Works by Pierce, Raymond J.

Results: 33
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    Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni.

    Published in:
    PLoS Neglected Tropical Diseases, 2020, v. 14, n. 7, p. 1, doi. 10.1371/journal.pntd.0008332
    By:
    • Coutinho Carneiro, Vitor;
    • de Abreu da Silva, Isabel Caetano;
    • Amaral, Murilo Sena;
    • Pereira, Adriana S. A.;
    • Silveira, Gilbert Oliveira;
    • Pires, David da Silva;
    • Verjovski-Almeida, Sergio;
    • Dekker, Frank J.;
    • Rotili, Dante;
    • Mai, Antonello;
    • Lopes-Torres, Eduardo José;
    • Robaa, Dina;
    • Sippl, Wolfgang;
    • Pierce, Raymond J.;
    • Borrello, M. Teresa;
    • Ganesan, A.;
    • Lancelot, Julien;
    • Thiengo, Silvana;
    • Fernandez, Monica Ammon;
    • Vicentino, Amanda Roberta Revoredo
    Publication type:
    Article
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    Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni.

    Published in:
    PLoS Neglected Tropical Diseases, 2021, v. 15, n. 11, p. 1, doi. 10.1371/journal.pntd.0009503
    By:
    • Pagliazzo, Lucile;
    • Caby, Stéphanie;
    • Lancelot, Julien;
    • Salomé-Desnoulez, Sophie;
    • Saliou, Jean-Michel;
    • Heimburg, Tino;
    • Chassat, Thierry;
    • Cailliau, Katia;
    • Sippl, Wolfgang;
    • Vicogne, Jérôme;
    • Pierce, Raymond J.
    Publication type:
    Article
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    Front Cover: Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis (ChemMedChem 15/2018).

    Published in:
    ChemMedChem, 2018, v. 13, n. 15, p. 1488, doi. 10.1002/cmdc.201800494
    By:
    • Bayer, Theresa;
    • Chakrabarti, Alokta;
    • Lancelot, Julien;
    • Shaik, Tajith B.;
    • Hausmann, Kristin;
    • Melesina, Jelena;
    • Schmidtkunz, Karin;
    • Marek, Martin;
    • Erdmann, Frank;
    • Schmidt, Matthias;
    • Robaa, Dina;
    • Romier, Christophe;
    • Pierce, Raymond J.;
    • Jung, Manfred;
    • Sippl, Wolfgang
    Publication type:
    Article
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    Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis.

    Published in:
    ChemMedChem, 2018, v. 13, n. 15, p. 1517, doi. 10.1002/cmdc.201800238
    By:
    • Bayer, Theresa;
    • Chakrabarti, Alokta;
    • Lancelot, Julien;
    • Shaik, Tajith B.;
    • Hausmann, Kristin;
    • Melesina, Jelena;
    • Schmidtkunz, Karin;
    • Marek, Martin;
    • Erdmann, Frank;
    • Schmidt, Matthias;
    • Robaa, Dina;
    • Romier, Christophe;
    • Pierce, Raymond J.;
    • Jung, Manfred;
    • Sippl, Wolfgang
    Publication type:
    Article
    20

    Antiplasmodial Activity Is an Ancient and Conserved Feature of Tick Defensins.

    Published in:
    Frontiers in Microbiology, 2016, v. 7, p. 1, doi. 10.3389/fmicb.2016.01682
    By:
    • Bouchut, Anne;
    • Pierrot, Christine;
    • Pierce, Raymond J.;
    • Khalife, Jamal;
    • Cabezas-Cruz, Alejandro;
    • Kotsyfakis, Michalis;
    • Valdés, James J.;
    • Tonk, Miray;
    • Rahnamaeian, Mohammad;
    • Vilcinskas, Andreas;
    • Da Silva Junior, Pedro Ismael;
    • Gosti, Françoise
    Publication type:
    Article
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    Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke <i>Schistosoma mansoni</i>.

    Published in:
    PLoS Pathogens, 2013, v. 9, n. 9, p. 1, doi. 10.1371/journal.ppat.1003645
    By:
    • Marek, Martin;
    • Kannan, Srinivasaraghavan;
    • Hauser, Alexander-Thomas;
    • Moraes Mourão, Marina;
    • Caby, Stéphanie;
    • Cura, Vincent;
    • Stolfa, Diana A.;
    • Schmidtkunz, Karin;
    • Lancelot, Julien;
    • Andrade, Luiza;
    • Renaud, Jean-Paul;
    • Oliveira, Guilherme;
    • Sippl, Wolfgang;
    • Jung, Manfred;
    • Cavarelli, Jean;
    • Pierce, Raymond J.;
    • Romier, Christophe
    Publication type:
    Article
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    Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and noncoding RNA metabolism.

    Published in:
    PLoS Neglected Tropical Diseases, 2018, v. 12, n. 10, p. 1, doi. 10.1371/journal.pntd.0006873
    By:
    • Pereira, Adriana S. A.;
    • Amaral, Murilo S.;
    • Vasconcelos, Elton J. R.;
    • Pires, David S.;
    • Asif, Huma;
    • daSilva, Lucas F.;
    • Morales-Vicente, David A.;
    • Carneiro, Vitor C.;
    • Angeli, Claudia B.;
    • Palmisano, Giuseppe;
    • Fantappie, Marcelo R.;
    • Pierce, Raymond J.;
    • Setubal, João C.;
    • Verjovski-Almeida, Sergio
    Publication type:
    Article