Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.829063

By:

• Yang, Zheng;
• Loy, James;
• Poirson, Brian;
• Dai, Yanshan;
• Rajendran, Surendran;
• Xu, Shihua;
• Spires, Vanessa;
• Gururajan, Murali;
• Lin, Zheng;
• Arbanas, Jaren;
• Carl, Stephen;
• Pace, Samantha;
• Wang, Yun;
• Mehl, John;
• Vasudevan, Krishna;
• Spires, Thomas;
• Novosiadly, Ruslan;
• Coker, Shodeinde;
• Perez, Raymond;
• Covello, Kelly

Publication type:

Article