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Single and multiple ascending dose studies in healthy volunteers to assess the safety and PK of LY3372689, an inhibitor of the O‐GlcNAcase (OGA) enzyme.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057728
By:
- Lowe, Stephen L;
- Goldsmith, Paul;
- Phipps, Krista M;
- Kevin, Donnelly B;
- Biglan, Kevin;
- Mancini, Michele;
- Nuthall, Hugh Norman;
- Mergott, Dustin J.;
- Kielbasa, William
Publication type:
Article
Brain target occupancy of LY3372689, an inhibitor of the O‐GlcNAcase (OGA) enzyme, following administration of single and multiple doses to healthy volunteers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057774
By:
- Kielbasa, William;
- Shcherbinin, Sergey;
- Goldsmith, Paul;
- Phipps, Krista M;
- Biglan, Kevin;
- Mancini, Michele;
- Russell, David;
- Constantinescu, Cristian;
- Gunn, Roger N;
- Nuthall, Hugh Norman;
- Mergott, Dustin J.;
- Lowe, Stephen L;
- Collins, Emily C
Publication type:
Article
Brain target occupancy of LY3372689, an inhibitor of the O‐GlcNAcase (OGA) enzyme: Translation from rat to human: Neuroimaging / evaluating treatments.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040558
By:
- Shcherbinin, Sergey;
- Kielbasa, William;
- Dubois, Susan;
- Lowe, Stephen L;
- Phipps, Krista M;
- Tseng, James;
- Kevin, Donnelly B;
- Natanegara, Fanni;
- Warner, Susan;
- Dreyfus, Nicolas;
- Lindsay‐Scott, Peter;
- Hawk, Mai Khanh;
- McDonald, Nicholas;
- Zhang, Xiaoyu;
- Gilmore, Julie A;
- Biglan, Kevin;
- Mergott, Dustin J;
- Russell, David;
- Gunn, Roger N;
- Constantinescu, Cristian
Publication type:
Article
A single ascending dose study in healthy volunteers to assess the safety and PK of LY3372689, an inhibitor of O‐GlcNAcase (OGA) enzyme: Human/Human trials: Anti‐tau.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040473
By:
- Kielbasa, William;
- Phipps, Krista M;
- Tseng, James;
- Natanegara, Fanni;
- Cheng, Eden;
- Monk, Scott A.;
- Bundgaard, Christoffer;
- Kevin, Donnelly B.;
- Nuthall, Hugh Norman;
- McDonald, Nicholas;
- Lindsay‐Scott, Peter;
- Dreyfus, Nicolas;
- Hawk, Mai Khanh;
- Warner, Susan;
- Biglan, Kevin;
- Gilmore, Julie A.;
- Zhang, Xiaoyu;
- Mergott, Dustin J.;
- Lowe, Stephen L.
Publication type:
Article

Found: 4

Single and multiple ascending dose studies in healthy volunteers to assess the safety and PK of LY3372689, an inhibitor of the O‐GlcNAcase (OGA) enzyme.

Brain target occupancy of LY3372689, an inhibitor of the O‐GlcNAcase (OGA) enzyme, following administration of single and multiple doses to healthy volunteers.

Brain target occupancy of LY3372689, an inhibitor of the O‐GlcNAcase (OGA) enzyme: Translation from rat to human: Neuroimaging / evaluating treatments.

A single ascending dose study in healthy volunteers to assess the safety and PK of LY3372689, an inhibitor of O‐GlcNAcase (OGA) enzyme: Human/Human trials: Anti‐tau.