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Lactobacillus rhamnosus GG increases cyclooxygenase‐2 expression and prostaglandin E2 secretion in colonic myofibroblasts via a MyD88‐dependent mechanism during homeostasis.
Published in:
Cellular Microbiology, 2018, v. 20, n. 11, p. N.PAG, doi. 10.1111/cmi.12871
By:
- Uribe, Gabriela;
- Villéger, Romain;
- Bressollier, Philippe;
- Dillard, Rachel N.;
- Worthley, Daniel L.;
- Wang, Timothy C.;
- Powell, Don W.;
- Urdaci, Maria C.;
- Pinchuk, Irina V.
Publication type:
Article
Role of PD-L1 in Gut Mucosa Tolerance and Chronic Inflammation.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 23, p. 9165, doi. 10.3390/ijms21239165
By:
- Chulkina, Marina;
- Beswick, Ellen J.;
- Pinchuk, Irina V.
Publication type:
Article
Expression of Programmed Death-Ligand 1 by Human Colonic CD90+ Stromal Cells Differs Between Ulcerative Colitis and Cohn's Disease and Determines Their Capacity to Suppress Th1 Cells.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01125
By:
- Beswick, Ellen J.;
- Grim, Carl;
- Singh, Abinav;
- Aguirre, Jose E.;
- Tafoya, Marissa;
- Suimin Qiu;
- Rogler, Gerhard;
- McKee, Rohini;
- Samedi, Von;
- Ma, Thomas Y.;
- Reyes, Victor E.;
- Powell, Don W.;
- Pinchuk, Irina V.;
- Bemark, Mats;
- Bimczok, Diane;
- Griffin, Matthew
Publication type:
Article
Helicobacter pylori cag Pathogenicity Island's Role in B7-H1 Induction and Immune Evasion.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121841
By:
- Lina, Taslima T.;
- Alzahrani, Shatha;
- House, Jennifer;
- Yamaoka, Yoshio;
- Sharpe, Arlene H.;
- Rampy, Bill A.;
- Pinchuk, Irina V.;
- Reyes, Victor E.
Publication type:
Article
Chronic Macrophage Migration Inhibitory Factor Exposure Induces Mesenchymal Epithelial Transition and Promotes Gastric and Colon Cancers.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098656
By:
- Morris, Katherine T.;
- Nofchissey, Robert A.;
- Pinchuk, Irina V.;
- Beswick, Ellen J.
Publication type:
Article
Stromal Cells Induce Th17 during Helicobacter pylori Infection and in the Gastric Tumor Microenvironment.
Published in:
PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053798
By:
- Pinchuk, Irina V.;
- Morris, Katherine T.;
- Nofchissey, Robert A.;
- Earley, Rachel B.;
- Jeng-Yih Wu;
- Ma, Thomas Y.;
- Beswick, Ellen J.
Publication type:
Article
BRD4‐MK2 signaling: target for Crohn's Disease‐associated fibrosis.
Published in:
FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R5801
By:
- Chulkina, Marina;
- McAninch, Steven;
- Li, Yi;
- Koltun, Walter;
- Yochum, Gregory;
- Tian, Bing;
- Zhou, Jia;
- Beswick, Ellen J.;
- Brasier, Allan R.;
- Pinchuk, Irina V.
Publication type:
Article
Cystathionine Gamma-Lyase Regulates TNF-α-Mediated Injury Response in Human Colonic Epithelial Cells and Colonoids.
Published in:
Antioxidants, 2024, v. 13, n. 9, p. 1067, doi. 10.3390/antiox13091067
By:
- Arroyo Almenas, Francisco;
- Törő, Gábor;
- Szaniszlo, Peter;
- Maskey, Manjit;
- Thanki, Ketan K.;
- Koltun, Walter A.;
- Yochum, Gregory S.;
- Pinchuk, Irina V.;
- Chao, Celia;
- Hellmich, Mark R.;
- Módis, Katalin
Publication type:
Article
CD90+ stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer.
Published in:
International Journal of Cancer, 2016, v. 138, n. 8, p. 1971, doi. 10.1002/ijc.29939
By:
- Huynh, Phuong T.;
- Beswick, Ellen J.;
- Coronado, Yun A.;
- Johnson, Paul;
- O'Connell, Malaney R.;
- Watts, Tammara;
- Singh, Pomila;
- Qiu, Suimin;
- Morris, Katherine;
- Powell, Don W.;
- Pinchuk, Irina V.
Publication type:
Article
Blockade of MK2 is protective in inflammation-associated colorectal cancer development.
Published in:
International Journal of Cancer, 2016, v. 138, n. 3, p. 770, doi. 10.1002/ijc.29716
By:
- Ray, Anita L.;
- Castillo, Eliseo F.;
- Morris, Katherine T.;
- Nofchissey, Robert A.;
- Weston, Lea L.;
- Samedi, Von G.;
- Hanson, Joshua A.;
- Gaestel, Matthias;
- Pinchuk, Irina V.;
- Beswick, Ellen J.
Publication type:
Article
Cytokine release syndrome in COVID‐19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex.
Published in:
Journal of Leukocyte Biology, 2021, v. 109, n. 1, p. 55, doi. 10.1002/JLB.3COVA0820-410RRR
By:
- Petrey, Aaron C.;
- Qeadan, Fares;
- Middleton, Elizabeth A.;
- Pinchuk, Irina V.;
- Campbell, Robert A.;
- Beswick, Ellen J.
Publication type:
Article
Loss of alcohol dehydrogenase 1B in cancer-associated fibroblasts: contribution to the increase of tumor-promoting IL-6 in colon cancer.
Published in:
British Journal of Cancer, 2023, v. 128, n. 4, p. 537, doi. 10.1038/s41416-022-02066-0
By:
- Villéger, Romain;
- Chulkina, Marina;
- Mifflin, Randy C.;
- Markov, Nikolay S.;
- Trieu, Judy;
- Sinha, Mala;
- Johnson, Paul;
- Saada, Jamal I.;
- Adegboyega, Patrick A.;
- Luxon, Bruce A.;
- Beswick, Ellen J.;
- Powell, Don W.;
- Pinchuk, Irina V.
Publication type:
Article
PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment.
Published in:
Journal of Translational Medicine, 2016, v. 14, p. 1, doi. 10.1186/s12967-016-1091-6
By:
- Watts, Tammara L.;
- Cui, Ruwen;
- Szaniszlo, Peter;
- Resto, Vicente A.;
- Powell, Don W.;
- Pinchuk, Irina V.
Publication type:
Article
Drug–Microbiota Interaction in Colon Cancer Therapy: Impact of Antibiotics.
Published in:
Biomedicines, 2021, v. 9, n. 3, p. 259, doi. 10.3390/biomedicines9030259
By:
- Mohamed, Ali;
- Menon, Harry;
- Chulkina, Marina;
- Yee, Nelson S.;
- Pinchuk, Irina V.;
- Niikura, Ryota
Publication type:
Article
Inflammation, Immunity, and Vaccines for Helicobacter pylori Infection.
Published in:
Helicobacter, 2012, p. 16, doi. 10.1111/j.1523-5378.2012.00977.x
By:
- Ihan, Alojz;
- Pinchuk, Irina V.;
- Beswick, Ellen J.
Publication type:
Article
Matrix metalloproteinases cleave membrane-bound PD-L1 on CD90+ (myo-)fibroblasts in Crohn's disease and regulate Th1/Th17 cell responses.
Published in:
International Immunology, 2020, v. 32, n. 1, p. 57, doi. 10.1093/intimm/dxz060
By:
- Aguirre, Jose E;
- Beswick, Ellen J;
- Grim, Carl;
- Uribe, Gabriela;
- Tafoya, Marissa;
- Palma, Gabriela Chacon;
- Samedi, Von;
- McKee, Rohini;
- Villeger, Romain;
- Fofanov, Yuriy;
- Cong, Yingzi;
- Yochum, Gregory;
- Koltun, Walter;
- Powell, Don;
- Pinchuk, Irina V
Publication type:
Article
Increased Activity of MAPKAPK2 within Mesenchymal Cells as a Target for Inflammation-Associated Fibrosis in Crohn's Disease.
Published in:
Journal of Crohn's & Colitis, 2024, v. 18, n. 7, p. 1147, doi. 10.1093/ecco-jcc/jjae009
By:
- Chulkina, Marina;
- Rohmer, Christina;
- McAninch, Steven;
- Panganiban, Ronaldo P;
- Villéger, Romain;
- Portolese, Austin;
- Ciocirlan, Justin;
- Yang, Wenjing;
- Cohen, Claire;
- Koltun, Walter;
- Valentine, John F;
- Cong, Yingzi;
- Yochum, Gregory;
- Beswick, Ellen J;
- Pinchuk, Irina V
Publication type:
Article
Impairment of Tissue-Resident Mesenchymal Stem Cells in Chronic Ulcerative Colitis and Crohn's Disease.
Published in:
Journal of Crohn's & Colitis, 2021, v. 15, n. 8, p. 1362, doi. 10.1093/ecco-jcc/jjab001
By:
- Grim, Carl;
- Noble, Robert;
- Uribe, Gabriela;
- Khanipov, Kamil;
- Johnson, Paul;
- Koltun, Walter A;
- Watts, Tammara;
- Fofanov, Yuriy;
- Yochum, Gregory S;
- Powell, Don W;
- Beswick, Ellen J;
- Pinchuk, Irina V
Publication type:
Article
Activation PDGFR-α/AKT Mediated Signaling Pathways in Oral Squamous Cell Carcinoma by Mesenchymal Stem/Stromal Cells Promotes Anti-apoptosis and Decreased Sensitivity to Cisplatin.
Published in:
Frontiers in Oncology, 2020, v. 10, p. 1, doi. 10.3389/fonc.2020.00552
By:
- Wang, Jia;
- Cui, Ruwen;
- Clement, Cecila G.;
- Nawgiri, Ranjana;
- Powell, Don W.;
- Pinchuk, Irina V.;
- Watts, Tammara L.
Publication type:
Article

Found: 19

Lactobacillus rhamnosus GG increases cyclooxygenase‐2 expression and prostaglandin E2 secretion in colonic myofibroblasts via a MyD88‐dependent mechanism during homeostasis.

Role of PD-L1 in Gut Mucosa Tolerance and Chronic Inflammation.

Expression of Programmed Death-Ligand 1 by Human Colonic CD90<sup>+</sup> Stromal Cells Differs Between Ulcerative Colitis and Cohn's Disease and Determines Their Capacity to Suppress Th1 Cells.

Helicobacter pylori cag Pathogenicity Island's Role in B7-H1 Induction and Immune Evasion.

Chronic Macrophage Migration Inhibitory Factor Exposure Induces Mesenchymal Epithelial Transition and Promotes Gastric and Colon Cancers.

Stromal Cells Induce Th17 during Helicobacter pylori Infection and in the Gastric Tumor Microenvironment.

BRD4‐MK2 signaling: target for Crohn's Disease‐associated fibrosis.

Cystathionine Gamma-Lyase Regulates TNF-α-Mediated Injury Response in Human Colonic Epithelial Cells and Colonoids.

CD90<sup>+</sup> stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer.

Blockade of MK2 is protective in inflammation-associated colorectal cancer development.

Cytokine release syndrome in COVID‐19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex.

Loss of alcohol dehydrogenase 1B in cancer-associated fibroblasts: contribution to the increase of tumor-promoting IL-6 in colon cancer.

PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment.

Drug–Microbiota Interaction in Colon Cancer Therapy: Impact of Antibiotics.

Inflammation, Immunity, and Vaccines for Helicobacter pylori Infection.

Matrix metalloproteinases cleave membrane-bound PD-L1 on CD90<sup>+</sup> (myo-)fibroblasts in Crohn's disease and regulate T<sub>h</sub>1/T<sub>h</sub>17 cell responses.

Increased Activity of MAPKAPK2 within Mesenchymal Cells as a Target for Inflammation-Associated Fibrosis in Crohn's Disease.

Impairment of Tissue-Resident Mesenchymal Stem Cells in Chronic Ulcerative Colitis and Crohn's Disease.

Activation PDGFR-α/AKT Mediated Signaling Pathways in Oral Squamous Cell Carcinoma by Mesenchymal Stem/Stromal Cells Promotes Anti-apoptosis and Decreased Sensitivity to Cisplatin.