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Mucosal IFNλ1 mRNA-based immunomodulation effectively reduces SARS-CoV-2 induced mortality in mice.
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- EMBO Reports, 2024, v. 25, n. 9, p. 3777, doi. 10.1038/s44319-024-00216-4
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ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion.
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- EMBO Reports, 2022, v. 23, n. 6, p. 1, doi. 10.15252/embr.202154305
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The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses.
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- eLife, 2022, p. 1, doi. 10.7554/eLife.76804
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Viral targeting of TFIIB impairs de novo polymerase II recruitment and affects antiviral immunity.
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- PLoS Pathogens, 2018, v. 14, n. 5, p. 1, doi. 10.1371/journal.ppat.1006980
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High-resolution kinetic characterization of the RIG-I-signaling pathway and the antiviral response.
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- Life Science Alliance, 2023, v. 6, n. 10, p. 1, doi. 10.26508/lsa.202302059
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- Article
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.
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- Nucleic Acids Research, 2022, v. 50, n. 1, p. 333, doi. 10.1093/nar/gkab1248
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Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17189-2
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The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription.
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- Microorganisms, 2020, v. 8, n. 6, p. 790, doi. 10.3390/microorganisms8060790
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MDM2 Influences ACE2 Stability and SARS-CoV-2 Uptake.
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- Viruses (1999-4915), 2023, v. 15, n. 8, p. 1763, doi. 10.3390/v15081763
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- Article
Influenza A Virus Infection Reactivates Human Endogenous Retroviruses Associated with Modulation of Antiviral Immunity.
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- Viruses (1999-4915), 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/v14071591
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System-Based Approaches to Delineate the Antiviral Innate Immune Landscape.
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- Viruses (1999-4915), 2020, v. 12, n. 10, p. 1196, doi. 10.3390/v12101196
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- Article
Persistent Innate Immune Stimulation Results in IRF3-Mediated but Caspase-Independent Cytostasis.
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- Viruses (1999-4915), 2020, v. 12, n. 6, p. 635, doi. 10.3390/v12060635
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- Article
Chasing Intracellular Zika Virus Using Proteomics.
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- Viruses (1999-4915), 2019, v. 11, n. 9, p. 878, doi. 10.3390/v11090878
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- Article
Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA.
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- PLoS Pathogens, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.ppat.1003663
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Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity.
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- Cellular Microbiology, 2014, v. 16, n. 6, p. 834, doi. 10.1111/cmi.12241
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Chemoenzymatic Total Synthesis of Sorbicatechol Structural Analogues and Evaluation of Their Antiviral Potential.
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- ChemBioChem, 2020, v. 21, n. 4, p. 492, doi. 10.1002/cbic.201900472
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Structural basis for viral 5?-PPP-RNA recognition by human IFIT proteins.
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- Nature, 2013, v. 494, n. 7435, p. 60, doi. 10.1038/nature11783
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Viral immune modulators perturb the human molecular network by common and unique strategies.
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- Nature, 2012, v. 487, n. 7408, p. 486, doi. 10.1038/nature11289
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- Article
IFIT1 is an antiviral protein that recognizes 5?-triphosphate RNA.
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- Nature Immunology, 2011, v. 12, n. 7, p. 624, doi. 10.1038/ni.2048
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Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27192-w
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NUDT2 initiates viral RNA degradation by removal of 5′-phosphates.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27239-y
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- Article
Human cytomegalovirus-induced host protein citrullination is crucial for viral replication.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24178-6
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Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting.
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- Cell Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41421-024-00672-1
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mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3.
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- Nature Communications, 2015, v. 6, n. 9, p. 8192, doi. 10.1038/ncomms9192
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Processing of Genome 59 Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction.
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- PLoS ONE, 2008, v. 3, n. 4, p. 1, doi. 10.1371/journal.pone.0002032
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mRNA 3'UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40469-6
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Zika virus remodelled ER membranes contain proviral factors involved in redox and methylation pathways.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43665-6
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Genotoxic stress in constitutive trisomies induces autophagy and the innate immune response via the cGAS-STING pathway.
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- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02278-9
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Disruption of disulfides within RBD of SARS-CoV-2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs.
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- FASEB Journal, 2021, v. 35, n. 6, p. 1, doi. 10.1096/fj.202100560R
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Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages.
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- EMBO Journal, 2023, v. 42, n. 23, p. 1, doi. 10.15252/embj.2022113279
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The alternative cap-binding complex is required for antiviral defense in vivo.
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- PLoS Pathogens, 2019, v. 15, n. 12, p. N.PAG, doi. 10.1371/journal.ppat.1008155
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A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle.
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- PLoS Pathogens, 2019, v. 15, n. 5, p. 1, doi. 10.1371/journal.ppat.1007736
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