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Validating therapeutic targets through human genetics.
Published in:
Nature Reviews Drug Discovery, 2013, v. 12, n. 8, p. 581, doi. 10.1038/nrd4051
By:
- Plenge, Robert M.;
- Scolnick, Edward M.;
- Altshuler, David
Publication type:
Article
Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-35974-7
By:
- Sliz, Eeva;
- Tyrmi, Jaakko S.;
- Rahmioglu, Nilufer;
- Zondervan, Krina T.;
- Becker, Christian M.;
- FinnGen;
- Palotie, Aarno;
- Daly, Mark;
- Riley-Gills, Bridget;
- Jacob, Howard;
- Paul, Dirk;
- Matakidou, Athena;
- Platt, Adam;
- Runz, Heiko;
- John, Sally;
- Okafo, George;
- Lawless, Nathan;
- Salminen-Mankonen, Heli;
- Plenge, Robert;
- Maranville, Joseph
Publication type:
Article
Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata.
Published in:
Nature Communications, 2023, v. 14, p. 1, doi. 10.1038/s41467-023-35974-7
By:
- Sliz, Eeva;
- Tyrmi, Jaakko S.;
- Rahmioglu, Nilufer;
- Zondervan, Krina T.;
- Becker, Christian M.;
- FinnGen;
- Palotie, Aarno;
- Daly, Mark;
- Riley-Gills, Bridget;
- Jacob, Howard;
- Paul, Dirk;
- Matakidou, Athena;
- Platt, Adam;
- Runz, Heiko;
- John, Sally;
- Okafo, George;
- Lawless, Nathan;
- Salminen-Mankonen, Heli;
- Plenge, Robert;
- Maranville, Joseph
Publication type:
Article
Association of Rheumatoid Arthritis Risk Alleles with Response to Anti-TNF Biologics: Results from the CORRONA Registry and Meta-analysis.
Published in:
Inflammation, 2013, v. 36, n. 2, p. 279, doi. 10.1007/s10753-012-9544-4
By:
- Pappas, Dimitrios;
- Oh, Cheongeun;
- Plenge, Robert;
- Kremer, Joel;
- Greenberg, Jeffrey
Publication type:
Article
Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-021-02996-0
By:
- Tamlander, Max;
- Mars, Nina;
- Pirinen, Matti;
- FinnGen;
- Steering Committee;
- Palotie, Aarno;
- Daly, Mark;
- Pharmaceutical companies;
- Riley-Gills, Bridget;
- Jacob, Howard;
- Paul, Dirk;
- Runz, Heiko;
- John, Sally;
- Plenge, Robert;
- Maranville, Joseph;
- Okafo, George;
- Lawless, Nathan;
- Salminen-Mankonen, Heli;
- McCarthy, Mark;
- Hunkapiller, Julie
Publication type:
Article
An N-Ethyl-N-Nitrosourea Mutagenesis Screen for Epigenetic Mutations in the Mouse.
Published in:
Genetics, 2003, v. 164, n. 4, p. 1481, doi. 10.1093/genetics/164.4.1481
By:
- Percec, Ivona;
- Thorvaldsen, Joanne L.;
- Plenge, Robert M.;
- Krapp, Christopher J.;
- Nadeau, Joseph H.;
- Willard, Huntington F.;
- Bartolomei, Marisa S.
Publication type:
Article
Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge.
Published in:
Nature Genetics, 2013, v. 45, n. 5, p. 468, doi. 10.1038/ng.2623
By:
- Plenge, Robert M;
- Greenberg, Jeffrey D;
- Mangravite, Lara M;
- Derry, Jonathan M J;
- Stahl, Eli A;
- Coenen, Marieke J H;
- Barton, Anne;
- Padyukov, Leonid;
- Klareskog, Lars;
- Gregersen, Peter K;
- Mariette, Xavier;
- Moreland, Larry W;
- Bridges, S Louis;
- de Vries, Niek;
- Huizinga, Tom W J;
- Guchelaar, Henk-Jan;
- Friend, Stephen H;
- Stolovitzky, Gustavo
Publication type:
Article
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis.
Published in:
Nature Genetics, 2012, v. 44, n. 5, p. 483, doi. 10.1038/ng.2232
By:
- Stahl, Eli A;
- Wegmann, Daniel;
- Trynka, Gosia;
- Gutierrez-Achury, Javier;
- Do, Ron;
- Voight, Benjamin F;
- Kraft, Peter;
- Chen, Robert;
- Kallberg, Henrik J;
- Kurreeman, Fina A S;
- Kathiresan, Sekar;
- Wijmenga, Cisca;
- Gregersen, Peter K;
- Alfredsson, Lars;
- Siminovitch, Katherine A;
- Worthington, Jane;
- de Bakker, Paul I W;
- Raychaudhuri, Soumya;
- Plenge, Robert M
Publication type:
Article
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis.
Published in:
Nature Genetics, 2012, v. 44, n. 3, p. 291, doi. 10.1038/ng.1076
By:
- Raychaudhuri, Soumya;
- Sandor, Cynthia;
- Stahl, Eli A;
- Freudenberg, Jan;
- Lee, Hye-Soon;
- Jia, Xiaoming;
- Alfredsson, Lars;
- Padyukov, Leonid;
- Klareskog, Lars;
- Worthington, Jane;
- Siminovitch, Katherine A;
- Bae, Sang-Cheol;
- Plenge, Robert M;
- Gregersen, Peter K;
- de Bakker, Paul I W
Publication type:
Article
Unlocking the pathogenesis of celiac disease.
Published in:
Nature Genetics, 2010, v. 42, n. 4, p. 281, doi. 10.1038/ng0410-281
By:
- Plenge, Robert M.
Publication type:
Article
De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot.
Published in:
Nature Genetics, 2009, v. 41, n. 8, p. 931, doi. 10.1038/ng.415
By:
- Greenway, Steven C.;
- Pereira, Alexandre C.;
- Lin, Jennifer C.;
- DePalma, Steven R.;
- Israel, Samuel J.;
- Mesquita, Sonia M.;
- Ergul, Emel;
- Conta, Jessie H.;
- Korn, Joshua M.;
- McCarroll, Steven A.;
- Gorham, Joshua M.;
- Gabriel, Stacey;
- Altshuler, David M.;
- Quintanilla-Dieck, Maria de Lourdes;
- Artunduaga, Maria Alexandra;
- Eavey, Roland D.;
- Plenge, Robert M.;
- Shadick, Nancy A.;
- Weinblatt, Michael E.;
- De Jager, Philip L.
Publication type:
Article
REL, encoding a member of the NF-κB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
Published in:
Nature Genetics, 2009, v. 41, n. 7, p. 820, doi. 10.1038/ng.395
By:
- Gregersen, Peter K.;
- Amos, Chistopher I.;
- Lee, Annette T.;
- Yue Lu;
- Remmers, Elaine F.;
- Kastner, Daniel L.;
- Seldin, Michael F.;
- Criswell, Lindsey A.;
- Plenge, Robert M.;
- Holers, V Michael;
- Mikuls, Ted R.;
- Sokka, Tuulikki.;
- Moreland, Larry W.;
- Bridges, S Louis.;
- Gang Xie;
- Begovich, Ann B.;
- Siminovitch, Katherine A.
Publication type:
Article
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.
Published in:
Nature Genetics, 2008, v. 40, n. 9, p. 1059, doi. 10.1038/ng.200
By:
- Graham, Robert R.;
- Cotsapas, Chris;
- Davies, Leela;
- Hackett, Rachel;
- Lessard, Christopher J.;
- Leon, Joanlise M.;
- Burtt, Noel P.;
- Guiducci, Candace;
- Parkin, Melissa;
- Gates, Casey;
- Plenge, Robert M.;
- Behrens, Timothy W.;
- Wither, Joan E.;
- Rioux, John D.;
- Fortin, Paul R.;
- Graham, Deborah Cunninghame;
- Wong, Andrew K.;
- Vyse, Timothy J.;
- Daly, Mark J.;
- Altshuler, David
Publication type:
Article
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis.
Published in:
Nature Genetics, 2007, v. 39, n. 12, p. 1477, doi. 10.1038/ng.2007.27
By:
- Plenge, Robert M.;
- Cotsapas, Chris;
- Davies, Leela;
- Price, Alkes L.;
- de Bakker, Paul I. W.;
- Maller, Julian;
- Pe'er, Itsik;
- Burtt, Noel P.;
- Blumenstiel, Brendan;
- DeFelice, Matt;
- Parkin, Melissa;
- Barry, Rachel;
- Winslow, Wendy;
- Healy, Claire;
- Graham, Robert R.;
- Neale, Benjamin M.;
- Izmailova, Elena;
- Roubenoff, Ronenn;
- Parker, Alexander N.;
- Glass, Roberta
Publication type:
Article
Principal components analysis corrects for stratification in genome-wide association studies.
Published in:
Nature Genetics, 2006, v. 38, n. 8, p. 904, doi. 10.1038/ng1847
By:
- Price, Alkes L.;
- Patterson, Nick J.;
- Plenge, Robert M.;
- Weinblatt, Michael E.;
- Shadick, Nancy A.;
- Reich, David
Publication type:
Article
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus.
Published in:
Nature Genetics, 2006, v. 38, n. 5, p. 550, doi. 10.1038/ng1782
By:
- Graham, Robert R.;
- Kozyrev, Sergey V.;
- Baechler, Emily C.;
- Reddy, M. V. Prasad Linga;
- Plenge, Robert M.;
- Bauer, Jason W.;
- Ortmann, Ward A.;
- Koeuth, Thearith;
- Escribano, Ma Francisca González;
- Pons-Estel, Bernardo;
- Petri, Michelle;
- Daly, Mark;
- Gregersen, Peter K.;
- Martín, Javier;
- Altshuler, David;
- Behrens, Timothy W.;
- Alarcón-Riquelme, Marta E.
Publication type:
Article
Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia.
Published in:
Nature Genetics, 2006, v. 38, n. 2, p. 214, doi. 10.1038/ng1712
By:
- Bonnen, Penelope E.;
- Pe'er, Itsik;
- Plenge, Robert M.;
- Salit, Jackie;
- Lowe, Jennifer K.;
- Shapero, Michael H.;
- Lifton, Richard P.;
- Breslow, Jan L.;
- Daly, Mark J.;
- Reich, David E.;
- Jones, Keith W.;
- Stoffel, Markus;
- Altshuler, David;
- Friedman, Jeffrey M.
Publication type:
Article
Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140815
By:
- Klarenbeek, Paul L.;
- Doorenspleet, Marieke E.;
- Esveldt, Rebecca E. E.;
- van Schaik, Barbera D. C.;
- Lardy, Neubury;
- van Kampen, Antoine H. C.;
- Tak, Paul P.;
- Plenge, Robert M.;
- Baas, Frank;
- de Bakker, Paul I. W.;
- de Vries, Niek
Publication type:
Article
Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts.
Published in:
PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0136651
By:
- Liao, Katherine P.;
- Ananthakrishnan, Ashwin N.;
- Kumar, Vishesh;
- Xia, Zongqi;
- Cagan, Andrew;
- Gainer, Vivian S.;
- Goryachev, Sergey;
- Chen, Pei;
- Savova, Guergana K.;
- Agniel, Denis;
- Churchill, Susanne;
- Lee, Jaeyoung;
- Murphy, Shawn N.;
- Plenge, Robert M.;
- Szolovits, Peter;
- Kohane, Isaac;
- Shaw, Stanley Y.;
- Karlson, Elizabeth W.;
- Cai, Tianxi
Publication type:
Article
Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098464
By:
- Hutchinson, John N.;
- Raj, Towfique;
- Fagerness, Jes;
- Stahl, Eli;
- Viloria, Fernando T.;
- Gimelbrant, Alexander;
- Seddon, Johanna;
- Daly, Mark;
- Chess, Andrew;
- Plenge, Robert
Publication type:
Article
Modeling Disease Severity in Multiple Sclerosis Using Electronic Health Records.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078927
By:
- Xia, Zongqi;
- Secor, Elizabeth;
- Chibnik, Lori B.;
- Bove, Riley M.;
- Cheng, Suchun;
- Chitnis, Tanuja;
- Cagan, Andrew;
- Gainer, Vivian S.;
- Chen, Pei J.;
- Liao, Katherine P.;
- Shaw, Stanley Y.;
- Ananthakrishnan, Ashwin N.;
- Szolovits, Peter;
- Weiner, Howard L.;
- Karlson, Elizabeth W.;
- Murphy, Shawn N.;
- Savova, Guergana K.;
- Cai, Tianxi;
- Churchill, Susanne E.;
- Plenge, Robert M.
Publication type:
Article
Automatic Prediction of Rheumatoid Arthritis Disease Activity from the Electronic Medical Records.
Published in:
PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0069932
By:
- Lin, Chen;
- Karlson, Elizabeth W.;
- Canhao, Helena;
- Miller, Timothy A.;
- Dligach, Dmitriy;
- Chen, Pei Jun;
- Perez, Raul Natanael Guzman;
- Shen, Yuanyan;
- Weinblatt, Michael E.;
- Shadick, Nancy A.;
- Plenge, Robert M.;
- Savova, Guergana K.
Publication type:
Article
Genetic Risk Score Predicting Risk of Rheumatoid Arthritis Phenotypes and Age of Symptom Onset.
Published in:
PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024380
By:
- Chibnik, Lori B.;
- Keenan, Brendan T.;
- Jing Cui;
- Liao, Katherine P.;
- Costenbader, Karen H.;
- Plenge, Robert M.;
- Karlson, Elizabeth W.
Publication type:
Article
Xenotropic Murine Leukemia Virus-Related Virus Prevalence in Patients with Chronic Fatigue Syndrome or Chronic Immunomodulatory Conditions.
Published in:
Journal of Infectious Diseases, 2010, v. 202, n. 10, p. 1478, doi. 10.1086/657168
By:
- Henrich, Timothy J.;
- Li, Jonathan Z.;
- Felsenstein, Donna;
- Kotton, Camille N.;
- Plenge, Robert M.;
- Pereyra, Florencia;
- Marty, Francisco M.;
- Lin, Nina H.;
- Grazioso, Paul;
- Crochiere, Danielle M.;
- Eggers, Daniel;
- Kuritzkes, Daniel R.;
- Tsibris, Athe M. N.
Publication type:
Article
Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records.
Published in:
Human Genetics, 2014, v. 133, n. 11, p. 1369, doi. 10.1007/s00439-014-1466-9
By:
- Sinnott, Jennifer;
- Dai, Wei;
- Liao, Katherine;
- Shaw, Stanley;
- Ananthakrishnan, Ashwin;
- Gainer, Vivian;
- Karlson, Elizabeth;
- Churchill, Susanne;
- Szolovits, Peter;
- Murphy, Shawn;
- Kohane, Isaac;
- Plenge, Robert;
- Cai, Tianxi
Publication type:
Article
Identifying susceptibility genes for immunological disorders: patterns, power, and proof.
Published in:
Immunological Reviews, 2006, v. 210, n. 1, p. 40, doi. 10.1111/j.0105-2896.2006.00372.x
By:
- Plenge, Robert;
- Rioux, John D.
Publication type:
Article
Portability of an algorithm to identify rheumatoid arthritis in electronic health records.
Published in:
Journal of the American Medical Informatics Association, 2012, v. 19, n. e1, p. e162, doi. 10.1136/amiajnl-2011-000583
By:
- Carroll, Robert J.;
- Thompson, Will K.;
- Eyler, Anne E.;
- Mandelin, Arthur M.;
- Tianxi Cai;
- Zink, Raquel M.;
- Pacheco, Jennifer A.;
- Boomershine, Chad S.;
- Lasko, Thomas A.;
- Hua Xu;
- Karlson, Elizabeth W.;
- Perez, Raul G.;
- Gainer, Vivian S.;
- Murphy, Shawn N.;
- Ruderman, Eric M.;
- Pope, Richard M.;
- Plenge, Robert M.;
- Kho, Abel Ngo;
- Liao, Katherine P.;
- Denny, Joshua C.
Publication type:
Article
Identification and characterization of the human XIST gene promoter: implications for models of X chromosome inactivation.
Published in:
Nucleic Acids Research, 1997, v. 25, n. 13, p. 2661, doi. 10.1093/nar/25.13.2661
By:
- Hendrich, Brian D.;
- Plenge, Robert M.;
- Willard, Huntington F.
Publication type:
Article
Lipid and Lipoprotein Levels and Trend in Rheumatoid Arthritis Compared to the General Population.
Published in:
Arthritis Care & Research, 2013, v. 65, n. 12, p. 2046, doi. 10.1002/acr.22091
By:
- Liao, Katherine P.;
- Cai, Tianxi;
- Gainer, Vivian S.;
- Cagan, Andrew;
- Murphy, Shawn N.;
- Liu, Chihchin;
- Churchill, Susanne;
- Shaw, Stanley Y.;
- Kohane, Isaac;
- Solomon, Daniel H.;
- Plenge, Robert M.;
- Karlson, Elizabeth W.
Publication type:
Article
Using genetic and clinical data to understand response to disease-modifying anti-rheumatic drug therapy: data from the Brigham and Women's Hospital Rheumatoid Arthritis Sequential Study.
Published in:
2011
By:
- Iannaccone, Christine K.;
- Lee, Yvonne C.;
- Cui, Jing;
- Frits, Michelle L.;
- Glass, Roberta J.;
- Plenge, Robert M.;
- Solomon, Daniel H.;
- Weinblatt, Michael E.;
- Shadick, Nancy A.
Publication type:
Journal Article
Using genetic and clinical data to understand response to disease-modifying anti-rheumatic drug therapy: data from the Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study.
Published in:
Rheumatology, 2011, v. 50, n. 1, p. 40, doi. 10.1093/rheumatology/keq263
By:
- Iannaccone, Christine K.;
- Lee, Yvonne C.;
- Cui, Jing;
- Frits, Michelle L.;
- Glass, Roberta J.;
- Plenge, Robert M.;
- Solomon, Daniel H.;
- Weinblatt, Michael E.;
- Shadick, Nancy A.
Publication type:
Article
Disciplined approach to drug discovery and early development.
Published in:
Science Translational Medicine, 2016, v. 8, n. 349, p. 1, doi. 10.1126/scitranslmed.aaf2608
By:
- Plenge, Robert M.
Publication type:
Article
Molecular Underpinnings of Severe Coronavirus Disease 2019.
Published in:
2020
By:
- Plenge, Robert M.
Publication type:
Editorial
TRAF1/C5 locus is associated with response to anti-TNF in rheumatoid arthritis.
Published in:
2012
By:
- Canhão, Helena;
- Rodrigues, Ana;
- Santos, Maria Jose;
- Carmona-Fernandes, Diana;
- Costa, José;
- Santos, Helena;
- Branco, Jaime;
- Plenge, Robert;
- Solomon, Daniel;
- Armas, Jacome;
- Silva, José António;
- Fonseca, João Eurico;
- Karlson, Elizabeth
Publication type:
Abstract
Genome-Wide Association Study of Determinants of Anti-Cyclic Citrullinated Peptide Antibody Titer in Adults with Rheumatoid Arthritis.
Published in:
Molecular Medicine, 2009, v. 15, n. 5/6, p. 136, doi. 10.2119/molmed.2009.00008
By:
- Jing Cui;
- Taylor, Kimberly E.;
- DeStefano, Anita L.;
- Criswell, Lindsey A.;
- Izmailova, Elena S.;
- Parker, Alex;
- Roubenoff, Ronenn;
- Plenge, Robert M.;
- Weinblatt, Michael E.;
- Shadick, Nancy A.;
- Karlson, Elizabeth W.
Publication type:
Article
Genome-Wide Association Scan Identifies Candidate Polymorphisms Associated with Differential Response to Anti-TNF Treatment in Rheumatoid Arthritis.
Published in:
Molecular Medicine, 2008, v. 14, n. 9/10, p. 575, doi. 10.2119/2008-00056.Liu
By:
- Chunyu Liu;
- Batliwalla, Franak;
- Wentian Li;
- Lee, Annette;
- Roubenoff, Ronenn;
- Beckman, Evan;
- Khalili, Houman;
- Damle, Aarti;
- Kern, Marlena;
- Furie, Richard;
- Dupuis, Josée;
- Plenge, Robert M.;
- Coenen, Marieke J. H.;
- Behrens, Timothy W.;
- Carulli, John P.;
- Gregersen, Peter K.
Publication type:
Article
Several Regions in the Major Histocompatibility Complex Confer Risk for Anti-CCP-Antibody Positive Rheumatoid Arthritis, Independent of the DRB1 Locus.
Published in:
Molecular Medicine, 2008, v. 14, n. 5/6, p. 293, doi. 10.2119/2007-00123.Lee
By:
- Lee, Hye-Soon;
- Lee, Annette T.;
- Criswell, Lindsey A.;
- Seldin, Michael F.;
- Amos, Christopher I.;
- Carulli, John P.;
- Navarrete, Cristina;
- Remmers, Elaine F.;
- Kastner, Daniel L.;
- Plenge, Robert M.;
- Li, Wentian;
- Gregersen, Peter K.
Publication type:
Article
Supplement Materials: "Several regions in the major histocompartibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus".
Published in:
Molecular Medicine, 2008, v. 14, n. 5/6, p. 1, doi. 10.2119/2007-00123.Lee
By:
- Lee, Hye-Soon;
- Lee, Annette T.;
- Criswell, Lindsey A.;
- Seldin, Michael F.;
- Amos, Christopher I.;
- Carulli, John P.;
- Navarrete, Cristina;
- Remmers, Elaine F.;
- Kastner, Daniel L.;
- Plenge, Robert M.;
- Wentian Li;
- Gregersen, Peter K.
Publication type:
Article
Expression-based assay of an X-linked gene to examine effects of the X-controlling element (Xce) locus.
Published in:
Mammalian Genome, 2000, v. 11, n. 5, p. 405, doi. 10.1007/s003350010077
By:
- Plenge, Robert M.;
- Percec, Ivona;
- Nadeau, Joseph H.;
- Willard, Huntington F.
Publication type:
Article
A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.
Published in:
Arthritis & Rheumatology, 2017, v. 69, n. 5, p. 976, doi. 10.1002/art.40051
By:
- Saxena, Richa;
- Plenge, Robert M.;
- Bjonnes, Andrew C.;
- Dashti, Hassan S.;
- Okada, Yukinori;
- Gad El Haq, Wessam;
- Hammoudeh, Mohammed;
- Al Emadi, Samar;
- Masri, Basel K.;
- Halabi, Hussein;
- Badsha, Humeira;
- Uthman, Imad W.;
- Margolin, Lauren;
- Gupta, Namrata;
- Mahfoud, Ziyad R.;
- Kapiri, Marianthi;
- Dargham, Soha R.;
- Aranki, Grace;
- Kazkaz, Layla A.;
- Arayssi, Thurayya
Publication type:
Article
HLA-DRB1-Associated Rheumatoid Arthritis Risk at Multiple Levels in African Americans: Hierarchical Classification Systems, Amino Acid Positions, and Residues.
Published in:
Arthritis & Rheumatology, 2014, v. 66, n. 12, p. 3274, doi. 10.1002/art.38855
By:
- Reynolds, Richard J.;
- Ahmed, Altan F.;
- Danila, Maria I.;
- Hughes, Laura B.;
- Gregersen, Peter K.;
- Raychaudhuri, Soumya;
- Plenge, Robert M.;
- Bridges, S. Louis
Publication type:
Article
Data for Genetic Analysis Workshop 16 Problem 1, association analysis of rheumatoid arthritis data.
Published in:
BMC Proceedings, 2009, v. 3, p. 1, doi. 10.1186/1753-6561-3-S7-S2
By:
- Amos, Christopher I.;
- Chen, Wei Vivien;
- Seldin, Michael F.;
- Remmers, Elaine F.;
- Taylor, Kimberly E.;
- Criswell, Lindsey A.;
- Lee, Annette T.;
- Plenge, Robert M.;
- Kastner, Daniel L.;
- Gregersen, Peter K.
Publication type:
Article
Rheumatoid arthritis genetics: 2009 update.
Published in:
Current Rheumatology Reports, 2009, v. 11, n. 5, p. 351, doi. 10.1007/s11926-009-0050-0
By:
- Plenge, Robert
Publication type:
Article
Quantifying Missing Heritability at Known GWAS Loci.
Published in:
PLoS Genetics, 2013, v. 9, n. 12, p. 1, doi. 10.1371/journal.pgen.1003993
By:
- Gusev, Alexander;
- Bhatia, Gaurav;
- Zaitlen, Noah;
- Vilhjalmsson, Bjarni J.;
- Diogo, Dorothée;
- Stahl, Eli A.;
- Gregersen, Peter K.;
- Worthington, Jane;
- Klareskog, Lars;
- Raychaudhuri, Soumya;
- Plenge, Robert M.;
- Pasaniuc, Bogdan;
- Price, Alkes L.
Publication type:
Article
Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions.
Published in:
PLoS Genetics, 2009, v. 5, n. 6, p. 1, doi. 10.1371/journal.pgen.1000534
By:
- Raychaudhuri, Soumya;
- Plenge, Robert M.;
- Rossin, Elizabeth J.;
- Ng, Aylwin C. Y.;
- Purcell, Shaun M.;
- Sklar, Pamela;
- Scolnick, Edward M.;
- Xavier, Ramnik J.;
- Altshuler, David;
- Daly, Mark J.
Publication type:
Article
Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines.
Published in:
PLoS Genetics, 2008, v. 4, n. 11, p. 1, doi. 10.1371/journal.pgen.1000287
By:
- Choy, Edwin;
- Yelensky, Roman;
- Bonakdar, Sasha;
- Plenge, Robert M.;
- Saxena, Richa;
- De Jager, Philip L.;
- Shaw, Stanley Y.;
- Wolfish, Cara S.;
- Slavik, Jacqueline M.;
- Cotsapas, Chris;
- Rivas, Manuel;
- Dermitzakis, Emmanouil T.;
- Cahir-McFarland, Ellen;
- Kieff, Elliott;
- Hafler, David;
- Daly, Mark J.;
- Altshuler, David
Publication type:
Article
Specificity of the STAT4 Genetic Association for Severe Disease Manifestations of Systemic Lupus Erythematosus.
Published in:
PLoS Genetics, 2008, v. 4, n. 5, p. 1, doi. 10.1371/journal.pgen.1000084
By:
- Taylor, Kimberly E.;
- Remmers, Elaine F.;
- Lee, Annette T.;
- Ortmann, Ward A.;
- Plenge, Robert M.;
- Chao Tian;
- Chung, Sharon A.;
- Nititham, Joanne;
- Hom, Geoffrey;
- Kao, Amy H.;
- Demirci, F. Yesim;
- Kamboh, M. Ilyas;
- Petri, Michelle;
- Manzi, Susan;
- Kastner, Daniel L.;
- Seldin, Michael F.;
- Gregersen, Peter K.;
- Behrens, Timothy W.;
- Criswell, Lindsey A.
Publication type:
Article
Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis.
Published in:
PLoS Genetics, 2008, v. 4, n. 4, p. 1, doi. 10.1371/journal.pgen.1000024
By:
- Fernando, Michelle M. A.;
- Stevens, Christine R.;
- Walsh, Emily C.;
- De Jager, Philip L.;
- Goyette, Philippe;
- Plenge, Robert M.;
- Vyse, Timothy J.;
- Rioux, John D.
Publication type:
Article
Analysis and Application of European Genetic Substructure Using 300 K SNP Information.
Published in:
PLoS Genetics, 2008, v. 4, n. 1, p. e4, doi. 10.1371/journal.pgen.0040004
By:
- Chao Tian;
- Plenge, Robert M.;
- Ransom, Michael;
- Lee, Annette;
- Villoslada, Pablo;
- Selmi, Carlo;
- Klareskog, Lars;
- Pulver, Ann E.;
- Lihong Qi;
- Gregersen, Peter K.;
- Seldin, Michael F.
Publication type:
Article
Genomic Technology Applied to Pharmacological Traits.
Published in:
2011
By:
- Jun J. Yang;
- Plenge, Robert M.
Publication type:
Opinion

Found: 56