OpenURL Connection Search

Select item for more details and to access through your institution.

Editorial: Immunopathology of Type 1 Diabetes.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.852963
By:
- Green, E. Allison;
- Cooke, Anne C.;
- Piganelli, Jon D.;
- Richardson, Sarah J.;
- Wen, Li;
- Wong, F. Susan
Publication type:
Article
T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01802
By:
- Ferguson, Ian D.;
- Griffin, Patricia;
- Michel, Joshua J.;
- Yano, Hiroshi;
- Gaffen, Sarah L.;
- Mueller, Robert G.;
- Dvergsten, Jeffrey A.;
- Piganelli, Jon D.;
- Rosenkranz, Margalit E.;
- Kietz, Daniel A.;
- Vallejo, Abbe N.
Publication type:
Article
Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases.
Published in:
PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0015384
By:
- Coudriet, Gina M.;
- Jing He;
- Trucco, Massimo;
- Mars, Wendy M.;
- Piganelli, Jon D.
Publication type:
Article
Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.
Published in:
Amino Acids, 2012, v. 42, n. 1, p. 95, doi. 10.1007/s00726-010-0603-6
By:
- Batinic-Haberle, Ines;
- Spasojevic, Ivan;
- Tse, Hubert M.;
- Tovmasyan, Artak;
- Rajic, Zrinka;
- St. Clair, Daret K.;
- Vujaskovic, Zeljko;
- Dewhirst, Mark W.;
- Piganelli, Jon D.
Publication type:
Article
An orally available cancer drug AZD6738 prevents type 1 diabetes.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1290058
By:
- Sugitani, Norie;
- Mason, Hannah R.;
- Campfield, Brian T.;
- Piganelli, Jon D.
Publication type:
Article
Epithelial NAD+ depletion drives mitochondrial dysfunction and contributes to intestinal inflammation.
Published in:
Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1231700
By:
- Novak, Elizabeth A.;
- Crawford, Erin C.;
- Mentrup, Heather L.;
- Griffith, Brian D.;
- Fletcher, David M.;
- Flanagan, Meredith R.;
- Schneider, Corinne;
- Firek, Brian;
- Rogers, Matthew B.;
- Morowitz, Michael J.;
- Piganelli, Jon D.;
- Qian Wang;
- Mollen, Kevin P.
Publication type:
Article
The Role of β Cell Stress and Neo-Epitopes in the Immunopathology of Type 1 Diabetes.
Published in:
Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.624590
By:
- Piganelli, Jon D.;
- Mamula, Mark J.;
- James, Eddie A.
Publication type:
Article
TRI microparticles prevent inflammatory arthritis in a collagen-induced arthritis model.
Published in:
PLoS ONE, 2020, v. 15, n. 9, p. 1, doi. 10.1371/journal.pone.0239396
By:
- Bassin, Ethan J.;
- Buckley, Abigail R.;
- Piganelli, Jon D.;
- Little, Steven R.
Publication type:
Article
Calcium/calmodulin-dependent protein kinase IV (CaMKIV) activation contributes to the pathogenesis of experimental colitis via inhibition of intestinal epithelial cell proliferation.
Published in:
FASEB Journal, 2019, v. 33, n. 1, p. 1330, doi. 10.1096/fj.201800535R
By:
- Cunningham, Kellie E.;
- Novak, Elizabeth A.;
- Vincent, Garret;
- Siow, Vei Shaun;
- Griffith, Brian D.;
- Ranganathan, Sarangarajan;
- Rosengart, Matthew R.;
- Piganelli, Jon D.;
- Mollen, Kevin P.
Publication type:
Article
Chromogranin A is an autoantigen in type 1 diabetes.
Published in:
Nature Immunology, 2010, v. 11, n. 3, p. 225, doi. 10.1038/ni.1844
By:
- Stadinski, Brian D.;
- Delong, Thomas;
- Reisdorph, Nichole;
- Reisdorph, Richard;
- Powell, Roger L.;
- Armstrong, Michael;
- Piganelli, Jon D.;
- Barbour, Gene;
- Bradley, Brenda;
- Crawford, Frances;
- Marrack, Philippa;
- Mahata, Sushil K.;
- Kappler, John W.;
- Haskins, Kathryn
Publication type:
Article
Glycolysis Inhibition Induces Functional and Metabolic Exhaustion of CD4+ T Cells in Type 1 Diabetes.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.669456
By:
- Martins, Christina P.;
- New, Lee A.;
- O'Connor, Erin C.;
- Previte, Dana M.;
- Cargill, Kasey R.;
- Tse, Isabelle L.;
- Sims- Lucas, Sunder;
- Piganelli, Jon D.
Publication type:
Article
Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes.
Published in:
Antioxidants, 2017, v. 6, n. 4, p. 85, doi. 10.3390/antiox6040085
By:
- Coudriet, Gina M.;
- Delmastro-Greenwood, Meghan M.;
- Previte, Dana M.;
- Marré, Meghan L.;
- O’Connor, Erin C.;
- Novak, Elizabeth A.;
- Vincent, Garret;
- Mollen, Kevin P.;
- Lee, Sojin;
- Dong, H. Henry;
- Piganelli, Jon D.
Publication type:
Article
Hepatocyte Growth Factor Regulates Inflammation in Type 2 Diabetes.
Published in:
Diabetes, 2007, v. 56, p. A695
By:
- Randa, Gina M.;
- Profozich, Jennifer;
- Yu Yang;
- Mars, Wendy M.;
- Piganelli, Jon D.
Publication type:
Article
Critical Role of Superoxide (02-) Production in the Pathogenesis of Autoimmune Diabetes (T1D).
Published in:
Diabetes, 2007, v. 56, p. A59
By:
- Thayer, Terri C.;
- Tse, Hubert M.;
- Steele, Chad;
- Piganelli, Jon D.;
- Mathews, Clayton E.
Publication type:
Article
Reactive Oxygen Species Generation Is Necessary for Autoimmune T cell Effector Function.
Published in:
Diabetes, 2007, v. 56, p. A58
By:
- Tse, Hubert M.;
- Thayer, Terri C.;
- Mathews, Clayton E.;
- Piganelli, Jon D.
Publication type:
Article
Modulatory Role of DR4- to DQ8-restricted CD4 T-Cell Responses and Type 1 Diabetes Susceptibility.
Published in:
Diabetes, 2006, v. 55, n. 12, p. 3455, doi. 10.2337/db06-0680
By:
- Xinhui Ge;
- Piganelli, Jon D.;
- Tse, Hubert M.;
- Bertera, Suzanne;
- Mathews, Clayton E.;
- Trucco, Massimo;
- Li Wen;
- Rudert, William A.
Publication type:
Article
Response of human islets to isolation stress and the effect of antioxidant treatment.
Published in:
2004
By:
- Bottino, Rita;
- Balamurugan, A. N.;
- Tse, Hubert;
- Thirunavukkarasu, C.;
- Xinhui Ge;
- Profozich, Jennifer;
- Milton, Martha;
- Ziegenfuss, Audra;
- Trucco, Massimo;
- Piganelli, Jon D.;
- Ge, Xinhui
Publication type:
journal article
Caspase-1 is not required for type 1 diabetes in the NOD mouse.
Published in:
2004
By:
- Schott, William H.;
- Haskell, Bradford D.;
- Choisy-Rossi, Caroline Morgane;
- Reifsnyder, Peter C.;
- Chervonsky, Alexander V.;
- Leiter, Edward H.;
- Tse, Hubert M.;
- Milton, Martha J.;
- Piganelli, Jon D.
Publication type:
journal article
Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound.
Published in:
2002
By:
- Bottino, Rita;
- Balamurugan, A.N.;
- Bertera, Suzaanne;
- Bertera, Suzanne;
- Pietropaolo, Massimo;
- Trucco, Massimo;
- Piganelli, Jon D.
Publication type:
journal article
A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone.
Published in:
2002
By:
- Piganelli, Jon D.;
- Flores, Sonia C.;
- Cruz, Coral;
- Koepp, Jeffrey;
- Batinic-Haberle, Ines;
- Crapo, James;
- Day, Brian;
- Kachadourian, Remy;
- Young, Rebekah;
- Bradley, Brenda;
- Haskins, Kathryn
Publication type:
journal article
Autoreactive T-cell responses: new technology in pursuit of an old nemesis.
Published in:
2007
By:
- Piganelli, Jon D.;
- Mathews, Clayton E.
Publication type:
Editorial
Oxidative Stress and Redox Modulation Potential in Type 1 Diabetes.
Published in:
Clinical & Developmental Immunology, 2011, p. 1, doi. 10.1155/2011/593863
By:
- Delmastro, Meghan M.;
- Piganelli, Jon D.
Publication type:
Article
Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes.
Published in:
Frontiers in Endocrinology, 2017, p. 1, doi. 10.3389/fendo.2017.00262
By:
- Marré, Meghan L.;
- Piganelli, Jon D.
Publication type:
Article
Preeclampsia Activates Circulating Immune Cells with Engagement of the NF- κB Pathway.
Published in:
American Journal of Reproductive Immunology, 2006, v. 56, n. 2, p. 135, doi. 10.1111/j.1600-0897.2006.00386.x
By:
- Luppi, Patrizia;
- Tse, Hubert;
- Lain, Kristine Y.;
- Markovic, Nina;
- Piganelli, Jon D.;
- DeLoia, Julie A.
Publication type:
Article
Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation.
Published in:
PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0175549
By:
- Previte, Dana M.;
- O’Connor, Erin C.;
- Novak, Elizabeth A.;
- Martins, Christina P.;
- Mollen, Kevin P.;
- Piganelli, Jon D.
Publication type:
Article
Auto-antigen and Immunomodulatory Agent-Based Approaches for Antigen-Specific Tolerance in NOD Mice.
Published in:
2021
By:
- Bassin, Ethan J.;
- Piganelli, Jon D.;
- Little, Steven R.
Publication type:
journal article
T cell epitopes and post-translationally modified epitopes in type 1 diabetes.
Published in:
2015
By:
- McGinty, John;
- Marré, Meghan;
- Bajzik, Veronique;
- Piganelli, Jon;
- James, Eddie;
- McGinty, John W;
- Marré, Meghan L;
- Piganelli, Jon D;
- James, Eddie A
Publication type:
journal article
Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.
Published in:
2018
By:
- Buitinga, Mijke;
- Callebaut, Aïsha;
- Câmara Sodré, Fernanda Marques;
- Crèvecoeur, Inne;
- Blahnik-Fagan, Gabriele;
- Mei-Ling Yang;
- Bugliani, Marco;
- Arribas-Layton, David;
- Marré, Meghan;
- Cook, Dana P.;
- Waelkens, Etienne;
- Mallone, Roberto;
- Piganelli, Jon D.;
- Marchetti, Piero;
- Mamula, Mark J.;
- Derua, Rita;
- James, Eddie A.;
- Mathieu, Chantal;
- Overbergh, Lut;
- Marques Câmara Sodré, Fernanda
Publication type:
journal article
Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.
Published in:
2018
By:
- Marre, Meghan L.;
- McGinty, John W.;
- I-Ting Chow;
- DeNicola, Megan E.;
- Beck, Noah W.;
- Kent, Sally C.;
- Powers, Alvin C.;
- Bottino, Rita;
- Harlan, David M.;
- Greenbaum, Carla J.;
- Kwok, William W.;
- Piganelli, Jon D.;
- James, Eddie A.;
- Chow, I-Ting
Publication type:
journal article
Loss of NOX-Derived Superoxide Exacerbates Diabetogenic CD4 T-Cell Effector Responses in Type 1 Diabetes.
Published in:
2015
By:
- Padgett, Lindsey E.;
- Anderson, Brian;
- Chao Liu;
- Ganini, Douglas;
- Mason, Ronald P.;
- Piganelli, Jon D.;
- Mathews, Clayton E.;
- Tse, Hubert M.;
- Liu, Chao
Publication type:
journal article
Cytokine and Chemokine Production by Human Pancreatic Islets Upon Enterovirus Infection.
Published in:
Diabetes, 2012, v. 61, n. 8, p. 2030, doi. 10.2337/db11-1547
By:
- Schulte, Barbara M.;
- Lanke, Kjerstin H. W.;
- Piganelli, Jon D.;
- Kers-Rebel, Esther D.;
- Bottino, Rita;
- Trucco, Massimo;
- Huijbens, Richard J. F.;
- Radstake, Timothy R. D. J.;
- Engelse, Marten A.;
- de Koning, Eelco J. P.;
- Galama, Jochem M.;
- Adema, Gosse J.;
- van Kuppeveld, Frank J. M.
Publication type:
Article
Modulation of Redox Balance Leaves Murine Diabetogenic TH1 T Cells "LAG-3-ing" Behind.
Published in:
Diabetes, 2012, v. 61, n. 7, p. 1760, doi. 10.2337/db11-1591
By:
- Delmastro, Meghan M.;
- Styche, Alexis J.;
- Trucco, Massimo M.;
- Workman, Creg J.;
- Vignali, Dario A. A.;
- Piganelli, Jon D.
Publication type:
Article
Superoxide Production by Macrophages and T Cells Is Critical for the Induction of Autoreactivity and Type 1 Diabetes.
Published in:
Diabetes, 2011, v. 60, n. 8, p. 2144, doi. 10.2337/db10-1222
By:
- Thayer, Terri C.;
- Delano, Matthew;
- Liu, Chao;
- Chen, Jing;
- Padgett, Lindsey E.;
- Tse, Hubert M.;
- Annamali, Mani;
- Piganelli, Jon D.;
- Moldawer, Lyle L.;
- Mathews, Clayton E.
Publication type:
Article
Redox Modulation Protects Islets From Transplant-Related Injury.
Published in:
Diabetes, 2010, v. 59, n. 7, p. 1731, doi. 10.2337/db09-0588
By:
- Sklavos, Martha M.;
- Bertera, Suzanne;
- Tse, Hubert M.;
- Bottino, Rita;
- He, Jing;
- Beilke, Joshua N.;
- Coulombe, Marilyne G.;
- Gill, Ronald G.;
- Crapo, James D.;
- Trucco, Massimo;
- Piganelli, Jon D.
Publication type:
Article
Phagocytosis of enterovirus-infected pancreatic beta-cells triggers innate immune responses in human dendritic cells.
Published in:
2010
By:
- Schulte BM;
- Kramer M;
- Ansems M;
- Lanke KH;
- van Doremalen N;
- Piganelli JD;
- Bottino R;
- Trucco M;
- Galama JM;
- Adema GJ;
- van Kuppeveld FJ;
- Schulte, Barbara M;
- Kramer, Matthijs;
- Ansems, Marleen;
- Lanke, Kjerstin H W;
- van Doremalen, Neeltje;
- Piganelli, Jon D;
- Bottino, Rita;
- Trucco, Massimo;
- Galama, Jochem M D
Publication type:
journal article
Phagocytosis of Enterovirus-Infected Pancreatic β-Cells Triggers Innate Immune Responses in Human Dendritic Cells.
Published in:
Diabetes, 2010, v. 59, n. 5, p. 1182, doi. 10.2337/db09-1071
By:
- Schulte, Barbara M.;
- Kramer, Matthijs;
- Ansems, Marleen;
- Lanke, Kjerstin H. W.;
- van Doremalen, Neeltje;
- Piganelli, Jon D.;
- Bottino, Rita;
- Trucco, Massimo;
- Galama, Jochem M. D.;
- Adema, Gosse J.;
- van Kuppeveld, Frank J. M.
Publication type:
Article

Found: 36

Editorial: Immunopathology of Type 1 Diabetes.

T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis.

Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases.

Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.

An orally available cancer drug AZD6738 prevents type 1 diabetes.

Epithelial NAD<sup>+</sup> depletion drives mitochondrial dysfunction and contributes to intestinal inflammation.

The Role of β Cell Stress and Neo-Epitopes in the Immunopathology of Type 1 Diabetes.

TRI microparticles prevent inflammatory arthritis in a collagen-induced arthritis model.

Calcium/calmodulin-dependent protein kinase IV (CaMKIV) activation contributes to the pathogenesis of experimental colitis via inhibition of intestinal epithelial cell proliferation.

Chromogranin A is an autoantigen in type 1 diabetes.

Glycolysis Inhibition Induces Functional and Metabolic Exhaustion of CD4<sup>+</sup> T Cells in Type 1 Diabetes.

Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes.

Hepatocyte Growth Factor Regulates Inflammation in Type 2 Diabetes.

Critical Role of Superoxide (02-) Production in the Pathogenesis of Autoimmune Diabetes (T1D).

Reactive Oxygen Species Generation Is Necessary for Autoimmune T cell Effector Function.

Modulatory Role of DR4- to DQ8-restricted CD4 T-Cell Responses and Type 1 Diabetes Susceptibility.

Response of human islets to isolation stress and the effect of antioxidant treatment.

Caspase-1 is not required for type 1 diabetes in the NOD mouse.

Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound.

A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone.

Autoreactive T-cell responses: new technology in pursuit of an old nemesis.

Oxidative Stress and Redox Modulation Potential in Type 1 Diabetes.

Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes.

Preeclampsia Activates Circulating Immune Cells with Engagement of the NF- κB Pathway.

Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4<sup>+</sup> T cell activation.

Auto-antigen and Immunomodulatory Agent-Based Approaches for Antigen-Specific Tolerance in NOD Mice.

T cell epitopes and post-translationally modified epitopes in type 1 diabetes.

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.

Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4<sup>+</sup> T Cells in Patients With Type 1 Diabetes.

Loss of NOX-Derived Superoxide Exacerbates Diabetogenic CD4 T-Cell Effector Responses in Type 1 Diabetes.

Cytokine and Chemokine Production by Human Pancreatic Islets Upon Enterovirus Infection.

Modulation of Redox Balance Leaves Murine Diabetogenic TH1 T Cells "LAG-3-ing" Behind.

Superoxide Production by Macrophages and T Cells Is Critical for the Induction of Autoreactivity and Type 1 Diabetes.

Redox Modulation Protects Islets From Transplant-Related Injury.

Phagocytosis of enterovirus-infected pancreatic beta-cells triggers innate immune responses in human dendritic cells.

Phagocytosis of Enterovirus-Infected Pancreatic β-Cells Triggers Innate Immune Responses in Human Dendritic Cells.