Found: 31
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A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene.
- Published in:
- 2021
- By:
- Publication type:
- Journal Article
Activation of Microglial Group III Metabotropic Glutamate Receptors Protects Neurons against Microglial Neurotoxicity.
- Published in:
- Journal of Neuroscience, 2003, v. 23, n. 6, p. 2150, doi. 10.1523/JNEUROSCI.23-06-02150.2003
- By:
- Publication type:
- Article
Haploinsufficiency of progranulin causes cell type specific impairments in PINK1/Parkin mitophagy.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.064195
- By:
- Publication type:
- Article
Emerging roles of p53 in glial cell function in health and disease.
- Published in:
- Glia, 2012, v. 60, n. 4, p. 515, doi. 10.1002/glia.22268
- By:
- Publication type:
- Article
KNOCKDOWN OF TREM2 EXPRESSION IN MICROGLIA: IMPLICATIONS FOR MIGRATION AND INFLAMMATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P397, doi. 10.1016/j.jalz.2016.06.750
- By:
- Publication type:
- Article
Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis.
- Published in:
- Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0575-4
- By:
- Publication type:
- Article
Soluble Fibrinogen Triggers Non-cell Autonomous ER Stress-Mediated Microglial-Induced Neurotoxicity.
- Published in:
- Frontiers in Cellular Neuroscience, 2018, p. N.PAG, doi. 10.3389/fncel.2018.00404
- By:
- Publication type:
- Article
Combined tissue and fluid proteomics with Tandem Mass Tags to identify low-abundance protein biomarkers of disease in peripheral body fluid: An Alzheimer's Disease case study.
- Published in:
- 2017
- By:
- Publication type:
- Other
Stimulation of Microglial Metabotropic Glutamate Receptor rnGlu2 Triggers Tumor Necrosis Factor α-Induced Neurotoxicity in Concert with Microglial-Derived Fas Ligand.
- Published in:
- Journal of Neuroscience, 2005, v. 25, n. 11, p. 2952, doi. 10.1523/JNEUROSCI.4456-04.2005
- By:
- Publication type:
- Article
Neuroprotection by safinamide in the 6-hydroxydopamine model of Parkinson's disease.
- Published in:
- Neuropathology & Applied Neurobiology, 2016, v. 42, n. 5, p. 423, doi. 10.1111/nan.12263
- By:
- Publication type:
- Article
Cannabinoids inhibit neurodegeneration in models of multiple sclerosis.
- Published in:
- 2003
- By:
- Publication type:
- journal article
A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC‐derived microglia.
- Published in:
- FASEB Journal, 2020, v. 34, n. 2, p. 2436, doi. 10.1096/fj.201902447R
- By:
- Publication type:
- Article
Human Huntington's disease pluripotent stem cell-derived microglia develop normally but are abnormally hyper-reactive and release elevated levels of reactive oxygen species.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions.
- Published in:
- Journal of Neurochemistry, 2012, v. 121, n. 2, p. 287, doi. 10.1111/j.1471-4159.2012.07659.x
- By:
- Publication type:
- Article
Inhibiting p53 pathways in microglia attenuates microglial-evoked neurotoxicity following exposure to Alzheimer peptides.
- Published in:
- Journal of Neurochemistry, 2010, v. 112, n. 2, p. 552, doi. 10.1111/j.1471-4159.2009.06485.x
- By:
- Publication type:
- Article
Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91207-1
- By:
- Publication type:
- Article
Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions.
- Published in:
- Human Molecular Genetics, 2020, v. 29, n. 19, p. 3224, doi. 10.1093/hmg/ddaa209
- By:
- Publication type:
- Article
Modulation of neurotransmitter release by dihydropyridine-sensitive calcium channels involves tyrosine phosphorylation.
- Published in:
- European Journal of Neuroscience, 1999, v. 11, n. 1, p. 279, doi. 10.1046/j.1460-9568.1999.00427.x
- By:
- Publication type:
- Article
The Plant-Derived Chalcone 2,2′,5′-Trihydroxychalcone Provides Neuroprotection against Toll-Like Receptor 4 Triggered Inflammation in Microglia.
- Published in:
- Oxidative Medicine & Cellular Longevity, 2015, v. 2015, p. 1, doi. 10.1155/2016/6301712
- By:
- Publication type:
- Article
Scavenger receptor control of chromogranin A-induced microglial stress and neurotoxic cascades
- Published in:
- FEBS Letters, 2009, v. 583, n. 21, p. 3461, doi. 10.1016/j.febslet.2009.09.049
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- Publication type:
- Article
Kainic Acid Inhibits the Synaptosomal Plasma Membrane Glutamate Carrier and Allows Glutamate Leakage from the Cytoplasm but Does Not Affect Glutamate Exocytosis.
- Published in:
- Journal of Neurochemistry, 1988, v. 50, n. 3, p. 745, doi. 10.1111/j.1471-4159.1988.tb02977.x
- By:
- Publication type:
- Article
Human myeloid progenitor glucocorticoid receptor activation causes genomic instability, type 1 IFN-response pathway activation and senescence in differentiated microglia; an early life stress model.
- Published in:
- Glia, 2023, v. 71, n. 4, p. 1036, doi. 10.1002/glia.24325
- By:
- Publication type:
- Article
Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss.
- Published in:
- Glia, 2023, v. 71, n. 4, p. 974, doi. 10.1002/glia.24318
- By:
- Publication type:
- Article
Novel potent liposome agonists of triggering receptor expressed on myeloid cells 2 phenocopy antibody treatment in cells.
- Published in:
- Glia, 2022, v. 70, n. 12, p. 2290, doi. 10.1002/glia.24252
- By:
- Publication type:
- Article
Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood–brain barrier damage.
- Published in:
- Journal of Neurochemistry, 2009, v. 109, n. 3, p. 694, doi. 10.1111/j.1471-4159.2009.05953.x
- By:
- Publication type:
- Article
Myelin-induced microglial neurotoxicity can be controlled by microglial metabotropic glutamate receptors.
- Published in:
- Journal of Neurochemistry, 2008, v. 106, n. 1, p. 442, doi. 10.1111/j.1471-4159.2008.05426.x
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- Publication type:
- Article
Pure albumin is a potent trigger of calcium signalling and proliferation in microglia but not macrophages or astrocytes.
- Published in:
- Journal of Neurochemistry, 2005, v. 92, n. 6, p. 1363, doi. 10.1111/j.1471-4159.2005.02982.x
- By:
- Publication type:
- Article
Microglia release activators of neuronal proliferation mediated by activation of mitogen-activated protein kinase, phosphatidylinositol-3-kinase/Akt and delta–Notch signalling cascades.
- Published in:
- Journal of Neurochemistry, 2004, v. 90, n. 1, p. 89, doi. 10.1111/j.1471-4159.2004.02461.x
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- Publication type:
- Article
Microglial Apoptosis Induced by Chromogranin A Is Mediated byMitochondrial Depolarisation and the Permeability Transition but Not byCytochrome c Release.
- Published in:
- Journal of Neurochemistry, 2000, v. 74, n. 4, p. 1452, doi. 10.1046/j.1471-4159.2000.0741452.x
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- Publication type:
- Article
Exocytotic and Nonexocytotic Modes of Glutamate Release from Cultured Cerebellar Granule Cells During Chemical Ischaemia.
- Published in:
- Journal of Neurochemistry, 1998, v. 70, n. 2, p. 806, doi. 10.1046/j.1471-4159.1998.70020806.x
- By:
- Publication type:
- Article
The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0280-6
- By:
- Publication type:
- Article