Works matching AU Potempa, Jan

Results: 176

The trapping of live neutrophils by macrophages during infection.

Published in:

Cell Death & Disease, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41419-025-07808-5

By:

Cooper, Kelley N.;
Terekhova, Marina;
Potempa, Barbara;
D’Aubeterre, Ana;
Timbol, Jerome;
Chen, Si An;
Dufour, Antoine;
Jin, Shunying;
Artyomov, Maxim N.;
Potempa, Jan;
Bagaitkar, Juhi

Publication type:

Article

The trapping of live neutrophils by macrophages during infection.

Published in:

Cell Death & Disease, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41419-025-07808-5

By:

Cooper, Kelley N.;
Terekhova, Marina;
Potempa, Barbara;
D’Aubeterre, Ana;
Timbol, Jerome;
Chen, Si An;
Dufour, Antoine;
Jin, Shunying;
Artyomov, Maxim N.;
Potempa, Jan;
Bagaitkar, Juhi

Publication type:

Article

Antibodies to Porphyromonas gingivalis Are Increased in Patients with Severe Periodontitis, and Associate with Presence of Specific Autoantibodies and Myocardial Infarction.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 4, p. N.PAG, doi. 10.3390/jcm11041008

By:

de Vries, Charlotte;
Ruacho, Guillermo;
Kindstedt, Elin;
Potempa, Barbara Aleksandra;
Potempa, Jan;
Klinge, Björn;
Lundberg, Pernilla;
Svenungsson, Elisabet;
Lundberg, Karin

Publication type:

Article

Citrullination of C1-inhibitor as a mechanism of impaired complement regulation in rheumatoid arthritis.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1203506

By:

Martin, Myriam;
Nilsson, Sara C.;
Eikrem, David;
Fromell, Karin;
Scavenius, Carsten;
Vogt, Leonie M.;
Bielecka, Ewa;
Potempa, Jan;
Enghild, Jan J.;
Nilsson, Bo;
Ekdahl, Kristina N.;
Kapetanovic, Meliha C.;
Blom, Anna M.

Publication type:

Article

Antibodies against Porphyromonas gingivalis in serum and saliva and their association with rheumatoid arthritis and periodontitis. Data from two rheumatoid arthritis cohorts in Sweden.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1183194

By:

Svärd, Anna;
Kastbom, Alf;
Ljungberg, Karin Roos;
Potempa, Barbara;
Potempa, Jan;
Persson, G. Rutger;
Renvert, Stefan;
Berglund, Johan Sanmartin;
Söderlin, Maria K.

Publication type:

Article

TIMP‐1 association with collagen type I overproduction in hereditary gingival fibromatosis.

Published in:

Oral Diseases, 2018, v. 24, n. 8, p. 1581, doi. 10.1111/odi.12938

By:

Gawron, Katarzyna;
Ochała‐Kłos, Anna;
Nowakowska, Zuzanna;
Bereta, Grzegorz;
Łazarz‐Bartyzel, Katarzyna;
Grabiec, Aleksander M.;
Plakwicz, Paweł;
Górska, Renata;
Fertala, Andrzej;
Chomyszyn‐Gajewska, Maria;
Potempa, Jan

Publication type:

Article

Treatment of severe periodontitis may improve clinical disease activity in otherwise treatment-refractory rheumatoid arthritis patients.

Published in:

Rheumatology, 2020, v. 59, n. 1, p. 243, doi. 10.1093/rheumatology/kez287

By:

Möller, Burkhard;
Bender, Philip;
Eick, Sigrun;
Kuchen, Stefan;
Maldonado, Alejandra;
Potempa, Jan;
Reichenbach, Stephan;
Sculean, Anton;
Schwenzer, Anja;
Villiger, Peter M;
Wong, Alicia;
Midwood, Kim S

Publication type:

Article

Porphyromonas gingivalis Gingipains-Mediated Degradation of Plasminogen Activator Inhibitor-1 Leads to Delayed Wound Healing Responses in Human Endothelial Cells.

Published in:

Journal of Innate Immunity, 2022, v. 14, n. 4, p. 306, doi. 10.1159/000519737

By:

Song, Li-Ting;
Tada, Hiroyuki;
Nishioka, Takashi;
Nemoto, Eiji;
Imamura, Takahisa;
Potempa, Jan;
Li, Chang-Yi;
Matsushita, Kenji;
Sugawara, Shunji

Publication type:

Article

MCPIP-1, Alias Regnase-1, Controls Epithelial Inflammation by Posttranscriptional Regulation of IL-8 Production.

Published in:

Journal of Innate Immunity, 2016, v. 8, n. 6, p. 564, doi. 10.1159/000448038

By:

Dobosz, Ewelina;
Wilamowski, Mateusz;
Lech, Maciej;
Bugara, Beata;
Jura, Jolanta;
Potempa, Jan;
Koziel, Joanna

Publication type:

Article

Gingipains: Critical Factors in the Development of Aspiration Pneumonia Caused by Porphyromonas gingivalis.

Published in:

Journal of Innate Immunity, 2016, v. 8, n. 2, p. 185, doi. 10.1159/000441724

By:

Benedyk, Małgorzata;
Mydel, Piotr Mateusz;
Delaleu, Nicolas;
Płaza, Karolina;
Gawron, Katarzyna;
Milewska, aleksandra;
Maresz, Katarzyna;
Koziel, Joanna;
Pyrc, Krzysztof;
Potempa, Jan

Publication type:

Article

Porphyromonas gingivalis Gingipains Selectively Reduce CD14 Expression, Leading to Macrophage Hyporesponsiveness to Bacterial Infection.

Published in:

Journal of Innate Immunity, 2015, v. 7, n. 2, p. 127, doi. 10.1159/000365970

By:

Wilensky, asaf;
Tzach-Nahman, Rinat;
Potempa, Jan;
Shapira, Lior;
Nussbaum, Gabriel

Publication type:

Article

The Janus Face of α-Toxin: A Potent Mediator of Cytoprotection in Staphylococci-Infected Macrophages.

Published in:

Journal of Innate Immunity, 2015, v. 7, n. 2, p. 187, doi. 10.1159/000368048

By:

Koziel, Joanna;
Chmiest, Daniela;
Bryzek, Danuta;
Kmiecik, Katarzyna;
Mizgalska, Danuta;
Maciag-Gudowska, agnieszka;
Shaw, Lindsey N.;
Potempa, Jan

Publication type:

Article

Porphyromonas gingivalis Fimbriae Dampen P2X7-Dependent Interleukin-1β Secretion.

Published in:

Journal of Innate Immunity, 2014, v. 6, n. 6, p. 831, doi. 10.1159/000363338

By:

Morandini, ana Carolina;
Ramos-Junior, Erivan S.;
Potempa, Jan;
Nguyen, Ky-anh;
Oliveira, ana Carolina;
Bellio, Maria;
Ojcius, David M.;
Scharfstein, Julio;
Coutinho-Silva, Robson

Publication type:

Article

Staphylococcal Proteases Aid in Evasion of the Human Complement System.

Published in:

Journal of Innate Immunity, 2014, v. 6, n. 1, p. 31, doi. 10.1159/000351458

By:

Jusko, Monika;
Potempa, Jan;
Kantyka, Tomasz;
Bielecka, Ewa;
Miller, Halie K.;
Kalinska, Magdalena;
Dubin, Grzegorz;
Garred, Peter;
Shaw, Lindsey N.;
Blom, anna M.

Publication type:

Article

Staphylococcus aureus Proteases Degrade Lung Surfactant Protein A Potentially Impairing Innate Immunity of the Lung.

Published in:

Journal of Innate Immunity, 2013, v. 5, n. 3, p. 251, doi. 10.1159/000345417

By:

Kantyka, Tomasz;
Pyrc, Krzysztof;
Gruca, Milosz;
Smagur, Jan;
Plaza, Karolina;
Guzik, Krzysztof;
Zeglen, Slawomir;
Ochman, Marek;
Potempa, Jan

Publication type:

Article

Posttranslational Modifications in Innate Immunity.

Published in:

Journal of Innate Immunity, 2012, v. 4, n. 2, p. 119, doi. 10.1159/000336327

By:

Potempa, Jan

Publication type:

Article

Proteolytic Inactivation of LL-37 by Karilysin, a Novel Virulence Mechanism of Tannerella forsythia.

Published in:

Journal of Innate Immunity, 2010, v. 2, n. 3, p. 288, doi. 10.1159/000281881

By:

Koziel, Joanna;
Karim, Aabdulkarim Y.;
Przybyszewska, Kornelia;
Ksiazek, Miroslaw;
Rapala-Kozik, Maria;
Nguyen, Ky-Anh;
Potempa, Jan

Publication type:

Article

Corruption of Innate Immunity by Bacterial Proteases.

Published in:

Journal of Innate Immunity, 2009, v. 1, n. 2, p. 70, doi. 10.1159/000181144

By:

Potempa, Jan;
Pike, Robert N.

Publication type:

Article

A New Pathway of Staphylococcal Pathogenesis: Apoptosis-Like Death Induced by Staphopain B in Human Neutrophils and Monocytes.

Published in:

Journal of Innate Immunity, 2009, v. 1, n. 2, p. 98, doi. 10.1159/000181014

By:

Smagur, Jan;
Guzik, Krzysztof;
Magiera, Lukasz;
Bzowska, Malgorzata;
Gruca, Milosz;
Thøgersen, Ida B.;
Enghild, Jan J.;
Potempa, Jan

Publication type:

Article

High Molecular Weight Gingipains from Porphyromonas gingivalis Induce Cytokine Responses from Human Macrophage-Like Cells via a Nonproteolytic Mechanism.

Published in:

Journal of Innate Immunity, 2009, v. 1, n. 2, p. 109, doi. 10.1159/000181145

By:

Fitzpatrick, Rebecca E.;
Aprico, Andrea;
Wijeyewickrema, Lakshmi C.;
Pagel, Charles N.;
Wong, David M.;
Potempa, Jan;
Mackie, Eleanor J.;
Pike, Robert N.

Publication type:

Article

Bestatin as a treatment modality in experimental periodontitis.

Published in:

Journal of Periodontology, 2023, v. 94, n. 11, p. 1338, doi. 10.1002/JPER.22-0614

By:

Kaminska, Marta;
Benedyk‐Machaczka, Malgorzata;
Adamowicz, Karina;
Aliko, Ardita;
Drzazga, Kamila;
Słysz, Klaudia;
Bielecka, Ewa;
Potempa, Jan;
Mydel, Piotr

Publication type:

Article

Effects of statins on multispecies oral biofilm identify simvastatin as a drug candidate targeting Porphyromonas gingivalis.

Published in:

2019

By:

Kamińska, Marta;
Aliko, Ardita;
Hellvard, Annelie;
Bielecka, Ewa;
Binder, Veronika;
Marczyk, Agata;
Potempa, Jan;
Delaleu, Nicolas;
Kantyka, Tomasz;
Mydel, Piotr

Publication type:

journal article

Comparison of Gingival Crevicular Fluid Sampling Methods in Patients With Severe Chronic Periodontitis.

Published in:

Journal of Periodontology, 2011, v. 82, n. 7, p. 1051, doi. 10.1902/jop.2011.100565

By:

Guentsch, Arndt;
Kramesberger, Martin;
Sroka, Aneta;
Pfister, Wolfgang;
Potempa, Jan;
Eick, Sigrun

Publication type:

Article

Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold.

Published in:

EMBO Journal, 1999, v. 18, n. 20, p. 5453, doi. 10.1093/emboj/18.20.5453

By:

Eichinger, Andreas;
Beisel, Hans-Georg;
Jacob, Uwe;
Huber, Robert;
Medrano, Francisco-Javier;
Banbula, Agnieszka;
Potempa, Jan;
Travis, Jim;
Bode, Wolfram

Publication type:

Article

Inhibition of Tumor Necrosis Factor-α--Induced RANTES Secretion by Alkaline Protease in A549 Cells.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2005, v. 33, n. 5, p. 483, doi. 10.1165/rcmb.2005-0069OC

By:

Krunkosky, Thomas M.;
Keishi Maruo;
Potempa, Jan;
Jarrett, Carla L.;
Travis, James

Publication type:

Article

Intracellular Staphylococcus aureus employs the cysteine protease staphopain A to induce host cell death in epithelial cells.

Published in:

PLoS Pathogens, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.ppat.1009874

By:

Stelzner, Kathrin;
Boyny, Aziza;
Hertlein, Tobias;
Sroka, Aneta;
Moldovan, Adriana;
Paprotka, Kerstin;
Kessie, David;
Mehling, Helene;
Potempa, Jan;
Ohlsen, Knut;
Fraunholz, Martin J.;
Rudel, Thomas

Publication type:

Article

Protease-armed bacteria in the skin.

Published in:

Cell & Tissue Research, 2013, v. 351, n. 2, p. 325, doi. 10.1007/s00441-012-1355-2

By:

Koziel, Joanna;
Potempa, Jan

Publication type:

Article

Exhaled Nitric Oxide Reflects the Immune Reactions of the Airways in Early Rheumatoid Arthritis.

Published in:

Biomedicines, 2024, v. 12, n. 5, p. 964, doi. 10.3390/biomedicines12050964

By:

Weitoft, Tomas;
Rönnelid, Johan;
Lind, Anders;
de Vries, Charlotte;
Larsson, Anders;
Potempa, Barbara;
Potempa, Jan;
Kastbom, Alf;
Martinsson, Klara;
Lundberg, Karin;
Högman, Marieann

Publication type:

Article

Proteolysis of Gingival Keratinocyte Cell Surface Proteins by Gingipains Secreted From Porphyromonas gingivalis – Proteomic Insights Into Mechanisms Behind Tissue Damage in the Diseased Gingiva.

Published in:

Frontiers in Microbiology, 2020, v. 11, p. 1, doi. 10.3389/fmicb.2020.00722

By:

Hočevar, Katarina;
Vizovišek, Matej;
Wong, Alicia;
Kozieł, Joanna;
Fonović, Marko;
Potempa, Barbara;
Lamont, Richard J.;
Potempa, Jan;
Turk, Boris

Publication type:

Article

Shut-Down of Type IX Protein Secretion Alters the Host Immune Response to Tannerella forsythia and Porphyromonas gingivalis.

Published in:

Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.835509

By:

Braun, Matthias L.;
Tomek, Markus B.;
Grünwald-Gruber, Clemens;
Nguyen, Phuong Q.;
Bloch, Susanne;
Potempa, Jan S.;
Andrukhov, Oleh;
Schäffer, Christina

Publication type:

Article

Fighting an enemy within: cytoplasmic inhibitors of bacterial cysteine proteases.

Published in:

Molecular Microbiology, 2005, v. 57, n. 3, p. 605, doi. 10.1111/j.1365-2958.2005.04714.x

By:

Potempa, Jan;
Golonka, Ewa;
Filipek, Renata;
Shaw, Lindsey N.

Publication type:

Article

The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities.

Published in:

Molecular Microbiology, 2004, v. 54, n. 5, p. 1393, doi. 10.1111/j.1365-2958.2004.04357.x

By:

Sztukowska, Maryta;
Sroka, Aneta;
Bugno, Marcin;
Banbula, Agnieszka;
Takahashi, Yusuke;
Pike, Robert N.;
Genco, Caroline A.;
Travis, James;
Potempa, Jan

Publication type:

Article

Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases.

Published in:

Molecular Microbiology, 2003, v. 49, n. 4, p. 1051, doi. 10.1046/j.1365-2958.2003.03613.x

By:

Rzychon, Malgorzata;
Sabat, Artur;
Kosowska, Klaudia;
Potempa, Jan;
Dubin, Adam

Publication type:

Article

Role of rubrerythrin in the oxidative stress response of Porphyromonas gingivalis.

Published in:

Molecular Microbiology, 2002, v. 44, n. 2, p. 479, doi. 10.1046/j.1365-2958.2002.02892.x

By:

Sztukowska, Maryta;
Bugno, Marcin;
Potempa, Jan;
Travis, James;
Kurtz Jr, Donald M

Publication type:

Article

Selective inhibition of Porphyromonas gingivalis growth by a factor Xa inhibitor, DX-9065a.

Published in:

Journal of Periodontal Research, 2006, v. 41, n. 3, p. 171, doi. 10.1111/j.1600-0765.2005.00854.x

By:

Matsushita, Kenji;
Imamura, Takahisa;
Tancharoen, Salunya;
Tatsuyama, Syouko;
Tomikawa, Munehiro;
Travis, James;
Potempa, Jan;
Torii, Mitsuo;
Maruyama, Ikuro

Publication type:

Article

Breakdown of albumin and haemalbumin by the cysteine protease interpain A, an albuminase of Prevotella intermedia.

Published in:

BMC Microbiology, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12866-015-0516-3

By:

Byrne, Dominic P.;
Manandhar, Surya P.;
Potempa, Jan;
Smalley, John W.

Publication type:

Article

Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism.

Published in:

BMC Microbiology, 2009, v. 9, p. 1, doi. 10.1186/1471-2180-9-107

By:

Stathopoulou, Panagiota G.;
Galicia, Johnah C.;
Benakanakere, Manjunatha R.;
Garcia, Carlos A.;
Potempa, Jan;
Kinane, Denis F.

Publication type:

Article

Host cell-surface proteins as substrates of gingipains, the main proteases of Porphyromonas gingivalis.

Published in:

Biological Chemistry, 2018, v. 399, n. 12, p. 1353, doi. 10.1515/hsz-2018-0215

By:

Hočevar, Katarina;
Potempa, Jan;
Turk, Boris

Publication type:

Article

Mirolysin, a LysargiNase from Tannerella forsythia, proteolytically inactivates the human cathelicidin, LL-37.

Published in:

Biological Chemistry, 2017, v. 398, n. 3, p. 395, doi. 10.1515/hsz-2016-0267

By:

Koneru, Lahari;
Ksiazek, Miroslaw;
Waligorska, Irena;
Straczek, Anna;
Lukasik, Magdalena;
Madej, Mariusz;
Thøgersen, Ida B.;
Enghild, Jan J.;
Potempa, Jan

Publication type:

Article

Purification and characterisation of recombinant His-tagged RgpB gingipain from Porphymonas gingivalis.

Published in:

Biological Chemistry, 2015, v. 396, n. 4, p. 377, doi. 10.1515/hsz-2014-0304

By:

Veillard, Florian;
Potempa, Barbara;
Guo, Yonghua;
Ksiazek, Miroslaw;
Sztukowska, Maryta N.;
Houston, John A.;
Koneru, Lahari;
Nguyen, Ky-Anh;
Potempa, Jan

Publication type:

Article

Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia.

Published in:

Biological Chemistry, 2015, v. 396, n. 3, p. 261, doi. 10.1515/hsz-2014-0256

By:

Ksiazek, Miroslaw;
Karim, Abdulkarim Y.;
Bryzek, Danuta;
Enghild, Jan J.;
Thøgersen, Ida B.;
Koziel, Joanna;
Potempa, Jan

Publication type:

Article

The Staphylococcus aureus leucine aminopeptidase is localized to the bacterial cytosol and demonstrates a broad substrate range that extends beyond leucine.

Published in:

Biological Chemistry, 2013, v. 394, n. 6, p. 791, doi. 10.1515/hsz-2012-0308

By:

Carroll, Ronan K.;
Veillard, Florian;
Gagne, Danielle T.;
Lindenmuth, Jarrod M.;
Poreba, Marcin;
Drag, Marcin;
Potempa, Jan;
Shaw, Lindsey N.

Publication type:

Article

Gingipain aminopeptidase activities in Porphyromonas gingivalis.

Published in:

Biological Chemistry, 2012, v. 393, n. 12, p. 1471, doi. 10.1515/hsz-2012-0222

By:

Veillard, Florian;
Potempa, Barbara;
Poreba, Marcin;
Drag, Marcin;
Potempa, Jan

Publication type:

Article

Protease-dependent mechanisms of complement evasion by bacterial pathogens.

Published in:

Biological Chemistry, 2012, v. 393, n. 9, p. 873, doi. 10.1515/hsz-2012-0174

By:

Potempa, Michal;
Potempa, Jan

Publication type:

Article

Disruption of gingipain oligomerization into non-covalent cell-surface attached complexes.

Published in:

Biological Chemistry, 2012, v. 393, n. 9, p. 971, doi. 10.1515/hsz-2012-0175

By:

Sztukowska, Maryta;
Veillard, Florian;
Potempa, Barbara;
Bogyo, Matthew;
Enghild, Jan J.;
Thogersen, Ida B.;
Nguyen, Ky-Anh;
Potempa, Jan

Publication type:

Article

Inhibition of Staphylococcus aureus cysteine proteases by human serpin potentially limits staphylococcal virulence.

Published in:

Biological Chemistry, 2011, v. 392, n. 5, p. 483, doi. 10.1515/BC.2011.044

By:

Kantyka, Tomasz;
Plaza, Karolina;
Koziel, Joanna;
Florczyk, Danuta;
Stennicke, Hennig R.;
Thogersen, Ida B.;
Enghild, Jan J.;
Silverman, Gary A.;
Pak, Stephen C.;
Potempa, Jan

Publication type:

Article

Dentipain, a Streptococcus pyogenes IdeS protease homolog, is a novel virulence factor of Treponema denticola.

Published in:

Biological Chemistry, 2010, v. 391, n. 9, p. 1047, doi. 10.1515/BC.2010.113

By:

Ishihara, Kazuyuki;
Wawrzonek, Katarzyna;
Shaw, Lindesey N.;
Inagaki, Satoru;
Miyamoto, Meguru;
Potempa, Jan

Publication type:

Article

A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037.

Published in:

Biological Chemistry, 2010, v. 391, n. 1, p. 105, doi. 10.1515/BC.2010.009

By:

Karim, Abdulkarim Y.;
Kulczycka, Magdalena;
Kantyka, Tomasz;
Dubin, Grzegorz;
Jabaiah, Abeer;
Daugherty, Patrick S.;
Thogersen, Ida B.;
Enghild, Jan J.;
Nguyen, Ky-Anh;
Potempa, Jan

Publication type:

Article

Elafin is specifically inactivated by RgpB from Porphyromonas gingivalis by distinct proteolytic cleavage.

Published in:

Biological Chemistry, 2009, v. 390, n. 12, p. 1313, doi. 10.1515/BC.2009.136

By:

Kantyka, Tomasz;
Latendorf, Ties;
Wiedow, Oliver;
Bartels, Joachim;
Gläser, Regine;
Dubin, Grzegorz;
Schröder, Jens-Michael;
Potempa, Jan;
Meyer-Hoffert, Ulf

Publication type:

Article

Staphylococcal cysteine protease staphopain B (SspB) induces rapid engulfment of human neutrophils and monocytes by macrophages.

Published in:

Biological Chemistry, 2009, v. 390, n. 4, p. 361, doi. 10.1515/BC.2009.042

By:

Smagur, Jan;
Guzik, Krzysztof;
Bzowska, Malgorzata;
Kuzak, Mateusz;
Zarebski, Miroslaw;
Kantyka, Tomasz;
Walski, Michal;
Gajkowska, Barbara;
Potempa, Jan

Publication type:

Article