Works by Philpot, Benjamin D.

Results: 59

Ictal neural oscillatory alterations precede sudden unexpected death in epilepsy.

Published in:

Brain Communications, 2022, v. 4, n. 2, p. 1, doi. 10.1093/braincomms/fcac073

By:

Bin Gu;
Levine, Noah G.;
Wenjing Xu;
Lynch, Rachel M.;
Pardo-Manuel de Villena, Fernando;
Philpot, Benjamin D.

Publication type:

Article

Region and Cell Type Distribution of TCF4 in the Postnatal Mouse Brain.

Published in:

Frontiers in Neuroanatomy, 2020, v. 14, p. 1, doi. 10.3389/fnana.2020.00042

By:

Kim, Hyojin;
Berens, Noah C.;
Ochandarena, Nicole E.;
Philpot, Benjamin D.

Publication type:

Article

Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00652-y

By:

Nagendran, Tharkika;
Larsen, Rylan S.;
Bigler, Rebecca L.;
Frost, Shawn B.;
Philpot, Benjamin D.;
Nudo, Randolph J.;
Taylor, Anne Marion

Publication type:

Article

Evaluation of electroencephalography biomarkers for Angelman syndrome during overnight sleep.

Published in:

Autism Research: Official Journal of the International Society for Autism Research, 2022, v. 15, n. 6, p. 1031, doi. 10.1002/aur.2709

By:

Levin, Yuval;
Hosamane, Nishitha S.;
McNair, Taylor E.;
Kunnam, Shrujana S.;
Philpot, Benjamin D.;
Fan, Zheng;
Sidorov, Michael S.

Publication type:

Article

Visual Deprivation Modifies Both Presynaptic Glutamate Release and the Composition of Perisynaptic/Extrasynaptic NMDA Receptors in Adult Visual Cortex.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 50, p. 11684, doi. 10.1523/JNEUROSCI.4362-05.2005

By:

Yashiro, Koji;
Corlew, Rebekah;
Philpot, Benjamin D.

Publication type:

Article

Evidence for Altered NMDA Receptor Function as a Basis for Metaplasticity in Visual Cortex.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 13, p. 5583, doi. 10.1523/JNEUROSCI.23-13-05583.2003

By:

Philpot, Benjamin D.;
Espinosa, Juan S.;
Bear, Mark F.

Publication type:

Article

Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility.

Published in:

Epilepsia (Series 4), 2020, v. 61, n. 9, p. 2010, doi. 10.1111/epi.16617

By:

Gu, Bin;
Shorter, John R.;
Williams, Lucy H.;
Bell, Timothy A.;
Hock, Pablo;
Dalton, Katherine A.;
Pan, Yiyun;
Miller, Darla R.;
Shaw, Ginger D.;
Philpot, Benjamin D.;
Pardo‐Manuel de Villena, Fernando

Publication type:

Article

Significance of N-methyl-d-aspartate (NMDA) receptor-mediated signaling in human keratinocytes.

Published in:

Journal of Cellular Physiology, 2004, v. 200, n. 2, p. 309, doi. 10.1002/jcp.20010

By:

Walter K. Nahm;
Benjamin D. Philpot;
Michelle M. Adams;
Evangelos V. Badiavas;
Linda H. Zhou;
Janet Butmarc;
Mark F. Bear

Publication type:

Article

Topoisomerases facilitate transcription of long genes linked to autism.

Published in:

Nature, 2013, v. 501, n. 7465, p. 58, doi. 10.1038/nature12504

By:

King, Ian F.;
Yandava, Chandri N.;
Mabb, Angela M.;
Hsiao, Jack S.;
Huang, Hsien-Sung;
Pearson, Brandon L.;
Calabrese, J. Mauro;
Starmer, Joshua;
Parker, Joel S.;
Magnuson, Terry;
Chamberlain, Stormy J.;
Philpot, Benjamin D.;
Zylka, Mark J.

Publication type:

Article

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons.

Published in:

Nature, 2012, v. 481, n. 7380, p. 185, doi. 10.1038/nature10726

By:

Huang, Hsien-Sung;
Allen, John A.;
Mabb, Angela M.;
King, Ian F.;
Miriyala, Jayalakshmi;
Taylor-Blake, Bonnie;
Sciaky, Noah;
Dutton, J. Walter;
Lee, Hyeong-Min;
Chen, Xin;
Jin, Jian;
Bridges, Arlene S.;
Zylka, Mark J.;
Roth, Bryan L.;
Philpot, Benjamin D.

Publication type:

Article

Heterogeneity in the progression of retinal pathologies in mice harboring patient mimicking Impg2 mutations.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 5, p. 448, doi. 10.1093/hmg/ddad199

By:

Williams, Brittany N;
Draper, Adam;
Lang, Patrick F;
Lewis, Tylor R;
Smith, Audrey L;
Mayerl, Steven J;
Rougié, Marie;
Simon, Jeremy M;
Arshavsky, Vadim Y;
Greenwald, Scott H;
Gamm, David M;
Pinilla, Isabel;
Philpot, Benjamin D

Publication type:

Article

Ube3a unsilencer for the potential treatment of Angelman syndrome.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49788-8

By:

Vihma, Hanna;
Li, Kelin;
Welton-Arndt, Anna;
Smith, Audrey L.;
Bettadapur, Kiran R.;
Gilmore, Rachel B.;
Gao, Eric;
Cotney, Justin L.;
Huang, Hsueh-Cheng;
Collins, Jon L.;
Chamberlain, Stormy J.;
Lee, Hyeong-Min;
Aubé, Jeffrey;
Philpot, Benjamin D.

Publication type:

Article

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.

Published in:

PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0156439

By:

Mabb, Angela M.;
Simon, Jeremy M.;
King, Ian F.;
Lee, Hyeong-Min;
An, Lin-Kun;
Philpot, Benjamin D.;
Zylka, Mark J.

Publication type:

Article

Enhanced Operant Extinction and Prefrontal Excitability in a Mouse Model of Angelman Syndrome.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 11, p. 2671, doi. 10.1523/JNEUROSCI.2828-17.2018

By:

Sidorov, Michael S.;
Judson, Matthew C.;
Hyojin Kim;
Rougie, Marie;
Ferrer, Alejandra I.;
Nikolova, Viktoriya D.;
Riddick, Natallia V.;
Moy, Sheryl S.;
Philpot, Benjamin D.

Publication type:

Article

Common Pathophysiology in Multiple Mouse Models of Pitt-Hopkins Syndrome.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 4, p. 918, doi. 10.1523/JNEUROSCI.1305-17.2017

By:

Thaxton, Courtney;
Kloth, Alexander D.;
Clark, Ellen P.;
Philpot, Benjamin D.;
Moy, Sheryl S.;
Chitwood, Raymond A.

Publication type:

Article

Enhanced Nociception in Angelman Syndrome Model Mice.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 42, p. 10230, doi. 10.1523/JNEUROSCI.1018-17.2017

By:

McCoy, Eric S.;
Taylor-Blake, Bonnie;
Aita, Megumi;
Simon, Jeremy M.;
Philpot, Benjamin D.;
Zylka, Mark J.

Publication type:

Article

Decreased Axon Caliber Underlies Loss of Fiber Tract Integrity, Disproportional Reductions in White Matter Volume, and Microcephaly in Angelman Syndrome Model Mice.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 31, p. 7347, doi. 10.1523/JNEUROSCI.0037-17.2017

By:

Judson, Matthew C.;
Burette, Alain C.;
Thaxton, Courtney L.;
Pribisko, Alaine L.;
Shen, Mark D.;
Rumple, Ashley M.;
Del Cid, Wilmer A.;
Paniagua, Beatriz;
Styner, Martin;
Weinberg, Richard J.;
Philpot, Benjamin D.

Publication type:

Article

Maternal Loss of Ube3a Impairs Experience-Driven Dendritic Spine Maintenance in the Developing Visual Cortex.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 17, p. 4888, doi. 10.1523/JNEUROSCI.4204-15.2016

By:

Kim, Hyojin;
Kunz, Portia A.;
Mooney, Richard;
Philpot, Benjamin D.;
Smith, Spencer L.

Publication type:

Article

Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 40, p. 13587, doi. 10.1523/JNEUROSCI.2194-15.2015

By:

Ehlen, J. Christopher;
Jones, Kelly A.;
Pinckney, Lennisha;
Gray, Cloe L.;
Burette, Susan;
Weinberg, Richard J.;
Evans, Jennifer A.;
Brager, Allison J.;
Zylka, Mark J.;
Paul, Ketema N.;
Philpot, Benjamin D.;
DeBruyne, Jason P.

Publication type:

Article

Presynaptic NMDA Receptor Mechanisms for Enhancing Spontaneous Neurotransmitter Release.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 18, p. 7762, doi. 10.1523/JNEUROSCI.2482-12.2013

By:

Kunz, Portia A.;
Roberts, Adam C.;
Philpot, Benjamin D.

Publication type:

Article

Transferable neuronal mini-cultures to accelerate screening in primary and induced pluripotent stem cell-derived neurons.

Published in:

Scientific Reports, 2015, p. 8353, doi. 10.1038/srep08353

By:

Niedringhaus, Mark;
Dumitru, Raluca;
Mabb, Angela M.;
Wang, Yuli;
Philpot, Benjamin D.;
Allbritton, Nancy L.;
Taylor, Anne Marion

Publication type:

Article

Presynaptic NMDA Receptors: Newly Appreciated Roles in Cortical Synaptic Function and Plasticity.

Published in:

Neuroscientist, 2008, v. 14, n. 6, p. 609, doi. 10.1177/1073858408322675

By:

Corlew, Rebekah;
Brasier, Daniel J.;
Feldman, Daniel E.;
Philpot, Benjamin D.

Publication type:

Article

Delayed loss of UBE3A reduces the expression of Angelman syndrome-associated phenotypes.

Published in:

Molecular Autism, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13229-019-0277-1

By:

Sonzogni, Monica;
Hakonen, Johanna;
Bernabé Kleijn, Mireia;
Silva-Santos, Sara;
Judson, Matthew C.;
Philpot, Benjamin D.;
van Woerden, Geeske M.;
Elgersma, Ype

Publication type:

Article

Subcellular organization of UBE3A in human cerebral cortex.

Published in:

Molecular Autism, 2018, v. 9, n. 1, p. N.PAG, doi. 10.1186/s13229-018-0238-0

By:

Burette, Alain C.;
Judson, Matthew C.;
Li, Alissa N.;
Chang, Edward F.;
Seeley, William W.;
Philpot, Benjamin D.;
Weinberg, Richard J.

Publication type:

Article

Characterization and structure-activity relationships of indenoisoquinoline-derived topoisomerase I inhibitors in unsilencing the dormant Ube3a gene associated with Angelman syndrome.

Published in:

Molecular Autism, 2018, v. 9, n. 1, p. N.PAG, doi. 10.1186/s13229-018-0228-2

By:

Lee, Hyeong-Min;
Clark, Ellen P.;
Kuijer, M. Bram;
Cushman, Mark;
Pommier, Yves;
Philpot, Benjamin D.

Publication type:

Article

Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of Tcf4 expression.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.72290

By:

Hyojin Kim;
Gao, Eric B.;
Draper, Adam;
Berens, Noah C.;
Vihma, Hanna;
Xinyuan Zhang;
Higashi-Howard, Alexandra;
Simon, Jeremy M.;
Kennedy, Andrew J.;
Philpot, Benjamin D.

Publication type:

Article

Internalization of ionotropic glutamate receptors in response to mGluR activation.

Published in:

Nature Neuroscience, 2001, v. 4, n. 11, p. 1079, doi. 10.1038/nn746

By:

Snyder, Eric M.;
Philpot, Benjamin D.;
Huber, Kimberly M.;
Dong, Xin;
Fallon, Justin R.;
Bear, Mark F.

Publication type:

Article

Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo.

Published in:

Nature Neuroscience, 1999, v. 2, n. 4, p. 352, doi. 10.1038/7263

By:

Quinlan, Elizabeth M.;
Philpot, Benjamin D.;
Huganir, Richard L.;
Bear, Mark F.

Publication type:

Article

NR3A-containing NMDARs promote neurotransmitter release and spike timing-dependent plasticity.

Published in:

Nature Neuroscience, 2011, v. 14, n. 3, p. 338, doi. 10.1038/nn.2750

By:

Larsen, Rylan S.;
Corlew, Rebekah J.;
Henson, Maile A.;
Roberts, Adam C.;
Mishina, Masayoshi;
Watanabe, Masahiko;
Lipton, Stuart A.;
Nakanishi, Nobuki;
Pérez-Otaño, Isabel;
Weinberg, Richard J.;
Philpot, Benjamin D.

Publication type:

Article

Ube3a is required for experience-dependent maturation of the neocortex.

Published in:

Nature Neuroscience, 2009, v. 12, n. 6, p. 777, doi. 10.1038/nn.2327

By:

Yashiro, Koji;
Riday, Thorfinn T.;
Condon, Kathryn H.;
Roberts, Adam C.;
Bernardo, Danilo R.;
Prakash, Rohit;
Weinberg, Richard J.;
Ehlers, Michael D.;
Philpot, Benjamin D.

Publication type:

Article

Developmental Regulation of the NMDA Receptor Subunits, NR3A and NR1, in Human Prefrontal Cortex.

Published in:

Cerebral Cortex, 2008, v. 18, n. 11, p. 2560, doi. 10.1093/cercor/bhn017

By:

Henson, Maile A.;
Roberts, Adam C.;
Salimi, Kayvon;
Vadlamudi, Swarooparani;
Hamer, Robert M.;
Gilmore, John H.;
Jarskog, L. Fredrik;
Philpot, Benjamin D.

Publication type:

Article

Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation.

Published in:

Nature Communications, 2016, v. 7, n. 2, p. 10702, doi. 10.1038/ncomms10702

By:

Berrios, Janet;
Stamatakis, Alice M.;
Kantak, Pranish A.;
McElligott, Zoe A.;
Judson, Matthew C.;
Aita, Megumi;
Rougie, Marie;
Stuber, Garret D.;
Philpot, Benjamin D.

Publication type:

Article

Subcellular organization of UBE3A in neurons.

Published in:

Journal of Comparative Neurology, 2017, v. 525, n. 2, p. 233, doi. 10.1002/cne.24063

By:

Burette, Alain C.;
Judson, Matthew C.;
Burette, Susan;
Phend, Kristen D.;
Philpot, Benjamin D.;
Weinberg, Richard J.

Publication type:

Article

Subcellular organization of UBE3A in neurons.

Published in:

Journal of Comparative Neurology, 2017, v. 525, n. 2, p. spc1, doi. 10.1002/cne.24143

By:

Burette, Alain C.;
Judson, Matthew C.;
Burette, Susan;
Phend, Kristen D.;
Philpot, Benjamin D.;
Weinberg, Richard J.

Publication type:

Article

Allelic specificity of Ube3a Expression In The Mouse Brain During Postnatal Development.

Published in:

Journal of Comparative Neurology, 2014, v. 522, n. 8, p. 1874, doi. 10.1002/cne.23507

By:

Judson, Matthew C.;
Sosa‐Pagan, Jason O.;
Del Cid, Wilmer A.;
Han, Ji Eun;
Philpot, Benjamin D.

Publication type:

Article

Persistent neuronal Ube3a expression in the suprachiasmatic nucleus of Angelman syndrome model mice.

Published in:

Scientific Reports, 2016, p. 28238, doi. 10.1038/srep28238

By:

Jones, Kelly A.;
Han, Ji Eun;
DeBruyne, Jason P.;
Philpot, Benjamin D.

Publication type:

Article

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 15, p. 3093, doi. 10.1093/hmg/ddr212

By:

Wang, Xiaoming;
McCoy, Portia A.;
Rodriguiz, Ramona M.;
Pan, Yanzhen;
Je, H. Shawn;
Roberts, Adam C.;
Kim, Caroline J.;
Berrios, Janet;
Colvin, Jennifer S.;
Bousquet-Moore, Danielle;
Lorenzo, Isabel;
Wu, Gangyi;
Weinberg, Richard J.;
Ehlers, Michael D.;
Philpot, Benjamin D.;
Beaudet, Arthur L.;
Wetsel, William C.;
Jiang, Yong-hui

Publication type:

Article

<i>Snx14</i> Regulates Neuronal Excitability, Promotes Synaptic Transmission, and Is Imprinted in the Brain of Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0098383

By:

Huang, Hsien-Sung;
Yoon, Bong-June;
Brooks, Sherian;
Bakal, Robert;
Berrios, Janet;
Larsen, Rylan S.;
Wallace, Michael L.;
Han, Ji Eun;
Chung, Eui Hwan;
Zylka, Mark J.;
Philpot, Benjamin D.

Publication type:

Article

Genetic Deletion of NR3A Accelerates Glutamatergic Synapse Maturation.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042327

By:

Henson, Maile A.;
Larsen, Rylan S.;
Lawson, Shelikha N.;
Pérez-Otaño, Isabel;
Nakanishi, Nobuki;
Lipton, Stuart A.;
Philpot, Benjamin D.;
Groc, Laurent

Publication type:

Article

Activity-Induced Remodeling of Olfactory Bulb Microcircuits Revealed by Monosynaptic Tracing.

Published in:

PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0029423

By:

Arenkiel, Benjamin R.;
Hasegawa, Hiroshi;
Yi, Jason J.;
Larsen, Rylan S.;
Wallace, Michael L.;
Philpot, Benjamin D.;
Wang, Fan;
Ehlers, Michael D.

Publication type:

Article

Activity-dependent regulation of calcium-binding proteins in the developing rat olfactory bulb.

Published in:

Journal of Comparative Neurology, 1997, v. 387, n. 1, p. 12, doi. 10.1002/(SICI)1096-9861(19971013)387:1<12::AID-CNE2>3.0.CO;2-Q

By:

Philpot, Benjamin D.;
Lim, Jae H.;
Brunjes, Peter C.

Publication type:

Article

Pinceau Organization in the Cerebellum Requires Distinct Functions of Neurofascin in Purkinje and Basket Neurons during Postnatal Development.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 14, p. 4724, doi. 10.1523/JNEUROSCI.5602-11.2012

By:

Buttermore, Elizabeth D.;
Piochon, Claire;
Wallace, Michael L.;
Philpot, Benjamin D.;
Hansel, Christian;
Bhat, Manzoor A.

Publication type:

Article

NrCAM Deletion Causes Topographic Mistargeting of Thalamocortical Axons to the Visual Cortex and Disrupts Visual Acuity.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 4, p. 1545, doi. 10.1523/JNEUROSCI.4467-10.2011

By:

Demyanenko, Galina P.;
Riday, Thorfinn T.;
Tran, Tracy S.;
Dalal, Jasbir;
Darnell, Eli P.;
Brennaman, Leann H.;
Sakurai, Takeshi;
Grumet, Martin;
Philpot, Benjamin D.;
Maness, Patricia F.

Publication type:

Article

Conditional Knock-Out of K<sub>ir</sub>4.1 Leads to Glial Membrane Depolarization, Inhibition of Potassium and Glutamate Uptake, and Enhanced Short-Term Synaptic Potentiation.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 42, p. 11354, doi. 10.1523/JNEUROSCI.0723-07.2007

By:

Djukic, Biljana;
Casper, Kristen B.;
Philpot, Benjamin D.;
Lih-Shen Chin;
McCarthy, Ken D.

Publication type:

Article

Developmental Switch in the Contribution of Presynaptic and Postsynaptic NMDA Receptors to Long-Term Depression.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 37, p. 9835, doi. 10.1523/JNEUROSCI.5494-06.2007

By:

Corlew, Rebekah;
Yun Wang;
Ghermazien, Haben;
Erisir, Alev;
Philpot, Benjamin D.

Publication type:

Article

Glycine receptors support excitatory neurotransmitter release in developing mouse visual cortex.

Published in:

Journal of Physiology, 2012, v. 590, n. 22, p. 5749, doi. 10.1113/jphysiol.2012.241299

By:

Kunz, Portia A.;
Burette, Alain C.;
Weinberg, Richard J.;
Philpot, Benjamin D.

Publication type:

Article

Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.11123

By:

Lei Xing;
Larsen, Rylan S.;
Bjorklund, George Reed;
Xiaoyan Li;
Yaohong Wu;
Philpot, Benjamin D.;
Snider, William D.;
Newbern, Jason M.

Publication type:

Article

Sleep EEG signatures in mouse models of 15q11.2-13.1 duplication (Dup15q) syndrome.

Published in:

Journal of Neurodevelopmental Disorders, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s11689-024-09556-7

By:

Saravanapandian, Vidya;
Madani, Melika;
Nichols, India;
Vincent, Scott;
Dover, Mary;
Dikeman, Dante;
Philpot, Benjamin D.;
Takumi, Toru;
Colwell, Christopher S.;
Jeste, Shafali;
Paul, Ketema N.;
Golshani, Peyman

Publication type:

Article

Regional analysis of myelin basic protein across postnatal brain development of C57BL/6J mice.

Published in:

Frontiers in Neuroanatomy, 2025, p. 1, doi. 10.3389/fnana.2025.1535745

By:

Ozarkar, Siddhi S.;
Patel, Ridthi K. R.;
Vulli, Tasmai;
Friar, Carlee A.;
Burette, Alain C.;
Philpot, Benjamin D.

Publication type:

Article

Transcription factor 4 expression in the developing non-human primate brain: a comparative analysis with the mouse brain.

Published in:

Frontiers in Neuroanatomy, 2024, p. 1, doi. 10.3389/fnana.2024.1478689

By:

Burette, Alain C.;
Vihma, Hanna;
Smith, Audrey L.;
Ozarkar, Siddhi S.;
Bennett, Jeff;
Amaral, David G.;
Philpot, Benjamin D.

Publication type:

Article