Works matching AU Piomelli, Daniele

Results: 137

Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis.

Published in:

Angewandte Chemie, 2016, v. 128, n. 37, p. 11359, doi. 10.1002/ange.201603746

By:

Migliore, Marco;
Pontis, Silvia;
Fuentes de Arriba, Angel Luis;
Realini, Natalia;
Torrente, Esther;
Armirotti, Andrea;
Romeo, Elisa;
Di Martino, Simona;
Russo, Debora;
Pizzirani, Daniela;
Summa, Maria;
Lanfranco, Massimiliano;
Ottonello, Giuliana;
Busquet, Perrine;
Jung, Kwang ‐ Mook;
Garcia ‐ Guzman, Miguel;
Heim, Roger;
Scarpelli, Rita;
Piomelli, Daniele

Publication type:

Article

Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase.

Published in:

Angewandte Chemie, 2015, v. 127, n. 2, p. 495, doi. 10.1002/ange.201409042

By:

Pizzirani, Daniela;
Bach, Anders;
Realini, Natalia;
Armirotti, Andrea;
Mengatto, Luisa;
Bauer, Inga;
Girotto, Stefania;
Pagliuca, Chiara;
De Vivo, Marco;
Summa, Maria;
Ribeiro, Alison;
Piomelli, Daniele

Publication type:

Article

Innentitelbild: Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase (Angew. Chem. 2/2015).

Published in:

Angewandte Chemie, 2015, v. 127, n. 2, p. 374, doi. 10.1002/ange.201410931

By:

Pizzirani, Daniela;
Bach, Anders;
Realini, Natalia;
Armirotti, Andrea;
Mengatto, Luisa;
Bauer, Inga;
Girotto, Stefania;
Pagliuca, Chiara;
De Vivo, Marco;
Summa, Maria;
Ribeiro, Alison;
Piomelli, Daniele

Publication type:

Article

Serum Endocannabinoid Levels in Patients With End-Stage Renal Disease.

Published in:

Journal of the Endocrine Society, 2019, v. 3, n. 10, p. 1869, doi. 10.1210/js.2019-00242

By:

Moradi, Hamid;
Park, Christina;
Igarashi, Miki;
Streja, Elani;
Argueta, Donovan A;
Soohoo, Melissa;
Daglian, Jennifer;
You, Amy S;
Rhee, Connie M;
Kashyap, Moti L;
DiPatrizio, Nicholas V;
Vaziri, Nosratola D;
Kalantar-Zadeh, Kamyar;
Piomelli, Daniele

Publication type:

Article

Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid.

Published in:

Journal of Neural Transmission, 2009, v. 116, n. 3, p. 301, doi. 10.1007/s00702-008-0169-6

By:

Koethe, Dagmar;
Schreiber, Daniela;
Giuffrida, Andrea;
Mauss, Christian;
Faulhaber, Johannes;
Heydenreich, Bernd;
Hellmich, Martin;
Graf, Rudolf;
Klosterkötter, Joachim;
Piomelli, Daniele;
Leweke, F. Markus

Publication type:

Article

The case for medical marijuana.

Published in:

2009

By:

Piomelli, Daniele

Publication type:

Book Review

Bedside to Bench: The element of surprise.

Published in:

Nature Medicine, 2008, v. 14, n. 7, p. 720, doi. 10.1038/nm0708-720

By:

Piomelli, Daniele

Publication type:

Article

THC: moderation during implantation.

Published in:

Nature Medicine, 2004, v. 10, n. 1, p. 19, doi. 10.1038/nm0104-19

By:

Piomelli, Daniele

Publication type:

Article

Modulation of anxiety through blockade of anandamide hydrolysis.

Published in:

Nature Medicine, 2003, v. 9, n. 1, p. 76, doi. 10.1038/nm803

By:

Kathuria, Satish;
Gaetani, Silvana;
Fegley, Darren;
Valiño, Fernando;
Duranti, Andrea;
Tontini, Andrea;
Mor, Marco;
Tarzia, Giorgio;
Rana, Giovanna La;
Calignano, Antonio;
Giustino, Arcangela;
Tattoli, Maria;
Palmery, Maura;
Cuomo, Vincenzo;
Piomelli, Daniele

Publication type:

Article

Cannabinoid activity curtails cocaine craving.

Published in:

Nature Medicine, 2001, v. 7, n. 10, p. 1099, doi. 10.1038/nm1001-1099

By:

Piomelli, Daniele

Publication type:

Article

Pot of gold for glioma therapy.

Published in:

Nature Medicine, 2000, v. 6, n. 3, p. 255, doi. 10.1038/73088

By:

Piomelli, Daniele

Publication type:

Article

P007. Inhibition of monoacylglycerol lipase activity modulates the activation of brain structures relevant for migraine pathogenesis.

Published in:

Journal of Headache & Pain, 2015, v. 16, p. 1, doi. 10.1186/1129-2377-16-S1-A165

By:

Greco, Rosaria;
Bandiera, Tiziano;
Mangione, Antonina S.;
Demartini, Chiara;
Nappi, Giuseppe;
Sandrini, Giorgio;
Piomelli, Daniele;
Tassorelli, Cristina

Publication type:

Article

Diet-Induced Obesity Disrupts Histamine-Dependent Oleoylethanolamide Signaling in the Mouse Liver.

Published in:

Pharmacology, 2022, v. 107, n. 7/8, p. 423, doi. 10.1159/000524753

By:

Lin, Lin;
Mabou Tagne, Alex;
Squire, Erica N.;
Lee, Hye-Lim;
Fotio, Yannick;
Ramirez, Jade;
Zheng, Mimi;
Torrens, Alexa;
Ahmed, Faizy;
Ramos, Raul;
Plikus, Maksim V.;
Piomelli, Daniele

Publication type:

Article

Publisher Correction: Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin.

Published in:

2021

By:

Lai, Michele;
Amato, Rachele;
La Rocca, Veronica;
Bilgin, Mesut;
Freer, Giulia;
Spezia, Piergiorgio;
Quaranta, Paola;
Piomelli, Daniele;
Pistello, Mauro

Publication type:

Correction Notice

Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0135113

By:

Yu, Tian;
Taussig, Matthew D.;
DiPatrizio, Nicholas V.;
Astarita, Giuseppe;
Piomelli, Daniele;
Bergman, Bryan C.;
Dell’Acqua, Mark L.;
Eckel, Robert H.;
Wang, Hong

Publication type:

Article

Methamphetamine Accelerates Cellular Senescence through Stimulation of De Novo Ceramide Biosynthesis.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0116961

By:

Astarita, Giuseppe;
Avanesian, Agnesa;
Grimaldi, Benedetto;
Realini, Natalia;
Justinova, Zuzana;
Panlilio, Leight V.;
Basit, Abdul;
Goldberg, Steven R.;
Piomelli, Daniele

Publication type:

Article

Brown Adipose Tissue Quantification in Human Neonates Using Water-Fat Separated MRI.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077907

By:

Rasmussen, Jerod M.;
Entringer, Sonja;
Nguyen, Annie;
van Erp, Theo G. M.;
Guijarro, Ana;
Oveisi, Fariba;
Swanson, James M.;
Piomelli, Daniele;
Wadhwa, Pathik D.;
Buss, Claudia;
Potkin, Steven G.

Publication type:

Article

Pharmacological Characterization of Memoquin, a Multi-Target Compound for the Treatment of Alzheimer's Disease.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056870

By:

Capurro, Valeria;
Busquet, Perrine;
Lopes, Joao Pedro;
Bertorelli, Rosalia;
Tarozzo, Glauco;
Bolognesi, Maria Laura;
Piomelli, Daniele;
Reggiani, Angelo;
Cavalli, Andrea

Publication type:

Article

Associations of Fatty Acids in Cerebrospinal Fluid with Peripheral Glucose Concentrations and Energy Metabolism.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041503

By:

Jumpertz, Reiner;
Guijarro, Ana;
Pratley, Richard E;
Mason, Clinton C.;
Piomelli, Daniele;
Krakoff, Jonathan

Publication type:

Article

A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0032397

By:

Lodola, Alessio;
Branduardi, Davide;
De Vivo, Marco;
Capoferri, Luigi;
Mor, Marco;
Piomelli, Daniele;
Cavalli, Andrea

Publication type:

Article

Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0028142

By:

Cippitelli, Andrea;
Astarita, Giuseppe;
Duranti, Andrea;
Caprioli, Giovanni;
Ubaldi, Massimo;
Stopponi, Serena;
Kallupi, Marsida;
Sagratini, Gianni;
de Fonseca, Fernando Rodrìguez;
Piomelli, Daniele;
Ciccocioppo, Roberto

Publication type:

Article

Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0024777

By:

Astarita, Giuseppe;
Jung, Kwang-Mook;
Vasilevko, Vitaly;
DiPatrizio, Nicholas V.;
Martin, Sarah K.;
Cribbs, David H.;
Head, Elizabeth;
Cotman, Carl W.;
Piomelli, Daniele

Publication type:

Article

Dietary and Behavioral Interventions Protect against Age Related Activation of Caspase Cascades in the Canine Brain.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024652

By:

Snigdha, Shikha;
Berchtold, Nicole;
Astarita, Giuseppe;
Saing, Tommy;
Piomelli, Daniele;
Cotman, Carl W.

Publication type:

Article

Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease.

Published in:

PLoS ONE, 2010, v. 5, n. 9, p. 1, doi. 10.1371/journal.pone.0012538

By:

Astarita, Giuseppe;
Jung, Kwang-Mook;
Berchtold, Nicole C.;
Nguyen, Vinh Q.;
Gillen, Daniel L.;
Head, Elizabeth;
Cotman, Carl W.;
Piomelli, Daniele

Publication type:

Article

Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010891

By:

Alkaitis, Matthew S.;
Solorzano, Carlos;
Landry, Russell P.;
Piomelli, Daniele;
DeLeo, Joyce A.;
Romero-Sandoval, E. Alfonso

Publication type:

Article

Multitarget fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti-inflammatory drug-dependent gastrointestinal damage.

Published in:

FASEB Journal, 2015, v. 29, n. 6, p. 2616, doi. 10.1096/fj.15-270637

By:

Sasso, Oscar;
Migliore, Marco;
Habrant, Damien;
Armirotti, Andrea;
Albani, Clara;
Summa, Maria;
Moreno-Sanz, Guillermo;
Scarpelli, Rita;
Piomelli, Daniele

Publication type:

Article

The FAAH inhibitor PF‐04457845 has THC‐like rewarding and reinstatement effects in squirrel monkeys and increases dopamine levels in the nucleus accumbens shell in rats (838.6).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.838.6

By:

Justinova, Zuzana;
Mascia, Paola;
Secci, Maria;
Redhi, Godfrey;
Piomelli, Daniele;
Goldberg, Steven

Publication type:

Article

Endocannabinoid signaling in the gut mediates preference for dietary unsaturated fats.

Published in:

FASEB Journal, 2013, v. 27, n. 6, p. 2513, doi. 10.1096/fj.13-227587

By:

DiPatrizio, Nicholas V.;
Joslin, Alexandra;
Kwang-Mook Jung;
Piomelli, Daniele

Publication type:

Article

Lack of abuse liability of the FAAH inhibitor URB597 in squirrel monkeys.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A409, doi. 10.1096/fasebj.21.5.a409-c

By:

Justinova, Zuzana;
Bortolato, Marco;
Mangieri, Regina;
Mukhin, Alex G.;
Chefer, Svetlana I.;
Piomelli, Daniele;
Goldberg, Steven R.

Publication type:

Article

Enhancement of peripheral fatty acyl ethanolamide signaling prevents stress-induced social avoidance and anxiety-like behaviors in male rats.

Published in:

Psychopharmacology, 2025, v. 242, n. 5, p. 997, doi. 10.1007/s00213-023-06473-w

By:

Carnevali, Luca;
Barbetti, Margherita;
Fotio, Yannick;
Ferlenghi, Francesca;
Vacondio, Federica;
Mor, Marco;
Piomelli, Daniele;
Sgoifo, Andrea

Publication type:

Article

N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats.

Published in:

Psychopharmacology, 2021, v. 238, n. 1, p. 249, doi. 10.1007/s00213-020-05678-7

By:

Fotio, Yannick;
Ciccocioppo, Roberto;
Piomelli, Daniele

Publication type:

Article

Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety.

Published in:

Psychopharmacology, 2018, v. 235, n. 11, p. 3211, doi. 10.1007/s00213-018-5020-7

By:

Danandeh, Andalib;
Vozella, Valentina;
Lim, James;
Oveisi, Fariba;
Ramirez, Gina L.;
Mears, David;
Wynn, Gary;
Piomelli, Daniele

Publication type:

Article

Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats.

Published in:

Psychopharmacology, 2016, v. 233, n. 10, p. 1879, doi. 10.1007/s00213-015-4140-6

By:

Panlilio, Leigh;
Thorndike, Eric;
Nikas, Spyros;
Alapafuja, Shakiru;
Bandiera, Tiziano;
Cravatt, Benjamin;
Makriyannis, Alexandros;
Piomelli, Daniele;
Goldberg, Steven;
Justinova, Zuzana

Publication type:

Article

A role for the endocannabinoid 2-arachidonoyl- sn-glycerol for social and high-fat food reward in male mice.

Published in:

Psychopharmacology, 2016, v. 233, n. 10, p. 1911, doi. 10.1007/s00213-016-4222-0

By:

Wei, Don;
Lee, DaYeon;
Li, Dandan;
Daglian, Jennifer;
Jung, Kwang-Mook;
Piomelli, Daniele

Publication type:

Article

Inhibition of fatty acid amide hydrolase in the CNS prevents and reverses morphine tolerance in male and female mice.

Published in:

2020

By:

Fotio, Yannick;
Palese, Francesca;
Guaman Tipan, Pablo;
Ahmed, Faizy;
Piomelli, Daniele

Publication type:

journal article

Suppression of acute and anticipatory nausea by peripherally restricted fatty acid amide hydrolase inhibitor in animal models: role of PPARα and CB<sub>1</sub> receptors.

Published in:

2017

By:

Rock, Erin M;
MorENo ‐ Sanz, Guillermo;
Limebeer, Cheryl L;
Petrie, Gavin N;
Angelini, Roberto;
Piomelli, Daniele;
Parker, Linda A;
Moreno-Sanz, Guillermo

Publication type:

journal article

Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain.

Published in:

2011

By:

Guindon, Josée;
Guijarro, Ana;
Piomelli, Daniele;
Hohmann, Andrea G.;
Guindon, Josée

Publication type:

journal article

Ceramide contributes to pathogenesis and may be targeted for therapy in VCP inclusion body myopathy.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 24, p. 3945, doi. 10.1093/hmg/ddaa248

By:

Weiss, Lan;
Jung, Kwang-Mook;
Nalbandian, Angele;
Llewellyn, Katrina;
Yu, Howard;
Ta, Lac;
Chang, Isabela;
Migliore, Marco;
Squire, Erica;
Ahmed, Faizy;
Piomelli, Daniele;
Kimonis, Virginia

Publication type:

Article

Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 5, p. 1333, doi. 10.1093/hmg/ddt523

By:

Llewellyn, Katrina J.;
Nalbandian, Angèle;
Jung, Kwang-Mook;
Nguyen, Christopher;
Avanesian, Agnesa;
Mozaffar, Tahseen;
Piomelli, Daniele;
Kimonis, Virginia E.

Publication type:

Article

Impact of Circulating N-Acylethanolamine Levels with Clinical and Laboratory End Points in Hemodialysis Patients.

Published in:

2021

By:

Pai, Alex Y.;
Wenziger, Cachet;
Streja, Elani;
Argueta, Donovan A.;
DiPatrizio, Nicholas V.;
Rhee, Connie M.;
Vaziri, Nosratola D.;
Kalantar-Zadeh, Kamyar;
Piomelli, Daniele;
Moradi, Hamid

Publication type:

journal article

Circulating Endocannabinoids and Mortality in Hemodialysis Patients.

Published in:

2020

By:

Moradi, Hamid;
Park, Christina;
Streja, Elani;
Argueta, Donovan A.;
DiPatrizio, Nicholas V.;
You, Amy S.;
Rhee, Connie M.;
Vaziri, Nosratola D.;
Kalantar-Zadeh, Kamyar;
Piomelli, Daniele;
Argueta, Donovan A;
DiPatrizio, Nicholas V;
You, Amy S;
Rhee, Connie M;
Vaziri, Nosratola D

Publication type:

journal article

Familial abnormalities of endocannabinoid signaling in schizophrenia.

Published in:

World Journal of Biological Psychiatry, 2019, v. 20, n. 2, p. 117, doi. 10.1080/15622975.2018.1449966

By:

Koethe, Dagmar;
Pahlisch, Franziska;
Hellmich, Martin;
Rohleder, Cathrin;
Mueller, Juliane K.;
Meyer-Lindenberg, Andreas;
Torrey, E. Fuller;
Piomelli, Daniele;
Leweke, F. Markus

Publication type:

Article

A Lipid Gate for the Peripheral Control of Pain.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 46, p. 15184, doi. 10.1523/JNEUROSCI.3475-14.2014

By:

Piomelli, Daniele;
Hohmann, Andrea G.;
Seybold, Virginia;
Hammock, Bruce D.

Publication type:

Article

Peroxisome Proliferator-Activated Receptor a Mediates Acute Effects of Palmitoylethanolamide on Sensory Neurons.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 37, p. 12735, doi. 10.1523/JNEUROSCI.0130-12.2012

By:

Khasabova, Iryna A.;
Yee Xiong;
Coicou, Lia G.;
Piomelli, Daniele;
Seybold, Virginia

Publication type:

Article

Activation of Type 5 Metabotropic Glutamate Receptors and Diacylglycerol Lipase-&agr; Initiates 2-Arachidonoylglycerol Formation and Endocannabinoid-Mediated Analgesia.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 28, p. 9457, doi. 10.1523/JNEUROSCI.0013-12.2012

By:

Gregg, Laura C.;
Jung, Kwang-Mook;
Spradley, Jessica M.;
Nyilas, Rita;
Suplita II, Richard L.;
Zimmer, Andreas;
Watanabe, Masahiko;
Mackie, Ken;
Katona, István;
Piomelli, Daniele;
Hohmann, Andrea G.

Publication type:

Article

Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1410, doi. 10.1080/14756366.2021.1912035

By:

Ghidini, Andrea;
Scalvini, Laura;
Palese, Francesca;
Lodola, Alessio;
Mor, Marco;
Piomelli, Daniele

Publication type:

Article

Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL.

Published in:

Scientific Reports, 2016, p. 31046, doi. 10.1038/srep31046

By:

Scalvini, Laura;
Vacondio, Federica;
Bassi, Michele;
Pala, Daniele;
Lodola, Alessio;
Rivara, Silvia;
Jung, Kwang-Mook;
Piomelli, Daniele;
Mor, Marco

Publication type:

Article

Erratum: Peripheral gating of pain signals by endogenous lipid mediators.

Published in:

Nature Neuroscience, 2014, v. 17, n. 9, p. 1287, doi. 10.1038/nn0914-1287d

By:

Piomelli, Daniele;
Sasso, Oscar

Publication type:

Article

Peripheral gating of pain signals by endogenous lipid mediators.

Published in:

Nature Neuroscience, 2014, v. 17, n. 2, p. 164, doi. 10.1038/nn.3612

By:

Piomelli, Daniele;
Sasso, Oscar

Publication type:

Article

Corrigendum: A catalytically silent FAAH-1 variant drives anandamide transport in neurons.

Published in:

Nature Neuroscience, 2013, v. 16, n. 12, p. 1907, doi. 10.1038/nn1213-1907a

By:

Fu, Jin;
Bottegoni, Giovanni;
Sasso, Oscar;
Bertorelli, Rosalia;
Rocchia, Walter;
Masetti, Matteo;
Guijarro, Ana;
Lodola, Alessio;
Armirotti, Andrea;
Garau, Gianpiero;
Bandiera, Tiziano;
Reggiani, Angelo;
Mor, Marco;
Cavalli, Andrea;
Piomelli, Daniele

Publication type:

Article