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Insulin secretory responses to rising and falling glucose concentrations are delayed in subjects with impaired glucose tolerance.
Published in:
Diabetologia, 2002, v. 45, n. 4, p. 509, doi. 10.1007/s00125-002-0776-y
By:
- Ehrmann, D. A.;
- Breda, E.;
- Cavaghan, M. K.;
- Bajramovic, S.;
- Imperial, J.;
- Toffolo, G.;
- Cobelli, C.;
- Polonsky, K. S.
Publication type:
Article
Pdx1 and other factors that regulate pancreatic β-cell survival.
Published in:
Diabetes, Obesity & Metabolism, 2009, v. 11, p. 30, doi. 10.1111/j.1463-1326.2009.01121.x
By:
- Fujimoto, K.;
- Polonsky, K. S.
Publication type:
Article
Variable deterioration in cortical function during insulin-induced hypoglycemia.
Published in:
1985
By:
- Herold, Kevan C.;
- Polonsky, Kenneth S.;
- Cohen, Robert M.;
- Levy, Jerre;
- Douglas, Frank;
- Herold, K C;
- Polonsky, K S;
- Cohen, R M;
- Levy, J;
- Douglas, F
Publication type:
journal article
Glucose counterregulation in patients after pancreatectomy. Comparison with other clinical forms of diabetes.
Published in:
1984
By:
- Polonsky, K S;
- Herold, K C;
- Gilden, J L;
- Bergenstal, R M;
- Fang, V S;
- Moossa, A R;
- Jaspan, J B
Publication type:
journal article
Lack of glucagon response to hypoglycemia in type I diabetics after long-term optimal therapy with a continuous subcutaneous insulin infusion pump.
Published in:
1983
By:
- Bergenstal, R. M.;
- Polonsky, K. S.;
- Pons, G.;
- Jaspan, J. B.;
- Rubenstein, A. H.
Publication type:
journal article
Hepatic extraction of plasma immunoreactive glucagon components. Predilection for 3500-dalton glucagon metabolism by the liver.
Published in:
1981
By:
- Jaspan, J. B.;
- Polonsky, K. S.;
- Röjdmark, S.;
- Ishida, T.;
- Field, J. B.;
- Rubenstein, A. H.;
- Röjdmark, S
Publication type:
journal article
Hypoglycemia due to surreptitious injection of insulin. Identification of insulin species by high-performance liquid chromatography.
Published in:
1991
By:
- Given, B D;
- Ostrega, D M;
- Polonsky, K S;
- Baldwin, D Jr;
- Kelley, R I;
- Rubenstein, A H
Publication type:
journal article
Does tight glucose control enhance brain sensitivity to low glucose?
Published in:
1991
By:
- Herold, Kevan C.;
- Polonsky, Kenneth S.;
- Herold, K C;
- Polonsky, K S
Publication type:
Editorial
Effect of temporal distribution of calories on diurnal patterns of glucose levels and insulin secretion in NIDDM.
Published in:
1990
By:
- Beebe, Christine A.;
- Van Cauter, Eve;
- Shapiro, E. Timothy;
- Tillil, Hartmut;
- Lyons, Rachel;
- Rubenstein, Arthur H.;
- Polonsky, Kenneth S.;
- Beebe, C A;
- Van Cauter, E;
- Shapiro, E T;
- Tillil, H;
- Lyons, R;
- Rubenstein, A H;
- Polonsky, K S
Publication type:
journal article
Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.
Published in:
2001
By:
- Shih, David Q.;
- Screenan, Seamus;
- Munoz, Karla N.;
- Philipson, Lou;
- Pontoglio, Marco;
- Yaniv, Moshe;
- Polonsky, Kenneth S.;
- Stoffel, Markus;
- Shih, D Q;
- Screenan, S;
- Munoz, K N;
- Philipson, L;
- Pontoglio, M;
- Yaniv, M;
- Polonsky, K S;
- Stoffel, M
Publication type:
journal article
Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes.
Published in:
2001
By:
- Gautier, Jean-Francois;
- Wilson, Charlton;
- Weyer, Christian;
- Mott, Dave;
- Knowler, William C.;
- Cavaghan, Melissa;
- Polonsky, Kenneth S.;
- Bogardus, Clifton;
- Pratley, Richard E.;
- Gautier, J F;
- Wilson, C;
- Weyer, C;
- Mott, D;
- Knowler, W C;
- Cavaghan, M;
- Polonsky, K S;
- Bogardus, C;
- Pratley, R E
Publication type:
journal article
Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity.
Published in:
2001
By:
- Breda, Elena;
- Cavaghan, Melissa K.;
- Toffolo, Gianna;
- Polonsky, Kenneth S.;
- Cobelli, Claudio;
- Breda, E;
- Cavaghan, M K;
- Toffolo, G;
- Polonsky, K S;
- Cobelli, C
Publication type:
journal article
Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes.
Published in:
2000
By:
- Hollingdal, Malene;
- Juhl, Claus B.;
- Pincus, Steven M.;
- Sturis, Jeppe;
- Veldhuis, Johannes D.;
- Polonsky, Kenneth S.;
- Porksen, Niels;
- Schmitz, Ole;
- Hollingdal, M;
- Juhl, C B;
- Pincus, S M;
- Sturis, J;
- Veldhuis, J D;
- Polonsky, K S;
- Pørksen, N;
- Schmitz, O
Publication type:
journal article
Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.
Published in:
1999
By:
- Sreenan, Seamus;
- Pick, Anthony J.;
- Levisetti, Matteo;
- Baldwin, Aaron C.;
- Pugh, William;
- Polonsky, Kenneth S.;
- Sreenan, S;
- Pick, A J;
- Levisetti, M;
- Baldwin, A C;
- Pugh, W;
- Polonsky, K S
Publication type:
journal article
Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice.
Published in:
1998
By:
- Sreenan, Seamus K.;
- Cockburn, Brian N.;
- Baldwin, Aaron C.;
- Ostrega, Diane M.;
- Levisetti, Matteo;
- Grupe, Andrew;
- Bell, Graeme I.;
- Stewart, Timothy A.;
- Roe, Michael W.;
- Polonsky, Kenneth S.;
- Sreenan, S K;
- Cockburn, B N;
- Baldwin, A C;
- Ostrega, D M;
- Levisetti, M;
- Grupe, A;
- Bell, G I;
- Stewart, T A;
- Roe, M W;
- Polonsky, K S
Publication type:
journal article
Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance.
Published in:
1998
By:
- Byrne, Maria M.;
- Gliem, Katja;
- Wank, Uwe;
- Arnold, Rudolf;
- Katschinski, Martin;
- Polonsky, Kenneth S.;
- Goke, Burkhard;
- Byrne, M M;
- Gliem, K;
- Wank, U;
- Arnold, R;
- Katschinski, M;
- Polonsky, K S;
- Göke, B
Publication type:
journal article
Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.
Published in:
1998
By:
- Pick, Anthony;
- Clark, Joshua;
- Kubstrup, Christian;
- Levisetti, Matteo;
- Pugh, William;
- Bonner-Weir, Susan;
- Polonsky, Kenneth S.;
- Pick, A;
- Clark, J;
- Kubstrup, C;
- Levisetti, M;
- Pugh, W;
- Bonner-Weir, S;
- Polonsky, K S
Publication type:
journal article
Diminished insulin and glucagon secretory responses to arginine in nondiabetic subjects with a mutation in the hepatocyte nuclear factor-4alpha/MODY1 gene.
Published in:
1997
By:
- Herman, William H.;
- Fajans, Stefan S.;
- Smith, Maria J.;
- Polonsky, Kenneth S.;
- Bell, Graeme I.;
- Halter, Jeffrey B.;
- Herman, W H;
- Fajans, S S;
- Smith, M J;
- Polonsky, K S;
- Bell, G I;
- Halter, J B
Publication type:
journal article
Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes.
Published in:
1997
By:
- Cockburn, Brian N.;
- Ostrega, Diane M.;
- Sturis, Jeppe;
- Kubstrup, Christian;
- Polonsky, Kenneth S.;
- Bell, Graeme I.;
- Cockburn, B N;
- Ostrega, D M;
- Sturis, J;
- Kubstrup, C;
- Polonsky, K S;
- Bell, G I
Publication type:
journal article
Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats.
Published in:
1996
By:
- MacDonald, Michael J.;
- Jiping Tang;
- Polonsky, Kenneth S.;
- MacDonald, M J;
- Tang, J;
- Polonsky, K S
Publication type:
journal article
Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.
Published in:
1995
By:
- Tokuyama Y;
- Sturis J;
- DePaoli AM;
- Takeda J;
- Stoffel M;
- Tang J;
- Sun X;
- Polonsky KS;
- Bell GI;
- Tokuyama, Y;
- Sturis, J;
- DePaoli, A M;
- Takeda, J;
- Stoffel, M;
- Tang, J;
- Sun, X;
- Polonsky, K S;
- Bell, G I
Publication type:
journal article
Altered insulin secretory responses to glucose in subjects with a mutation in the MODY1 gene on chromosome 20.
Published in:
1995
By:
- Byrne, Maria M.;
- Sturis, Jeppe;
- Fajans, Stefan S.;
- Ortiz, F. Javier;
- Stoltz, Anjanette;
- Stoffel, Markus;
- Smith, Marla J.;
- Bell, Graeme I.;
- Halter, Jeffrey B.;
- Polonsky, Kenneth S.;
- Byrne, M M;
- Sturis, J;
- Fajans, S S;
- Ortiz, F J;
- Stoltz, A;
- Stoffel, M;
- Smith, M J;
- Bell, G I;
- Halter, J B;
- Polonsky, K S
Publication type:
journal article
Defects in insulin secretion and action in women with a history of gestational diabetes.
Published in:
1995
By:
- Ryan, Edmond A.;
- Imes, Sharleen;
- Dating Liu;
- McManus, Ruth;
- Finegood, Diane T.;
- Polonsky, Kenneth S.;
- Sturis, Jeppe;
- Ryan, E A;
- Imes, S;
- Liu, D;
- McManus, R;
- Finegood, D T;
- Polonsky, K S;
- Sturis, J
Publication type:
journal article
Alterations in immunoreactive proinsulin and insulin clearance induced by weight loss in NIDDM.
Published in:
1994
By:
- Polonsky, Kenneth S.;
- Gumbiner, Barry;
- Ostrega, Diane;
- Griver, Kay;
- Tager, Howard;
- Henry, Robert R.;
- Polonsky, K S;
- Gumbiner, B;
- Ostrega, D;
- Griver, K;
- Tager, H;
- Henry, R R
Publication type:
journal article
Compensation in pancreatic beta-cell function in subjects with glucokinase mutations.
Published in:
1994
By:
- Sturis, J;
- Kurland, I J;
- Byrne, M M;
- Mosekilde, E;
- Froguel, P;
- Pilkis, S J;
- Bell, G I;
- Polonsky, K S
Publication type:
journal article
Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree.
Published in:
1994
By:
- Herman, William H.;
- Fajans, Stefan S.;
- Ortiz, Francisco J.;
- Smith, Marla J.;
- Sturis, Jeppe;
- Bell, Graeme I.;
- Polonsky, Kenneth S.;
- Halter, Jeffrey B.;
- Herman, W H;
- Fajans, S S;
- Ortiz, F J;
- Smith, M J;
- Sturis, J;
- Bell, G I;
- Polonsky, K S;
- Halter, J B
Publication type:
journal article
Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion.
Published in:
1993
By:
- Iwashima, Yasunori;
- Pugh, William;
- Depaoli, Alex M.;
- Takeda, Jun;
- Seino, Susumu;
- Bell, Graeme I.;
- Polonsky, Kenneth S.;
- Iwashima, Y;
- Pugh, W;
- Depaoli, A M;
- Takeda, J;
- Seino, S;
- Bell, G I;
- Polonsky, K S
Publication type:
journal article
Oscillatory insulin secretion after pancreas transplant.
Published in:
1993
By:
- O'Meara, Niall M.;
- Sturis, Jeppe;
- Blackman, John D.;
- Byrne, Maria M.;
- Jaspan, Jonathan B.;
- Roland, Dianne C.;
- Thistlethwaite, J. Richard;
- Polonsky, Kenneth S.;
- O'Meara, N M;
- Sturis, J;
- Blackman, J D;
- Byrne, M M;
- Jaspan, J B;
- Roland, D C;
- Thistlethwaite, J R;
- Polonsky, K S
Publication type:
journal article
Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation.
Published in:
1992
By:
- Blackman, John D.;
- Polonsky, Kenneth S.;
- Jaspan, Jonathan B.;
- Sturis, Jeppe;
- Van Cauter, Eve;
- Thistlethwaite, J. Richard;
- Blackman, J D;
- Polonsky, K S;
- Jaspan, J B;
- Sturis, J;
- Van Cauter, E;
- Thistlethwaite, J R
Publication type:
journal article
Hypoglycemic thresholds for cognitive dysfunction in IDDM.
Published in:
1992
By:
- Blackman, John D.;
- Towle, Vernon L.;
- Sturis, Jeppe;
- Lewis, Gary F.;
- Spire, Jean-Paul;
- Polonsky, Kenneth S.;
- Blackman, J D;
- Towle, V L;
- Sturis, J;
- Lewis, G F;
- Spire, J P;
- Polonsky, K S
Publication type:
journal article
Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance.
Published in:
1992
By:
- Van Cauter, Eve;
- Mestrez, Fabienne;
- Sturis, Jeppe;
- Polonsky, Kenneth S.;
- Van Cauter, E;
- Mestrez, F;
- Sturis, J;
- Polonsky, K S
Publication type:
journal article
Hypoglycemic thresholds for cognitive dysfunction in humans.
Published in:
1990
By:
- Blackman, John D.;
- Towle, Vernon L.;
- Lewis, Gary F.;
- Spire, Jean-Paul;
- Polonsky, Kenneth S.;
- Blackman, J D;
- Towle, V L;
- Lewis, G F;
- Spire, J P;
- Polonsky, K S
Publication type:
journal article
Change in hexose distribution volume and fractional utilization of [18F]-2-deoxy-2-fluoro-D-glucose in brain during acute hypoglycemia in humans.
Published in:
1990
By:
- Shapiro, E. Timothy;
- Cooper, Malcolm;
- Chin-Tu Chen;
- Given, Bruce D.;
- Polonsky, Kenneth S.;
- Shapiro, E T;
- Cooper, M;
- Chen, C T;
- Given, B D;
- Polonsky, K S
Publication type:
journal article
Effects of aging on insulin secretion.
Published in:
1989
By:
- Gumbiner, Barry;
- Polonsky, Kenneth S.;
- Beltz, William F.;
- Wallace, Penny;
- Brechtel, Ginger;
- Fink, Raymond I.;
- Gumbiner, B;
- Polonsky, K S;
- Beltz, W F;
- Wallace, P;
- Brechtel, G;
- Fink, R I
Publication type:
journal article
Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans.
Published in:
1988
By:
- Tillil, Hartmut;
- Shapiro, E. Timothy;
- Rubenstein, Arthur H.;
- Galloway, John A.;
- Polonsky, Kenneth S.;
- Tillil, H;
- Shapiro, E T;
- Rubenstein, A H;
- Galloway, J A;
- Polonsky, K S
Publication type:
journal article
Reevaluation of urine C-peptide as measure of insulin secretion.
Published in:
1988
By:
- Tillil, Hartmut;
- Shapiro, E. Timothy;
- Given, Bruce D.;
- Rue, Paul;
- Rubenstein, Arthur H.;
- Galloway, John A.;
- Polonsky, Kenneth S.;
- Tillil, H;
- Shapiro, E T;
- Given, B D;
- Rue, P;
- Rubenstein, A H;
- Galloway, J A;
- Polonsky, K S
Publication type:
journal article
Insulin secretion and clearance. Comparison after oral and intravenous glucose.
Published in:
1987
By:
- Shapiro, E T;
- Tillil, H;
- Miller, M A;
- Frank, B H;
- Galloway, J A;
- Rubenstein, A H;
- Polonsky, K S
Publication type:
journal article
Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics.
Published in:
1987
By:
- Vølund, Aage;
- Polonsky, Kenneth S.;
- Bergman, Richard N.;
- Vølund, A;
- Polonsky, K S;
- Bergman, R N
Publication type:
journal article
Dynamics of insulin secretion in obesity and diabetes.
Published in:
International Journal of Obesity & Related Metabolic Disorders, 2000, v. 24, p. S29, doi. 10.1038/sj.ijo.0801273
By:
- Polonsky, K S
Publication type:
Article

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