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Neutrophil hyperactivation correlates with Alzheimer's disease progression.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Long-lasting correction of in vivo LTP and cognitive deficits of mice modelling Down syndrome with an α5-selective GABA<sub>A</sub> inverse agonist.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Lipid Dys-Homeostasis Contributes to APOE4-Associated AD Pathology.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 22, p. 3616, doi. 10.3390/cells11223616
- By:
- Publication type:
- Article
Alzheimer's Disease: Tau Pathology and Dysfunction of Endocytosis.
- Published in:
- Frontiers in Molecular Neuroscience, 2021, v. 13, p. N.PAG, doi. 10.3389/fnmol.2020.583755
- By:
- Publication type:
- Article
Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis.
- Published in:
- FASEB Journal, 2011, v. 25, n. 4, p. 1295, doi. 10.1096/fj.10-168633
- By:
- Publication type:
- Article
In vivo <sup>1</sup>H MRS study in microlitre voxels in the hippocampus of a mouse model of Down syndrome at 11.7 T.
- Published in:
- NMR in Biomedicine, 2014, v. 27, n. 10, p. 1143, doi. 10.1002/nbm.3155
- By:
- Publication type:
- Article
Cholesterol and ApoE in Alzheimer's disease.
- Published in:
- Oilseeds & Fats, Crops & Lipids (OCL), 2018, v. 25, n. 4, p. 1, doi. 10.1051/ocl/2018038
- By:
- Publication type:
- Article
Trisomy for Synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes.
- Published in:
- Human Molecular Genetics, 2012, v. 21, n. 14, p. 3156, doi. 10.1093/hmg/dds142
- By:
- Publication type:
- Article
Hypoxanthine-guanine phosphoribosyl transferase regulates early developmental programming of dopamine neurons: implications for Lesch-Nyhan disease pathogenesis.
- Published in:
- Human Molecular Genetics, 2009, v. 18, n. 13, p. 2317, doi. 10.1093/hmg/ddp164
- By:
- Publication type:
- Article
Distinct dynamic profiles of microglial activation are associated with progression of Alzheimer's disease.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development.
- Published in:
- BMC Genomics, 2009, v. 10, p. 1, doi. 10.1186/1471-2164-10-138
- By:
- Publication type:
- Article
Specific Mutations in the Cholesterol-Binding Site of APP Alter Its Processing and Favor the Production of Shorter, Less Toxic Aβ Peptides.
- Published in:
- Molecular Neurobiology, 2022, v. 59, n. 11, p. 7056, doi. 10.1007/s12035-022-03025-9
- By:
- Publication type:
- Article
BDNF and DYRK1A Are Variable and Inversely Correlated in Lymphoblastoid Cell Lines from Down Syndrome Patients.
- Published in:
- Molecular Neurobiology, 2012, v. 46, n. 2, p. 297, doi. 10.1007/s12035-012-8284-7
- By:
- Publication type:
- Article
Amyloid-β peptide signature associated with cerebral amyloid angiopathy in familial Alzheimer's disease with APPdup and Down syndrome.
- Published in:
- Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02756-4
- By:
- Publication type:
- Article
Picalm reduction exacerbates tau pathology in a murine tauopathy model.
- Published in:
- Acta Neuropathologica, 2020, v. 139, n. 4, p. 773, doi. 10.1007/s00401-020-02125-x
- By:
- Publication type:
- Article
Patterns and severity of vascular amyloid in Alzheimer’s disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer’s disease.
- Published in:
- Acta Neuropathologica, 2018, v. 136, n. 4, p. 569, doi. 10.1007/s00401-018-1866-3
- By:
- Publication type:
- Article
Inside Alzheimer brain with CLARITY: senile plaques, neurofibrillary tangles and axons in 3-D.
- Published in:
- 2014
- By:
- Publication type:
- Letter
Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brains.
- Published in:
- Acta Neuropathologica, 2013, v. 125, n. 6, p. 861, doi. 10.1007/s00401-013-1111-z
- By:
- Publication type:
- Article
Classification and basic pathology of Alzheimer disease.
- Published in:
- Acta Neuropathologica, 2009, v. 118, n. 1, p. 5, doi. 10.1007/s00401-009-0532-1
- By:
- Publication type:
- Article
Cholesterol in the senile plaque: often mentioned, never seen.
- Published in:
- Acta Neuropathologica, 2009, v. 117, n. 1, p. 31, doi. 10.1007/s00401-008-0448-1
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- Publication type:
- Article
Alzheimer disease models and human neuropathology: similarities and differences.
- Published in:
- Acta Neuropathologica, 2008, v. 115, n. 1, p. 5, doi. 10.1007/s00401-007-0312-8
- By:
- Publication type:
- Article
Ultrastructural and dynamic studies of the endosomal compartment in Down syndrome.
- Published in:
- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00956-z
- By:
- Publication type:
- Article
Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer's disease and not in other tauopathies.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0848-6
- By:
- Publication type:
- Article
Innovating Therapies for Down Syndrome: An International Virtual Conference of the T21 Research Society.
- Published in:
- Molecular Syndromology, 2023, v. 14, n. 2, p. 89, doi. 10.1159/000526021
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- Publication type:
- Article
Building the Future Therapies for Down Syndrome: The Third International Conference of the T21 Research Society.
- Published in:
- Molecular Syndromology, 2021, v. 12, n. 4, p. 202, doi. 10.1159/000514437
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- Publication type:
- Article
Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society.
- Published in:
- Molecular Syndromology, 2018, v. 9, n. 6, p. 279, doi. 10.1159/000494231
- By:
- Publication type:
- Article
Changing Paradigms in Down Syndrome: The First International Conference of the Trisomy 21 Research Society.
- Published in:
- Molecular Syndromology, 2016, v. 7, n. 5, p. 251, doi. 10.1159/000449049
- By:
- Publication type:
- Article
Converting disease maps into heavyweight ontologies: general methodology and application to Alzheimer's disease.
- Published in:
- Database: The Journal of Biological Databases & Curation, 2021, v. 2021, p. 1, doi. 10.1093/database/baab004
- By:
- Publication type:
- Article
Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer's disease early phenotypes.
- Published in:
- Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-60
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- Publication type:
- Article
Altered age-linked regulation of plasma DYRK1A in elderly cognitive complainers (INSIGHT-preAD study)with high brain amyloid load.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12046
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- Publication type:
- Article
Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse model of Down syndrome.
- Published in:
- eLife, 2020, p. 1, doi. 10.7554/eLife.58731
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- Publication type:
- Article
Increased plasma DYRK1A with aging may protect against neurodegenerative diseases.
- Published in:
- Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02419-0
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- Publication type:
- Article
Modifications of the endosomal compartment in fibroblasts from sporadic Alzheimer's disease patients are associated with cognitive impairment.
- Published in:
- Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02355-z
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- Publication type:
- Article
Demyelination Causes Adult CNS Progenitors to Revert to an Immature State and Express Immune Cues That Support Their Migration.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 1, p. 4, doi. 10.1523/JNEUROSCI.0849-14.2015
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- Publication type:
- Article
Sex differences in cortical microstructural changes in asymptomatic individuals at risk for Alzheimer's disease: Neuroimaging / imaging and genetics.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046105
- By:
- Publication type:
- Article
Cortical microstructural changes and amyloid beta burden in cognitively normal subjective memory complainers: Neuroimaging / Optimal neuroimaging measures for early detection.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046014
- By:
- Publication type:
- Article
Sensitivity and specificity of EEG biomarkers of AD at the preclinical stage: Biomarkers (non‐neuroimaging) / novel biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045832
- By:
- Publication type:
- Article
Aging and sex impact plasma NFL and t‐Tau trajectories in individuals at risk for Alzheimer's disease: Biomarkers (non‐neuroimaging) / plasma/serum/urine biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041792
- By:
- Publication type:
- Article
Association of plasma YKL‐40 with brain amyloidosis, memory performance, and sex in subjective memory complainers: Biomarkers (non‐neuroimaging) / plasma/serum/urine biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041753
- By:
- Publication type:
- Article
Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, n. 10, p. 1274, doi. 10.1016/j.jalz.2019.07.001
- By:
- Publication type:
- Article
P4‐021: PLASMA BETA‐SECRETASE 1 CONCENTRATIONS IMPACT PLASMA NFL CONCENTRATIONS IN COGNITIVELY NORMAL INDIVIDUALS AT RISK FOR AD: CROSS‐SECTIONAL AND LONGITUDINAL STUDIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1281, doi. 10.1016/j.jalz.2019.06.3680
- By:
- Publication type:
- Article
P3‐324: CONCURRENT EEG/FMRI NETWORK DYNAMICS ALTERATIONS IN COGNITIVELY INTACT INDIVIDUALS AT RISK FOR ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1062, doi. 10.1016/j.jalz.2019.06.3356
- By:
- Publication type:
- Article
P3‐235: PLASMA TAU IS ASSOCIATED WITH BASAL FOREBRAIN RATE OF ATROPHY IN OLDER ADULTS AT RISK OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1024, doi. 10.1016/j.jalz.2019.06.3265
- By:
- Publication type:
- Article
P3‐110: PRECLINICAL ALZHEIMER'S DISEASE: WHICH EEG BIOMARKERS FOR PRECISION MEDICINE?
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P972, doi. 10.1016/j.jalz.2019.06.3138
- By:
- Publication type:
- Article
O3‐02‐04: APOE AFFECTS THE NETWORK ARCHITECTURE OF THE RESTING BRAIN IN INDIVIDUALS AT RISK FOR AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P879, doi. 10.1016/j.jalz.2019.06.4633
- By:
- Publication type:
- Article
P2‐339: ASSOCIATION BETWEEN BRAIN NETWORK DYNAMICS AND PLASMA BIOMARKERS IN COGNITIVELY INTACT INDIVIDUALS AT RISK FOR ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P722, doi. 10.1016/j.jalz.2019.06.2746
- By:
- Publication type:
- Article
P2‐034: PLASMA BETA‐SECRETASE 1 CONCENTRATIONS PREDICT GLOBAL AND REGIONAL BRAIN BURDEN OF AMYLOID‐β IN COGNITIVELY NORMAL INDIVIDUALS AT RISK FOR AD: CROSS‐SECTIONAL AND LONGITUDINAL STUDIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P584, doi. 10.1016/j.jalz.2019.06.1256
- By:
- Publication type:
- Article
O1‐09‐05: SEXUAL DIMORPHISM IN PLASMA BETA‐SECRETASE 1 CONCENTRATIONS IN COGNITIVELY NORMAL INDIVIDUALS AT RISK FOR AD: CROSS‐SECTIONAL AND LONGITUDINAL STUDIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P218, doi. 10.1016/j.jalz.2019.06.4569
- By:
- Publication type:
- Article
Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, n. 7, p. 940, doi. 10.1016/j.jalz.2019.03.006
- By:
- Publication type:
- Article
Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, n. 6, p. 764, doi. 10.1016/j.jalz.2019.03.009
- By:
- Publication type:
- Article