Works by Ponting, Chris P

Results: 122

Corrigendum: Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 272, doi. 10.1038/nsmb0315-272b

By:

Tan, Jennifer Y;
Vance, Keith W;
Varela, Miguel A;
Sirey, Tamara;
Watson, Lauren M;
Curtis, Helen J;
Marinello, Martina;
Alves, Sandro;
Steinkraus, Bruno R;
Cooper, Sarah;
Nesterova, Tatyana;
Brockdorff, Neil;
Fulga, Tudor A;
Brice, Alexis;
Sittler, Annie;
Oliver, Peter L;
Wood, Matthew J;
Ponting, Chris P;
Marques, Ana C

Publication type:

Article

Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 11, p. 955, doi. 10.1038/nsmb.2902

By:

Tan, Jennifer Y;
Vance, Keith W;
Varela, Miguel A;
Sirey, Tamara;
Watson, Lauren M;
Curtis, Helen J;
Marinello, Martina;
Alves, Sandro;
Steinkraus, Bruno R;
Cooper, Sarah;
Nesterova, Tatyana;
Brockdorff, Neil;
Fulga, Tudor A;
Brice, Alexis;
Sittler, Annie;
Oliver, Peter L;
Wood, Matthew J;
Ponting, Chris P;
Marques, Ana C

Publication type:

Article

Vasohibins: new transglutaminase-like cysteine proteases possessing a non-canonical Cys-His-Ser catalytic triad.

Published in:

Bioinformatics, 2016, v. 32, n. 10, p. 1441, doi. 10.1093/bioinformatics/btv761

By:

Sanchez-Pulido, Luis;
Ponting, Chris P.

Publication type:

Article

CGAT: computational genomics analysis toolkit.

Published in:

Bioinformatics, 2014, v. 30, n. 9, p. 1290, doi. 10.1093/bioinformatics/btt756

By:

Sims, David;
Ilott, Nicholas E.;
Sansom, Stephen N.;
Sudbery, Ian M.;
Johnson, Jethro S.;
Fawcett, Katherine A.;
Berlanga-Taylor, Antonio J.;
Luna-Valero, Sebastian;
Ponting, Chris P.;
Heger, Andreas

Publication type:

Article

Tiki, at the head of a new superfamily of enzymes.

Published in:

Bioinformatics, 2013, v. 29, n. 19, p. 2371, doi. 10.1093/bioinformatics/btt412

By:

Sanchez-Pulido, Luis;
Ponting, Chris P.

Publication type:

Article

GAT: a simulation framework for testing the association of genomic intervals.

Published in:

Bioinformatics, 2013, v. 29, n. 16, p. 2046, doi. 10.1093/bioinformatics/btt343

By:

Heger, Andreas;
Webber, Caleb;
Goodson, Martin;
Ponting, Chris P.;
Lunter, Gerton

Publication type:

Article

A common ancestry for BAP1 and Uch37 regulators.

Published in:

Bioinformatics, 2012, v. 28, n. 15, p. 1953, doi. 10.1093/bioinformatics/bts319

By:

Sanchez-Pulido, Luis;
Kong, Lesheng;
Ponting, Chris P.

Publication type:

Article

Cdc45: the missing RecJ ortholog in eukaryotes?

Published in:

Bioinformatics, 2011, v. 27, n. 14, p. 1885, doi. 10.1093/bioinformatics/btr332

By:

Sanchez-Pulido, Luis;
Ponting, Chris P.

Publication type:

Article

Meisetz and the birth of the KRAB motif.

Published in:

Bioinformatics, 2006, v. 22, n. 23, p. 2841, doi. 10.1093/bioinformatics/btl498

By:

Birtle, Zoë;
Ponting, Chris P.

Publication type:

Article

A novel domain suggests a ciliary function for ASPM, a brain size determining gene.

Published in:

Bioinformatics, 2006, v. 22, n. 9, p. 1031, doi. 10.1093/bioinformatics/btl022

By:

Chris P. Ponting

Publication type:

Article

Sequencing depth and coverage: key considerations in genomic analyses.

Published in:

Nature Reviews Genetics, 2014, v. 15, n. 2, p. 121, doi. 10.1038/nrg3642

By:

Sims, David;
Sudbery, Ian;
Ilott, Nicholas E.;
Heger, Andreas;
Ponting, Chris P.

Publication type:

Article

A gene expression signature in developing Purkinje cells predicts autism and intellectual disability co-morbidity status.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37284-1

By:

Clifford, Harry;
Dulneva, Anna;
Ponting, Chris P.;
Haerty, Wilfried;
Becker, Esther B. E.

Publication type:

Article

Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02120

By:

Handel, Adam E.;
Shikama-Dorn, Noriko;
Zhanybekova, Saule;
Maio, Stefano;
Graedel, Annina N.;
Zuklys, Saulius;
Ponting, Chris P.;
Holländer, Georg A.

Publication type:

Article

EYS, encoding an ortholog of Drosophila spacemaker, is mutated in autosomal recessive retinitis pigmentosa.

Published in:

Nature Genetics, 2008, v. 40, n. 11, p. 1285, doi. 10.1038/ng.241

By:

Abd El-Aziz, Mai M;
Barragan, Isabel;
O'Driscoll, Ciara A;
Goodstadt, Leo;
Prigmore, Elena;
Borrego, Salud;
Mena, Marcela;
Pieras, Juan I;
El-Ashry, Mohamed F;
Safieh, Leen Abu;
Shah, Amna;
Cheetham, Michael E;
Carter, Nigel P;
Chakarova, Christina;
Ponting, Chris P;
Bhattacharya, Shomi S;
Antinolo, Guillermo

Publication type:

Article

Positional cloning of a novel gene influencing asthma from Chromosome 2q14.

Published in:

Nature Genetics, 2003, v. 35, n. 3, p. 258, doi. 10.1038/ng1256

By:

Abecasis, Gonçalo;
Broxholme, John;
Ponting, Chris P.;
Bhattacharyya, Sumit;
Tinsley, Jon;
Zhang, Youming;
Holt, Richard;
Jones, E Yvonne;
Lench, Nick;
Carey, Alisoun;
Jones, Helene;
Dickens, Nicholas J.;
Dimon, Claire;
Nicholls, Rosie;
Baker, Crystal;
Luzheng Xue;
Townsend, Elizabeth;
Kabesch, Michael;
Weiland, Stephan K.;
Carr, David

Publication type:

Article

Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma.

Published in:

Nature Genetics, 2003, v. 34, n. 2, p. 181, doi. 10.1038/ng1166

By:

Zhang, Youming;
Leaves, Nicholas I;
Anderson, Gavin G;
Ponting, Chris P;
Broxholme, John;
Holt, Richard;
Edser, Pauline;
Bhattacharyya, Sumit;
Dunham, Andy;
Adcock, Ian M;
Pulleyn, Louise;
Barnes, Peter J;
Harper, John I;
Abecasis, Goncalo;
Cardon, Lon;
White, Melanie;
Burton, John;
Matthews, Lucy;
Mott, Richard

Publication type:

Article

More than 1,000 putative new human signalling proteins revealed by EST data mining.

Published in:

Nature Genetics, 2000, v. 25, n. 2, p. 201, doi. 10.1038/76069

By:

Schultz, Jörg;
Doerks, Tobias;
Ponting, Chris P.;
Copley, Richard R.;
Bork, Peer

Publication type:

Article

Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence.

Published in:

BMC Genomics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2164-14-95

By:

Rands, Chris M.;
Darling, Aaron;
Fujita, Matthew;
Kong, Lesheng;
Webster, Matthew T.;
Clabaut, Céline;
Emes, Richard D.;
Heger, Andreas;
Meader, Stephen;
Hawkins, Michael Brent;
Eisen, Michael B.;
Teiling, Clotilde;
Affourtit, Jason;
Boese, Benjamin;
Grant, Peter R.;
Grant, Barbara Rosemary;
Eisen, Jonathan A.;
Abzhanov, Arhat;
Ponting, Chris P.

Publication type:

Article

Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-977

By:

Rajan, Prabhakar;
Stockley, Jacqueline;
Sudbery, Ian M.;
Fleming, Janis T.;
Hedley, Ann;
Kalna, Gabriela;
Sims, David;
Ponting, Chris P.;
Heger, Andreas;
Robson, Craig N.;
McMenemin, Rhona M.;
Pedley, Ian D.;
Hing Y. Leung

Publication type:

Article

Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer.

Published in:

2014

By:

Rajan, Prabhakar;
Stockley, Jacqueline;
Sudbery, Ian M;
Fleming, Janis T;
Hedley, Ann;
Kalna, Gabriela;
Sims, David;
Ponting, Chris P;
Heger, Andreas;
Robson, Craig N;
McMenemin, Rhona M;
Pedley, Ian D;
Leung, Hing Y

Publication type:

journal article

Identification and functional analysis of an ovarian form of the egg activation factor phospholipase C zeta (PLCζ) in pufferfish.

Published in:

Molecular Reproduction & Development, 2011, v. 78, n. 1, p. 48, doi. 10.1002/mrd.21262

By:

Coward, Kevin;
Ponting, Chris P.;
Zhang, Nan;
Young, Claire;
Huang, Chang-Jen;
Chou, Chih-Ming;
Kashir, Junaid;
Fissore, Rafael A.;
Parrington, John

Publication type:

Article

CHROMA: consensus-based colouring of multiple alignments for publication.

Published in:

Bioinformatics, 2001, v. 17, n. 9, p. 845, doi. 10.1093/bioinformatics/17.9.845

By:

Goodstadt, Leo;
Ponting, Chris P.

Publication type:

Article

MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression.

Published in:

Journal of Cell Biology, 2013, v. 200, n. 6, p. 773, doi. 10.1083/jcb.201207050

By:

Mei Zhu;
Settele, Florian;
Kotak, Sachin;
Sanchez-Pulido, Luis;
Ehret, Lena;
Ponting, Chris P.;
Gönczy, Pierre;
Hoffmann, Ingrid

Publication type:

Article

The long and the short of RNA maps.

Published in:

BioEssays, 2007, v. 29, n. 11, p. 1077, doi. 10.1002/bies.20669

By:

Ponjavic, Jasmina;
Ponting, Chris P.

Publication type:

Article

The RFTS Domain of Raf2 Is Required for Cul4 Interaction and Heterochromatin Integrity in Fission Yeast.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104161

By:

White, Sharon A.;
Buscaino, Alessia;
Sanchez-Pulido, Luis;
Ponting, Chris P.;
Nowicki, Matthew W.;
Allshire, Robin C.

Publication type:

Article

Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells.

Published in:

EMBO Journal, 2020, v. 39, n. 1, p. N.PAG, doi. 10.15252/embj.2019101828

By:

Dhalla, Fatima;
Baran‐Gale, Jeanette;
Maio, Stefano;
Chappell, Lia;
Holländer, Georg A;
Ponting, Chris P

Publication type:

Article

The long non-coding RNA Paupar promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis.

Published in:

EMBO Journal, 2018, v. 37, n. 10, p. 1, doi. 10.15252/embj.201798219

By:

Pavlaki, Ioanna;
Alammari, Farah;
Sun, Bin;
Clark, Neil;
Sirey, Tamara;
Sheena Lee;
Woodcock, Dan J.;
Ponting, Chris P.;
Szele, Francis G.;
Vance, Keith W.

Publication type:

Article

Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus.

Published in:

BMC Biology, 2011, v. 9, n. 1, p. 14, doi. 10.1186/1741-7007-9-14

By:

Blair, Helen J.;
Tompson, Stuart;
Yu-Ning Liu;
Campbell, Jennifer;
MacArthur, Katie;
Ponting, Chris P.;
Ruiz-Perez, Victor L.;
Goodship, Judith A.

Publication type:

Article

Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits.

Published in:

PLoS Genetics, 2020, v. 16, n. 7, p. 1, doi. 10.1371/journal.pgen.1008785

By:

Bretherick, Andrew D.;
Canela-Xandri, Oriol;
Joshi, Peter K.;
Clark, David W.;
Rawlik, Konrad;
Boutin, Thibaud S.;
Zeng, Yanni;
Amador, Carmen;
Navarro, Pau;
Rudan, Igor;
Wright, Alan F.;
Campbell, Harry;
Vitart, Veronique;
Hayward, Caroline;
Wilson, James F.;
Tenesa, Albert;
Ponting, Chris P.;
Baillie, J. Kenneth;
Haley, Chris

Publication type:

Article

TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease.

Published in:

Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00439

By:

Sanchez-Pulido, Luis;
Ponting, Chris P.;
Houten, Sander Michel;
Tarugi, Patrizia

Publication type:

Article

Genetic risk factors of ME/CFS: a critical review.

Published in:

Human Molecular Genetics, 2020, v. 29, n. R1, p. R117, doi. 10.1093/hmg/ddaa169

By:

Dibble, Joshua J;
McGrath, Simon J;
Ponting, Chris P

Publication type:

Article

Identification of genetic variants affecting vitamin D receptor binding and associations with autoimmune disease.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 11, p. 2164, doi. 10.1093/hmg/ddx092

By:

Gallone, Giuseppe;
Haerty, Wilfried;
Disanto, Giulio;
Ramagopalan, Sreeram V.;
Ponting, Chris P.;
Berlanga-Taylor, Antonio J.

Publication type:

Article

Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 1, p. 79, doi. 10.1093/hmg/ddw369

By:

Handel, Adam E.;
Gallone, Giuseppe;
Cader, M. Zameel;
Ponting, Chris P.

Publication type:

Article

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 5, p. 989, doi. 10.1093/hmg/ddv637

By:

Handel, Adam E.;
Chintawar, Satyan;
Lalic, Tatjana;
Whiteley, Emma;
Vowles, Jane;
Giustacchini, Alice;
Argoud, Karene;
Sopp, Paul;
Nakanishi, Mahito;
Bowden, Rory;
Cowley, Sally;
Newey, Sarah;
Akerman, Colin;
Ponting, Chris P.;
Cader, M. Zameel

Publication type:

Article

Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla.

Published in:

European Journal of Immunology, 2016, v. 46, n. 4, p. 846, doi. 10.1002/eji.201545995

By:

Mayer, Carlos E.;
Žuklys, Saulius;
Zhanybekova, Saule;
Ohigashi, Izumi;
Teh, Hong‐Ying;
Sansom, Stephen N.;
Shikama‐Dorn, Noriko;
Hafen, Katrin;
Macaulay, Iain C.;
Deadman, Mary E.;
Ponting, Chris P.;
Takahama, Yousuke;
Holländer, Georg A.

Publication type:

Article

The phenotypic spectrum of Xia‐Gibbs syndrome.

Published in:

American Journal of Medical Genetics. Part A, 2018, v. 176, n. 6, p. 1315, doi. 10.1002/ajmg.a.38699

By:

Jiang, Yunyun;
Wangler, Michael F.;
McGuire, Amy L.;
Lupski, James R.;
Posey, Jennifer E.;
Khayat, Michael M.;
Murdock, David R.;
Sanchez‐Pulido, Luis;
Ponting, Chris P.;
Xia, Fan;
Hunter, Jill V.;
Meng, Qingchang;
Murugan, Mullai;
Gibbs, Richard A.

Publication type:

Article

High order expression dependencies finely resolve cryptic states and subtypes in single cell data.

Published in:

Molecular Systems Biology, 2025, v. 21, n. 2, p. 173, doi. 10.1038/s44320-024-00074-1

By:

Jansma, Abel;
Yao, Yuelin;
Wolfe, Jareth;
Del Debbio, Luigi;
Beentjes, Sjoerd V;
Ponting, Chris P;
Khamseh, Ava

Publication type:

Article

Phylogenetic Reconstruction of Orthology, Paralogy, and Conserved Synteny for Dog and Human.

Published in:

PLoS Computational Biology, 2006, v. 2, n. 9, p. e133, doi. 10.1371/journal.pcbi.0020133

By:

Goodstadt, Leo;
Ponting, Chris P.

Publication type:

Article

Genome-Wide Identification of Human Functional DNA Using a Neutral Indel Model.

Published in:

PLoS Computational Biology, 2006, v. 2, n. 1, p. e5, doi. 10.1371/journal.pcbi.0020005

By:

Lunter, Gerton;
Ponting, Chris P.;
Hein, Jotun

Publication type:

Article

Refining the domain architecture model of the replication origin firing factor Treslin/TICRR.

Published in:

Life Science Alliance, 2022, v. 5, n. 5, p. 1, doi. 10.26508/lsa.202101088

By:

Ferreira, Pedro;
Sanchez-Pulido, Luis;
Marko, Anika;
Ponting, Chris P.;
Boos, Dominik

Publication type:

Article

Variable Strength of Translational Selection Among 12 Drosophila Species.

Published in:

Genetics, 2007, v. 177, n. 3, p. 1337, doi. 10.1534/genetics.107.070466

By:

Heger, Andreas;
Ponting, Chris P.

Publication type:

Article

Whole-exome sequencing of 228 patients with sporadic Parkinson's disease.

Published in:

Scientific Reports, 2017, p. 41188, doi. 10.1038/srep41188

By:

Sandor, Cynthia;
Honti, Frantisek;
Haerty, Wilfried;
Szewczyk-Krolikowski, Konrad;
Tomlinson, Paul;
Evetts, Sam;
Millin, Stephanie;
Keane, Thomas;
McCarthy, Shane A.;
Durbin, Richard;
Talbot, Kevin;
Hu, Michele;
Webber, Caleb;
Ponting, Chris P.;
Wade-Martins, Richard

Publication type:

Article

Characterization of a gene encoding Survival Motor Neuron (SMN)-related protein, a constituent of the spliceosome complex.

Published in:

Human Molecular Genetics, 1998, v. 7, n. 13, doi. 10.1093/hmg/7.13.2149

By:

Talbot, Kevin;
Miguel‐Aliaga, Irene;
Mohaghegh, Payam;
Ponting, Chris P.;
Davies, Kay E.

Publication type:

Article

Transcriptional dynamics of pluripotent stem cell-derived endothelial cell differentiation revealed by single-cell RNA sequencing.

Published in:

European Heart Journal, 2020, v. 41, n. 9, p. 1024, doi. 10.1093/eurheartj/ehz351

By:

McCracken, Ian R;
Taylor, Richard S;
Kok, Fatma O;
de la Cuesta, Fernando;
Dobie, Ross;
Henderson, Beth E P;
Mountford, Joanne C;
Caudrillier, Axelle;
Henderson, Neil C;
Ponting, Chris P;
Baker, Andrew H

Publication type:

Article

The Reality of Pervasive Transcription.

Published in:

2011

By:

Clark, Michael B.;
Amaral, Paulo P.;
Schlesinger, Felix J.;
Dinger1, Marcel E.;
Taft, Ryan J.;
Rinn, John L.;
Ponting, Chris P.;
Stadler, Peter F.;
Morris, Kevin V.;
Morillon, Antonin;
Rozowsky, Joel S.;
Gerstein, Mark B.;
Wahlestedt, Claes;
Hayashizaki, Yoshihide;
Carninci, Piero;
Gingeras, Thomas R.;
Mattick, John S.

Publication type:

Opinion

OAF: a new member of the BRICHOS family.

Published in:

Bioinformatics Advances, 2022, v. 2, n. 1, p. 1, doi. 10.1093/bioadv/vbac087

By:

Sanchez-Pulido, Luis;
Ponting, Chris P

Publication type:

Article

PERCC1, a new member of the Yap/TAZ/FAM181 transcriptional co-regulator family.

Published in:

Bioinformatics Advances, 2022, v. 2, n. 1, p. 1, doi. 10.1093/bioadv/vbac008

By:

Sanchez-Pulido, Luis;
Jia, Siyang;
Hansen, Carsten Gram;
Ponting, Chris P

Publication type:

Article

The functional repertoires of metazoan genomes.

Published in:

2008

By:

Ponting, Chris P.

Publication type:

journal article

Issues in predicting protein function from sequence.

Published in:

Briefings in Bioinformatics, 2001, v. 2, n. 1, p. 19, doi. 10.1093/bib/2.1.19

By:

Ponting, Chris P.

Publication type:

Article

Structure and evolutionary history of DISC1.

Published in:

Human Molecular Genetics, 2011, v. 20, n. R2, p. R175, doi. 10.1093/hmg/ddr374

By:

Sanchez-Pulido, Luis;
Ponting, Chris P.

Publication type:

Article