Works by Philipsen, Sjaak
Results: 54
Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects.
- Published in:
- Developmental Dynamics, 2007, v. 236, n. 10, p. 2970, doi. 10.1002/dvdy.21322
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- Article
Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects.
- Published in:
- Developmental Dynamics, 2007, v. 236, n. 8, p. 2235, doi. 10.1002/dvdy.21222
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- Publication type:
- Article
The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation.
- Published in:
- PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0208659
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- Article
Transcription factor Sp4 is required for hyperalgesic state persistence.
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- PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0211349
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- Article
Erythroid overexpression of C/EBP? in transgenic mice affects ?-globin expression and fetal liver erythropoiesis.
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- EMBO Journal, 2000, v. 19, n. 21, p. 5856, doi. 10.1093/emboj/19.21.5856
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- Article
Activation of the ß globin locus by transcription factors and chromatin modifiers.
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- EMBO Journal, 2000, v. 19, n. 18, p. 4986, doi. 10.1093/emboj/19.18.4986
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- Article
Transcription factor Sp3 is essential for post-natal survival and late tooth development.
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- EMBO Journal, 2000, v. 19, n. 4, p. 655, doi. 10.1093/emboj/19.4.655
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- Article
Erythroid Krüppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the ß-globin locus control region.
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- EMBO Journal, 1998, v. 17, n. 8, p. 2334, doi. 10.1093/emboj/17.8.2334
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- Publication type:
- Article
Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B.
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- Human Genomics, 2020, v. 14, n. 1, p. N.PAG, doi. 10.1186/s40246-020-00283-3
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- Publication type:
- Article
Effects of three Sp1 motifs on the transcription of the FGF-4 gene.
- Published in:
- Molecular Reproduction & Development, 2000, v. 57, n. 1, p. 4, doi. 10.1002/1098-2795(200009)57:1<4::AID-MRD3>3.0.CO;2-I
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- Article
Identification and in silico structural analysis of Gallus gallus protein arginine methyltransferase 4 ( PRMT4).
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- FEBS Open Bio, 2017, v. 7, n. 12, p. 1909, doi. 10.1002/2211-5463.12323
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- Publication type:
- Article
Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene.
- Published in:
- Genes to Cells, 2001, v. 6, n. 8, p. 689, doi. 10.1046/j.1365-2443.2001.00455.x
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- Publication type:
- Article
ASH1L (a histone methyltransferase protein) is a novel candidate globin gene regulator revealed by genetic study of an English family with beta-thalassaemia unlinked to the beta-globin locus.
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- British Journal of Haematology, 2016, v. 175, n. 3, p. 525, doi. 10.1111/bjh.14256
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- Publication type:
- Article
Chtop is a component of the dynamic TREX mRNA export complex.
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- EMBO Journal, 2013, v. 32, n. 3, p. 473, doi. 10.1038/emboj.2012.342
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- Publication type:
- Article
A Twenty-Five Year Prospective Clinical Review and Family Studies Revealed New Globin Gene Regulators for Hb F Induction.
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- 2019
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- Abstract
Sp2 is the only glutamine-rich specificity protein with minor impact on development and differentiation in myelinating glia.
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- Journal of Neurochemistry, 2017, v. 140, n. 2, p. 245, doi. 10.1111/jnc.13908
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- Article
TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis.
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- Molecular & Cellular Biology, 2015, v. 35, n. 12, p. 2103, doi. 10.1128/MCB.01370-14
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- Publication type:
- Article
Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04126-6
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- Publication type:
- Article
Hereditary persistence of fetal hemoglobin in two patients with KLF1 haploinsufficiency due to 19p13.2-p13.12/13 deletion.
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- American Journal of Hematology, 2017, v. 92, n. 1, p. E2, doi. 10.1002/ajh.24574
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- Article
Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the α globin cluster.
- Published in:
- Human Molecular Genetics, 2001, v. 10, n. 4, p. 371, doi. 10.1093/hmg/10.4.371
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- Publication type:
- Article
Author Correction: Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice.
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- 2023
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- Correction Notice
Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36409-z
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- Publication type:
- Article
Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36409-z
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- Publication type:
- Article
Targeted Protein Degradation as a Promising Tool for Epigenetic Upregulation of Fetal Hemoglobin.
- Published in:
- ChemMedChem, 2020, v. 15, n. 24, p. 2436, doi. 10.1002/cmdc.202000574
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- Publication type:
- Article
Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model - role of tumor stroma cells.
- Published in:
- BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-40
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- Publication type:
- Article
Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model - role of tumor stroma cells.
- Published in:
- 2014
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- Publication type:
- journal article
The return of Romeo. Scientists' international mobility and the future of research in Europe.
- Published in:
- EMBO Reports, 2006, v. 7, n. 11, p. 1067, doi. 10.1038/sj.embor.7400845
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- Publication type:
- Article
A tissue‐specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse.
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- Nucleic Acids Research, 2003, v. 31, n. 18, p. 5405, doi. 10.1093/nar/gkg723
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- Publication type:
- Article
SURVEY AND SUMMARY A tale of three fingers: the family of mammalian Sp/XKLF transcription factors.
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- Nucleic Acids Research, 1999, v. 27, n. 15, p. 2991, doi. 10.1093/nar/27.15.2991
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- Publication type:
- Article
Endothelial Sp1/Sp3 are essential to the effect of captopril on blood pressure in male mice.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41567-1
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- Publication type:
- Article
Nucleotide changes in the γ-globin promoter and the (AT)<sub>x</sub>N<sub>y</sub>(AT)<sub>z</sub> polymorphic sequence of βLCRHS-2 region associated with altered levels of HbF.
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- European Journal of Human Genetics, 1999, v. 7, n. 3, p. 345, doi. 10.1038/sj.ejhg.5200284
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- Publication type:
- Article
Reflections on the European Union Eurythron Network Meeting "Molecular Control of Erythropoiesis," September 22-23, 2005, Istituto Superiore Di Sanità, Rome, Italy.
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- Stem Cells, 2006, v. 24, n. 11, p. 2478, doi. 10.1634/stemcells.2006-0121
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- Article
Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.
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- Nature Genetics, 2011, v. 43, n. 6, p. 607, doi. 10.1038/ng.825
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- Publication type:
- Article
Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach.
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- Nature Genetics, 2011, v. 43, n. 4, p. 295, doi. 10.1038/ng.785
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- Publication type:
- Article
c AMP response element-binding protein 1 is required for hydroxyurea-mediated induction of γ-globin expression in K562 cells.
- Published in:
- Clinical & Experimental Pharmacology & Physiology, 2012, v. 39, n. 6, p. 510, doi. 10.1111/j.1440-1681.2012.05702.x
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- Publication type:
- Article
Genetic Polymorphisms Associated with Fetal Hemoglobin (HbF) Levels and F-Cell Numbers: A Systematic Review of Genome-Wide Association Studies.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 21, p. 11408, doi. 10.3390/ijms252111408
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- Article
An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells.
- Published in:
- Nature, 2000, v. 406, n. 6795, p. 519, doi. 10.1038/35020086
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- Article
Identification of a novel distal regulatory element of the human Neuroglobin gene by the chromosome conformation capture approach.
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- Nucleic Acids Research, 2017, v. 45, n. 1, p. 115, doi. 10.1093/nar/gkw820
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- Publication type:
- Article
Chtop (Chromatin target of Prmt1) auto-regulates its expression level via intron retention and nonsense-mediated decay of its own mRNA.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 20, p. 9847, doi. 10.1093/nar/gkw831
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- Article
Comparison of the PU.1 transcriptional regulome and interactome in human and mouse inflammatory dendritic cells.
- Published in:
- Journal of Leukocyte Biology, 2021, v. 110, n. 4, p. 735, doi. 10.1002/JLB.6A1219-711RRR
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- Article
Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors.
- Published in:
- Epigenetics & Chromatin, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13072-019-0282-9
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- Publication type:
- Article
A Dual Reporter Mouse Model of the Human β-Globin Locus: Applications and Limitations.
- Published in:
- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051272
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- Publication type:
- Article
Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction.
- Published in:
- PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010312
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- Publication type:
- Article
Specificity Protein 2 (Sp2) Is Essential for Mouse Development and Autonomous Proliferation of Mouse Embryonic Fibroblasts.
- Published in:
- PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009587
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- Publication type:
- Article
5'HS5 of the Human β-globin Locus Control Region Is Dispensable for the Formation of the β-globin Active Chromatin Hub.
- Published in:
- PLoS ONE, 2008, v. 3, n. 5, p. 1, doi. 10.1371/journal.pone.0002134
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- Publication type:
- Article
Transcription Factor GATA1 Is Dispensable for Mast Cell Differentiation in Adult Mice.
- Published in:
- Molecular & Cellular Biology, 2014, v. 34, n. 10, p. 1812, doi. 10.1128/MCB.01524-13
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- Publication type:
- Article
Erythropoietic Defect Associated with Reduced Cell Proliferation in Mice Lacking the 26S Proteasome Shuttling Factor Rad23b.
- Published in:
- Molecular & Cellular Biology, 2013, v. 33, n. 19, p. 3879, doi. 10.1128/MCB.05772-11
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- Article
Regulation of GATA Factor Expression Is Distinct between Erythroid and Mast Cell Lineages.
- Published in:
- Molecular & Cellular Biology, 2012, v. 32, n. 23, p. 4742, doi. 10.1128/MCB.00718-12
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- Article
Friend of Prmt1, a Novel Chromatin Target of Protein Arginine Methyltransferases.
- Published in:
- Molecular & Cellular Biology, 2010, v. 30, n. 1, p. 260, doi. 10.1128/MCB.00645-09
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- Publication type:
- Article
Transcription Factor Sp3 Knockout Mice Display Serious Cardiac Malformations.
- Published in:
- Molecular & Cellular Biology, 2007, v. 27, n. 24, p. 14, doi. 10.1128/MCB.01350-07
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- Publication type:
- Article