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The brain penetrant PPARγ agonist leriglitazone restores multiple altered pathways in models of X-linked adrenoleukodystrophy.
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- Science Translational Medicine, 2021, v. 13, n. 596, p. 1, doi. 10.1126/scitranslmed.abc0555
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Clinical pharmacokinetics of leriglitazone and a translational approach using PBPK modeling to guide the selection of the starting dose in children.
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- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 6, p. 982, doi. 10.1002/psp4.13132
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- Article