Works by Pouton, Colin W.

Results: 32

Colloidal characteristics and formulation of pure protein particulate vaccines.

Published in:

Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 10, p. 1386, doi. 10.1111/j.2042-7158.2012.01513.x

By:

White, Paul J.;
Hickey, Pascal;
Sze Tu, Linda;
Headey, Stephen J.;
Scanlon, Martin J.;
Boyd, Ben J.;
Pouton, Colin W.

Publication type:

Article

Human leukocyte antigen haplotype phasing by allele-specific enrichment with peptide nucleic acid probes.

Published in:

Molecular Genetics & Genomic Medicine, 2014, v. 2, n. 3, p. 245, doi. 10.1002/mgg3.65

By:

Murphy, Nicholas M.;
Pouton, Colin W.;
Irving, Helen R.

Publication type:

Article

A Microtubule-Facilitated Nuclear Import Pathway for Cancer Regulatory Proteins.

Published in:

Traffic, 2007, v. 8, n. 6, p. 673, doi. 10.1111/j.1600-0854.2007.00564.x

By:

Roth, Daniela Martino;
Moseley, Gregory W.;
Glover, Dominic;
Pouton, Colin W.;
Jans, David A.

Publication type:

Article

Beyond the Endosomal Bottleneck: Understanding the Efficiency of mRNA/LNP Delivery.

Published in:

Advanced Functional Materials, 2024, v. 34, n. 39, p. 1, doi. 10.1002/adfm.202404510

By:

Liu, Haiyin;
Chen, Moore Z.;
Payne, Thomas;
Porter, Christopher J.H.;
Pouton, Colin W.;
Johnston, Angus P.R.

Publication type:

Article

Heterogeneous population of dopaminergic neurons derived from mouse embryonic stem cells: preliminary phenotyping based on receptor expression and function.

Published in:

European Journal of Neuroscience, 2007, v. 25, n. 7, p. 1961, doi. 10.1111/j.1460-9568.2007.05489.x

By:

Raye, Warren S.;
Tochon‐Danguy, Nathalie;
Pouton, Colin W.;
Haynes, John M.

Publication type:

Article

The Synthesis and Biological Evaluation of Multifunctionalised Derivatives of Noscapine as Cytotoxic Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 399, doi. 10.1002/cmdc.201300395

By:

DeBono, Aaron J.;
Mistry, Sarah J.;
Xie, Jinhan;
Muthiah, Divya;
Phillips, Jackson;
Ventura, Sabatino;
Callaghan, Richard;
Pouton, Colin W.;
Capuano, Ben;
Scammells, Peter J.

Publication type:

Article

Synthesis and Biological Evaluation of N-Substituted Noscapine Analogues.

Published in:

ChemMedChem, 2012, v. 7, n. 12, p. 2122, doi. 10.1002/cmdc.201200365

By:

DeBono, Aaron J.;
Xie, Jin Han;
Ventura, Sabatino;
Pouton, Colin W.;
Capuano, Ben;
Scammells, Peter J.

Publication type:

Article

Synthesis and Biological Evaluation of Adenosines with Heterobicyclic and Polycyclic N6-Substituents as Adenosine A1 Receptor Agonists.

Published in:

ChemMedChem, 2012, v. 7, n. 7, p. 1191, doi. 10.1002/cmdc.201200208

By:

Gosling, Joshua I.;
Baker, Stephen P.;
Haynes, John M.;
Kassiou, Michael;
Pouton, Colin W.;
Warfe, Lyndon;
White, Paul J.;
Scammells, Peter J.

Publication type:

Article

Embryonic stem cells as a source of models for drug discovery.

Published in:

2007

By:

Pouton, Colin W.;
Haynes, John M.

Publication type:

review

Molecular modeling of lipid drug formulations.

Published in:

2012

By:

Birru, Woldeamanuel A.;
Warren, Dallas B.;
Porter, Christopher J. H.;
Pouton, Colin W.;
Chalmers, David K.

Publication type:

Abstract

Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 48, p. 9521, doi. 10.1523/JNEUROSCI.1160-19.2019

By:

de Luzy, Isabelle R.;
Niclis, Jonathan C.;
Gantner, Carlos W.;
Kauhausen, Jessica A.;
Hunt, Cameron P. J.;
Ermine, Charlotte;
Pouton, Colin W.;
Thompson, Lachlan H.;
Parish, Clare L.

Publication type:

Article

Molecular Dynamics Simulations and Experimental Results Provide Insight into Clinical Performance Differences between Sandimmune® and Neoral® Lipid-Based Formulations.

Published in:

Pharmaceutical Research, 2021, v. 38, n. 9, p. 1531, doi. 10.1007/s11095-021-03099-5

By:

Warren, Dallas B.;
Haque, Shadabul;
McInerney, Mitchell P.;
Corbett, Karen M.;
Kastrati, Endri;
Ford, Leigh;
Williams, Hywel D.;
Jannin, Vincent;
Benameur, Hassan;
Porter, Christopher J.H.;
Chalmers, David K.;
Pouton, Colin W.

Publication type:

Article

Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide.

Published in:

Pharmaceutical Research, 2021, v. 38, n. 6, p. 1125, doi. 10.1007/s11095-021-03063-3

By:

Li, Peng;
Ford, Leigh;
Haque, Shadabul;
McInerney, Mitchell P.;
Williams, Hywel D.;
Scammells, Peter J.;
Thompson, Philip E.;
Jannin, Vincent;
Porter, Christopher J. H.;
Benameur, Hassan;
Pouton, Colin W.

Publication type:

Article

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 3: Understanding Supersaturation Versus Precipitation Potential During the In Vitro Digestion of Type I, II, IIIA, IIIB and IV Lipid-Based Formulations.

Published in:

Pharmaceutical Research, 2013, v. 30, n. 12, p. 3059, doi. 10.1007/s11095-013-1038-z

By:

Williams, Hywel D.;
Sassene, Philip;
Kleberg, Karen;
Calderone, Marilyn;
Igonin, Annabel;
Jule, Eduardo;
Vertommen, Jan;
Blundell, Ross;
Benameur, Hassan;
Müllertz, Anette;
Pouton, Colin W.;
Porter, Christopher J. H.

Publication type:

Article

Glyceride Lipid Formulations: Molecular Dynamics Modeling of Phase Behavior During Dispersion and Molecular Interactions Between Drugs and Excipients.

Published in:

Pharmaceutical Research, 2013, v. 30, n. 12, p. 3238, doi. 10.1007/s11095-013-1206-1

By:

Warren, Dallas B.;
King, Dylan;
Benameur, Hassan;
Pouton, Colin W.;
Chalmers, David K.

Publication type:

Article

Lipid-Based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/Absorption Pathway.

Published in:

Pharmaceutical Research, 2013, v. 30, n. 12, p. 2976, doi. 10.1007/s11095-013-1126-0

By:

Williams, Hywel D.;
Trevaskis, Natalie L.;
Yeap, Yan Yan;
Anby, Mette U.;
Pouton, Colin W.;
Porter, Christopher J. H.

Publication type:

Article

Adenovirus Terminal Protein Contains a Bipartite Nuclear Localisation Signal Essential for Its Import into the Nucleus.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3310, doi. 10.3390/ijms22073310

By:

Al-Wassiti, Hareth A.;
Thomas, David R.;
Wagstaff, Kylie M.;
Fabb, Stewart A.;
Jans, David A.;
Johnston, Angus P.;
Pouton, Colin W.;
Naumann, Ulrike

Publication type:

Article

Investigations into the Binding Affinities of Different Human 5-HT4 Receptor Splice Variants.

Published in:

Pharmacology, 2010, v. 85, n. 4, p. 224, doi. 10.1159/000280418

By:

Irving, Helen R.;
Tochon-Danguy, Nathalie;
Chinkwo, Kenneth A.;
Li, Jian G.;
Grabbe, Carmen;
Shapiro, Marina;
Pouton, Colin W.;
Coupar, Ian M.

Publication type:

Article

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination.

Published in:

Nature Communications, 2016, v. 7, n. 3, p. 10634, doi. 10.1038/ncomms10634

By:

Le, Caroline P.;
Nowell, Cameron J.;
Kim-Fuchs, Corina;
Botteri, Edoardo;
Hiller, Jonathan G.;
Ismail, Hilmy;
Pimentel, Matthew A.;
Chai, Ming G.;
Karnezis, Tara;
Rotmensz, Nicole;
Renne, Giuseppe;
Gandini, Sara;
Pouton, Colin W.;
Ferrari, Davide;
Möller, Andreas;
Stacker, Steven A.;
Sloan, Erica K.

Publication type:

Article

Inhibition of β-catenin dependent WNT signalling upregulates the transcriptional repressor NR0B1 and downregulates markers of an A9 phenotype in human embryonic stem cell-derived dopaminergic neurons: Implications for Parkinson's disease.

Published in:

PLoS ONE, 2021, v. 16, n. 12, p. 1, doi. 10.1371/journal.pone.0261730

By:

Haynes, John M.;
Sibuea, Shanti M.;
Aguiar, Alita A.;
Li, Fangwei;
Ho, Joan K.;
Pouton, Colin W.

Publication type:

Article

Modulation of nucleocytoplasmic trafficking by retention in cytoplasm or nucleus.

Published in:

Journal of Cellular Biochemistry, 2009, v. 107, n. 6, p. 1160, doi. 10.1002/jcb.22218

By:

Roth, Daniela M.;
Harper, Ian;
Pouton, Colin W.;
Jans, David A.

Publication type:

Article

Haplotyping the human leukocyte antigen system from single chromosomes.

Published in:

Scientific Reports, 2016, p. 30381, doi. 10.1038/srep30381

By:

Murphy, Nicholas M.;
Burton, Matthew;
Powell, David R.;
Rossello, Fernando J.;
Cooper, Don;
Chopra, Abha;
Hsieh, Ming Je;
Sayer, David C.;
Gordon, Lavinia;
Pertile, Mark D;
Tait, Brian D.;
Irving, Helen R.;
Pouton, Colin W.

Publication type:

Article

DNA-Dependent Protein Kinase Is a Context Dependent Regulator of Lmx1a and Midbrain Specification.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0078759

By:

Hunt, Cameron P.;
Fabb, Stewart A.;
Pouton, Colin W.;
Haynes, John M.

Publication type:

Article

In Vitro Maturation of Dopaminergic Neurons Derived from Mouse Embryonic Stem Cells: Implications for Transplantation.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031999

By:

Watmuff, Bradley;
Pouton, Colin W.;
Haynes, John M.

Publication type:

Article

Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility.

Published in:

Journal of Drug Targeting, 2010, v. 18, n. 10, p. 704, doi. 10.3109/1061186X.2010.525652

By:

Warren, Dallas B.;
Benameur, Hassan;
Porter, Christopher J.H.;
Pouton, Colin W.

Publication type:

Article

Resolving subcellular pH with a quantitative fluorescent lifetime biosensor.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33348-z

By:

Rennick, Joshua J.;
Nowell, Cameron J.;
Pouton, Colin W.;
Johnston, Angus P. R.

Publication type:

Article

Temperature Replica Exchange Molecular Dynamics Simulations of Cyclic Peptide Conformation.

Published in:

Australian Journal of Chemistry, 2021, v. 74, n. 9, p. 684, doi. 10.1071/CH21120

By:

Corbett, Karen M.;
Pouton, Colin W.;
Chalmers, David K.

Publication type:

Article

Lmx1a Allows Context-Specific Isolation of Progenitors of GABAergic or Dopaminergic Neurons During Neural Differentiation of Embryonic Stem Cells.

Published in:

Stem Cells, 2012, v. 30, n. 7, p. 1349, doi. 10.1002/stem.1105

By:

Nefzger, Christian M.;
Su, Colin T.;
Fabb, Stewart A.;
Hartley, Brigham J.;
Beh, Siew J.;
Zeng, Wendy R.;
Haynes, John M.;
Pouton, Colin W.

Publication type:

Article

Directed Expression of Gata2, Mash1, and Foxa2 Synergize to Induce the Serotonergic Neuron Phenotype During In Vitro Differentiation of Embryonic Stem Cells.

Published in:

Stem Cells, 2011, v. 29, n. 6, p. 928, doi. 10.1002/stem.640

By:

NEFZGER, CHRISTIAN M.;
HAYNES, JOHN M.;
POUTON, COLIN W.

Publication type:

Article

A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives.

Published in:

Stem Cells, 2011, v. 29, n. 3, p. 462, doi. 10.1002/stem.587

By:

Goulburn, Adam L.;
Alden, Darym;
Davis, Richard P.;
Micallef, Suzanne J.;
Ng, Elizabeth S.;
Yu, Qing C.;
Lim, Sue Mei;
Soh, Chew-Li;
Elliott, David A.;
Hatzistavrou, Tanya;
Bourke, Justin;
Watmuff, Bradley;
Lang, Richard J.;
Haynes, John M.;
Pouton, Colin W.;
Giudice, Antonietta;
Trounson, Alan O.;
Anderson, Stewart A.;
Stanley, Edouard G.;
Elefanty, Andrew G.

Publication type:

Article

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.

Published in:

Stem Cells Translational Medicine, 2017, v. 6, n. 3, p. 937, doi. 10.5966/sctm.2016-0073

By:

Niclis, Jonathan C.;
Gantner, Carlos W.;
Alsanie, Walaa F.;
McDougall, Stuart J.;
Bye, Chris R.;
Elefanty, Andrew G.;
Stanley, Edouard G.;
Haynes, John M.;
Pouton, Colin W.;
Thompson, Lachlan H.;
Parish, Clare L.

Publication type:

Article

Unravelling cytosolic delivery of cell penetrating peptides with a quantitative endosomal escape assay.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23997-x

By:

Teo, Serena L. Y.;
Rennick, Joshua J.;
Yuen, Daniel;
Al-Wassiti, Hareth;
Johnston, Angus P. R.;
Pouton, Colin W.

Publication type:

Article

Works by Pouton, Colin W.

Colloidal characteristics and formulation of pure protein particulate vaccines.

Human leukocyte antigen haplotype phasing by allele-specific enrichment with peptide nucleic acid probes.

A Microtubule-Facilitated Nuclear Import Pathway for Cancer Regulatory Proteins.

Beyond the Endosomal Bottleneck: Understanding the Efficiency of mRNA/LNP Delivery.

Heterogeneous population of dopaminergic neurons derived from mouse embryonic stem cells: preliminary phenotyping based on receptor expression and function.

The Synthesis and Biological Evaluation of Multifunctionalised Derivatives of Noscapine as Cytotoxic Agents.

Synthesis and Biological Evaluation of N-Substituted Noscapine Analogues.

Synthesis and Biological Evaluation of Adenosines with Heterobicyclic and Polycyclic N<sup>6</sup>-Substituents as Adenosine A<sub>1</sub> Receptor Agonists.

Embryonic stem cells as a source of models for drug discovery.

Molecular modeling of lipid drug formulations.

Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease.

Molecular Dynamics Simulations and Experimental Results Provide Insight into Clinical Performance Differences between Sandimmune® and Neoral® Lipid-Based Formulations.

Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide.

Toward the Establishment of Standardized <i>In Vitro</i> Tests for Lipid-Based Formulations, Part 3: Understanding Supersaturation <i>Versus</i> Precipitation Potential During the <i>In Vitro</i> Digestion of Type I, II, IIIA, IIIB and IV Lipid-Based Formulations.

Glyceride Lipid Formulations: Molecular Dynamics Modeling of Phase Behavior During Dispersion and Molecular Interactions Between Drugs and Excipients.

Lipid-Based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/Absorption Pathway.

Adenovirus Terminal Protein Contains a Bipartite Nuclear Localisation Signal Essential for Its Import into the Nucleus.

Investigations into the Binding Affinities of Different Human 5-HT<sub>4</sub> Receptor Splice Variants.

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination.

Inhibition of β-catenin dependent WNT signalling upregulates the transcriptional repressor NR0B1 and downregulates markers of an A9 phenotype in human embryonic stem cell-derived dopaminergic neurons: Implications for Parkinson's disease.

Modulation of nucleocytoplasmic trafficking by retention in cytoplasm or nucleus.

Haplotyping the human leukocyte antigen system from single chromosomes.

DNA-Dependent Protein Kinase Is a Context Dependent Regulator of Lmx1a and Midbrain Specification.

In Vitro Maturation of Dopaminergic Neurons Derived from Mouse Embryonic Stem Cells: Implications for Transplantation.

Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility.

Resolving subcellular pH with a quantitative fluorescent lifetime biosensor.

Temperature Replica Exchange Molecular Dynamics Simulations of Cyclic Peptide Conformation.

Lmx1a Allows Context-Specific Isolation of Progenitors of GABAergic or Dopaminergic Neurons During Neural Differentiation of Embryonic Stem Cells.

Directed Expression of Gata2, Mash1, and Foxa2 Synergize to Induce the Serotonergic Neuron Phenotype During In Vitro Differentiation of Embryonic Stem Cells.

A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives.

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.

Unravelling cytosolic delivery of cell penetrating peptides with a quantitative endosomal escape assay.