene expression by recruiting immunocytochemically negative cells to produce hormone.

Published in:

1988

By:

Powers, Alvin C.;
Philippe, Jacques;
Hermann, Heather;
Habener, Joel F.;
Powers, A C;
Philippe, J;
Hermann, H;
Habener, J F

Publication type:

journal article

Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration.

Published in:

NPJ Regenerative Medicine, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41536-021-00129-z

By:

Saunders, Diane C.;
Aamodt, Kristie I.;
Richardson, Tiffany M.;
Hopkirk, Alexander J.;
Aramandla, Radhika;
Poffenberger, Greg;
Jenkins, Regina;
Flaherty, David K.;
Prasad, Nripesh;
Levy, Shawn E.;
Powers, Alvin C.;
Brissova, Marcela

Publication type:

Article

Hyperaminoacidemia induces pancreatic α cell proliferation via synergism between the mTORC1 and CaSR-Gq signaling pathways.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-35705-4

By:

Gong, Yulong;
Yang, Bingyuan;
Zhang, Dingdong;
Zhang, Yue;
Tang, Zihan;
Yang, Liu;
Coate, Katie C.;
Yin, Linlin;
Covington, Brittney A.;
Patel, Ravi S.;
Siv, Walter A.;
Sellick, Katelyn;
Shou, Matthew;
Chang, Wenhan;
Danielle Dean, E.;
Powers, Alvin C.;
Chen, Wenbiao

Publication type:

Article

Dapagliflozin Does Not Directly Affect Human α or β Cells.

Published in:

Endocrinology, 2020, v. 161, n. 8, p. 1, doi. 10.1210/endocr/bqaa080

By:

Dai, Chunhua;
Walker, John T;
Shostak, Alena;
Bouchi, Yasir;
Poffenberger, Greg;
Hart, Nathaniel J;
Jacobson, David A;
Calcutt, M Wade;
Bottino, Rita;
Greiner, Dale L;
Shultz, Leonard D;
McGuinness, Owen P;
Dean, E Danielle;
Powers, Alvin C

Publication type:

Article

Phospholipid and glutamic acid decarboxylase autoantibodies in diabetic neuropathy.

Published in:

1995

By:

Vinik, Aaron I.;
Leichter, Steven B.;
Pittenger, Gary L.;
Stansberry, Kevin B.;
Holland, Marie T.;
Powers, Alvin C.;
Suwanwalaikorn, Sompongse;
Vinik, A I;
Leichter, S B;
Pittenger, G L;
Stansberry, K B;
Holland, M T;
Powers, A C;
Suwanwalaikorn, S

Publication type:

journal article

Inactivation of specific β cell transcription factors in type 2 diabetes.

Published in:

2013

By:

Guo, Shuangli;
Dai, Chunhua;
Guo, Min;
Taylor, Brandon;
Harmon, Jamie S;
Sander, Maike;
Robertson, R Paul;
Powers, Alvin C;
Stein, Roland

Publication type:

journal article

Inactivation of specific ß cell transcription factors in type 2 diabetes.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 8, p. 3305, doi. 10.1172/JCI65390

By:

Guo, Shuangli;
Dai, Chunhua;
Guo, Min;
Taylor, Brandon;
Harmon, Jamie S.;
Sander, Maike;
Robertson, R. Paul;
Powers, Alvin C.;
Stein, Roland

Publication type:

Article

Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets.

Published in:

2008

By:

Nyman, R.;
Wells, K. Sam;
Head, W. Steve;
McCaughey, Michael;
Ford, Eric;
Brissova, Marcela;
Piston, David W.;
Powers, Alvin C.;
Nyman, Lara R

Publication type:

journal article

The obesity epidemic and rising diabetes incidence in a low-income racially diverse southern US cohort.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190993

By:

Conway, Baqiyyah N.;
Han, Xijing;
Munro, Heather M.;
Gross, Amy L.;
Shu, Xiao-Ou;
Hargreaves, Margaret K.;
Zheng, Wei;
Powers, Alvin C.;
Blot, William J.

Publication type:

Article

The Human Islet: Mini-Organ With Mega-Impact.

Published in:

Endocrine Reviews, 2021, v. 42, n. 5, p. 605, doi. 10.1210/endrev/bnab010

By:

Walker, John T;
Saunders, Diane C;
Brissova, Marcela;
Powers, Alvin C

Publication type:

Article

Humanized mice for the study of type 1 and type 2 diabetes.

Published in:

Annals of the New York Academy of Sciences, 2011, v. 1245, n. 1, p. 55, doi. 10.1111/j.1749-6632.2011.06318.x

By:

Greiner, Dale L.;
Brehm, Michael A.;
Hosur, Vishnu;
Harlan, David M.;
Powers, Alvin C.;
Shultz, Leonard D.

Publication type:

Article

Longitudinal MRI Shows Progressive Decline in Pancreas Size and Altered Pancreas Shape in Type 1 Diabetes.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 10, p. 2699, doi. 10.1210/clinem/dgad150

By:

Wright, Jordan J.;
Dulaney, Aidan;
Williams, Jonathan M.;
Hilmes, Melissa A.;
Liping Du;
Hakmook Kang;
Powers, Alvin C.;
Moore, Daniel J.;
Virostko, John

Publication type:

Article

Gene-Based Neurotransmitter Modulation in Cerebellar Granule Neurons.

Published in:

Journal of Neurochemistry, 1997, v. 68, n. 1, p. 204, doi. 10.1046/j.1471-4159.1997.68010204.x

By:

Fritz, Jeffery D.;
Utz, Andrea L.;
Hale, Nannette M.;
Wu, Lan;
Powers, Alvin C.;
Verdoorn, Todd A.;
Robertson, David

Publication type:

Article

Type 1 diabetes mellitus: much progress, many opportunities.

Published in:

2021

By:

Powers, Alvin C.

Publication type:

journal article

Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.

Published in:

2019

By:

Haliyur, Rachana;
Xin Tong;
May Sanyoura;
Shrestha, Shristi;
Lindner, Jill;
Saunders, Diane C.;
Aramandla, Radhika;
Poffenberger, Greg;
Redick, Sambra D.;
Bottino, Rita;
Prasad, Nripesh;
Levy, Shawn E.;
Blind, Raymond D.;
Harlan, David M.;
Philipson, Louis H.;
Stein, Roland W.;
Brissova, Marcela;
Powers, Alvin C.;
Tong, Xin;
Sanyoura, May

Publication type:

journal article

Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.

Published in:

2017

By:

Cummings, Kelsey;
Bozadjieva, Nadejda;
Bernal-Mizrachi, Ernesto;
Blandino-Rosano, Manuel;
Chase, Jennifer;
Gimeno, Jennifer;
Xiao-Qing Dai;
MacDonald, Patrick E.;
Dean, Danielle;
Powers, Alvin C.;
Gittes, George K.;
Rüegg, Markus A.;
Hall, Michael N.;
Dai, Xiao-Qing

Publication type:

journal article

Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.

Published in:

2017

By:

Dai, Chunhua;
Yan Hang;
Shostak, Alena;
Poffenberger, Greg;
Hart, Nathaniel;
Prasad, Nripesh;
Phillips, Neil;
Levy, Shawn E.;
Greiner, Dale L.;
Shultz, Leonard D.;
Bottino, Rita;
Kim, Seung K.;
Powers, Alvin C.;
Hang, Yan

Publication type:

journal article

Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.

Published in:

Journal of Clinical Investigation, 2016, v. 126, n. 5, p. 1857, doi. 10.1172/JCI83657

By:

Chunhua Dai;
Kayton, Nora S.;
Shostak, Alena;
Poffenberger, Greg;
Cyphert, Holly A.;
Aramandla, Radhika;
Thompson, Courtney;
Papagiannis, Ioannis G.;
Emfinger, Christopher;
Masakazu Shiota;
Stafford, John M.;
Greiner, Dale L.;
Herrera, Pedro L.;
Shultz, Leonard D.;
Stein, Roland;
Powers, Alvin C.

Publication type:

Article

Coupling of glucose transport and phosphorylation in Xenopus oocytes and cultured cells: Determination of the rate-limiting step.

Published in:

Journal of Cellular Physiology, 1993, v. 157, n. 3, p. 509, doi. 10.1002/jcp.1041570310

By:

Whitesell, Richard R.;
Aboumrad, Mireille K.;
Powers, Alvin C.;
Regen, David M.;
Le, Chinh;
Beechem, Joseph M.;
May, James M.;
Abumrad, Nada A.

Publication type:

Article

Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter‐firefly luciferase transgene.

Published in:

Genesis: The Journal of Genetics & Development, 2005, v. 43, n. 2, p. 80, doi. 10.1002/gene.20157

By:

Soo‐Young Park;
Xiaoyu Wang;
Zhongyi Chen;
Alvin C. Powers;
Mark A. Magnuson;
W. Steven Head;
David W. Piston;
Graeme I. Bell

Publication type:

Article

Affordable Care Act Implementation: Challenges and Opportunities to Impact Patients With Diabetes.

Published in:

2016

By:

Powers, Alvin C;
Wexler, Jason A;
Lash, Robert W;
Dyer, Meredith C;
Becker, Mila N;
Vigersky, Robert A

Publication type:

journal article

β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.

Published in:

2014

By:

Halban, Philippe A;
Polonsky, Kenneth S;
Bowden, Donald W;
Hawkins, Meredith A;
Ling, Charlotte;
Mather, Kieren J;
Powers, Alvin C;
Rhodes, Christopher J;
Sussel, Lori;
Weir, Gordon C

Publication type:

journal article

Comparative analysis of epitope recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different autoimmune disorders.

Published in:

Clinical & Experimental Immunology, 1999, v. 118, n. 3, p. 349, doi. 10.1046/j.1365-2249.1999.01030.x

By:

Powers;
Bavik;
Tremble;
Daw;
Scherbaum;
Banga;
C. Powers, Alvin

Publication type:

Article

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00561-0

By:

Cogger, Kathryn F.;
Sinha, Ankit;
Sarangi, Farida;
McGaugh, Emily C.;
Saunders, Diane;
Dorrell, Craig;
Mejia-Guerrero, Salvador;
Aghazadeh, Yasaman;
Rourke, Jillian L.;
Screaton, Robert A.;
Grompe, Markus;
Streeter, Philip R.;
Powers, Alvin C.;
Brissova, Marcela;
Kislinger, Thomas;
Nostro, M. Cristina

Publication type:

Article

Use of the Electronic Medical Record to Assess Pancreas Size in Type 1 Diabetes.

Published in:

PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0158825

By:

Virostko, John;
Hilmes, Melissa;
Eitel, Kelsey;
Moore, Daniel J.;
Powers, Alvin C.

Publication type:

Article

Longitudinal Assessment of Pancreas Volume by MRI Predicts Progression to Stage 3 Type 1 Diabetes.

Published in:

Diabetes Care, 2024, v. 47, n. 3, p. 393, doi. 10.2337/dc23-1681

By:

Virostko, John;
Wright, Jordan J.;
Williams, Jonathan M.;
Hilmes, Melissa A.;
Triolo, Taylor M.;
Broncucia, Hali;
Du, Liping;
Kang, Hakmook;
Nallaparaju, Shreya;
Valencia, Leah Galvez;
Reyes, Demetra;
Hammel, Brenna;
Russell, William E.;
Philipson, Louis H.;
Waibel, Michaela;
Kay, Thomas W.H.;
Thomas, Helen E.;
Greeley, Siri Atma W.;
Steck, Andrea K.;
Powers, Alvin C.

Publication type:

Article

Insulin Deficiency From Insulin Gene Mutation Leads to Smaller Pancreas.

Published in:

Diabetes Care, 2023, v. 46, n. 4, p. 773, doi. 10.2337/dc22-2082

By:

Wright, Jordan J.;
Williams, Jonathan M.;
Letourneau-Freiberg, Lisa R.;
Kandasamy, Balamurugan;
Reyes, Demetra;
Kanegusuku, Anastasia Gant;
Philipson, Louis;
Greeley, Siri Atma W.;
Hilmes, Melissa A.;
Powers, Alvin C.;
Virostko, John;
Moore, Daniel J.

Publication type:

Article

Images From the Exeter Archival Diabetes Biobank Now Accessible via Pancreatlas.

Published in:

Diabetes Care, 2022, v. 45, n. 12, p. e174, doi. 10.2337/dc22-1613

By:

Morgan, Noel G.;
Richardson, Sarah J.;
Powers, Alvin C.;
Saunders, Diane C.;
Brissova, Marcela

Publication type:

Article

Pancreas Volume Declines During the First Year After Diagnosis of Type 1 Diabetes and Exhibits Altered Diffusion at Disease Onset.

Published in:

2019

By:

Virostko, John;
Williams, Jon;
Hilmes, Melissa;
Bowman, Chris;
Wright, Jordan J.;
Liping Du;
Hakmook Kang;
Russell, William E.;
Powers, Alvin C.;
Moore, Daniel J.;
Du, Liping;
Kang, Hakmook

Publication type:

journal article

Increased Reporting of Immune Checkpoint Inhibitor-Associated Diabetes.

Published in:

2018

By:

Wright, Jordan J.;
Salem, Joe-Elie;
Johnson, Douglas B.;
Lebrun-Vignes, Bénédicte;
Stamatouli, Angeliki;
Thomas, James W.;
Herold, Kevan C.;
Moslehi, Javid;
Powers, Alvin C.

Publication type:

Letter