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Xanomeline displays concomitant orthosteric and allosteric binding modes at the M<sub>4</sub> mAChR.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41199-5
By:
- Burger, Wessel A. C.;
- Pham, Vi;
- Vuckovic, Ziva;
- Powers, Alexander S.;
- Mobbs, Jesse I.;
- Laloudakis, Yianni;
- Glukhova, Alisa;
- Wootten, Denise;
- Tobin, Andrew B.;
- Sexton, Patrick M.;
- Paul, Steven M.;
- Felder, Christian C.;
- Danev, Radostin;
- Dror, Ron O.;
- Christopoulos, Arthur;
- Valant, Celine;
- Thal, David M.
Publication type:
Article
Structural basis for activation of CB1 by an endocannabinoid analog.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37864-4
By:
- Krishna Kumar, Kaavya;
- Robertson, Michael J.;
- Thadhani, Elina;
- Wang, Haoqing;
- Suomivuori, Carl-Mikael;
- Powers, Alexander S.;
- Ji, Lipin;
- Nikas, Spyros P.;
- Dror, Ron O.;
- Inoue, Asuka;
- Makriyannis, Alexandros;
- Skiniotis, Georgios;
- Kobilka, Brian
Publication type:
Article
CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.90648
By:
- Mengyuan Xu;
- Neelands, Torben;
- Powers, Alexander S.;
- Yan Liu;
- Miller, Steven D.;
- Pintilie, Grigore D.;
- Bois, J. Du;
- Dror, Ron O.;
- Wah Chiu;
- Maduke, Merritt
Publication type:
Article